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All Journal Althea Medical Journal Universa Medicina Jurnal Kreativitas PKM PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Penelitian dan Karya Ilmiah Lembaga Penelitian Universitas Trisakti Jurnal Abdimas Kesehatan Terpadu Jurnal Kedokteran Meditek
Lie Tanu Merijanti, Lie Tanu
Universitas Trisakti, Jakarta
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Increased matrix metalloproteinase-9 in male elderly with low 25-hydroxy-vitamin D Pusparini, Pusparini; Merijanti, Lie Tanu; Sudharma, Novia I.
Universa Medicina Vol 35, No 3 (2016)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2016.v35.171-180

Abstract

Background One of the extra-skeletal roles of vitamin D for health is associated with cardiovascular disease. Poor vitamin D status has been associated with vascular endothelial dysfunction. There were controversial results about the association between vitamin D deficiency and matrix metalloproteinase 9 (MMP-9) concentration. The purpose of the present study was to determine the concentrations of 25(OH) vitamin D [25(OH)D] in an elderly population and to find any association between 25(OH)D and MMP-9 concentrations.MethodsThis study was of cross-sectional design involving 160 male and female subjects aged 55–65 years, in South Jakarta, Indonesia. Determination of MMP-9 and 25(OH)D concentrations was done concurrently on subjects who met the inclusion and exclusion criteria after all study subjects had been selected. 25(OH)D and MMP-9 concentrations were assessed by direct competitive chemiluminescence immunoassay (CLIA) and enzyme-linked immunosorbent assay (ELISA) respectively. Statistical analysis used chi square and t tests.ResultsMean 25(OH)D concentration in the study subjects was 14.4 ± 6.4 ng/mL. A total of 68.8% of subjects had a 25(OH)D level of <20 ng/mL, and 31.2 % had a 25(OH)D level of >20 ng/mL.There was an increased MMP-9 concentration in male subjects with a 25(OH)D level of <20 ng/mL compared with subjects with 25(OH)D level of >20 ng/mL (p=0.011), but not among female subjects (p=0.809).ConclusionThe MMP-9 concentration was increased among male subjects with low level of (OH)D. This study confirmed that 25(OH)D concentration may have a potential role in endothelial function.
Decreased adiponectin level in adults with central obesity and low 25-hydroxy vitamin D level Pusparini, Pusparini; Merijanti, Lie Tanu; Lesmana, Alvina; Meiyanti, Meiyanti
Universa Medicina Vol 36, No 3 (2017)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2017.v36.205-213

Abstract

Background Vitamin D insufficiency is associated with obesity and central obesity, which is in turn associated with the accumulation of visceral fat. Visceral fat secretes adiponectin which has a role in the pathogenesis of the metabolic syndrome, diabetes mellitus and cerebrovascular disease. The aim of this study was to determine the relationship between serum 25-hydroxy vitamin D [25(OH)D] level and adiponectin level in adults with central obesity. Methods This study was a cross sectional study with 80 subjects with central obesity and 80 healthy subjects as controls. The age of the subjects ranged from 55 to 65 years. The data collection included anthropometry and blood biochemistry (lipid profile, fasting blood glucose, 25(OH)D, and adiponectin). The data were analyzed using independent t test with p <0.05.Results Mean waist circumference and 25(OH)D level in the central obesity group were 94.9 ± 7.8 cm and 14.3 ± 6.6 ng/mL, respectively, and in the control group 72.4 ± 5.0 cm and 19.2 ± 8.6 ng/mL respectively. There were significant differences in adiponectin level between the central obesity group and the control group at the 25(OH)D level of <20 ng/mL (p=0.001), but no significant differences between the two groups at the 25(OH)D level of ³20 ng/mL (p=0.538).Conclusion The central obesity subgroup with 25(OH)D level of <20 ng/mL have lower adiponectin levels compared with the control group. This study demonstrates the role of adiponectin as a link between insulin resistance and vitamin D status in adults.
Hypoglycemic effect of Phaleria macrocarpa (Scheff.) Boerl dry extract in healthy adults Meiyanti, Meiyanti; Margo, Eveline; Pusparini, Pusparini; Merijanti, Lie Tanu; Lesmana, Alvina
Universa Medicina Vol 37, No 3 (2018)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (828.359 KB) | DOI: 10.18051/UnivMed.2018.v37.195-202

