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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Ners Jurnal Mandala Pengabdian Masyarakat JUKESHUM: Jurnal Pengabdian Masyarakat Medical Sains : Jurnal Ilmiah Kefarmasian
Jeli Marlita
Universitas Hamzanwadi
Humanities Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences

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ANALYSIS OF NaOCl CONTENT OF HAND & BODY LOTION AND FACE WASH CREAM BY IODOMETRIC TITRATION METHOD Jeli Marlita; Yuyun Febriani; Risma Hayatun Nufus; Muhlisun Azim; Baiq Maylinda Gemantari
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 2 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i2.1242

Abstract

Cosmetics are needed by the public, such as hand and body lotions and face brightening creams, and there are many misuses of hazardous chemicals in cosmetics, including lotions and face brightening creams. Sodium hypochlorite, a  hazardous chemical, can cause skin damage, such as irritation, rash, hypersensitivity, and burns. The purpose of this study was to determine the presence of sodium hypochlorite compounds and sodium hypochlorite in hand and body lotion cosmetics and face brightening cream. The method used in this research was qualitative analysis with color reaction and quantitative analysis with iodometric titration. The results qualitatively showed that color changes occurred in all samples. NaOCl concentration in hand and body lotion at 0.2% concentration showed an average NaOCl concentration of 3.263 % ± 0.25 and face brightening cream concentration at an average concentration of 10 mg showed NaOCl levels of 88.933 % ± 7.57. Based on this, it was concluded that in the samples of hand and body lotion and face brightening cream, sodium hypochlorite compounds with different levels. Therefore, these samples could have side effects and toxicity in their usefulness as cosmetics. Keywords: Hand & body lotion, face brightening cream, sodium hypochlorite (NaOCl), iodometric titration
The Influence of Socialization on Students' Knowledge Levels About Antibiotic Resistance in Selong District, East Lombok: Pengaruh Edukasi Terhadap Tingkat Pengetahuan Siswa Tentang Resistensi Antibiotik di Kecamatan Selong, Lombok Timur Risma Fatmayanti, Baiq; Ramadhan, Leny; Rafsanjani, Arief; Marlita, Jeli; Azim, Muhlisun; Febriani, Yuyun
Jukeshum: Jurnal Pengabdian Masyarakat Vol. 5 No. 2 (2025): Edisi Juli 2025
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/jukeshum.v5i2.1277

Abstract

Antibiotics are drugs used to treat bacterial infections. Irrational use of antibiotics without a doctor's prescription causes antibiotic resistance. West Nusa Tenggara province is ranked sixth with the largest number of antibiotic consumption without a doctor's prescription so the incidence of antibiotic resistance increases. This community service aims to provide antibiotic resistance education to high school students in Selong District. The community service method was carried out at SMAN 1 Selong and SMAN 2 Selong which started with pretest, socialization, and posttest activities to measure students' knowledge of antibiotic resistance before and after socialization. The significance test of changes in students' knowledge levels before and after socialization was conducted using a paired sample t-test. The socialization participants from SMAN 1 Selong and SMAN 2 Selong consisted of 141 high school students in grade XI with an average age of 16. The pretest and posttest data analysis showed that students' knowledge levels regarding antibiotic resistance increased from 41% to 59% at SMAN 1 Selong and 42% to 58% at SMAN 2 Selong after socialization. The average value of students' knowledge about antibiotic resistance increased from 10.04 points to 14.73 points for SMAN 1 Selong and 10.33 points to 14.16 points for SMAN 2 Selong after the socialization was given from a total of 17 maximum points that could be obtained. The results of data analysis using paired sample t-test showed a significant difference (p<0.05) in the average level of student knowledge before and after the socialization activity was carried out. Thus, the antibiotic resistance socialization activity has successfully increased student knowledge in Selong District, especially at SMAN 1 Selong and SMAN 2 Selong effectively.
Antioxidant Activity Of Ethanol Extract And Ethyl Acetate Fraction Of Soursop (Annona Muricata) Leaves In Vitro Marlita, Jeli; Sujono, Tanti Azizah
Jurnal Ners Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v8i1.21929

