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All Journal International Journal of Integrated Health Sciences Majalah Kedokteran Bandung Althea Medical Journal Sari Pediatri Majalah Kesehatan FKUB Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Folia Medica Indonesiana
Adhi Kristianto Sugianli
Department Of Clinical Pathology, Faculty Of Medicine, Padjadjaran University/Dr. Hasan Sadikin Hospital, Bandung, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health

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Journal : Althea Medical Journal

 1 
Role of Kletik oil, Ginger and Garlic Extracts towards Soft Tissue Injury Qing Nan, Benjamin Yong; Ismiarto, Yoyos Dias; Sugianli, Adhi Kristianto
Althea Medical Journal Vol 3, No 3 (2016)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (137.926 KB)

Abstract

Background: There is an increased consumption of herbal medicines throughout the world as an alternative treatment for curing health problems. Several herbal medicines are believed to contain anti-inflammatory properties that could trigger healing process. But little is known about the combination effect of herbal medicines. Therefore, the objective of the study was to determine the effects of garlic, ginger and coconut oil (kletik oil) on soft tissue injury (swelling).Methods: The study was held in the research laboratory of Faculty of Medicine Universitas Padjadjaran, from 24th September until 1st October 2014. This experimental study used 7 healthy rabbits (Lepus curpaeums, ±2.5kg) as animal models for each control and intervention group with induced soft tissue injury in the dorsal ear to mimic swelling (inflammation). The mixture of herbs was applied on the injured site in the trial group, while the healing process was denoted by the thickness of edema and time of observation. The data was analyzed using Wilcoxon test.Results: The study results showed that after observation time of 0.5 hour, 2 hours, and 5 hours, edema thickness was unvaried. Onset of action of the herbal mixture began 24 hours after induced injury, with significant difference of edema thickness on both groups; hence the p-value 0.019 (p<0.05).Conclusions: The herbal mixture of ginger, garlic, and coconut oil (kletik oil) contains anti-inflammatory properties to enhance the healing process of soft tissue injury. [AMJ.2016;3(3):421–4]DOI: 10.15850/amj.v3n3.870 
Role of Kletik oil, Ginger and Garlic Extracts towards Soft Tissue Injury Benjamin Yong Qing Nan; Yoyos Dias Ismiarto; Adhi Kristianto Sugianli
Althea Medical Journal Vol 3, No 3 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (57.845 KB)

Abstract

Background: There is an increased consumption of herbal medicines throughout the world as an alternative treatment for curing health problems. Several herbal medicines are believed to contain anti-inflammatory properties that could trigger healing process. But little is known about the combination effect of herbal medicines. Therefore, the objective of the study was to determine the effects of garlic, ginger and coconut oil (kletik oil) on soft tissue injury (swelling).Methods: The study was held in the research laboratory of Faculty of Medicine Universitas Padjadjaran, from 24th September until 1st October 2014. This experimental study used 7 healthy rabbits (Lepus curpaeums, ±2.5kg) as animal models for each control and intervention group with induced soft tissue injury in the dorsal ear to mimic swelling (inflammation). The mixture of herbs was applied on the injured site in the trial group, while the healing process was denoted by the thickness of edema and time of observation. The data was analyzed using Wilcoxon test.Results: The study results showed that after observation time of 0.5 hour, 2 hours, and 5 hours, edema thickness was unvaried. Onset of action of the herbal mixture began 24 hours after induced injury, with significant difference of edema thickness on both groups; hence the p-value 0.019 (p<0.05).Conclusions: The herbal mixture of ginger, garlic, and coconut oil (kletik oil) contains anti-inflammatory properties to enhance the healing process of soft tissue injury. [AMJ.2016;3(3):421–4]DOI: 10.15850/amj.v3n3.870 
Clinical Manifestation and Hematologic Interpretation of Pediatric Systematic Lupus Erythematosus at Initial Presentation: 2-Years Observation Hasti Savira Yudiana; Reni Ghrahani; Adhi Kristianto Sugianli
Althea Medical Journal Vol 8, No 2 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n2.2153

