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All Journal Majalah Kedokteran Bandung ODONTO Dental Journal Dentino: Jurnal Kedokteran Gigi Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Padjadjaran Journal of Dental Researchers and Students Interdental Jurnal Kedokteran Gigi (IJKG) Odonto dental journal
Myrna Nurlatifah Zakaria, Myrna Nurlatifah
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Antibacterial and Antifungal Activities of the Leaf Extracts of Mentha piperita L. Jeffrey, Jeffrey; Nasution, Dewi Lidya Ichwana; Zakaria, Myrna Nurlatifah; Fitriani, Anisa; Junir, Aurorin Silvia
Majalah Kedokteran Bandung Vol 48, No 1 (2026)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v58.4368

Abstract

Herbal medicines are increasingly used due to the presence of bioactive compounds with antibacterial and antifungal properties. This study aimed to evaluate the antibacterial and antifungal effects of Mentha piperita L. extract against Porphyromonas gingivalis and Candida albicans. A laboratory-based experimental study with a post-test only control group design was conducted. The test organisms were exposed to M. piperita L. extract at concentrations of 3.125%, 6.25%, 12.5%, 25%, 50%, and 100%. The antibacterial and antifungal activities were evaluated using the agar well diffusion method to determine inhibition zones, followed by broth dilution tests to identify the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC), and Minimum Fungicidal Concentration (MFC). Statistical analysis was performed using one-way ANOVA with a significance level of p<0.05. Results showed that all concentrations inhibited the growth of both microorganisms, with MIC values of 12.5% and 25% for P. gingivalis and C. albicans, respectively. The MBC for P. gingivalis and MFC for C. albicans were both observed at 100%. There were significant differences (p<0.05) in the inhibition zones across the concentrations tested. In conclusion, Mentha piperita L. extract demonstrates significant antibacterial and antifungal activities against Porphyromonas gingivalis and Candida albicans, suggesting its potential as a natural antimicrobial agent for oral infections.
Co-Authors Ani Melani Maskoen Anne Agustina Suwargiani Artilia, Ira Atia Nurul Sidiqa Badi Soerachman, Badi Cahyanto, Arief Endrowahyudi, Hartanto Fitriani, Anisa Gita Gayatri, Gita I Made Joni Jeffrey ., Jeffrey Junir, Aurorin Silvia Milly Armilia, Milly Moch. Richata Fadil, Moch. Richata Muqdas, Faza Annisa Nasution, Dewi Lidya Ichwana Nursaena, Maysa Pratami, Risa Rajasa, Pahargyan Arya Shariff, Khairul Anuar Suri, Yuyun Andina Suryanto, Shenny Shefira