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All Journal International Journal of Integrated Health Sciences Majalah Kedokteran Bandung Althea Medical Journal Indonesian Journal of Rheumatology Majalah Kedokteran Neurosains Medica Hospitalia Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Anna Tjandrawati
Department Of Clinical Pathology, Faculty Of Medicine, Padjadjaran University/Dr. Hasan Hasan Sadikin Hospital, Bandung
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Two Years Profile of Anemia in Systemic Lupus Erythematosus Patients at West Java’s Top Referral Hospital, Indonesia Usman, Stefanie Yuliana; Hamijoyo, Laniyati; Tjandrawati, Anna
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (182.897 KB) | DOI: 10.15850/amj.v4n2.1094

Abstract

Background: Anemia is a common clinical manifestation in Systemic Lupus Erythematosus (SLE) patients. Anemia can be caused by an ineffective hematopoietic process or excessive red blood cell destruction. The aim of this study was to classify and characterize anemia in SLE patients.Methods: This study involved 97 outpatients visiting the Rheumatology Clinic of Dr. Hasan Sadikin General Hospital Bandung, from January 2013 to September 2014. Patient data was collected from medical records and study subjects were selected according to the American College of Rheumatology 1997 criteria for SLE, and the characteristic of anemia among outpatients were described according to the World Health Organization criteria.Results: The characteristics among 97 respondents showed 95 (98%) were female; 32 (33%) were 21–30 years old; and 49 (51%) had SLE for 1–5 years. The characteristics and classification of anemia, 57 (59%) had normocytic normochromic, and 33 (34%) had microcytic hypochromic anemia. According to the severity classification, 48 (50 %) had moderate anemia, only 8 (8%) had severe anemia. Four (4%) subjects had anemic conjunctiva, 45 (46%) had fatigue and 48 (50%) had no clinical manifestations of anemic conjunctiva and fatigue.Conclusions: Moderate anemia, normocytic normochromic anemia are the most prevalent among the subjects. Half of the anemic SLE patient has no clinical manifestation of anemic conjunctiva and fatigue.DOI: 10.15850/amj.v4n2.1094
Characteristics of Asthma Patients Seeking Care at West Java’s Top Referral Hospital, Indonesia Yudistira, Juan Achmad; Pranggono, Emmy Hermiyanti; Tjandrawati, Anna; Sudjana, Primal
Althea Medical Journal Vol 4, No 1 (2017)
Publisher : Althea Medical Journal

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Abstract

Background: The increasing incidence of asthma in many countries in recent decades makes asthma a global health problem. The aim of the study was to determine the characteristics of asthma patients at the Respirology Outpatient Clinic of Dr. Hasan Sadikin General Hospital as West Java’s Top referral hospital. Methods: The study used a cross-sectional design. The study population was the medical record data of asthma patients at the Respirology Outpatient Clinic during June 2012–June 2013. There were 1,591 patient’s medical records at the Respirology Outpatient Clinic of Dr. Hasan Sadikin General Hospital Bandung in that period and 140 medical records were diagnosed with asthma. Seventy medical records were excluded because of inadequate data and 70 medical records were the sample of this study. The collected data were presented using percentage. Results: Seventy percent of the cases were female. From these cases 34% of patients   were aged 51–60 years. The partially controlled type was the most frequent type of asthma (62%). The most common sign and symptom was shortness of breath (86%). The most common drug used was Beta 2 agonist drugs (90%).Conclusions: The characteristic of asthma is that the patients are mostly female. Mostly the patients were in the age range of 51–60 years. The partially controlled type is the most frequent type of asthma. Shortness of breath is the most common clinical manifestation in asthma. Beta 2 agonist is the most used drug for asthma. [AMJ.2017;4(1):78–82]DOI: 10.15850/amj.v4n1.1025
HUBUNGAN ANTARA KADAR 8HYDROXY2DEOXYGUANOSINE SERUM DENGAN FUNGSI KOGNITIF PADA STROKE ISKEMIK Alya Tursina , Andi Basuki Prima Birawa, Dede Gunawan, Anna Tjandrawati
NEURONA Vol 32 No. 2 Maret 2015
Publisher : Neurona Majalah Kedokteran Neuro Sains

