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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Bengawan :Jurnal Pengabdian Masyarakat Scientific Journal of Dermatology and Venereology (MJN) Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat IJF (Indonesia Jurnal Farmasi) Medical Sains : Jurnal Ilmiah Kefarmasian
Yunita Dian Permata Sari
Politeknik Indonusa Surakarta
Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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FORMULASI DAN EVALUASI FISIK SEDIAAN LIP CREAM DENGAN PEWARNA ALAMI DARI EKSTRAK DAUN JATI: (Tectona grandis L.f.) Yunita Dian Permata Sari; Iin Suhesti; Kiky Adhianna Sulistyawati
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 6 No. 1 (2022): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v6i1.121

Abstract

Leaf jati (Tectona grandis L.f.) has the pigment anthocyanin which product a red color. Anthocyanin pigments are a group of flavonoid pigments. The purpose of this study was to formulate and physically evaluate lip cream preparations with natural dyes from leaf jati extract (Tectona grandis L.f.). Anthocyanin extraction was carried out by maceration method using 96% ethanol as solvent. Lip cream was made into three formulas with different concentrations of extract leaf jati by 5%,10%,and 15%. The lip cream in each formula was subjected to physical tests including organoleptic test, homogeneity test, pH test, adhesion test, dispersion test, and hedonic test. The results of the organoleptic test of the three formulas have different colors it is pink to red because variation of leaf jati extract used. The results of the homogeneity test showed that the three formulas are homogeneous. The results of the pH test of the three formulas are 4, indicating that all formulas had met the lip pH requirements of 3.8-4.7. The results of the adhesion test are F1=2,42±0,04;F2=3.21±0,03; and F3=4.26±0,02, these results show that only F3 meets the requirements because it is more than 4 seconds. The results of the dispersion test are F1=5.35±0,02;F2=5,21±0,04;and F3=5,10±0,03, the result is qualified because the result is 5-7 cm. The result of the preference test that was most preferred based on color, aroma, moisture, and texture was formula 2. Based on the results of the One Way Anova and Kruskal Wallis tests, there were significant differences in adhesion and dispersion
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN PEGAGAN (Centella asiatica (L.) Urb.) TERHADAP BAKTERI Methicillin Resistant Staphylococcus aureus Muhammad Dani Riano; Annora Rizky Amalia; Yunita Dian Permata Sari
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 7 No. 1 (2023): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v7i1.158

Abstract

MRSA (Methicillin-Resistant Staphylococcus aureus) is one of the gram-positive bacteria that can cause pneumonia. The pegagan plant (Centella asiatica (L.) Urb.) is currently being planted by many people. pegagan leaves have antibacterial activity against bacteria such as Staphylococcus aureus, Staphylococcus mutans, and Escherichia coli. The purpose of this study is to determine whether there is antibacterial activity in pegagan leaves against methicillin-resistant Staphylococcus aureus bacteria. The extraction of pegagan leaf simplisia was carried out by the maceration method. The extract was made with 3 concentrations: 20% b/v, 40% b/v, and 80% b/v. The research method of antibacterial activity testing was carried out by disk diffusion. In this study, the positive control was vancomycin. As for the negative control, a 10% DMSO solution was used. In this study, it was found that the results of pegagan leaf extract had an average inhibition of 20% concentration of 8.75 mm or resistant, 40% concentration of 10.58 mm or resistant, 60% concentration of 11.5 mm or resistant, and a positive control of 18.91 mm or intermediate against MRSA (Methicillin Resistant Staphylococcus aureus) bacteria.
GAMBARAN PENGETAHUAN MASYARAKAT TENTANG DAGUSIBU DI DUKUH POKO RT 02 RW 05 DESA DUWET WONOSARI KLATEN Yuliana Salma Eka Ningsih; Yunita Dian Permata Sari; Vania Santika Putri
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 7 No. 1 (2023): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v7i1.160

