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All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) Indonesian Journal of Obstetrics & Gynecology Science Bioscientia Medicina : Journal of Biomedicine and Translational Research Andalas obstetrics and gynecology journal Indonesian Journal of Global Health research Nusantara Science and Technology Proceedings Bioscientia Medicina : Journal of Biomedicine and Translational Research Malahayati International Journal of Nursing and Health Science
Fakhrizal, Edy
Department Of Obstetrics And Gynecology, Faculty Of Medicine, Universitas Riau, Pekanbaru
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Infeksi Saluran Kemih pada Kehamilan: Prevalensi dan Faktor-Faktor yang Memengaruhinya Edy Fakhrizal
Jurnal Ilmu Kedokteran Vol 11, No 1 (2017): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (66.812 KB) | DOI: 10.26891/JIK.v11i1.2017.19-24

Abstract

To obtain a prevalence of urinary tract infection in pregnancy andits influential risk factors.This is a cross sectionalstudy. The subjects were all pregnant women who came to Obstetric & Gynecology clinic of Arifin Achmad Pekanbaru– Riau Hospital, between June 1st and October 31st 2016. Subjects with appropriate inclusion and exclusion criteriaand agreed to join this study were asked to fill out questionnaire and urinalysis test was done.The data was analyzedwith Stata 12. The distribution of data was analyzed with descriptive univariate and presented in (n) and(%). Bivariateanalysis was done to see any influential risk factors to urinary tract infection in pregnancy. From recruited 74 subjects,27subjects (36,5%) were with urinary tract infection and 4 subject of its (14,8%) was asymptomatic bacteriuria. Theprevalence of urinary tract infection in pregnancy in this study was 36,5% and the influential risk factors wereeducation, occupation, total water consumpted a day, and cleaning vagina before coitus.
Inkontinensia Urin Pascapersalinan dan Faktor-Faktor Risiko yang Memengaruhinya Edy Fakhrizal; Sri Wahyu Maryuni
Jurnal Ilmu Kedokteran Vol 10, No 2 (2016): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (61.268 KB) | DOI: 10.26891/JIK.v10i2.2016.98-105

Abstract

Postpartum urinary incontinence is an important and often overlooked form of maternal morbidity. The aim of thisstudy is to obtain prevalence of postpartum urinary incontinence and its influential risk factors. This is an observationalstudy. The subjects were all primipara stayed in Obstetric & Gynecology of Arifin Achmad Pekanbaru – Riau hospital,between July 1st and December 31st 2014. The data of risk factors (demographic and obstetric) was obtained frommedical records and cough test was done too. The data was analyzed with computerized statistic data analysis 12 (Stata 12 ). The distribution of data were analyzed with descriptive univariate and presented in (n) and (%). Bivariateanalysis was done to see any influential risk factors to postpartum urinary incontinence event. The prevalence ofurinary incontinence in this study was 30% and the influential risk factors were BMI, body weight changing duringpregnancy, delivery mode, birthweight and length of second stage.
The Prevalence of Stress Urinary Incontinence in Coastal Community from Riau Province Edy Fakhrizal; Ruza Prima Rustam; Sri Wahyu Maryuni
Nusantara Science and Technology Proceedings 4th Riau Medical Scientific and Expo 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2823

