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Analisis Survival Suhu Tubuh pada Pasien Pneumonia yang Diberikan Vitamin D Arief Rafsanjani; Endang Darmawan; Nurcholid Umam Kurniawan
Jurnal Surya Medika (JSM) Vol 5 No 2 (2020): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (183.692 KB) | DOI: 10.33084/jsm.v5i2.1319

Abstract

Pneumonia is caused due to an infection in the lungs so antibiotics need to be administered for its management. Giving antibiotic combination therapy gives pretty good results in some cases, but the problem of mortality rates that occur is still high, it is necessary to be given additional therapy to increase the patient's cure rate. One of the adjuvant therapies that can be given is vitamin D. vitamin D is known to play a role in the body’s defense function, both in natural and adaptive immunity and plays a role in the body’s defense in cases of infections, allergies, malignancies, and autoimmune. This research was an experimental Double-Blind Randomized Clinical Trial. The study subjects were pediatric patients aged six months to 18 years who were divided into two groups, namely the intervention group (n = 35) and the control group (n = 35). The intervention group received vitamin D, while the control group received a placebo. Data observed were body temperature. This study aimed to determine the effectiveness of vitamin D based on the parameters of fever in pediatric patients with pneumonia infections treated at the Muhammadiyah Bantul Hospital. The results of this study prove that vitamin D is able to provide a chance of survival on the third day after the administration of vitamin D
Analisis Kaplan Meier terhadap Perbaikan Klinis Batuk pada Pasien Pneumonia Anak yang Diberikan Terapi Tambahan Vitamin D Arief Rafsanjani; Endang Darmawan; Nurcholid Umam Kurniawan; Tri Puspita Yuliana; Aditya Noviadi Rakhmatullah
Jurnal Surya Medika (JSM) Vol 7 No 1 (2021): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i1.2632

Abstract

Pneumonia is the leading cause of death in children under five years of age and contributed to 14% of total global child deaths in 2013. Pneumonia is an inflammation of the lungs caused by bacteria, viruses, fungi, parasites and attacks the lung parenchyma. After receiving antibiotic therapy, the cure rate for pneumonia is relatively high, but the mortality rate due to pneumonia infection is still high. Therefore there needs to be an effort to add therapy to improve patient clinical outcomes. Vitamin D plays a role in the body's defense function, both in natural and adaptive immunity and in the body's defense in cases of infection, malignancy, and autoimmunity. This study was an experimental double-blind, randomized clinical trial that was analyzed using Kaplan Meier. The research subjects were children aged six months to 18 years divided into two treatment groups, namely the treatment group (n = 35) and the control group (n = 35). The treatment group received vitamin D, while the control group a placebo. The data taken included the results of clinical studies of patients. This study indicates that vitamin D is effective in accelerating the cough frequency of patients infected with pneumonia.
Combination of Traditional Medicine and Synthesis Medicine Therapy for Hypertension and Diabetic Patients Ersi Arviana Ihsan; Fitriwati Sovia; Erma Ewisa Oktresia; Tri Puspita Yuliana; Sulistia Ardyati; Arief Rafsanjani
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 18 No. 01 Juli 2021
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v18i1.9348

Abstract

Hypertension and diabetic are interrelated diseases affect atherosclerosis. This study aims to analyze the combination of traditional medicines and synthetic medicine with a job background for patients with hypertension and diabetic. Case-control study method retrieves patient data with medical records. Sampling was done with a purposive sampling technique of 30 respondents conducted in March-June at Labuhan Lombok Health Center. The results showed the percentage of diabetic patients was 26.67% for men and 73.33% for women with a background of 60% of traders, 20% of farmers, 13.3% of fishermen, and housewives of 6.7%. Furthermore, for hypertension patients, the percentage was 13.33% for men and 86.67% for women with a background of 40% of traders, 53.3% for farmers, 6.7% for fishermen. For traditional medicine used are Moringa oleifera L., Cucumis sativus L., jamu gendong, Averrhoa bilimbi L., Curcuma longa L., and Artocarpus camansi Blanco. Based on this, the risk factors for women are more generous than for men, and the use of a combination of drugs gives positive results in improving health.
Pengetahuan masyarakat dan pemanfaatan tanaman obat keluarga di desa toya aikmel utara Muhlisun Azim; Arief Rafsanjani; Tripuspita Yuliana; Puspawan Hariadi
Lentera Negeri Vol 2, No 1 (2021): Lentera Negeri
Publisher : Indonesian Institute For Counseling, Education and Therapy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (787.908 KB) | DOI: 10.29210/99330