Abstract

BackgroundThe prevalence of diabetes in Indonesia continues to increase and causes many complications. Fruits of Phaleria macrocarpa (Scheff.) Boerl. (PM) are used in the traditional health system of the Indonesians, as effective remedy in the management of diabetes mellitus. The aim of this study was to evaluate the effect and magnitude of doses of PM dry fruit extract (PME) on blood glucose levels in healthy adults.MethodsThis research was of pre-posttest design involving 30 healthy volunteer subjects aged 20-55 years receiving glucose loads. At pre-test the subjects were given orally 75 g glucose, and at post-test they were given PME at doses of 125 mg and 250 mg. Data collection included anthropometric examination and blood glucose level. The area under the curve (AUC) of blood glucose levels was measured at 0, 15, 30, 60, 120 and 180 minutes. Data analysis was performed using paired t-test with p <0.05.ResultsThe percentage of reduction in AUC between pre- and post-test after administration of PME 125 mg was 12.1% and significant (p=0.000). But the percentage of reduction in AUC between pre- and post-test after administration of PME 250 mg was 4.07% and not significant (p=0.06). The reduction in AUC between post-test PME 125 mg vs PME 250 mg showed significant results (p=0.011).Conclusion This study demonstrated that a dose of 125 mg Phaleria macrocarpa (Scheff.) Boerl. dry extract has a hypoglycemic effect in healthy adults, and may therefore be suitable for use as traditional anti-diabetic drug.
Penyuluhan Pentingnya Vitamin D untuk Kesehatan pada Pengemudi Ojek Online di Jakarta Pusparini Pusparini; Mario Mario; Lie Tanu Merijanti
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 6, No 7 (2023): Volume 6 No 7 2023
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v6i7.10030

Abstract

ABSTRAK Vitamin D merupakan vitamin yang sangat dibutuhkan oleh tubuh manusia. Indonesia merupakan negara dengan sumber sinar matahari yang sangat berlimpah, namun defisiensi vitamin D yang diderita oleh sebagian penduduknya cukup mengkhawatirkan. Banyak faktor yang menjadi penyebab kondisi defisiensi tersebut, salah satunya adalah pengetahuan yang rendah mengenai sumber dan pentingnya vitamin D untuk kesehatan. Sasaran untuk pengabdian kepada masyarakat (PkM) ini adalah pengemudi ojek online (ojol). Tujuan dari PkM ini adalah meningkatkan pengetahuan pengemudi ojol mengenai sumber dan pentingnya vitamin D untuk  kesehatan. Peserta yang hadir pada kegiatan ini berjumlah 30 orang pengemudi ojol di Jakarta. Dilakukan tes sebelum dan sesudah penyuluhan mengenai materi. Edukasi yang disampaikan memperlihatkan bahwa pengetahuan pengemudi ojol di Jakarta mengenai vitamin D masih rendah dan meningkat pasca dilakukan penyuluhan.  Diperlukan edukasi berkelanjutan pada pengemudi ojol mengenai vitamin D untuk kesehatan. Kata Kunci: Pengetahuan, Ojek Online, Sinar Matahari  Vitamin D  ABSTRACT Vitamin D was the very needed vitamin in human body. Indonesia was the country with  sunshine abundant throughout the year, but vitamin D deficient suffered by the inhabitants quite worrying. Many factors caused the deficient condition, one of them was poor knowledge about resource and importance of vitamin D for health. Target for this community service was online driver. The purpose of this community service was to improve knowledge of online driver about vitamin D for health. Thirty participant attended this activity. We did pre and post test about learning material. The result of this community service showed that there was poor knowlegde about vitamin D and increasing knowledge after presentation. Further education needed for online driver about vitamin D for health. Keywords:  Knowledge, Online Driver, Sunshine, Vitamin D
Penyuluhan Hipertensi serta Pelayanan Kesehatan pada Lansia di Cengkareng Barat Dian Mediana; Magdalena Wartono; Purnamawati Tjhin; Lie Tanu Merijanti; Kartini; Joice Viladelphia Kalumpiu; Dewi Hastuty; Kurniasari
JURNAL ABDIMAS KESEHATAN TERPADU Vol. 2 No. 1 (2023): Jurnal Abdimas Kesehatan Terpadu
Publisher : Fakultas Kedokteran Gigi, Universitas Trisakti bekerjasama dengan Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jakt.v2i1.16792