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Abstract

INTRODUCTION POSTSTROKE DISABILITIES ATTRIBUTED TO PHYSICAL DISORDERS CAN BE WORSENED BY THE PRESENCE OF COGNITIVE DYSFUNCTION SERUM 8HYDROXY2DEOXYGUANOSINE 8OHDG IS THE RESULT OF FREE RADICAL INTERACTION WITH THE C8 GROUP OF GUANINE BASE INCREASED SERUM 8OHDG CONCENTRATION INDICATES NEURONAL DAMAGE AND AFFECTS COGNITIVE FUNCTION IN ISCHEMIC STROKE PATIENTS EXAMINED USING MONTREAL COGNITIVE ASSESSMENTINDONESIA VERSION MOCAINA
VALIDITAS PEMERIKSAAN COMPLEX SPECIFIC ANTIGEN MYCOBACTERIUM TUBERCULOSIS REGION OF DIFFERENCE 1‒3 METODE RAPID IMMUNOCHROMATOGRAPHY PADA SPUTUM PENDERITA TUBERKULOSIS PARU Gustiani, Nenny; Parwati, Ida; Tjandrawati, Anna; Lismayanti, Leni
Majalah Kedokteran Bandung Vol 46, No 4 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Tuberkulosis (TB) paru merupakan masalah kesehatan global. Diagnosis tuberkulosis paru saat ini berdasarkan pemeriksaan mikroskopis basil tahan asam (BTA) pada sputum dengan pewarnaan Ziehl Nelseen, namun sensitivitasnya rendah. Pemeriksaan antigen TB metode rapid immunochromatography (ICT) adalah suatu tes yang cepat, mudah, praktis, dan tidak memerlukan keterampilan khusus. Tes ini mendeteksi antigen yang disekresi Mycobacterium tuberculosis yaitu early secretory antigenic target 6 kDa protein (ESAT6), culture filtrate protein (CFP10), dan Mycobacterium protein tuberculosis (MPT64) yang disandi oleh gen region of difference (RD)1, RD2, dan RD3. Tujuan penelitian untuk mengetahui validitas antigen TB ICT dalam mendiagnosis tuberkulosis paru. Penelitian dilaksanakan September 2012?Maret 2013 di Rumah Sakit Dr. Hasan Sadikin Bandung. Bentuk penelitian adalah observasional deskriptif dengan rancangan penelitian potong lintang dan analisis uji diagnostik. Setiap spesimen sputum dilakukan pemeriksaan mikroskopis BTA dan antigen TB rapid ICT. Biakan M. tuberculosis pada medium Ogawa digunakan sebagai standar baku emas. Tes niasin dilakukan pada koloni yang tumbuh. Didapatkan 149 subjek penelitian, kelompok usia terbanyak pada usia 30?39 tahun. Hasil pemeriksaan biakan didapatkan 56 sampel tumbuh, 86 tidak tumbuh, dan 7 terkontaminasi. Sensitivitas dan spesifisitas pemeriksaan antigen TB rapid ICT masing masing adalah 95,7% dan 87,2%. Simpulan, pemeriksaan antigen TB rapid ICT mempunyai validitas yang tinggi, sehingga dapat digunakan sebagai alternatif pemeriksaan laboratorium untuk diagnosis TB paru. Kata kunci: Antigen TB rapid ICT, biakan M. tuberculosis, medium Ogawa, mikroskopis BTAValidity of Complex Specific Antigen Mycobacterium Tuberculosis Region of Difference 1?3 Examination Using Rapid Immunochromatography Method in Pulmonary Tuberculosis Patient Sputum AbstractPulmonary tuberculosis (TB) is still a global health problem. The diagnosis of pulmonary tuberculosis is based on sputum smear microscopy for acid fast bacilli (AFB) using Ziehl-Neelsen staining. However, this method has low sensitivity. Tuberculosis antigen immunochromatographyrapid test (ICT) is a quick, easy, and practical test which does not require special skills. This test is used to detect the antigen secretion of early secretory antigenic target 6 kDa protein (ESAT6), culture filtrate protein (CFP10)and Mycobacterium protein tuberculosis (MPT64) from Mycobacterium tuberculosis which are encoded by the region of difference (RD) 1, RD2 and RD3 genes. The aim of this study was to determine the validity of TB antigen for the diagnosis of pulmonary tuberculosis. The study was conducted during the period of September 2012 to March 2013 in Dr. Hasan Sadikin General Hospital (RSHS) Bandung. This study is a descriptive observational study using cross sectional approach and validity analysis. From September 2012 until March 2013 there were 149 subjects, in which the dominant age group was 30?39 years. All the specimens were cultured on Ogawa medium as the gold standard and niasin tests were performed on all positive cultures. The TB antigen rapid ICT and sputum smear microscopy AFB were done on all the samples. From 149 subjects, 56 were positive, 86 were negative and 7 were contaminated. The sensitivity and specificity of TB antigen rapid ICT were 95.7% and 87.2%, respectively. In conclusion, TB antigen rapid ICT has a high validity which can be used as alternative laboratory tests for screening in patients with suspected pulmonary tuberculosis.Key words: AFB smear, M. tuberculosis culture, Ogawa medium, TB antigen rapid ICT DOI: 10.15395/mkb.v46n4.344