Abstract

Drugs are used to cure the disease that is being suffered by the patient. However, theres people who not know the actual use drugs tht are good and right, so that errors in the use of drugs often occur. DAGUSIBU (Get, Use, Save, Discard) is a Drug Awareness Family Movement Program created by the Indonesian Pharmacist Association in achieving public understanding and awareness of the correct use of drugs (Indonesian Pharmacist Association, 2014). The purpose of this study was to determine the level of knowledge about DAGUSIBU as a self-medication effort among the people of Dukuh Poko RT 02 RW 05 Duwet Village, Wonosari, Klaten. This type of research is a non-experimental research with a descriptive survey design of the community in Dukuh Poko RT 02 RW 05 Duwet Village, Wonosari, Klaten. The number of samples used were 86 respondents and the data collection technique used the total sampling method. The data obtained is the percentage of each answer to the questionnaire that has been filled in by the respondent. Based on the results of data processing, it was obtained that the level of public knowledge was in the good category, 57 (66%), 23 (27%) had sufficient knowledge, and 6 (7%) lacked knowledge. So it can be concluded that the average level of knowledge about DAGUSIBU medicine in the Dukuh Poko RT 02 RW 05 community has a good level of knowledge (80%).
FORMULATION OF PEEL-OFF GEL MASK OF COCOA SKIN EXTRACT (Theobroma cacao L) WITH VARIED CONCENTRATION GELLING AGENT Yunita Dian Permata Sari; Diyan Sakti Purwanto; Umi Nafisah
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 1 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i1.1006

Abstract

Cocoa shells are waste from the plantation industry, with a fairly good potential source of energy and protein. The ethanol extract of cocoa shells contains alkaloids, flavonoids, phenols, and tannins. Cocoa shell extract has strong antioxidant activity with an IC50 value of 17.21 ppm and has sunscreen activity. This study aimed to determine the formulation and physical test of a peel-off gel mask with cocoa shell extract (Theobroma cacao L) and to determine its effect. The research method used was an experimental method with variations in the concentration of a combination of HPMC and PVA of 2%:10%, 3%:9%, 4%:8%, 5%:7%, and 0%:12%. The physical tests used on the peel-off gel mask with cocoa shell extract (Theobroma cacao L) included organoleptic, homogeneity, pH, spreadability, drying time, adhesiveness, viscosity, and cycling tests. Based on the results of the research carried out, peel-off gel mask has the characteristics of a brown color, a distinctive extract smell and a thick texture, homogeneous for F1 and F5, and not homogeneous for F2, F3, and F4, sticking force 4.53±0.24 seconds; 5.45±0.36 seconds; 8.94±0.64 seconds; 11.23±0.72 seconds; 3.87±0.70 seconds; spreadability 3.99 ± 0.18 cm; 3.33±0.31 cm; 3.47±0.78 cm; 3.32±0.50 cm; 3.05±0.42 cm; pH 6.17 ± 0.10; 6.16±0.03; 6.15±0.10; 6.11±0.05; 6.42±0.03; viscosity 19481.10±201.10; 20165.50±1.05; 20165.73±2.02; 20182.53±9.47; 14618.40±158.48. The physical stability of the gel mask preparations after treatment showed that the results of the peel-off gel mask preparations, F1 and F5, were stable. Keywords: peel-off gel mask, cocoa shell, extract, gelling agent
Antibacterial Activity of Ethanol Extract of Srikaya Leaves (Annona squamosa Linn) Against the Growth of Acne Vulgaris-Causing Bacteria Staphylococcus epidermidis Amalia, Annora Rizky; Zulaika Febru Zalsabila; Yunita Dian Permata Sari
Scientific Journal of Dermatology and Venereology Vol. 3 No. 1 (2025): Scientific Journal of Dermatology and Venereology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjdv.v2i2.143