Abstract

Stress Urinary Incontinence (SUI) significantly affects women’s quality of life through physical and psychosocial limitations and sexual dysfunction. This condition may cause a huge individual and family burden, leading to a global burden. The coastal area is geographically located in islands confined by the sea, thus becoming the basis of health problems due to its limited access to healthcare facilities. No study has been conducted to identify the SUI prevalence rate. This study aims to help determine problems caused by SUI, eventually conceiving effective prevention and treatment strategies to be proposed to health policymakers. This research is a quantitative study with women of reproductive age (20 – 44 years old) and >44 years old in 4 coastal areas (Bengkalis, Dumai, Siak, and Rumbai Pesisir) as the key population. Of 320 patients, 178 (53,80%) were screened for urinary incontinence. Among 178 screened subjects, 152 (85%) were classified as stress urinary incontinence, with the highest incidence rate found at Dumai, with 59 (39%) cases. Bengkalis, Siak, and Pekanbaru had an incidence rate of 51 (33%), 33 (22%), and 9 (6%), consequently. This study found most women had urinary incontinence, with the most common type being stress urinary incontinence. Based on this study, due to the high prevalence of SUI, the authors agreed that effective prevention and treatment strategies are needed to prevent SUI's severity and further development.
The Prevalence of Pelvic Organ Prolapse in Coastal Community from Riau Province Edy Fakhrizal; Ruza Prima Rustam; Sri Wahyu Maryuni
Nusantara Science and Technology Proceedings 4th Riau Medical Scientific and Expo 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2824

Abstract

A woman’s quality of life is determined by their physical, psychosocial, and sexual function. These functions are impaired with pelvic organ prolapse (POP), causing a vast burden, individually and globally. With its geographic location, the coastal community may have difficulties in seeking medical attention as the health care facilities provided are limited. To date, no study has been conducted to identify the POP prevalence rate among the coastal community of Riau Province as one of the coastal areas in Indonesia. This study aims to help in determining problems caused by POP, eventually designing effective prevention and treatment strategies to be proposed to health policymakers. This is a quantitative study with all reproductive ages (20 – 44 years old) and >44 years old women in 4 coastal areas in Riau Province (Bengkalis, Dumai, Siak, and Pekanbaru) as the key population. The validated Pelvic Floor Distress Inventory (PFDI) questionnaire in Bahasa Indonesia is used to assess the POP prevalence rate. Out of 343 participants, 204 (63,75%) had POP. The highest POP incidence rate was found in Bengkalis, with a total of 61 (30%) participants with POP. Dumai, Siak, and Pekanbaru had the incidence rate of 59 (29%), 59 (29%), and 25 (12%) consequently. Based on this study, due to the high prevalence of POP, the authors agreed that effective prevention and treatment strategies are needed to prevent the severity and further development of POP.
A Sexual Dysfunction And Quality Of Life Problems Caused By Perineal Pain Cicatrix In A Woman: A Case Report Edy Fakhrizal; M. Lingga Primananda
Andalas Obstetrics And Gynecology Journal Vol. 7 No. 1 (2023)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.7.1.338-341.2023

Abstract

Introduction: Sexual dysfunction is a complaint that could happened because of disturbance in complex processwhich coordinated by neurology system, vascular and endocrine system.1 One cause of sexual disfunction isdyspareunia which also followed by quality of life problems. Problems of dyspareunia, sexual dysfunction andquality of life can be measure with VAS, FSFI and WHOQOL instruments. VAS, Visual Analogue Scale, is one ofthe pain rating scales used in epidemiologic and clinical research to measure the intensity or frequency of varioussymptoms.2 FSFI, Female Sexual Function Index, is a multidimensional questionnaire that can show female sexualfunction. This questionnaire consists of 6 domains in which sexual desire, sexual arousal, lubrication, orgasm,sexual satisfaction and pain.3,4,5 WHOQOL-BREF, World Health Organization Quality-of-Life Scale, is a qualityof life assessment developed by the WHOQOL Group with fifteen international field centres, simultaneously, inan attempt to develop a quality of life assessment that would be applicated by cross-culturally.Case Report : Patient came with complaint of pain in genital opening and perineum that felt since 5 months ago.Patient also came with complaint of dyspareunia. Patient had history of vaginal delivery which causing her aperineal rupture. For 5 months, patient could not get intercourse and made her desperated and suffered becauseof her husband desire. Patient also felt inferiority and these problems disturbed her daily activity. VAS was 8,FSFI was 3, and WHOQOL was 71. The perinel ruptured was sutured at the moment of delivery, but after 1 weekpatient started to felt pain at her birth canal. It was the first pregnancy, delivery process was without anyproblems, baby born with 2900 gram of birth weight. From gynecology examination, found a cicatrix at 5 o’clockdirection, any other gynecology organs within normal limit. Diagnose was dyspareunia ec perineal cicatrix withsexual dysfunction and quality of life problems, then urogynecologist decided to do surgery
Current Evidence of Platelet-Rich Blood Plasma for Pelvic Organ Prolapse: A Review Fakhrizal, Edy; Simanjuntak, Arya Marganda; Hutapea, Anastasya
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 3 November 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v6i3.530