Kadar Interleukin-6 Serum pada Karsinoma Payudara Lanjut Lokal dan yang Bermetastasis Sapari, Toha; Abdurahman, Maman; Tjandrawati, Anna
Majalah Kedokteran Bandung Vol 46, No 1 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Karsinoma payudara merupakan kanker pada wanita dengan frekuensi tertinggi di dunia dan merupakan penyebab kematian utama. Pasien karsinoma payudara mengalami periode stres fisik dan emosional yang mendorong diproduksinya protein seperti interleukin-6 (IL-6). Interleukin-6 berperan penting dalam tumorigenesis karsinoma payudara melalui aktivasi jalur janus kinase (JAK). Penelitian ini mengukur kadar IL-6 serum yang berperan penting pada patogenesis molekuler proses metastasis pada karsinoma payudara lanjut lokal (KPLL) dibandingkan dengan karsinoma payudara bermetastasis (KPM). Rancangan penelitian adalah potong lintang, analitik komparatif dengan membandingkan kadar IL-6 serum rata-rata pada kedua kelompok KPLL dan KPM. Penelitian dilakukan di Rumah Sakit Dr. Hasan Sadikin Bandung (RSHS) dari Juni–November 2012. Subjek penelitian adalah 35 pasien yang terdiri atas 18 KPLL dan 17 KPM. Kadar IL-6 diukur dengan teknik pemeriksaan enzyme-linked immunosorbent assay (ELISA). Hasil yang diperoleh dari penelitian ini kadar IL-6 serum rata-rata pada KPLL 4,99 pg/mL dan kadar IL-6 serum pada KPM 32,73 pg/mL. Terdapat perbedaan bermakna kadar IL-6 serum antara KPLL dan KPM, p<0,01. Hasil analisis dengan uji chi-kuadrat pada derajat kepercayaan 95%, bahwa terdapat hubungan kadar IL-6 serum dengan kejadian metastasis. Subjek dengan kadar IL-6 serum >9,85 pg/mL memiliki risiko kejadian metastasis 37,5 kali dibandingkan dengan kadar IL-6 serum ≤9,85 pg/mL. Simpulan, kadar IL-6 serum pada KPM lebih tinggi dibandingkan dengan KPLL. [MKB. 2014;46(1):15–21]Kata kunci: Interleukin-6, KPLL, KPMSerum Interleukin-6 Levels in Locally Advanced and Metastatic Breast CancerBreast carcinoma is a cancer in women with the highest frequency in the world and is the leading cause of death. Patients with breast carcinoma experience periods of stress both physical and emotional which encourages them to produce proteins such as interleukin-6 (IL-6). Interleukin-6 plays an important role in tumorigenesis via activation of janus activated kinase (JAK). This study measured the levels of serum IL-6 which plays an important role in the molecular pathogenesis of metastasis in locally advanced breast cancer (LABC) compared to metastatic breast cancer (MBC). The study design was cross-sectional, comparative analytics by comparing the mean levels of IL-6 in both groups: LABC and MBC. The study was conducted at the Dr. Hasan Sadikin Hospital Bandung (RSHS) from June–November 2012. Subjects were 35 women consisting of 18 LABC and 17 MBC. Levels of serum IL-6 were measured by enzyme-linked immunosorbent assay (ELISA) technique. The results of this study show that the mean levels of serum IL-6 on LABC 4.99 pg/mL and the mean levels of serum IL-6 on MBC 32.73 pg/mL. There was a significant difference between the levels of serum IL-6 on LABC and MBC, p<0.01. Results of the analysis with chi-square test shows there is a correlation between level of IL-6 with metastasis incidence. Subjects with levels of serum IL-6>9.85 pg/mL had 37,5 times higher risk for incidence of metastasis. In conclusion, the levels of serum IL-6 on MBCare higher than LABC. [MKB. 2014;46(1):15–21]Key words: Interleukin-6, LABC, MBC DOI: 10.15395/mkb.v46n1.222
Validitas Multiplex Real Time Polymerase Chain Reaction untuk Diagnosis Limfadenitis Tuberkulosis pada Spesimen Blok Parafin Rezeki, Mike; Parwati, Ida; Hernowo, Bethy S.; Tjandrawati, Anna
