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All Journal Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Abdidas Journal of Community Development Jurnal EduHealth Prosiding Seminar Nasional COSMIC Kedokteran
Titiek Sunaryati, Titiek
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Health Professions Industrial & Manufacturing Engineering Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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EFFECT OF GARLIC EXTRACT ON SMALL INTESTINE TO INCREASE INTERFERON γ IN WHITE MALE BALB/C MICE Sunaryati, Titiek
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 2 (2012): Edisi Oktober 2012
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

     Common cold is an infectious disease that is caused by viruses. The purpose of this study is to explain how garlic extract can increase body  immunity.     This was experimental study using white male BALB/c strain mice, 10 weeks old with bodyweight of 25-35 grams. Group 1 received placebo (CMC Na) for 14 days. Group 2 received 10mg/kg BW garlic extract for 14 days, and group 3 received 20mg/kg BW garlic extract for 14 days. After 14 days mice were sacrified then  intestines were removed and processed in the paraffin block, then were stained with immunohistochemistry.     There was one  variable such as the amount of cell that produce interferon γ. Data were analyzed by analysis of variance Brown Forsythe, any significant different was further analyzed by using Games Howell in the significant level of 0.05. There were significant difference between groups those received placebo, 10mg/kgBw garlic extract, and 20mg/kgBw garlic extract in each variables.     Garlic extract can increase body immunity via increase in the amount of cell that produce interferon γ. 
THE EFFECT OF Tamarindus indica EXTRACT ON WEIGHT GAIN ON Rattus novergicus RATS WITH OBESE DIET FOOD Putri, Candra Rini Hasanah; Sunaryati, Titiek
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 6, No 1 (2017): Edisi Maret 2017
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Obesity is a health problem whose prevalence tends to increase in Indonesia. Obesity becomes a concern, because it is one of the parameters that often followed by impaired of glucose tolerance in the metabolic syndrome. In Indonesia, Tamarindus indica is believed as a body slimming substance so it has possibility to become an alternative therapy that is easily available and cheap for obesity. The purpose of this study was to determine the ability of Tamarindus indica in inhibiting obesity. This experiment used 28 male Wistar strains in 2-3 months age that were divided into groups: group 1 (negative control, normal diet without Tamarindus indica), group 2 (positive control, obese diet without Tamarindus indica), group 3 (obese diet + Tamarindus indica 2700mg/kg BW), and group 4 (obese diet + Tamarindus indica 3600mg/kg BW). Measurement were performed in the first day after acclimization before treatment (day 8), and repeated weekly afterwards, ie at day 15, 22, 29, 36, and 43. Anova and Tukey Simultaneous statistics test were performed to see the differences in wight gain per week compared with the first week of study, then compared between groups.  Furthermore, a virtual screening that called insilico bioinformatics analyzes was performed to test the binding activity between quercetin and rutin (compounds in Tamarindus indica) with fatty acid synthase, an enzym that plays a role in de novo synthesis of fatty acids. Tamarindus indica was shown to significantly inhibit weight gain in rats with obese diet food (P=0.000), but differences dose of Tamarindus indica did not appear to have significant effect to inhibit obesity (P=0.321). The ability of Tamarindus indica is due to the compounds quercetin and rutin, where these two ingredients estimated to have the ability to inhibit fatty acid synthase with high strength. 
Penyuluhan Pengaruh Indeks Masa Tubuh (IMT), Kadar Gula Darah dan Prilaku Diet Tinggi Serat untuk Mencegah Kanker Kolorektal Sugeng, Maria Widijanti; Agusaputra, Harman; Inawati, Inawati; Sunaryati, Titiek
Jurnal Abdidas Vol. 4 No. 6 (2023): December, Pages 457 - 580
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdidas.v4i6.848

