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All Journal Health Research Journal of Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian
Vania Santika Putri
Politeknik Indonusa Surakarta
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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EFFECT OF COCAMIDOPROPYL BETAINE (CAPB) CONCENTRATION ON PHYSICAL CHARACTERISTIC OF BASIL LEAVES (Ocimum basilicum L.) ESSENTIAL OIL FACIAL Vania Santika Putri; Verawati Hadi; Anita Dwi Nuryani; Ayu Ambarwati
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 2 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i2.1115

Abstract

Atopic dermatitis or often called eczema is a chronic inflammatory skin disorder that often occurs around the face, legs and arms. Decreased skin barrier function can increase the spread of bacteria on the skin surface, especially Staphylococcus aureus. This study aimed to formulate facial wash preparations of basil leaf essential oil using varying concentrations of cocamydopropyl betaine (CAPB) as a surfactant and foam booster. The basil leaf essential oil facial wash was formulated into three formulas with varying concentrations of cocamydopropyl betaine (CAPB), namely F1 (8%), F2 (9%), and F3 (10%). Physical evaluation included organoleptic observations, homogeneity, pH, foam height, and viscosity. Based on the results of organoleptic and homogeneity evaluations, the three facial wash formulas are homogeneous, white in color, and have a distinctive basil smell, with an increasingly watery consistency from F1 to F3, while the pH in the range 4.97 - 5.26, the height foam test of the three formulas was 37–42 mm, and the viscosity was in the range of 2647,1 - 3516,5 cPs. Variations in the CAPB concentration used in the facial wash formulas have a significant effect on the resulting pH and viscosity values, where the higher the CAPB concentration used, the lower pH and viscosity values of the facial wash. However, an increase in CAPB concentration in the facial wash formula (8 %, 9 %, and 10 %) did not have a significant effect on the foam height of the basil leaf essential oil facial wash.
Pengaruh Variasi Konsentrasi PVA Terhadap Evaluasi Sifat Fisik Sediaan Masker Gel Peel-Off Ekstrak Daun Salam Vania Santika Putri; Tiara Natali
Health Research Journal of Indonesia Vol 4 No 5 (2026): Health Research Journal of Indonesia
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/hrji.v4i5.1134

Abstract

Penuaan dini merupakan kondisi percepatan proses degenerasi kulit yang dapat dipicu oleh paparan radikal bebas, sehingga diperlukan intervensi berupa antioksidan topikal. Daun salam (Syzygium polyanthum (Wight) Walp) diketahui memiliki aktivitas antioksidan kuat, sehingga berpotensi dikembangkan dalam sediaan kosmetik anti-aging, salah satunya masker gel peel-off. Penelitian ini bertujuan untuk memformulasikan serta mengevaluasi pengaruh variasi konsentrasi polivinil alkohol (PVA) terhadap karakteristik sediaan masker gel peel-off ekstrak daun salam. Penelitian ini menggunakan metode eksperimental. Ekstraksi daun salam dilakukan dengan metode maserasi menggunakan pelarut etanol 96% dengan perbandingan 1:10. Ekstrak yang diperoleh kemudian diformulasikan menjadi masker gel peel-off dengan variasi konsentrasi PVA, yaitu F1 (10%), F2 (12,5%), dan F3 (15%). Evaluasi sediaan meliputi uji organoleptis, homogenitas, pH, daya sebar, daya lekat, waktu mengering, viskositas, serta uji hedonik. Analisis data dilakukan menggunakan uji One Way ANOVA dan Kruskal-Wallis. Hasil penelitian menunjukkan bahwa seluruh formula memiliki homogenitas yang baik dengan warna dan bau yang seragam, namun berbeda dalam tekstur. Nilai pH berada pada rentang 5,12±0,15 hingga 5,41±0,10, daya sebar 5,05±0,32 hingga 6,14±0,05 cm, daya lekat 5,38±3,03 hingga 41,34±7,95 detik, waktu mengering 16,12±1,99 hingga 24,94±1,08 menit, serta viskositas 20139,9±25,35 hingga 20166,5±9,44 cPs. Uji hedonik menunjukkan bahwa formula F1 (PVA 10%) merupakan formula yang paling disukai panelis. Analisis statistik menunjukkan bahwa variasi konsentrasi PVA berpengaruh signifikan terhadap daya sebar, daya lekat, dan waktu mengering (p<0,05), namun tidak berpengaruh signifikan terhadap pH dan viskositas (p>0,05).
Co-Authors Amalia, Annora Rizky Anita Dwi Nuryani Aptika Oktaviana Trisna Dewi Ardhia Intan Cahyani Ayu Ambarwati Dewi Weni Sari Ratih Dwi Purwanti Risma Anggita Dewi Sugiyanti Sugiyanti Tiara Natali Verawati Hadi Yuliana Salma Eka Ningsih Yunita Dian Permata Sari