Majalah Kedokteran Bandung Vol 46, No 3 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Limfadenitis tuberkulosis merupakan tuberkulosis ekstraparu yang paling sering ditemukan. Saat ini baku emas diagnosis limfadenitis tuberkulosis berdasarkan histopatologi. Pemeriksaan histopatologi tidak memberikan informasi etiologi pasti penyebab limfadenitis, padahal limfadenitis dapat disebabkan Mycobacterium tuberculosis maupun Mycobacterium non-tuberculosis yang sangat berbeda regimen terapinya. Spesimen limfadenitis tuberkulosis dalam blok parafin yang disimpan sangat bermanfaat ketika dibutuhkan pemeriksaan lanjutan.  Pemeriksaan multiplex real time polymerase chain reaction  pada  blok parafin dapat mendeteksi Mycobacterium  tuberculosis atau Mycobacterium  non-tuberculosis. Pemilihan objek penelitian dilakukan berdasarkan randomisasi sederhana. Penelitian uji diagnostik dengan  rancangan potong lintang untuk mengetahui  validitas pemeriksaan multiplex  real time polymerase chain reaction  dalam  mendiagnosis limfadenitis tuberkulosis  sebagai konfirmasi pada blok parafin dilakukan periode Juni 2012˗˗Juni 2013 di Rumah Sakit Dr. Hasan Sadikin Bandung. Objek penelitian terdiri atas 40 blok parafin limfadenitis tuberkulosis dan 22 blok parafin kelompok kontrol. Pemeriksaan multiplex real time poymerase chain reaction menggunakan primer gen sikuens sisipan IS6110 dan gen Mycobacterium protein tuberkulosis MPB64 untuk mendeteksi deoxyribonucleic acid Mycobacterium tuberculosis dan gen 16S rRNA (ribosomal ribonucleic acid) untuk mendeteksi Mycobacterium non-tuberculosis. Hasil uji validitas sensitivitas 75%, spesifisitas 77%, nilai duga positif 86,6%, nilai duga negatif 63%, dan akurasi 75,8%. Pemeriksaan multiplex real time polymerase chain reaction dapat dianjurkan untuk konfirmasi diagnosis limfadenitis tuberkulosis pada blok parafin. Simpulan: multiplex real time polymerase chain reaction  memiliki validitas sedang untuk diagnosis limfadenitis tuberkulosis pada spesimen blok parafin.Kata kunci: Deoxyribonucleic acid, limfadenitis tuberkulosis, multiplex real time polymerase chain reaction, Mycobacterium tuberculosis Validity of Multiplex Real Time Polymerase Chain Reaction for Tuberculous Lymphadenitis Diagnosis on Formalin Fixed Paraffin EmbeddedTuberculous lymphadenitis is one of the most common form of extra pulmonary tuberculous. The diagnosis of tuberculous lymphadenitis based  on  histopathology as a gold standard. Histopathology examination could not inform the etiology of lymphadenitis whether Mycobacterium tuberculosis or Mycobacterium nontuberculosis  of which  the treatment regiment is very different. The archieved specimen like formalin fixed paraffin embedded  of tuberculous lymphadenitis is useful for futher investigation. The multiplex real time polymerase chain reaction  can detect  Mycobacterium tuberculosis or Mycobacterium nontuberculosis  from formalin fixed paraffin embedded. The object of the study use simple random. The study with cross sectional design  to determine validity multiplex real time polymerase chain reaction  on tuberculous lymphadenitis from formalin fixed paraffin embedded, was done June 2012˗˗June 2013 at Dr. Hasan Sadikin Hospital Bandung. Objects  consisted  of  40  formalin fixed paraffin embedded  tuberculous lymphadenitis and  22 control group. The multiplex real time polymerase chain reaction use insertion  sequence IS6110 and Mycobacterium protein tuberculosis MPB64 gen for detect deoxyribonucleic acid Mycobacterium tuberculosis and 16S rRNA (ribosomal ribonucleic acid) gen for Mycobacterium nontuberculosis. The validity test of the Mycobacterium tuberculosis multiplex real time polymerase chain reaction with histopathology as a gold standards gave a sensitivity 75%, specificity 77%, positive predictive value 86.6%, negative predictive value 63%, and accuracy 75.8%. This examination can be used for confirmation of tuberculous lymphadenitis from formalin fixed paraffin embedded. Conclussion: multiplex real time polymerase chain reaction has intermediate validity to diagnose tuberculous lymphadentis on formalin fixed paraffin embedded.Key words: Deoxyribonucleic acid,  multiplex real time polymerase chain reaction, Mycobacterium tuberculosis DOI: 10.15395/mkb.v46n3.314
IP-10 as a Non Sputum Biomarker in TB Treatment Monitoring Efriyani, Yuhpita Indah; Parwati, Ida; Tristina, Nina; Tjandrawati, Anna
Majalah Kedokteran Bandung Vol 53, No 1 (2021)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v53n1.2161