Abstract

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by a spectrum of clinical manifestations, immunological abnormalities, and varied laboratories results. In children, SLE manifestation is particularly more severe, involving more organs. Hematological manifestation has been known as the most common manifestation. The purpose of this study was to describe the clinical manifestations and hematologic interpretation of pediatric SLE at initial presentation.Methods: This retrospective data collection study was conducted at the Department of Child Health Dr. Hasan Sadikin General Hospital Bandung on medical records from a two-year period of 2017–2018. The clinical manifestations were categorized into malar rash, discoid rash, photosensitivity, oral ulcers, arthritis, renal disorders, and neurological disorders. The hematologic interpretations were categorized into anemia, leukopenia, neutropenia, lymphopenia, and thrombocytopenia. Clinical manifestations and hematological interpretations were presented as occurrence percentages and stratified into three age-group of pre-pubertal, peri-pubertal, and post-pubertal.Results: Among 79 pediatric SLE patients (median age 14 years old; IQR 11–16), female gender was predominant. Abnormalities hematologic interpretation occurs in more than half of the patients (83.5%). Malar rash and anemia were the commonest findings among all age groups. Increased occurrence of neuropsychiatric and renal disorders were observed in all age-groups.Conclusions: Malar rash and anemia are important findings among pediatric SLE patients. Furthermore, the occurrences of the neuropsychiatric and renal disorders are also important.
Clinical Manifestations and Laboratory Examination Findings of Hepatocellular Carcinoma at a Tertiary Care Facility in Bandung: An Annual Observation Study Grace Amanda Maharani; Eka Surya Nugraha; Adhi Kristianto Sugianli
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2333

Abstract

Background: Hepatocellular Carcinoma (HCC) is the most prevalent liver cancer with high mortality. Early detection is important for better patient outcomes. The aim of this study was to explore clinical manifestations and laboratory examinations among HCC patients in a tertiary care facility.Methods: This was a cross-sectional descriptive study with a total sampling method, reviewing the medical record of patients with HCC in the Outpatient Clinic of Dr. Hasan Sadikin General Hospital between January to December 2019. Clinical manifestations, laboratory findings, and imaging results data were collected.Results: Of the 112 HCC patients included in this study, the HCC findings among new patients at the outpatient clinic were 8.4%, with hepatitis B (80.8%) as the major etiology. Complaints of abdominal pain (65.2%) was frequent. Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were increased in 89.8% and 67% of patients, as well as total bilirubin levels in 58.8% of patients. In contrast, hemoglobin and albumin levels decreased in 55.3% and 78.1% of patients, respectively. The characteristics of tumor were mainly multinodular, with a size of 3-10 cm.Conclusions: The annual proportion of HCC in Dr. Hasan Sadikin General Hospital in 2019 is 8.4% among all outpatient gastrointestinal and hepatology cases, with hepatitis B as the most common etiology. Abdominal pain is the predominantly prevalent clinical manifestation with increased ALT and AST levels.
Co-Authors Adrian Gunawan, Adrian Adrizain, Riyadi Agus Sunardi Agustinus Wiraatmadja Aini, Endah Nurul Amalia, Ridha Amiliana M. Soesanto Andaru Dahesihdewi Ariel Bagoes Prakoso Audiyananda, Dwika Benjamin Yong Qing Nan Coriejati Rita Delita Prihatni Dewi Kartika Turbawaty Eka Surya Nugraha Emmy Hermiyanti Pranggono Endah Nurul Aini Fatimah Grace Amanda Maharani Hartranti, Yovita Hasti Savira Yudiana Hermawan Nagar Rasyid, Hermawan Nagar Horian, Erinca Ida Parwati Ida Parwati Ida Parwati Jennifer Hadiman Juandika Juandika Kasih Pasaribu, Elisabeth Putri Kwarteng, Alexander Leni Lismayanti Lilik Indrawati, Lilik Mia Milanti Dewi Nadjwa Zamalek Dalimoenthe Nina Tristina Nita Elvina Wisudawati Nur Suryawan Hidayat Prakoso, Baskoro Justicia Pranggono, Emmy Hermiyanti Prihatni, Delita Qing Nan, Benjamin Yong Raja Iqbal Mulya Harahap Rarsari Soerarso Reni Ghrahani Ronal Winter Shofia Widya Murti Siti Aminah Surata, Nida Susi Susanah Trie Utami, Fadila Dyah Uun Sumardi, Uun Yovita Hartranti Yoyos Dias Ismiarto