Abstract

Kanker kolorektal atau kanker usus besar merupakan kanker yang tersering di dunia menempati urutan ketiga terbanyak, begitu juga di Indonesia juga menempati urutan ketiga dan diperkirakan akan semakin meningkat. Faktor pencetus kejadian kanker kolorektal biasanya adalah  makanan baik dari alkohol, makanan berlemak, makanan rendah serat dan tidak kalah pentingnya dikaitkan dengan obesitas dan diabetes. Angka kejadian obesitas tampaknya secara patomekanisme sering juga dihubungkan dengan kejadian diabetes dan ternyata juga merupakan pencetus kanker kolorektal. Bersamaan dengan meningkatkan insiden obesitas dan diabetes di Indonesia  yang merupakan faktor resiko kanker kolorektal. Penyuluhn Pengaruh Indeks Masa Tubuh (IMT), Kadar Gula Darah dan Prilaku Diet Tinggi Serat Untuk Mencegah Kanker Kolorektal dilakukan di Puskesmas Dukuh Kupang Surabaya. Penyuluhan tersebut menggunakan media poster, leaflet dan alat peraga dengan peserta sebanyak 40 orang,. Sebelum penyuluhan peserta diberikan kuesioner tentang kebiasaan makan sayuran serta pengetahuan tentang diabetes, obesitas dan kanker kolorektal. Kebiasaan makan sayur peserta cukup baik, 19 orang  (47,5%) makan sayur setiap hari, 15 orang (37,5%)makan sayur tiga kali seminggu dan hanya 4 orang (10%) makan sayur sekitar sekali per minggu.
Kursus Singkat Monitoring Perkembangan Balita Dalam Penanganan Stunting Sebagai Upaya Peningkatan Pengetahuan Kader Surabaya Hebat Inawati, Inawati; Sunaryati, Titiek; Agusaputra, Harman; Tania, Putu Oky Ari
Journal of Community Development Vol. 5 No. 2 (2024): December
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/comdev.v5i2.275

Abstract

Undernutrition is responsible for nearly 50% child deaths, especially in poor countries. Approximately 25% of toddlers worldwide experience stunted which is associated with mortality, cognitive impairment and reduced productivity. The mission of the Kementrian Kesehatan is to improve the level of public health through community empowerment (Posyandu). especially in Surabaya with the empowerment of Kader Surabaya Hebat (KSH). Wonokromo District, with an area of ​​8.42 Km2 and occupying 2.55% of the area of ​​Surabaya city, has 3 access to primary health facilities, covering 6 sub-districts (Kelurahan). The ratio of community health centers per Wonokromo sub-district is 1.9, this shows that the coverage of primary health access in Wonokromo is quite good. KSH knowledge needs to be improved through education, short courses and monitoring. The aim of this Pengabdian  activity is to increase knowledge regarding monitoring the toddlers development, especially in handling stunting toddlers. This activity was able to increase the knowledge of KSH as shown by an increase in the highest score of 100, from 10% to 54.2%. Increasing KSH knowledge is a first step so that it can be applied to the community, namely toddlers in the Wonokromo health center area, so that monitoring of stunting toddlers can run and can prevent or even reduce the stunting rate in Wonokromo.
STUDI LITERATUR: HUBUNGAN ANTARA PEROKOK PASIF DENGAN KEJADIAN KANKER PAYUDARA PADA WANITA Hilungara, Umbu Reku Djawa Tana; Sunaryati, Titiek; Idawati, Ira
Prosiding Seminar Nasional COSMIC Kedokteran Vol 3 (2025): Edisi 2025
Publisher : Lembaga Penelitian Dan Pengabdian Kepada Masyarakat Universitas Wijaya Kusuma Surabaya

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Abstract

Kanker payudara merupakan keganasan paling umum terjadi di seluruh dunia dan salah satu penyebab utama kematian pada Wanita setelah kanker pernafasan. Salah satu faktor yang menyebakan kanker payudara ialah asap rokok. Penelitian ini memiliki tujuan umuntuk mengetahui adanya hubungan antara perokok pasif dengan kejadian kanker payudara pada wanita. Penelitian ini menggunakan metode literature review yang bersifat deskriptif dengan pengumpulan data/informasi, analisis dan pemecahan masalah. Beberapa penelitian menunjukkan bahwa kultur sel yang diekspose dengan asap rokok akan meningkatkan level NF-kB aktif dan memacu ekspresi protein cyclin D, protein yang sangat diperlukan untuk awal pembelahan sel. Dengan sifat yang demikian ini maka senyawa PAH juga akan dapat memicu perkembangan tumor lebih cepat lagi. Kesimpulannya ialah adanya hubungan antara perokok pasif dengan kejadian kanker payudara pada wanita.
The Relationship Between Hypertension and Uric Acid Levels Among Police Officers Aged 30–60 Years at the Pasuruan Police Resort Kusumaningtyas, Nisa Priamita; Sunaryati, Titiek; Sugeng, Maria Widjianti
Jurnal EduHealth Vol. 16 No. 03 (2025): Jurnal EduHealt, Edition July - September , 2025
Publisher : Sean Institute