Abstract

There are currently still limitations in the diagnosis of tuberculosis (TB). Sputum collection as specimen for diagnosis is not only difficult but also has low sensitivity.In blood, IP-10/CXCL-10 chemokine plays a role in inducing the movements of chemotactic inflammatory cells towards the sites of inflammation. A high level of IP-10 is found in active pulmonary TB patients and significantly decline after the patients have completed the TB treatments. The aim of this study was to analyze the decline of the IP-10 level before and after 2 months of TB treatment. This study was conducted from March­ toJuni 2020. This was a comparative observational cohort study on active pulmonary TB patients who were >18 years old at the DOTS Clinic of Dr. Hasan Sadikin General Hospital Bandung. Thirty patients who met the inclusion criteria were followed up until 2 months of TB treatment. Serum of  these patients were collected and examined for the IP-10 level before and after 2 months of TB treatment. It was demonstrated that the median IP-10 level in new active pulmonary TB patients was 384.1 pg/mL (136.70–779.80) and dropped to 251.85 pg/mL (91.10–698.30) (p<0l001) two months of TB treatment. Thus, the IP-10 level in the active pulmonary TB patients is significantly declined (p<0.001) after 2 months of TB treatment and that serum IP-10 level could be considered as a non-sputum-based marker to monitor TB treatment.
Two Years Profile of Anemia in Systemic Lupus Erythematosus Patients at West Java’s Top Referral Hospital, Indonesia Stefanie Yuliana Usman; Laniyati Hamijoyo; Anna Tjandrawati
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (178.688 KB) | DOI: 10.15850/amj.v4n2.1094

Abstract

Background: Anemia is a common clinical manifestation in Systemic Lupus Erythematosus (SLE) patients. Anemia can be caused by an ineffective hematopoietic process or excessive red blood cell destruction. The aim of this study was to classify and characterize anemia in SLE patients.Methods: This study involved 97 outpatients visiting the Rheumatology Clinic of Dr. Hasan Sadikin General Hospital Bandung, from January 2013 to September 2014. Patient data was collected from medical records and study subjects were selected according to the American College of Rheumatology 1997 criteria for SLE, and the characteristic of anemia among outpatients were described according to the World Health Organization criteria.Results: The characteristics among 97 respondents showed 95 (98%) were female; 32 (33%) were 21–30 years old; and 49 (51%) had SLE for 1–5 years. The characteristics and classification of anemia, 57 (59%) had normocytic normochromic, and 33 (34%) had microcytic hypochromic anemia. According to the severity classification, 48 (50 %) had moderate anemia, only 8 (8%) had severe anemia. Four (4%) subjects had anemic conjunctiva, 45 (46%) had fatigue and 48 (50%) had no clinical manifestations of anemic conjunctiva and fatigue.Conclusions: Moderate anemia, normocytic normochromic anemia are the most prevalent among the subjects. Half of the anemic SLE patient has no clinical manifestation of anemic conjunctiva and fatigue.DOI: 10.15850/amj.v4n2.1094
Characteristics of Asthma Patients Seeking Care at West Java’s Top Referral Hospital, Indonesia Juan Achmad Yudistira; Emmy Hermiyanti Pranggono; Anna Tjandrawati; Primal Sudjana
Althea Medical Journal Vol 4, No 1 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (541.508 KB)

