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Hubungan Profil Lipid dan Kejadian Migren pada Karyawan di Jakarta Satyasari, Daniella; Larasari, Andira; Faradilla, Meutia Atika; Anastasya, Karina Shasri
Bioscientist : Jurnal Ilmiah Biologi Vol. 13 No. 1 (2025): March
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v13i1.14885

Abstract

One of the risk factor for migraines is an elevated lipid profile. The most significant of the primary lipoproteins that causes atherosclerosis and readily binds to blood vessel walls is LDL. Because lipoprotein A (Lp(a)) levels have an atherogenic ApoA structure, increasing oxidative stress and fat oxidation can lead to endogenous vascular injury. Cross-sectional design was used to perform this study from October 2023 to June 2024 in Universitas Trisakti, Faculty of Medicine. The purpose of this study is to evaluate the association between the lipid level and the incidence of migraines among employees in Jakarta. The target population consists of Jakarta's private employees. With a total sample size of 66 employees that meet the inclusion and exclusion criteria, the study sample will be drawn using the sequential sampling method. The study's findings highlighted that high LDL (p=0.002) and total cholesterol (p=0.0001) had a significant relationship with migraines, whereas HDL, triglycerides, and Lp(a) had an insignificant link with the incidence of migraine (p>0.05). The study concluded that LDL is a powerful predictor of migraine occurrence and has a significant association with migraine.
Stress and Traumatic Related Disorder pada Konten Moderator: Tinjauan Pustaka Izehaga SJ, Muhammad; Devina V, Klara; Dwi Lestari, Ade; Ridwan, Alvin Mohamad; Satyasari, Daniella
Jurnal Sehat Indonesia (JUSINDO) Vol. 6 No. 01 (2024): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v6i01.88

Abstract

Peningkatan insiden gangguan mental terkait stres dan trauma di antara pekerja konten moderator kini semakin diakui sebagai isu kesehatan mental yang penting. Tugas yang meliputi penyaringan dan penghapusan konten yang tidak sesuai atau melanggar norma komunitas sering kali dilakukan dalam kondisi yang tidak terlihat oleh publik karena sifat pekerjaan mereka yang sensitif. Paparan berulang terhadap materi yang mengganggu secara psikologis ini merupakan salah satu bahaya psikososial yang dapat menyebabkan penyakit akibat kerja, berupa masalah kesehatan mental, termasuk trauma and stressor-related disorder. Realitas ini menyoroti kebutuhan akan pendekatan yang lebih berorientasi pada kemanusiaan dalam mengelola pekerjaan ini, serta pentingnya strategi pendukung untuk meminimalisir risiko gangguan kesehatan mental mereka. Penelitian ini bertujuan untuk mengkaji dampak kesehatan mental, terutama gangguan terkait trauma dan stres, pada konten moderator, suatu profesi yang seringkali tersembunyi dari perhatian publik. Peneliti melakukan tinjauan literatur berdasarkan relevansi topik ini. Semua basis data dicari melalui Google Scholar, PubMed, dan ResearchGate dengan menggunakan kata kunci Stress and traumatic related disorder pada konten moderator. Hasil dari penelitian ini menunjukkan prevalensi yang signifikan dari gangguan mental ini di kalangan pekerja, namun masih terdapat kekurangan dalam penelitian yang lebih mendalam dan luas mengenai topik ini. Kombinasi psikoterapi dan antidepresan golongan SSRI bisa menjadi pilihan utama untuk menatalaksana kasus trauma and stressor-related disorder pada konten moderator.
Hubungan Kadar Karbon Monoksida dengan Gambaran Psikopatologi dan Kognitif pada Pengemudi Ojek Online Rorong, Agnes Tineke Waney; Lintuuran, Rivo Mario Warouw; Velyani, Dyani Pitra; Satyasari, Daniella; Fitriana, Ika Nur
Jurnal Sehat Indonesia (JUSINDO) Vol. 6 No. 02 (2024): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v6i02.103

