Article Per Year (5 Year)
p-Index From 2020 - 2025
0.888
P-Index
This Author published in this journals
All Journal Majalah Kedokteran Andalas Sumatera Medical Journal Journal of Community Service and Empowerment Narra J Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Evita Mayasari
Department Of Microbiology, Faculty Of Medicine, Universitas Sumatera Utara
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Other

Published : 5 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 5 Documents
Search

 1 
PREVALENCE OF ACINETOBACTER BAUMANNII ISOLATED FROM CLINICAL SPECIMENS IN ADAM MALIK HOSPITAL Evita Mayasari; Cherry Siregar
Majalah Kedokteran Andalas Vol 37, No 1 (2014): Published in May 2014
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (326.994 KB) | DOI: 10.22338/mka.v37.i1.p1-7.2014

Abstract

AbstrakAcinetobacter baumannii merupakan spesies Acinetobacter spp. tersering diisolasi darimanusia, dan lebih sering dijumpai pada infeksi nosokomial dibandingkan dengan infeksi dikomunitas. Eksistensi bakteri ini di lingkungan terkait dengan keragaman reservoir, kemampuanmemperoleh gen pembawa sifat resisten antimikroba, dan sifat resisten terhadap pengeringan.Infeksi disebabkan strain A.baumannii yang resisten terhadap banyak antibiotik tidak mudahdikendalikan dan menjadi permasalahan di berbagai negara. Penelitian ini bertujuan untukmengetahui prevalensi A.baumannii dari spesimen klinis di instalasi mikrobiologi klinik RSUPHaji Adam Malik serta pola kepekaannya terhadap berbagai antibiotik. Identifikasi dan ujikepekaan menggunakan mesin otomatis Vitek 2 dengan Advanced Expert System (AES).Penelitian ini menemukan 644/3693 (17,44%) isolat A.baumannii dari berbagai spesimen klinis.A.baumannii paling banyak diisolasi dari spesimen dahak. Penelitian ini menemukan 147/644(23%) bahwa isolat carbapenem-resistent A.baumannii (imipenem dan meropenem). Sebagianbesar isolat sensitif terhadap colistin, amikacin dan tigecycline. Prevalensi A.baumanni yangditemukan pada penelitian ini adalah rendah namun resistensinya tinggi terhadap antibiotikterutama golongan penicillin, cephalosporin dan fluoroquinolon.AbstractAcinetobacter baumannii is the most frequent species of Acinetobacter spp. isolated fromhumans and more common in nosocomial infection than it is in community acquired infection.A.baumannii existence in environment is associated with the diversity of its reservoirs, itscapacity to accumulate genes of antimicrobial resistence, and its resistence to desiccation.Infection of Multidrug resistent (MDR) strain of A.baumannii is not easy to manage and it hasbecome a problem in many countries. The aim of this retrospective study was to investigatethe prevalence of A.baumannii from routine clinical specimens sent to clinical microbiologylaboratory RSUP HAM Medan and its susceptibility pattern to various antibiotics. Identificationand susceptibility testing of A. baumannii was performed by Vitek 2 with Advanced ExpertSystem (AES). A total of 644/3693 (17.44%) A.baumannii isolates were identified from variousclinical specimens. From those isolates, there were 147 (23%) isolates of carbapenemresistentA.baumannii (imipenem and meropenem). A.baumannii mainly isolated from sputumspecimens, and most isolates were highly sensitive to colistin, amikacin and tigecycline.Low prevalence of A.baumannii was found in this study. However, the isolates showed highresistence level to antibiotics, particularly penicillin, cephalosporin and fluoroquinolones.
Improving knowledge and attitude to tackle COVID-19 transmission in a health care facility of North Sumatra’s village Evita Mayasari; Lokot D. Lubis; Nuraiza Meutia; Cut A. Adella; Eka R. Megawati
Journal of Community Service and Empowerment Vol. 4 No. 2 (2023): August
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/jcse.v4i2.25205

Abstract

COVID-19 hits Indonesia with massive social restrictions in many aspects of life. In some Indonesian rural areas, information related to the pandemic through online platforms and social media is accessible. However, most of the information is inaccurate. Improving individual knowledge is crucial to support the government’s campaign for COVID-19 prevention. This cross-sectional, pretest-posttest study aims to evaluate the knowledge and attitude of health personnel toward COVID-19 prevention in a primary healthcare facility in a rural area of North Sumatra. All twenty-two health personnel who worked in the hospital during the study were asked to fill in a two-sectioned questionnaire. The first section contained questions related to knowledge, and the second section was related to attitude toward COVID-19. Following the educational activity, each health personnel filled in the same questionnaire again. We analyzed the data statistically using two-way ANOVA (p<0.05, 95% CI). There were increases in knowledge (p < 0.001) and attitude (p = 0.0002) of the health personnel after the educational activity. Educational activity improves health personnel’s knowledge and attitude regarding COVID-19 prevention.  
The Relationship between Knowledge and Attitude with Behavior of Preventing Leptospirosis in Healthcare Workers at the Binjai City Yolanda Hanalena; Evita Mayasari
Sumatera Medical Journal Vol. 5 No. 1 (2022): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v5i1.7845