Abstract

Introduction: Acne vulgaris, a prevalent skin condition, is primarily triggered by the proliferation of Cutibacterium acnes within pilosebaceous units. However, Staphylococcus epidermidis, a commensal skin bacterium, can exacerbate acne inflammation upon follicular invasion. This study investigates the antibacterial potential of ethanol extract derived from srikaya leaves (Annona squamosa Linn) against S. epidermidis. Methods: Srikaya leaves underwent ethanol extraction via maceration. The extract's antibacterial efficacy was assessed using the agar well diffusion method against S. epidermidis at varying concentrations (25%, 50%, 75%). Zones of inhibition were measured, and minimum inhibitory concentrations (MICs) were determined. Phytochemical screening of the extract was conducted to identify potential bioactive compounds. Results: The ethanol extract of srikaya leaves exhibited significant antibacterial activity against S. epidermidis. Increasing extract concentrations led to larger zones of inhibition, indicating a dose-dependent effect. The MIC of the extract against S. epidermidis was determined to be 50%. Phytochemical analysis revealed the presence of flavonoids, phenols, and alkaloids, which are known for their antimicrobial properties. Conclusion: Ethanol extract of srikaya leaves demonstrates promising antibacterial activity against S. epidermidis, suggesting its potential as a natural therapeutic agent for managing acne vulgaris. Further research is warranted to elucidate the mechanisms of action and evaluate the extract's efficacy in clinical settings.
Edukasi Tentang Diates Melitus Di Lingkungan Rt 07/Rw 03 Jajar, Laweyan Antari, Ester Dwi; Purwanto, Diyan Sakti; Sari, Yunita Dian Permata
Bengawan : Jurnal Pengabdian Masyarakat Vol 5 No 1 (2025): June
Publisher : Politeknik Indonusa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/jurnal_bengawan.v5i1.202

Abstract

Diabetes melitus (DM) atau diabetes merupakan penyakit kelainan metabolisme yang ditandai dengan hiperglikemia (kadar glukosa yang tinggi dalam darah) karena kekurangan insulin, resistensi insulin atau keduanya. Melalui kegiatan edukasi ini, diharapkan masyarakat RT 07/RW 03 Jajar dapat lebih memahami pentingnya menjaga kesehatan, mengenali gejala awal DM, dan menerapkan langkah-langkah pencegahan sejak dini. Pengabdian ini juga merupakan bentuk implementasi tridharma perguruan tinggi dalam mendukung program promotif dan preventif di bidang kesehatan masyarakat. Metode pelaksanaan pengabdian kepada masyarakat ini dilakukan dengan metode ceramah, tanya jawab, dan evaluasi kegiatan. Hasil pengabdian masyarakat ini Perubahan perilaku ini menunjukkan bahwa pengabdian telah berhasil membentuk kesadaran kolektif dan mengarahkan komunitas pada pola pikir preventif. Masyarakat tidak lagi bersikap pasif, melainkan mulai aktif mencari informasi kesehatan dan mendiskusikan kebiasaan hidup sehat dalam lingkungan sosial mereka. Dengan demikian, hasil pengabdian ini mampu mereduksi permasalahan awal, yaitu rendahnya pengetahuan dan kesadaran masyarakat tentang DM. Edukasi yang diberikan telah menjawab kebutuhan informasi, membentuk sikap kritis terhadap gaya hidup, dan memperkuat komitmen masyarakat untuk mencegah DM sejak dini. Hal ini menjadi bukti bahwa tujuan Pengabdian Kepada Masyarakat, yaitu meningkatkan literasi kesehatan dan memberdayakan masyarakat dalam upaya pencegahan penyakit tidak menular, telah tercapai dengan baik.
The Potential of Sugarcane Bagasse (Saccharum officinarum Linn.) as a Basic Ingredient for Making Cosmetics and Its Effectiveness as an Exfoliator and Skin Moisturizer Suhesti, Iin; Sari, Yunita Dian Permata; Oktofiani, Fauziyah; Janah, Aprillia Nurul
Media Farmasi: Jurnal Ilmu Farmasi Vol. 21 No. 1: March 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v21i1.27915