Abstract

Keterpaparan bahan bakar bensin, di antaranya karbon-monoksida (CO) dalam jangka panjang merupakan konsekuensi kerja pengemudi ojek online (ojol). Afinitas tinggi CO dengan hemoglobin (COHb) berpotensi toksik terhadap kesehatan. Risiko gangguan jiwa meliputi depresi, cemas, somatoform dan kognisi. Penelitian ini bertujuan menilai hubungan kadar CO dengan psikopatologi dan kognisi pada pengemudi ojek online. Metode penelitian ini menggunakan desain potong lintang dengan populasi target supir ojek online Jabodetabek bertempat di kampus B Universitas Trisakti Jakarta. Pengukuran gambaran psikopatologi menggunakan kuesioner SRQ-20, kognisi dengan MMSE dan COHb (kadar tinggi ³ 3,5%). Hasil menunjukkan 123 responden dengan rerata usia 37,2 tahun; gender laki-laki 80,5%; pendidikan SMA 74%; pendapatan bulanan <= Rp. 4,9 juta (94,3%). Kadar COHb laki-laki 0,8x lebih tinggi dibanding perempuan yang seluruhnya normal. Terdapat hubungan signifikan antara gender dan kadar COHb (p=0,029), dan antara kadar COHb dengan masa kerja > 5 tahun (p=0,029). Tidak terdapat hubungan signifikan antara fungsi kognitif dan kadar COHb. Gambaran psikopatologi sebanyak 26,8% namun tidak terdapat hubungan dengan kadar COHb (p=0,778). Penelitian berikutnya direkomendasikan untuk melihat faktor-faktor lain yang dapat memberi kontribusi pada psikologi dan kognitif pengemudi ojek online.
Hubungan Kapasitas Cadangan Kognitif dan Kualitas Hidup Lansia Rorong, Agnes Tineke Waney; Lintuuran, Rivo Mario Warouw; Velyani, Dyani Pitra; Satyasari, Daniella; Fitriana, Ika Nur
Jurnal Locus Penelitian dan Pengabdian Vol. 5 No. 1 (2026): JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v5i1.5424

Abstract

The elderly are vulnerable to geriatric problems or syndromes, including cognitive impairment that can progress to dementia, leading to a decreased quality of life. One factor that can prevent cognitive problems or impairment in the elderly is cognitive reserve capacity, the brain's ability to optimize its function and prevent damage that can affect cognition. This study aims to analyze the relationship between cognitive reserve capacity and quality of life in the elderly. A cross-sectional study was conducted on 109 elderly in Krendang Village, West Jakarta, in February 2024. Inclusion criteria included elderly aged 60-79 years who were able to read, write, and communicate in Indonesian, were in good health or had controlled medical conditions, and were able to hear and see well. The variables studied were cognitive reserve capacity (education and employment, neuroprotection, physical health risk factors, and mental health risk factors) and quality of life, as assessed by the WHOQoL-BREF instrument. Bivariate analysis was performed using the Pearson correlation test to determine the correlation between cognitive reserve capacity and quality of life. Multivariate analysis using linear regression was performed to identify factors in cognitive reserve capacity that significantly influence quality of life. A total of 109 subjects (mean age 66.2 years with a standard deviation of 4.59) participated in this study. The mean total cognitive reserve capacity score was 41.42 ± 6.79. The mean quality of life scores for the physical domain was 14.61 ± 2.41; the psychological domain 13.08 ± 1.93; the social relationships domain 13.19 ± 2.59; and the environmental domain 14.14 ± 1.97. Sociodemographic factors significantly associated with quality of life included gender, education, family residence, and financial resources. There was a significant correlation between cognitive reserve capacity and quality of life (p<0.05), with moderate correlations in the physical domain (r=0.42) and social relationships (r=0.42), and weak correlations in the psychological domain (r=0.26) and environmental domain (r=0.26). The R2 value was 14.5%. Cognitive reserve capacity is associated with quality of life in older adults, particularly in the physical domain and social relationships.
The Relationship Between Nutritional Status with Malondialdehyde (MDA) and Vitamin D Level Anastasya, Karina Shasri; Faradilla, Meutia Atika; Satyasari, Daniella; Larasari, Andira
The Avicenna Medical Journal Vol. 6 No. 2 (2025): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v6i2.47151

Abstract

Background: Nutritional status has been found to be correlated with malondialdehyde (MDA) profiles in the blood. MDA is a marker of oxidative stress in the body and is the final product of lipid peroxidation chain reactions. The long-term undernutrition and excess status will be closely related to metabolic disorders and degenerative diseases. Street cleaning staff are often exposed to free radicals that will improve lipid peroxidation, which will also break down into MDA. Vitamin D serum levels have an inverse correlation with adipose tissue mass, where the higher the BMI and body fat mass of a person, the lower the levels of vitamin D serum. The purpose of this study was to determine the relationship of nutritional status with MDA and vitamin D levels in the blood. Methods: This research will be conducted from July 2024 to February 2025, using a cross-sectional design at the Faculty of Medicine, Trisakti University, with the target population being the street cleaning staff in Jakarta. The samples were taken by consecutive sampling for all street cleaning staff who met the inclusion and exclusion criteria, with a total of 76 samples. Results: The results showed that there was no significant relationship between nutritional status with MDA and vitamin D, but there was a significant relationship between vitamin D and MDA (r=0.190; p=0.047). Conclusion: Higher BMI is associated with a relative reduction in muscle mass percentage and a substantial increase in visceral adiposity, irrespective of sex. These findings suggest that BMI alone may not adequately represent body composition or metabolic risk and support the routine use of body composition assessment as a complementary tool in clinical obesity evaluation. Keywords: Nutritional status, MDA, vitamin D