Abstract

Hypertension is a condition that is often found in primary health care, because the prevalence of hypertension in Indonesia is relatively high. According to RISKESDAS 2018, the prevalence of hypertension in Indonesia was 34.11%. Hypertension is a major public health problem, responsible for at least 45% of deaths from heart disease and 51% of deaths from stroke. The increasing prevalence of hypertension is caused by population growth, old age and risk factors for unhealthy dietary behavior. In addition to hypertension, through general health checks, other diseases can be found, especially degenerative diseases. In elderly it is important to carry out periodic checks because the higher the risk of degenerative diseases due to decreased the function of various organs of the body. The activities of Pengabdian Kepada Masyarakat are carried out by counseling and health care on 4th January 2023 to 42 participants aged ≥46 years (early elderly) at Panti Sosial Tresna Werdha Budi Mulia 4. The results of the counseling get a 43% increase in knowledge about hypertension. The results of the health care get diagnosis of 23% hypertension, 17% stroke, 17% neuralgia, 9% osteoarthritis, 9% diabetes mellitus, 9% cephalalgia, 6% gastritis, 6% dermatitis, and 4% anemia. It is hoped that this activity can run continuously to achieve better elderly health.
HUBUNGAN STRES AKADEMIK DENGAN KECENDERUNGAN GEJALA SOMATISASI PADA SISWA SMA DI ERA PANDEMI COVID-19 Widia Aina Rohmah; Merijanti, Lie Tanu
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 9, Nomor 1, Januari 2024
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v9i1.16487

Abstract

Sekolah beralih ke sistim pembelajaran serta ujian online di era pandemi covid- 19. Keadaan ini membuat perubahan proses belajar siswa dan kemungkinan dapat menyebabkan terjadinya stres akademik yang seringkali diikuti oleh timbulnya keluhan psikis. Penelitian ini bertujuan untuk meneliti hubungan stres akademik dengan timbulnya gejala somatisasi pada siswa SMA di era pandemi Covid-19. Studi dengan desain cross-sectional dengan teknik simple random sampling, dilakukan pada bulan September sampai Desember 2021, dan didapatkan sampel sebesar 102 responden. Kuesioner ESSA (Educational Stress Scale for Adolescents) digunakan sebagai instrumen pengukur stres akademik dan PHQ-15 (The Patient Health Questionnaire 15) digunakan sebagai instrumen pengukur kecenderungan gejala somatisasi. Analisis data dilakukan dengan uji Chi Square dengan tingkat kemaknaan yang digunakan p< 0,05. Pada kategori stres akademik rendah dan sedang dijumpai 33 responden yang mengalami gejala somatisasi dan 13 responden tidak mengalami gejala somatisasi. Sedangkan untuk kategori stres akademik tinggi terdapat 49 responden yang mengalami gejala somatisasi dan 7 responden yang tidak mengalami gejala somatisasi. Hasil uji statistik chi-square menunjukkan bahwa terdapat hubungan bermakna antara stres akademik dan gejala somatisasi pada siswa SMA dalam masa pembelajaran online (p=0,046). Berdasarkan hasil penelitian, terdapat hubungan yang bermakna antara stres akademik dan gejala somatisasi pada siswa SMA dalam masa pembelajaran online. Kata Kunci: Stres akademik, Somatisasi, pandemic covid
Relationship between Emotional Distress and Workplace Influence on Depressive Symptoms among Online Motorcycle Taxi Drivers Merijanti, Lie Tanu; Hairunisa, Nany; Ridwan, Alvin Muhamad; Pusparini, Pusparini; Meiyanti, Meiyanti; Tjahjadi, Muljadi; Isahak, Marzuki bin
Althea Medical Journal Vol 11, No 4 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v11n4.3417

