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All Journal Jurnal Kedokteran Brawijaya Jurnal Ilmiah Kedokteran Wijaya Kusuma Calvaria Medical Journal Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Herni Suprapti, Herni
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : Calvaria Medical Journal

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EFEKTIVITAS ANTIVIRUS CIDOFOVIR PADA PASIEN CACAR MONYET DENGAN GEJALA BERAT Signa Radityatama, I Gusti Lanang Agung; Suprapti, Herni
Calvaria Medical Journal Vol 2 No 1 (2024): Edisi Juni 2024 (available online Juli 2024)
Publisher : Institute for Research and Community Services (LPPM) of University of Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/cmj.v2i1.33

Abstract

Background: Monkey pox is an infectious disease caused by viruses of the family Poxviridae, genus Orthopoxvirus, which can infect humans, vertebrates and arthropods. Symptoms of monkey pox include increased body temperature, headache, muscle aches, weakness, swollen lymph nodes in the neck, armpits and groin, and skin rashes. Giving antivirals is very effective in treating monkey pox infections caused by the monkey pox virus. Cidofovir is an antiviral that is given intravenously, for the treatment of monkey pox patients. The effectiveness of cidofovir in cases of monkeypox in humans is still uncertain. However, this drug has been shown to fight poxviruses in in vitro and animal studies. Based on this background, researchers are interested in conducting research on "Effectiveness of the Antiviral Cidofovir in Monkeypox Patients with Severe Symptoms". Method: This research is descriptive qualitative research with library research. Search for articles in this literature review using the 2010-2022 database with keywords according to the topic. After getting the reference sources, they were filtered until they got 25 journals consisting of 15 international journals, 10 national journals, and 2 textbooks. Result: The results of a literature study in 11 research journals were found to show the effectiveness of the antiviral cidofovir in monkey pox patients with severe symptoms, with recovery between 14-21 days at the fastest and between 35-52 days at the longest. Conclusion: The antiviral cidofovir is effective for treating monkeypox with severe symptoms. Apart from that, it was also found that the cure rate for monkey pox patients treated with cidofovir reached 57% -85% depending on the severity of the disease.
Overview of Compliance and Satis Gambaran Kepatuhan dan Kepuasan Terhadap Terapi Hipertensi pada Pasien Hipertensi di Puskesmas Dukuh Kupang Surabaya Periode Oktober-Desember 2023 Lali, Maria Celina; Suprapti, Herni
Calvaria Medical Journal Vol 3 No 1 (2025): Edisi Juni 2025
Publisher : Institute for Research and Community Services (LPPM) of University of Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/cmj.v3i1.149

Abstract

Latar Belakang: Hipertensi merupakan kondisi medis yang ditandai oleh peningkatan tekanan darah secara persisten melebihi batas normal, yaitu ≥140/90 mmHg. Meskipun dapat disembuhkan secara permanen, hipertensi tetap bisa dikendalikan melalui pengobatan yang tepat. Dalam hal ini, kepatuhan pasien terhadap terapi memegang peranan penting guna mencegah komplikasi jangka panjang. Tujuan: Penelitian ini bertujuan untuk menggambarkan tingkat kepatuhan serta tingkat kepuasan pasien terhadap terapi hipertensi di Puskesmas Dukuh Kupang, Surabaya, selama periode Oktober hingga Desember 2023. Metode: Penelitian ini menggunakan desain deskriptif dengan pendekatan kuantitatif. Data dikumpulkan melalui penyebaran kuesioner kepada 50 pasien hipertensi yang menjalani pengobatan di Puskesmas Dukuh Kupang. Kepatuhan terapi diukur menggunakan instrumen Morisky Medication Adherence Scale (MMAS-8), sedangkan tingkat kepuasan pasien terhadap pengobatan dievaluasi melalui Treatment Satisfaction Questionnaire for Medication (TSQM). Hasil: Dari total 50 responden, sebanyak 28% pasien menunjukkan tingkat kepatuhan tinggi, 36% dengan tingkat kepatuhan sedang, dan 36% tergolong rendah. Dari segi kepuasan terhadap layanan terapi obat hipertensi, mayoritas pasien berada dalam kategori cukup puas (74%), sedangkan sisanya (26%) mengaku sangat puas. Kesimpulan: Secara umum, tingkat kepatuhan dan kepuasan terhadap terapi hipertensi di Puskesmas Dukuh Kupang tergolong cukup baik. Namun, masih dibutuhkan upaya tambahan, khususnya untuk pasien dengan kepatuhan rendah dan kepuasan yang belum optimal, melalui peningkatan edukasi serta perbaikan mutu layanan kesehatan.  
Hubungan Kepatuhan Penggunaan Obat dengan Keberhasilan Terapi Hipertensi di RSUD Waru Pamekasan pada Tahun 2024 Putri, Diah Arrizah; Suprapti, Herni
Calvaria Medical Journal Vol 3 No 2 (2025): Edisi Desember 2025
Publisher : Institute for Research and Community Services (LPPM) of University of Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/2epgky32

Abstract

Background: Adherence is one of the definite requirements for for improving therapeutic effectiveness and the patient’s quality of life. Low adherence to prescribed antihypertensive medications is a major factor in uncontrolled hypertension. The patien’s disobedience to the use of drugs can be caused by boredom in taking hypertension medication, and patients often do not remember the time to take medication. Pameksan is one of the districts in East Java, the prevalence of hyeprtension patients in pamekasan has increased in 2017 around 23,16 %. Therefore, this study was conducted to determine whether there is a relationship between compliance with drug use and the success of hypertension therapy at RSUD Waru Pamekasan. Research Methods: This analytical observational study employed a cross-sectional design involving 32 hypertensive patients treated at Waru Pamekasan Hospital. Respondents were selected using a nonprobability sampling technique. The association between variables was analyzed using the chi-square test. Result of Research and Conclusion: The findings indicate a significant association between medication adherence and the therapeutic success of hypertension management among patients at Waru Pamekasan Hospital in 2024, supported by a p-value < 0.05.
Co-Authors Budi Arief Waskito, Budi Arief Budianto, Nugroho Eka Wirawan Ernawati Ernawati Lali, Maria Celina Putri, Diah Arrizah Setijowati, Eva Diah Signa Radityatama, I Gusti Lanang Agung Wulandari, Retno Dwi Yuhasnara, Balqis Agita Yundari, Yundari