Abstract

Antioxidants play an active role and are responsible for counteracting free radicals in the body through the process of inhibiting oxidation reactions. Secondary metabolite compounds of phenolic and flavonoid groups are compounds that are widely found in Annona muricata plants that have potential as antioxidants. The purpose of this study was to determine the antioxidant activity of soursop (Annona muricata) leaves using two methods, namely Ferric Reduction Antioxidant Power (FRAP) and 2,2-diphenyl-1-picrylhydrazyl (DPPH). The extraction method used is maceration method with 70% ethanol solvent, then fractionation using liquid-liquid extraction method, antioxidant test using DPPH and FRAP methods with measurement of levels using UV-Vis spectrophotometry. From the results of maceration, the yield of ethanol extract was 21% from 500 g dry simplisia of soursop leaves and the yield of ethyl acetate fraction was 32.78% from 50 g thick ethanol extract. The results of antioxidant activity test by FRAP method on ethanol extract and ethyl acetate fraction samples were 7.790 and 10.026 mgAAE/g, respectively. Both samples showed very strong antioxidant activity. In DPPH method, ethanol extract showed strong antioxidant activity with IC50 value of 63.947 µg/mL and ethyl acetate fraction showed very strong antioxidant activity with IC50 value of 6.702 µg/mL. From the results, it can be concluded that the ethyl acetate fraction showed very strong antioxidant activity in the DPPH and FRAP test methods, while the ethanol extract showed very strong antioxidant activity in the FRAP test method and strong antioxidant activity in the DPPH test method.
Inovasi Produksi Mie Analog di Desa Masbagik Timur: Solusi Pangan Fungsional Untuk Diabetes dan Stunting Febriani, Yuyun; Marlita, Jeli; Gunawan, Indra
Jurnal Mandala Pengabdian Masyarakat Vol. 6 No. 2 (2025): Jurnal Mandala Pengabdian Masyarakat
Publisher : Progran Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpm.v6i2.777

Abstract

Stunting dan diabetes melitus merupakan suatu kondisi kronis yang pada dasarnya memiliki akar penyebab yang sama, yaitu ketidakseimbangan gizi dalam jangka panjang. Kekurangan gizi pada masa awal kehidupan mengakibatkan perubahan metabolisme yang dapat meningkatkan resiko terjadinya diabetes melitus pada usia dewasa. Oleh karena itu, nilai angka kecukupan gizi produk pangan sangat penting untuk memastikan kemanannya pada kedua kondisi tersebut. Permasalahan gizi dan kasus diabetes mellitus menjadi tantangan besar bidang kesehatan. Tingginya angka prevalensi per tahunnya menjadi kedua kasus yang serius. Tujuan pengabdian ini adalah melakukan pendampingan pengembangan produk olahan pangan berupa mie analog dan tepung mocaf untuk pengendalian stunting dan diabetes melitus. Metode yang digunakan yaitu produksi, diversifikasi produk, dan pengecekan kadar kecukupan gizi produk pangan. Hasil yang diperoleh berupa mie analog rasa original, rasa kacang lebui, rasa rumput laut, dan rasa daun kelor. Diversifikasi (pengembangan) produk berupa tepung mocaf. Nilai kadar zat gizi karbohidrat berkisar antara 72-89%, protein 0.7-5.8%, dan lemak 0.4-11%. Nilai ini menunjukkan dengan tingginya karbohidrat dan protein, serta rendahnya kadar lemak membuat potensi tepung mocaf dan mie analog berperan dalam hal memenuhi kecukupan gizi sehingga mengurangi resiko terjadinya diabetes melitus dan stunting. Kesimpulan, mie analog dan tepung mocaf memiliki nilai kadar zat gizi yang cukup baik dan dapat menjadi solusi alternaif pangan bergizi dan fungsional untuk pengendalian stunting dan diabetes melitus.
Efficacy of Sodium Hypochlorite (NaOCl) Against Gram Positive and Gram Negative Bacteria: A Systematic Literature Review Marlita, Jeli; Febriani, Yuyun; Fatmayanti, Baiq Risma; Ramadhan, Leny
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol. 22 No. 2 (2025): Jurnal Ilmu Farmasi dan Farmasi Klinis
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v22i2.12508

Abstract

Sodium hypochlorite (NaOCl) is a chemical compound that acts as a strong oxidizer commonly used as an antibacterial, antiseptic, and disinfectant in various pharmaceutical and health applications. This systematic review aims to evaluate the antibacterial activity of NaOCl against various types of bacteria based on the PICO framework. Literature searches were conducted through the PubMed, ScienceDirect, and Scopus databases for publications from 2017 to 2024. Inclusion criteria included all types of bacteria, the use of NaOCl as an antibacterial or antimicrobial agent, and articles published within that time frame. The interventions reviewed were the use of NaOCl at various concentrations, while the control group referred to conditions without treatment or a comparative antibacterial agent. The results were determined based on antimicrobial activity against the bacteria tested. Two stages of independent literature searches were conducted according to the established inclusion and exclusion criteria. This review shows that NaOCl has significant antibacterial activity against various bacteria, with effectiveness depending on the concentration and characteristics of the target microorganisms.
Co-Authors Arief Rafsanjani Baiq Maylinda Gemantari Baiq Risma Fatmayanti Indra Gunawan Leny Ramadhan Muhlisun Azim Risma Hayatun Nufus Tanti Azizah Sujono Yuyun Febriani