Abstract

Objective: To review the current evidence of the potential use of Platelet-Rich Plasma (PRP) in the field of urogynecology, especially in POP cases.Method: This review used several databases (Google Scholar, Pubmed, and Science Direct) and searched for English and Indonesian articles in the last ten years. Articles were received in the form of case reports, observational studies and clinical trials that discussed the use of Platelet-Rich Plasma in cases of Pelvic Organ Prolapse (POP).Results: A total of three articles were included in this review.Discussion: There were two patient studies and one in vitro study. The POP patient study showed favorable results with low recurrence rates in patients who received Platelet Rich-Plasma compared to those who did not and another study that conducted a one-year evaluation found no recurrences after the patients received Platelet Rich Plasma at the surgical site. The in vitro study showed good cell attachment and proliferation in vaginal tissue biopsies with Platelet-Rich Plasma applied to the tissue.Conclusion: Platelet-Rich Plasma may promote tissue regeneration, hence potentially reduce recurrency after reconstruction.Bukti Terkini Plasma Darah Kaya Trombosit untuk Prolaps Organ Panggul: Sebuah KajianTujuan: Untuk meninjau bukti terkini mengenai potensi penggunaan Platelet-Rich    Plasma di bidang uroginekologi, khususnya pada kasus POP.Metode:Tinjauan ini menggunakan beberapa database Google Scholar, Pubmed, dan Science Direct) dan mencari artikel berbahasa Inggris dan Indonesia dalam sepuluh tahun terakhir. Artikel yang diterima berupa laporan kasus, studi observasional, dan uji klinis yang membahas penggunaan Platelet-Rich Plasma pada kasus Prolaps Organ Panggul (POP).Hasil: Sebanyak tiga artikel termasuk dalam tinjauan ini.Diskusi: Terdapat dua studi pasien dan satu studi in vitro. Studi pasien POP menunjukkan hasil yang baik dengan tingkat kekambuhan yang rendah pada pasien yang menerima PRP dibandingkan dengan mereka yang tidak menerima Platelet-Rich Plasma dan studi lain yang melakukan evaluasi satu tahun tidak menemukan adanya kekambuhan setelah pasien menerima Platelet-Rich Plasma di tempat pembedahan. Studi in vitro menunjukkan perlekatan dan proliferasi sel yang baik pada biopsi jaringan vagina dengan Platelet-Rich Plasma yang diaplikasikan pada jaringan tersebut.Kesimpulan: Platelet-Rich Plasma dapat meningkatkan regenerasi jaringan, sehingga berpotensi mengurangi kekambuhan setelah rekonstruksi.Kata kunci: Platelet-Rich Blood Plasma, Prolaps Organ Panggul, Uroginekologi
A Sexual Dysfunction And Quality Of Life Problems Caused By Perineal Pain Cicatrix In A Woman: A Case Report Fakhrizal, Edy; Primananda, M. Lingga
Andalas Obstetrics And Gynecology Journal Vol. 7 No. 1 (2023)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.7.1.338-341.2023