Abstract

Sugarcane bagasse (Saccharum officinarum Linn.) contains most of the phenolic compounds including gallic acid, ferulic acid, epicatechin, quercetin, and kaempferol. Various phenolic compounds contained in sugarcane bagasse, especially phenolic acids, have important bioactivity for the cosmetics industry. The aim of this research is to determine the potential of sugarcane bagasse as an active ingredient in cosmetics and its effectiveness as an exfoliator and skin moisturizer. This research method is experimental, using sugarcane bagasse samples with concentrations of 1%, 3% and 5%. The results of phytochemical screening showed that sugarcane bagasse contains phenolic compounds, flavonoids and phytosterols. Based on the research results, sugarcane bagasse exfoliating gel at concentrations of 1%, 3%, and 5% increased skin tone respectively, namely 1.00 ± 0.67; 0.40±0.49; and 0.30 ± 0.39. Sugarcane bagasse moisturizing gel at concentrations of 1%, 3%, and 5% had a percent increase in skin water content, respectively, namely 6.92 ± 11.094; 2.72±10.21; and 3.36 ± 6.49. Based on SPSS analysis, it is known that variations in the concentration of bagasse extract and the time of use have a significant effect on increasing skin tone. Meanwhile, variations in the concentration of bagasse extract did not have a significant effect on increasing skin water content. However, the time of use has a significant effect on the increase in skin water content. So, it can be concluded that sugarcane bagasse extract has the potential to be an active ingredient in making cosmetics and is effective as an exfoliator and skin moisturizer.
COST OF ILLNESS STROKE TREATMENT: A SYSTEMATIC REVIEW Izzah, Raihana Nurul; Alia, Dina Fatma; Amalia, Annora Rizky; Sari, Yunita Dian Permata
Medical Journal of Nusantara Vol. 5 No. 1 (2026): Medical Journal of Nusantara (MJN)
Publisher : Tahta Media Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55080/mjn.v5i1.1957

Abstract

Cardiovascular disease remains the leading cause of death worldwide, with stroke playing a significant role in increasing morbidity, mortality, and the global economic burden. This study aimed to systematically review the cost of illness and health expenditure associated with stroke across different countries. A systematic review was conducted using PubMed, ScienceDirect, and Springer databases for articles published between 2021 and 2026, following PRISMA guidelines. Studies included in the criteria were original research that reported direct and/or indirect costs due to stroke, both in primary health care facilities and in hospitals. Data extraction, screening, and quality assessment were performed using the CHEERS checklist. A total of 13 studies met the inclusion criteria. The findings showed that most studies (76%) applied the Cost Of Illness (COI) approach, while the rest used Health Expenditure (HE) methods. Direct medical costs, particularly those from inpatient care, constitute the largest component of stroke-related expenditures. Cost estimates show considerable variation between countries, with expenditures tending to be higher in high-income countries than in middle-income countries. Clinical severity, length of hospital stay, stroke subtype, and sociodemographic factors were identified as key determinants influencing total costs. Indirect cost components such as lost productivity and premature death also contribute significantly, but their reporting has not been consistent across studies. In conclusion, stroke imposes a substantial and heterogeneous economic burden influenced by methodological approaches, perspectives, and healthcare system differences. Comprehensive evaluation including both direct and indirect costs is essential to support effective health policy and resource allocation.
PENGEMBANGAN REED DIFFUSER AROMATERAPI MINYAK ATSIRI BUNGA KENANGA (Cananga odorata) TERHADAP AKTIVITAS ANTI STRES PADA MENCIT PUTIH (Mus musculus) Ika Maulia Safitri; Riana Putri Rahmawati; Fahrudin Arif; Yunita Dian Permata Sari
IJF (Indonesia Jurnal Farmasi) Vol 10, No 1 (2025): IJF (Indonesia Jurnal Farmasi)
Publisher : Universitas Muhammadiyah Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26751/ijf.v10i1.3519