Abstract

Background: The rise of online motorcycle taxi services, driven by the demand for transportation and new technologies, has created a new landscape for drivers. However, despite the benefits, these drivers are not considered employees and are therefore vulnerable to psychosocial risks. This study aimed to investigate the relationship between psychosocial hazards and depressive symptoms among online motorcycle taxi drivers. Methods: A cross-sectional study was conducted, involving 218 online motorcycle taxi drivers in Jakarta, Bogor, Depok, and Tangerang from September to December 2022. The Copenhagen Psychosocial Questionnaire version III was used to assess psychosocial hazards in the workplace and the likelihood of developing depressive symptoms. A multiple linear regression test was used, with a significance level set of p < 0.05.Results: Most respondents were male, and many had worked for over five years, with the majority working more than 8 hours a day. Emotional burden and workplace influences were positively correlated with depressive symptoms (p = 0.017; β = 0.154; and p = 0.002; β = 0.166, respectively). In contrast, the meaning of work and clarity of roles were negatively correlated with depressive symptoms (p = 0.009; β = -0.161; and p = 0.024; β = -0.195, respectively).Conclusion: This study highlights that emotional stress and workplace influence can exacerbate depressive symptoms, while a clear and meaningful work environment have a positive impact. Healthy lifestyle habits are one of the stress management solutions to improve emotional wellness.
Pemakaian Flat Shoes dan Indeks Massa Tubuh Berhubungan dengan Gejala Plantar Fasciitis pada Mahasiswi Trisakti Yulizah, Intania; Merijanti, Lie Tanu
Jurnal Kedokteran Meditek Vol 31 No 2 (2025): MARCH
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i2.3303

Abstract

Introduction: Flat Shoes are shoes that female students often wear. However, the flat model does not provide adequate support for the feet, which increases the risk of plantar fasciitis. Research on plantar fasciitis is more often associated with high heels. In contrast, many women now wear flat shoes daily, most of which are worn by medical students.  Purpose: This research aims to assess the relationship between the duration of flat shoe use and Body Mass Index with the occurrence of plantar fasciitis symptoms in female students. Methods: The design of this study is an observational analytic with a cross-sectional approach, using the consecutive non-random sampling method, the sample size consisted of 162 female respondents from the Faculty of Economics and Business at Trisakti University. Data was collected using a questionnaire to determine the duration of shoe use, the Pain Scale for Plantar Fasciitis questionnaire for plantar fasciitis symptoms, also weight and height measurements to obtain the Body Mass Index value. Data analysis using Chi-Square with a significance level of p<0.05.  Results: The prevalence of plantar fasciitis symptoms was 18.5%.  There was relationship between BMI and the duration of flat shoe use with plantar fasciitis symptoms (p=0.026 and p<0.001). Conclusion: This study concludes a significant relationship between the duration of wearing flat shoes and nutritional status with the symptoms of plantar fasciitis. This research is useful for providing information on risk factors for plantar fasciitis.
Health Extension on Prevention of Anemia for Female Cadres in Krendang Village, West Jakarta Alvina, Alvina; Pusparini, Pusparini; Merijanti, Lie Tanu
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 4 (2025): Volume 8 No 4 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i4.17855

Abstract

ABSTRACT Anemia is one of the conditions that may result in decreased work productivity and low academic achievement, because a person with anemia becomes weak, exhausted, fatigued, and limp, all of which may disturb the person’s concentration in working and learning. There are several factors that can cause anemia, one of which is poor knowledge about the prevention of anemia. Female cadres are expected to assist the government in disseminating the knowledge required in the prevention of anemia. The purpose of this Community Service (Pengabdian Kepada Masyarakat, PKM) is to provide education through health extension on the prevention of anemia to the female cadres of Krendang village (kelurahan), West Jakarta. During the Community Service tests are given before and after the health extension to determine the understanding of the participants about the presented matter. The test results showed an increased understanding after the health extension. Education through health extension was able to increase the understanding and knowledge of the female cadres. Further education of the female cadres is needed such that they become able to disseminate the prevention of anemia to the community. Keywords: Knowledge, Anemia, Female Cadres
Penyuluhan Kenali Tanda dan Gejala Diabetes Melitus Pada Petugas PPSU di Jakarta Barat Pusparini, Pusparini; Mario, Mario; Alvina, Alvina; Merijanti, Lie Tanu; Ferina, Mutiara
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 5 (2025): Volume 8 No 5 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i5.19654

