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DNASe I and structure Catalytic site Nurul Sulviani
JBIO: jurnal biosains (the journal of biosciences) Vol 10, No 1 (2024): JBIO : JURNAL BIOSAINS (THE JOURNAL OF BIOSCIENCES)
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v10i1.43429

Abstract

This Article describes 3Dimention studies carried out of catalytic siteĀ  over the past year which have advanced of understanding the substrate to recognizition and how the catalytic mechanism of the several key DNAse I. The hydrolysis reaction that occurs in DNASe I is influenced by Mg 2+ and Ca 2+ but let the Binding of DNASe I ions is still unclear, the active side is found, the amount and mechanism of Ca2+ and Mg2+ . The results of the review in this article indicate that DNASe I is needed externally from experimental animals and simulations improve the binding reaction of Ca 2+ and Mg 2+ which is supported by some literature that uses crystallographic studies where Ca 2+ ions can stabilize DNASe I and also in the presence of Mg 2+ ions that can accelerate the hydrolytic failure of the cation. The results of the review explain the role of cations collectively electrostatic matching between DNASe I and DNA.
Edukasi dan Konseling Kesehatan Mental di Kalangan Mahasiswa Teuku Muhammad Ilzana; Asyrafun Nisa Adelaidey; Irpan Efendi Rambe; Zanurul Rifhan; Vito Filbert Jayalie; Nurul Sulviani
Marsipature Hutanabe: Jurnal Pengabdian Kepada Masyarakat Vol. 1 No. 02 (2024): Marsipature Hutanabe: Jurnal Pengabdian Kepada Masyarakat
Publisher : CV. Devi Tara Innovations

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Abstract

This community service aims to increase students' awareness, understanding, and skills in maintaining mental health through education and counseling programs. Student life is often filled with academic, social, and adaptable pressures to a new environment that can trigger mental health problems such as stress, anxiety, and depression. The program includes seminars, workshops, and counseling sessions held at several colleges with a focus on introducing the importance of mental health, coping techniques, and appropriate psychological support. This activity involves students' active participation in discussions, role-plays, and simulations, which helps them better understand how to manage emotions and seek help when facing problems. The evaluation of the program showed an increase in students' knowledge and skills in dealing with mental health problems, as well as an increase in the number of students willing to access counseling services. Through this activity, it is hoped that a campus environment that is more supportive of mental health and reduces the stigma of seeking professional help.