Abstract

Stres merupakan reaksi emosional dan psikologis yang muncul ketika tekanan atau beban berlebih. Stres dapat diatasi melalui terapi non farmakologi menggunakan aromaterapi sebagai relaksasi. Bunga kenanga merupakan tanaman yang menghasilkan minyak atsiri yang berguna meredakan stres, ketegangan dan memberikan efek relaksasi. Penelitian ini bertujuan mengevaluasi efektivitas minyak atsiri bunga kenanga dalam menurunkan stres mencit pada konsentrasi 1%, 2% dan 4%. Penelitian ini menggunakan eksperimen laboratorium dengan desain kelompok post test. Variabel bebas pada penelitian ini adalah reed diffuser aromaterapi minyak atsiri bunga kenanga dan variabel terikat penelitian ini yaitu aktivitas antistres pada mencit. Penelitian dilaksanakan di Laboratorium Farmakognosi Universitas Muhammadiyah Kudus bulan Januari – Maret 2026. Induksi stres dilakukan menggunakan metode Forced Swimming Test (FST), kemudian mencit diberikan reed diffuser aromaterapi untuk mengevaluasi efek relaksasi dalam mengatasi stres mencit. Parameter yang diamati meliputi waktu diam mencit dalam mengalami perubahan perilaku kembali aktif seperti semula. Data rata-rata waktu diam setiap kelompok dianalisis uji homogenitas, normalitas, ANOVA dan uji post hoc. Hasil pengujian menunjukkan rata-rata waktu diam pada konsentrasi 1% sebesar 16,1 menit; konsentrasi 2% sebesar 15,7 menit; konsentrasi 4% sebesar 12,2 menit; kontrol negatif sebesar 17,3 menit dan kontrol positif menggunakan reed diffuser bunga kenanga komersial sebesar 11,6 menit. Berdasarkan hasil tersebut, peningkatan konsentrasi minyak atsiri berpengaruh terhadap percepatan efek relaksasi yang ditandai dengan penurunan waktu diam. Konsentrasi 4% merupakan formulasi paling optimal karena menghasilkan waktu diam paling rendah dan mendekati efektivitas kontrol positif. Penelitian selanjutnya diharapkan melakukan uji stabilitas sediaan, uji mutu minyak atsiri dan identifikasi komponen minyak atsiri menggunakan GC-MS.
The LEVEL OF OUTPATIENT SATISFACTION REGARDING PHARMACEUTICAL SERVICES IN KARANGANYAR HEALTH CENTER: TINGKAT KEPUASAN PASIEN RAWAT JALAN TERHADAP PELAYANAN KEFARMASIAN DI PUSKESMAS KARANGANYAR Riyan setiyanto; Yunita Dian Permata Sari; Arjuna Wahyu Utama Putra
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 8 No. 2 (2024): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v8i2.223

Abstract

Puskesmas is a functional organizational and professional service unit that is directly responsible to the head of the district/city regional health service. Health services have an important role inimproving the health and welfare of global society. Health service providers who provide effectiveservices are expected to be able to meet patient expectations and needs well. This study aims to assess the level of satisfaction of outpatients with pharmaceutical services at the Karanganyar Community Health Center by considering aspects such as direct evidence, responsiveness, reliability, empathy and guarantee. This type of research is descriptive research. The research sample was 96 patients. The sampling technique is purposive sampling technique. Data collection uses a questionnaire. The data was analyzed using Microsoft Excel then the data was presented in a table for each satisfaction dimension. Based on the results of research on the level of satisfaction of outpatients with pharmaceutical services at the Karanganyar Community Health Center, it was found that the level of tangible satisfaction was 82.24%, responsiveness 84.24%, reliability 84.83%, empathy 86.52%, assurance 86.03%. The average of all dimensions is 84.77%.
Co-Authors Alia, Dina Fatma Amalia, Annora Rizky Ani Septianingsih Arjuna Wahyu Utama Putra Diyan Sakti Purwanto Fahrudin Arif Ika Maulia Safitri Izzah, Raihana Nurul Kiky Adhianna Sulistyawati Muhammad Dani Riano Purwaningsih Purwaningsih Purwanto, Diyan Sakti Riana Putri Rahmawati Riyan Setiyanto suhesti, iin Umi Nafisah Vania Santika Putri Yuliana Salma Eka Ningsih Zulaika Febru Zalsabila