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Abstract

Hypertension and hyperuricemia are two metabolic conditions that frequently coexist and may lead to cardiovascular complications. This study was motivated by the high prevalence of hypertension and elevated uric acid levels among individuals in their productive age, particularly in high-stress occupations such as police officers. The aim of this research was to determine the relationship between hypertension and uric acid levels among police officers aged 30–60 years at the Pasuruan Police Department. This quantitative research used a cross-sectional design with an analytic approach. A purposive sampling technique was employed to select 60 respondents, and data were collected through blood pressure and uric acid level examinations. Data were analyzed using the Chi-Square test. Results showed that 83.3% of respondents had hypertension and 28.3% had hyperuricemia. The Chi-Square test indicated a significant relationship between hypertension and uric acid levels (p = 0.005). It can be concluded that there is a relationship between hypertension and uric acid levels, where individuals with hypertension are more likely to experience hyperuricemia. It is recommended that regular monitoring of blood pressure and uric acid levels be conducted among individuals in their productive age, along with the adoption of a healthy lifestyle as a promotive and preventive measure against further complications.
The Relationship Between Hypertension and Body Mass Index (BMI) Among Police Officers Aged 30–60 Years at the Pasuruan Police Resort Abadi, Vania Zemima Rahmadya; Sunaryati, Titiek; Sugeng, Maria Widjianti
Jurnal EduHealth Vol. 16 No. 03 (2025): Jurnal EduHealt, Edition July - September , 2025
Publisher : Sean Institute

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Abstract

Hypertension is one of the most common non-communicable diseases, often occurring without clear symptoms, making early detection difficult. One of the risk factors contributing to the occurrence of hypertension is an increase in Body Mass Index (BMI). Individuals with high BMI, particularly those categorized as overweight or obese, tend to have a higher risk of developing high blood pressure. This study aims to determine the relationship between hypertension and BMI among police officers aged 30 to 60 years, considering that this profession involves high levels of stress and workload, which can also impact cardiovascular health. The research employed a cross-sectional design with a total of 60 respondents. Data analysis was conducted using the Chi-Square test. The results showed a significant relationship between hypertension and BMI (p = 0.000), where the majority of respondents with hypertension had BMI values classified as overweight or obese. Therefore, regular monitoring of body weight and blood pressure is highly recommended, especially for high-risk professions such as police officers, to prevent more serious health complications in the future.
The Relationship Between Hypertension and Blood Glucose Levels Among Police Officers Aged 30–60 Years at the Pasuruan Police Resort Herdiana, Rency Angelika; Sunaryati, Titiek
Jurnal EduHealth Vol. 16 No. 03 (2025): Jurnal EduHealt, Edition July - September , 2025
Publisher : Sean Institute

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Abstract

Hypertension and elevated blood glucose levels are two chronic conditions that are often found concurrently and are major risk factors for cardiovascular disease. Although the relationship between the two has been extensively studied, specific data within certain professional groups such as police officers remain limited. This study aimed to examine the relationship between hypertension and blood glucose levels among police officers aged 30–60 years at the Pasuruan Police Resort. The study employed a cross-sectional design with a quantitative approach. The sample consisted of 60 police officers selected using purposive sampling. Data were obtained through blood pressure measurements and random blood glucose tests, and then analyzed using the Chi-Square test and Fisher’s Exact Test. The results showed that 83.3% of respondents had hypertension, and 13.3% of them had elevated blood glucose levels. Statistical analysis using Fisher’s Exact Test revealed no significant relationship between hypertension and blood glucose levels (p = 0.330). It can therefore be concluded that there is no significant association between hypertension and blood glucose levels among police officers aged 30–60 years at the Pasuruan Police Resort. Further research is needed, taking into account other risk factors such as dietary patterns, physical activity, and family medical history.
Co-Authors Abadi, Vania Zemima Rahmadya Candra Rini Hasanah Putri HARMAN AGUSAPUTRA Herdiana, Rency Angelika Hilungara, Umbu Reku Djawa Tana Idawati, Ira Inawati Inawati, Inawati Kusumaningtyas, Nisa Priamita Maria Widijanti Sugeng Putu Oky Ari Tania Sugeng, Maria Widjianti