Abstract

Leptospirosis is an infectious disease caused by spirochete from the genus Leptospira, namely Leptospira interrogans which is pathogenic for both humans and animals. L. interrogans infection is often associated with flooding, where L. interrogans is carried from soil contaminated with animal urine reservoirs and settles in water. Leptospirosis is estimated to cause 1030000 cases and 58900 deaths annually worldwide. Until now, Leptospirosis is still a threat to public health because it causes Extraordinary Events (KLB) in several regions in Indonesia. Leptospirosis outbreaks are related to the presence of risk factors, namely the high population of rats as reservoirs of Leptospira spp., poor environmental sanitation, and the increasing number of flood areas in Indonesia. The purpose of this study was to determine the relationship between knowledge and attitude with the behavior of preventing Leptospirosis in healthcare workers at the Sub-District Health Center, Binjai Timur, Binjai City, against Leptospirosis. This research is an analytic study with a cross sectional design. The research was conducted using a questionnaire instrument of knowledge level about Leptospirosis, attitudes towards Leptospirosis, and preventive behavior towards Leptospirosis.
Mesenchymal stem cells for immune modulation in systemic lupus erythematosus: From bench research to clinical applications Ginting, Andi R.; Munir, Delfitri; Amin, Mustafa M.; Darlan, Dewi M.; Putra, Agung; Rusda, Muhammad; Mutiara, Erna; Mayasari, Evita; Rozi, Muhammad F.
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.994

Abstract

Systemic lupus erythematosus (SLE) is a prevalent autoimmune disease affecting multiple organ systems. Disease progression is inevitable as part of its natural course, necessitating aggressive therapeutic strategies, particularly with the use of immunosuppressants. Long-term use of steroids and other immunosuppressants is associated with significant adverse effects. Mesenchymal stem cells (MSCs) have been shown to modulate the immune response, leading to immunosuppressive effects against self-antigens. MSCs have demonstrated the ability to modulate several immune cell populations, contributing to favorable outcomes in controlling immune and inflammatory conditions. Recent evidence has shown an increase in Treg and Breg cell subsets following MSC administration, along with modulation of other immune cells, including dendritic cells, B cells, and T cells. However, the balance between MSC pro-inflammatory and anti-inflammatory phenotypic activation remains a critical factor in determining therapeutic outcomes. Various covariates also influence the efficacy of MSC therapy. The aim of this study was to provide a comprehensive overview of the utilization of mesenchymal stem cells (MSCs) in SLE treatment, leveraging their immunomodulatory and immunosuppressive capabilities. Understanding the fundamental preclinical effects of MSCs and recent findings from clinical studies may enhance the potential of MSC therapy in the management of SLE patients.
Antimicrobial Activity of the Ethanolic Extract of Durio zibethinus Rind against ESBL-producing Escherichia coli and Klebsiella pneumoniae : Antimicrobial Activity of the Ethanolic Extract of Durian Rind against ESBL-producing E. coli and K. pneumoniae Kannady, Johnson; Mayasari, Evita; Mardiani, Tengku Helvi; Hutagalung, Sunna Vyatra; Alona, Ivana; Simatupang, Maria Magdalena
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 1 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i1.19027

Abstract

Background: Durio zibethinus (durian) contains secondary metabolites with antibacterial potency, such as alkaloids, flavonoids, saponins, tannins, and glycosides. Indonesia is one of the world’s largest producing countries of durian, yet the thorny part of the fruit rind often ends up as waste. Investigations of durian rind for its antimicrobial activity will maximize the benefits and prevent waste accumulation. Objective: In this experimental study, we analyzed the antimicrobial activity of ethanolic extract of durian rind against extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and K. pneumoniae in vitro. Methods: This study used a one-group posttest-only design. The disc diffusion method for antimicrobial susceptibility test was used to test the ethanolic extract of durian rind against ESBL-producing E. coli and K. pneumoniae, each with six experimental repetitions to observe the inhibition zone produced around discs containing the extracts at various concentrations (12.5%, 25%, 50%, 75%, 80%, and 100%). Results: Ethanolic extract of durian rind showed an inhibition zone against ESBL-producing E. coli at the extract concentration of 50%, with an average inhibition zone of 3.57 mm. The inhibition zone was also observed against ESBL-producing K. pneumoniae at the extract concentration of 75%, with an average inhibition zone of 3.73 mm. Conclusions: The ethanolic extract of durian rind showed inhibition zones against ESBL-producing E. coli and K. pneumoniae, showing its potential antimicrobial activity in vitro.
Co-Authors Agung Putra Alona, Ivana Amin, Mustafa M. Cherry Siregar Cut A. Adella Darlan, Dewi M. Delfitri Munir Eka R. Megawati Erna Mutiara Ginting, Andi R. Hutagalung, Sunna Vyatra Kannady, Johnson Lokot D. Lubis Mardiani, Tengku Helvi Nuraiza Meutia Rozi, Muhammad F. Rusda, Muhammad Simatupang, Maria Magdalena Yolanda Hanalena