Abstract

ABSTRAK Diabetes mellitus (DM) merupakan penyakit yang mempunyai angka kekerapan tinggi di dunia maupun di Indonesia. Penderita DM sering tidak menyadari dirinya terdampak DM karena gejalanya mirip dengan orang normal pada umumnya.  Gejala DM yang sering ditemukan antara lain sering haus, sering lapar, sering buang air kecil dan penurunan berat badan berlebih. Tanda dan gejala DM yang menyerupai hal yang biasa dijumpai pada orang normal menyebabkan masyarakat awam dapat tidak menyadari bahwa dirinya terdampak DM. Masyarakat awam banyak yang memerlukan edukasi terkait apa itu kencing manis dan bagaimana cara mengenali gejalanya. Salah satu kelompok masyarakat yang perlu mendapat perhatian adalah petugas penanganan prasarana dan sarana umum (PPSU) atau dikenal dengan pasukan oranye. Tujuan program PkM ini adalah agar petugas PPSU dapat mengenali tanda dan gejala DM dan dapat serta mau memeriksakan diri ke Puskemas bila mendapat gejala terkait DM. Pelaksanaan PkM dilakukan dengan penyuluhan dan tanya jawab kepada 69 petugas PPSU di Kelurahan Kedaung Kali Angke, Kecamatan Cengkareng Jakarta Barat.  Hasil penyuluhan menunjukkan terdapat peningkatan pemahaman mengenai tanda dan gejala DM pada petugas PPSU. Diperlukan penyuluhan yang berkelanjutan pada petugas PPSU mengenai penyakit DM sehingga dapat dicegah terjadinya DM dengan perubahan gaya hidup. Kata Kunci: Diabetes Mellitus, PPSU, Sering Kecing, Sering Lapar, Sering Haus  ABSTRACT Diabetes Mellitus (DM) is a disease with a high frequency worldwide and in Indonesia. Patients with DM usually do not realize that they have DM because their symptoms are similar to those of a healthy person. The symptoms of DM that are usually observed include polydipsi,polyphagia, polyuria, and excess weight loss. The signs and symptoms of DM are similar to those of a normal person; therefore, ordinary people cannot realize that they are affected by DM. Ordinary people require education related to DM and knowledge of the signs and symptoms. One of the ordinary people is petugas penanganan prasarana dan sarana umum (PPSU) or are known as orange squad. The goal of this community service is to teach PPSU officers so that they can know the signs and symptoms of DM, so they want to examine the doctor if they have symptoms related to DM. The implementation of PkM was carried out through counseling, questions, and answers to 69 PPSU officers at Kedaung Kali Angke village, Cengkareng District, West Jakarta, show that there is an increase in understanding the signs and symptoms of DM among PPSU officers, and continuous education is needed for PPSU officers regarding DM so that DM can be prevented by changing their lifestyle. Keywords:  Diabetes Mellitus, PPSU, Polyuria, Polyphagi, Polydipsi
Co-Authors Alvina Alvina Alvina Lesmana, Alvina Dewi Hastuty Dian Mediana, Dian Eveline Margo, Eveline Ferina, Mutiara Hairunisa, Nany Isahak, Marzuki bin Joice Viladelphia Kalumpiu Kartini Kurniasari Kurniasari Kurniasari Kurniasari Magdalena Wartono Mario Mario Mario Mario Meiyanti Meiyanti, Meiyanti Novia I. Sudharma, Novia I. Prasetyadi, Indiarto Nindyo Purnamawati Tjhin Pusparini Pusparini Pusparini Pusparini Rahmatullah, Ilham Arief Ridwan, Alvin Muhamad Tjahjadi, Muljadi Widia Aina Rohmah Yulizah, Intania