Abstract

Introduction: Sexual dysfunction is a complaint that could happened because of disturbance in complex processwhich coordinated by neurology system, vascular and endocrine system.1 One cause of sexual disfunction isdyspareunia which also followed by quality of life problems. Problems of dyspareunia, sexual dysfunction andquality of life can be measure with VAS, FSFI and WHOQOL instruments. VAS, Visual Analogue Scale, is one ofthe pain rating scales used in epidemiologic and clinical research to measure the intensity or frequency of varioussymptoms.2 FSFI, Female Sexual Function Index, is a multidimensional questionnaire that can show female sexualfunction. This questionnaire consists of 6 domains in which sexual desire, sexual arousal, lubrication, orgasm,sexual satisfaction and pain.3,4,5 WHOQOL-BREF, World Health Organization Quality-of-Life Scale, is a qualityof life assessment developed by the WHOQOL Group with fifteen international field centres, simultaneously, inan attempt to develop a quality of life assessment that would be applicated by cross-culturally.Case Report : Patient came with complaint of pain in genital opening and perineum that felt since 5 months ago.Patient also came with complaint of dyspareunia. Patient had history of vaginal delivery which causing her aperineal rupture. For 5 months, patient could not get intercourse and made her desperated and suffered becauseof her husband desire. Patient also felt inferiority and these problems disturbed her daily activity. VAS was 8,FSFI was 3, and WHOQOL was 71. The perinel ruptured was sutured at the moment of delivery, but after 1 weekpatient started to felt pain at her birth canal. It was the first pregnancy, delivery process was without anyproblems, baby born with 2900 gram of birth weight. From gynecology examination, found a cicatrix at 5 o’clockdirection, any other gynecology organs within normal limit. Diagnose was dyspareunia ec perineal cicatrix withsexual dysfunction and quality of life problems, then urogynecologist decided to do surgery
The Effect of Platelet-Rich Plasma Injection as Therapy for Stress Urinary Incontinence Cases Sumarlin, Sofi; Lubis, Munawar Adhar; Fakhrizal, Edy
Jurnal Ilmu Kedokteran Vol 19, No 1 (2025): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v19i1.2025.14-18

Abstract

Women frequently have stress urinary incontinence (SUI), which has a major negative influence on their quality of life. A non-surgical method of enhancing SUI that shows potential is platelet-rich plasma (PRP) therapy, by improving urethral tissue strength and enhancing the urethral closure mechanism. The usefulness of PRP in increasing urethral resistance and lowering SUI symptoms has been examined in recent literature studies conducted between 2019 and 2023. Although the first results are encouraging, more investigation is required to validate long-term advantages and clinical efficacy in broader groups, as well as to comprehend possible adverse effects and related difficulties. For SUI patients looking for non-surgical options, PRP offers an alluring treatment option with the potential to lessen the need for invasive surgical procedures. However, further development and broader clinical studies are necessary to strengthen these findings and support the clinical use of PRP in the management of SUI to improve quality of life. 
Laser Therapy for Genitourinary Syndrome of Menopause (GSM): A Stratified Meta-Analysis of Histological, Clinical, and Safety Outcomes Vani Ardiani; Sri Wahyu Maryuni; Edy Fakhrizal; Dafnil Akhir Putra
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 10 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i10.1403