Abstract

Background: The increasing incidence of asthma in many countries in recent decades makes asthma a global health problem. The aim of the study was to determine the characteristics of asthma patients at the Respirology Outpatient Clinic of Dr. Hasan Sadikin General Hospital as West Java’s Top referral hospital. Methods: The study used a cross-sectional design. The study population was the medical record data of asthma patients at the Respirology Outpatient Clinic during June 2012–June 2013. There were 1,591 patient’s medical records at the Respirology Outpatient Clinic of Dr. Hasan Sadikin General Hospital Bandung in that period and 140 medical records were diagnosed with asthma. Seventy medical records were excluded because of inadequate data and 70 medical records were the sample of this study. The collected data were presented using percentage. Results: Seventy percent of the cases were female. From these cases 34% of patients   were aged 51–60 years. The partially controlled type was the most frequent type of asthma (62%). The most common sign and symptom was shortness of breath (86%). The most common drug used was Beta 2 agonist drugs (90%).Conclusions: The characteristic of asthma is that the patients are mostly female. Mostly the patients were in the age range of 51–60 years. The partially controlled type is the most frequent type of asthma. Shortness of breath is the most common clinical manifestation in asthma. Beta 2 agonist is the most used drug for asthma. [AMJ.2017;4(1):78–82]DOI: 10.15850/amj.v4n1.1025
Methicillin-Resistant Staphylococcus aureus (MRSA) Patterns and Antibiotic Susceptibility in Surgical and Non-Surgical Patients in a Tertiary Hospital in Indonesia Dewi Kartika Turbawaty; Verina Logito; Anna Tjandrawati
Majalah Kedokteran Bandung Vol 53, No 3 (2021)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v53n3.2396

Abstract

Methicillin-Resistant Staphylococcus aureus (MRSA) in the hospital is found mainly in surgical patients, which increases morbidity and mortality. Currently, vancomycin is the drug of choice for the treatment of MRSA infections. The increasing use of vancomycin and its inappropriate administration may increase the resistance of S. aureus to vancomycin. This study aimed to describe the distribution of MRSA and types of antibiotics that are still sensitive to MRSA in surgical and non-surgical patients. This cross-sectional, observational, retrospective descriptive study was conducted at the Microbiology Laboratory, Dr. Hasan Sadikin General Hospital, in 2019 using secondary data on the results of culture examination and antibiotic susceptibility of positive S. aureus culture isolates from all types of isolates from surgical and non-surgical patients. All specimens were cultured in appropriate media. Identification of S. aureus was performed by Gram staining to identify bacterial morphology, and automatic tools. Antibiotic susceptibility test was performed using an automatic machine. Seventy-five isolates (17%) were identified to be MRSA with 46 (53%) of them retrieved from surgical patients. Most of the MRSA isolates came from pus and were mostly due to skin infections. Antibiotic susceptibility results showed two Vancomycin-Resistant Staphylococcus aureus (VRSA) isolates from surgical patients. The positive culture of the MRSA and VRSA was dominated by surgical patients with pus coming from surgical wound infection, burn, and other skin infection as the most common sources. Thus, the proportion of MRSA isolates in the hospital in 2019 is 17% and two VRSA isolates are identified in the same year. The surgical ward was the primary origin of most MRSA isolates. Further studies are necessary to identify the MRSA incidence rate, evaluation and periodic monitoring of antibiotic use, and active surveillance in the surgical patient rooms.
Co-Authors Bethy S. Hernowo Chakrawati Hayuningsih Coriejati Rita Dewi Kartika T Dewi Kartika Turbawaty Dolvy Girawan Efriyani, Yuhpita Indah Elsa Yulius Emmy Hermiyanti Pranggono Erna Jupri Hartanto Bayuaji Haryono Haryono Ida Parwati Ivana Dewi Ivana Dewi Juan Achmad Yudistira Kurnia Pramono, Laila Laniyati Hamijoyo, Laniyati Latifah, Armina Leni Lismayanti Leni Lismayanti Lidya Chaidir Linda Choerunnisa Maman Abdurahman Maria Enrica Mike Rezeki Muhammad Begawan Bestari Nadjwa Zamalek Dalimoenthe Nadjwa Zamalek Dalimoenthe Nenny Agustanti Nenny Gustiani Nida Suraya Nida Suraya Nida Suraya Nina Tristina Primal Sudjana Putri Vidyaniati Rachmat Gunadi Wachjudi Rachmat Gunadi Wachjudi Raja Iqbal Mulya Harahap Rizki Dumpatna Siti Aminah Abdurachman Stefanie Yuliana Usman Sumartini Dewi Sylvia Rachmayati Tiene Rostini, Tiene Toha Sapari Usman, Stefanie Yuliana Verina Logito Verina Logito Winda Agnestia Maranna Saragih Yudi Wahyudi Yudistira, Juan Achmad