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All Journal Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Simatupang, Maria Magdalena
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Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Knowledge and Preventive Behaviour Regarding Diarrheagenic Escherichia Coli Infection Amongst Final-Year Medical Students in Universitas Sumatera Utara Eklesia, Maryori; Simatupang, Maria Magdalena
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 6 No. 3 (2024): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v6i3.15303

Abstract

Background: Escherichia coli, a gram-negative facultative anaerobe bacterium is one of the most important etiologies of acute diarrhea, still a serious public health problem and cause of morbidity and mortality in infants, children, the elderly, and people with immune deficiency. The source of contamination is through the consumption of contaminated food, improperly processed dairy and agricultural products, and contact with people who have poor hygiene. The purpose of the study is to determine the level of knowledge and preventive behavior regarding Diarrheagenic Escherichia coli infection. Method: The type of research in this study is descriptive. The research was conducted by collecting data using a Level of knowledge and preventive behavior regarding the diarrheagenic Escherichia coli infection questionnaire which will be given to respondents. Result: The results were obtained from 100 people. For the level of knowledge, there were 64 (64%) people who had good knowledge, 29 (29%) moderate people, and 7 (7%) low people. For the level of preventive behavior, 81 (81%) people of good behavior were found, 18 (18%) people were moderate and 1 (1%) were low. Conclusion: The majority of final-year medical students of Universitas Sumatera Utara are in a good category both in knowledge and preventive behavior regarding Diarrheagenic Escherichia coli.  
Antimicrobial Activity of the Ethanolic Extract of Durio zibethinus Rind against ESBL-producing Escherichia coli and Klebsiella pneumoniae : Antimicrobial Activity of the Ethanolic Extract of Durian Rind against ESBL-producing E. coli and K. pneumoniae Kannady, Johnson; Mayasari, Evita; Mardiani, Tengku Helvi; Hutagalung, Sunna Vyatra; Alona, Ivana; Simatupang, Maria Magdalena
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 1 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i1.19027

Abstract

Background: Durio zibethinus (durian) contains secondary metabolites with antibacterial potency, such as alkaloids, flavonoids, saponins, tannins, and glycosides. Indonesia is one of the world’s largest producing countries of durian, yet the thorny part of the fruit rind often ends up as waste. Investigations of durian rind for its antimicrobial activity will maximize the benefits and prevent waste accumulation. Objective: In this experimental study, we analyzed the antimicrobial activity of ethanolic extract of durian rind against extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and K. pneumoniae in vitro. Methods: This study used a one-group posttest-only design. The disc diffusion method for antimicrobial susceptibility test was used to test the ethanolic extract of durian rind against ESBL-producing E. coli and K. pneumoniae, each with six experimental repetitions to observe the inhibition zone produced around discs containing the extracts at various concentrations (12.5%, 25%, 50%, 75%, 80%, and 100%). Results: Ethanolic extract of durian rind showed an inhibition zone against ESBL-producing E. coli at the extract concentration of 50%, with an average inhibition zone of 3.57 mm. The inhibition zone was also observed against ESBL-producing K. pneumoniae at the extract concentration of 75%, with an average inhibition zone of 3.73 mm. Conclusions: The ethanolic extract of durian rind showed inhibition zones against ESBL-producing E. coli and K. pneumoniae, showing its potential antimicrobial activity in vitro.
Co-Authors Alona, Ivana Eklesia, Maryori Evita Mayasari Hutagalung, Sunna Vyatra Kannady, Johnson Mardiani, Tengku Helvi