Abstract

Background: Genitourinary syndrome of menopause (GSM) is a prevalent and chronic condition that diminishes quality of life. Vaginal laser therapy is a non-hormonal treatment, but its efficacy and safety require rigorous synthesis. This study was conducted to systematically evaluate the efficacy of laser therapy for GSM by prioritizing high-quality evidence and separately analyzing findings from different study designs, while also providing the first meta-analytic overview of safety. Methods: A systematic search of PubMed, Scopus, Embase, and the Cochrane Library was performed for studies published between January 2015 and December 2024. The primary analysis of efficacy was restricted to randomized controlled trials (RCTs). A separate, secondary analysis was performed on prospective cohort studies. Primary outcomes were changes in vaginal epithelial thickness and the Visual Analog Scale (VAS) for dryness. Secondary outcomes included VAS for dyspareunia, vaginal health index (VHI), female sexual function index (FSFI), and systematically extracted adverse events. Data were pooled using a random-effects model. Results: Seven studies (2 RCTs, 5 cohort studies) involving 595 patients were included. In the primary analysis of RCTs, laser therapy resulted in a significant increase in epithelial thickness (Mean Difference [MD] 50.15 µm) and a significant reduction in VAS for dryness (MD -4.54) with low-to-moderate heterogeneity. The secondary analysis of cohort studies also showed significant improvements, but with extremely high and significant heterogeneity (I² > 80%). Across all studies, reported adverse events were consistently mild and transient, including temporary erythema, edema, and minor discharge. No serious adverse events were reported. Conclusion: Based on high-quality evidence from RCTs, vaginal laser therapy produces statistically significant improvements in the histological and clinical parameters of GSM. Evidence from cohort studies supports this finding but demonstrates considerable variability in real-world settings. While short-term safety appears favorable, the inconsistent treatment effect and lack of long-term data necessitate a cautious approach to patient selection and counseling.
Laser Therapy for Genitourinary Syndrome of Menopause (GSM): A Stratified Meta-Analysis of Histological, Clinical, and Safety Outcomes Vani Ardiani; Sri Wahyu Maryuni; Edy Fakhrizal; Dafnil Akhir Putra
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 10 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i10.1403

Abstract

Background: Genitourinary syndrome of menopause (GSM) is a prevalent and chronic condition that diminishes quality of life. Vaginal laser therapy is a non-hormonal treatment, but its efficacy and safety require rigorous synthesis. This study was conducted to systematically evaluate the efficacy of laser therapy for GSM by prioritizing high-quality evidence and separately analyzing findings from different study designs, while also providing the first meta-analytic overview of safety. Methods: A systematic search of PubMed, Scopus, Embase, and the Cochrane Library was performed for studies published between January 2015 and December 2024. The primary analysis of efficacy was restricted to randomized controlled trials (RCTs). A separate, secondary analysis was performed on prospective cohort studies. Primary outcomes were changes in vaginal epithelial thickness and the Visual Analog Scale (VAS) for dryness. Secondary outcomes included VAS for dyspareunia, vaginal health index (VHI), female sexual function index (FSFI), and systematically extracted adverse events. Data were pooled using a random-effects model. Results: Seven studies (2 RCTs, 5 cohort studies) involving 595 patients were included. In the primary analysis of RCTs, laser therapy resulted in a significant increase in epithelial thickness (Mean Difference [MD] 50.15 µm) and a significant reduction in VAS for dryness (MD -4.54) with low-to-moderate heterogeneity. The secondary analysis of cohort studies also showed significant improvements, but with extremely high and significant heterogeneity (I² > 80%). Across all studies, reported adverse events were consistently mild and transient, including temporary erythema, edema, and minor discharge. No serious adverse events were reported. Conclusion: Based on high-quality evidence from RCTs, vaginal laser therapy produces statistically significant improvements in the histological and clinical parameters of GSM. Evidence from cohort studies supports this finding but demonstrates considerable variability in real-world settings. While short-term safety appears favorable, the inconsistent treatment effect and lack of long-term data necessitate a cautious approach to patient selection and counseling.
Co-Authors Budi I. Santoso Dafnil Akhir Putra Dhini Aiyulie Novri Djusad, Suskhan Fernandi Moegni Hutapea, Anastasya Junizaf Junizaf Koerslo, Hamka Lubis, Munawar Adhar M. Lingga Primananda Maryuni, Sri W. Maryuni, Sri Wahyu Oktama, Nizan Dani Primananda, M. Lingga Ruza Prima Rustam Simanjuntak, Arya Marganda Sri Wahyu Maryuni Sri Wahyu Maryuni Sumarlin, Sofi Surahman Hakim Tyas Priyatini Vani Ardiani Yuda, Dika Putra