Abstract

Family Medicinal Plants (TOGA) is an alternative in achieving GERMAS (Healthy Living Community Movement) as an effort to achieve traditional independent health. The success of the use of TOGA is strongly influenced by the level of public knowledge about the benefits of the type of medicinal plants which has been empirically investigated. The data obtained is qualitative data with descriptive approach analysis method. Data collection was carried out by conducting observations, interviews and technical training to the community in an effort to provide knowledge about TOGA and the creation of a TOGA demonstration plot. The results obtained from this activity are the emergence of public awareness of the use of home yard land for the manufacture of living pharmacies as an effort to achieve independent health and the emergence of public interest in the use of TOGA as a UMKM product in the form of packaged drink sachets as a pilot. The importance of public knowledge about TOGA is needed in supporting the success of achieving independent health and efforts to utilize local biological resources in initiating the manufacture of herbal plant-based UMKM products.
PENGARUH PEMBERIAN EKSTRAK LABU AIR (Lagenaria siceraria) TERHADAP PENURUNAN KADAR GULA DARAH PUASA PADA MENCIT YANG DIINDUKSI ALOKSAN Hamdi, Muhammad Irsyadul; rafsanjani, arief; yuliana, tri puspita
Jurnal Ilmiah Pharmacy Vol 10, No 1 (2023)
Publisher : Sekolah Tinggi Kesehatan Al-Fatah Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52161/jiphar.v10i1.435

Abstract

Diabetes Melitus merupakan salah satu masalah kesehatan dunia. Organisasi Kesehatan dunia (WHO) menaksirkan adanya kenaikan jumlah penderita DM yang signifikan terlepas dari predikatnya menjadi salah satu permasalahan kesehatan global. Pada tahun 2045 ditaksirkan jumlah penderita DM bisa mencapai angka 700 juta penderita (WHO, 2016). Manfaat kesehatan yang dihasilkan asal buah labu air salah  satunya berpotensi sebagai antidiabetik, labu air mengandung dua senyawa metabolit sekunder yang sangat berperan sebagai antidaibetik yakni Flavonoid dan Saponin. Dari manfaat dan kandungan yang dimiliki labu air tersebut maka peneliti tertarik untuk melakukan uji efektivitas ekstrak labu air terhadap penurunan kadar gula darah puasa pada mencit. Jenis penelitian yang diterapkan adalah penelitian kuantitatif dengan desain eksperimental melalui rancangan Pre- test and Post-test with control group. Penelitian ini terdiri dari kelompok kontrol negatif, kontrol positif, perlakuan dosis 1 (8,4 mg/20 gr BB) perlakuan 2 (11,2 mg/20 gr BB) dan perlakuan dosis 3 (14 mg/20 gr BB). Berdasarkan hasil uji analisis one-way ANOVA menunjukkan terdapat perbedaan bermakna dari kelompok kontrol negatif dan kelompok kontrol positif, perlakuan dosis 1, dosis 2, dan dosis 3 dengan nilai signifikansi p<0,05. Kesimpulan dari penelitian ini ialah ekstrak labu air memiliki pengaruh dalam menurunkan kadar gula darah puasa pada mencit yang diinduksi aloksan.
Identifikasi Interaksi Obat Pada Pasien Lansia Yang Berisiko Sindrom Metabolik Di Puskesmas Aikmel Sovia, Fitriwati; Hardiyanti, Novi; Rafsanjani, Arief; Oktresia, Erma Ewisa
Jurnal Farmasi & Sains Indonesia Vol 6 No 1 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no1p39-46

Abstract

Metabolic syndrome is an increasingly prevalent health problem in both developed and developing countries, including Indonesia. The treatment of metabolic syndrome often involves polypharmacy, which increases the potential for drug interactions. Drug interactions are considered clinically important if they can cause increased toxicity or reduce the therapeutic effects of drugs, leading to a failure to achieve the desired therapeutic effect. Reported cases of drug interactions are more common in elderly patients. This study aims to determine the potential Drug-drug Interactions (DDIs) in elderly patients at risk of metabolic syndrome at Puskesmas Aikmel. The study uses a descriptive observational method with prospective data collection. The population in this study consists of outpatient patients at Puskesmas Aikmel from May to July 2021, meeting the inclusion criteria: patients diagnosed at risk of metabolic syndrome, elderly patients (age ? 60 years), and using a minimum of 2 drugs. Sampling was done using total sampling technique. The results of the study indicate 99 cases of potential drug interactions identified in the prescription of elderly patients. The drug classes with potential interactions include antihypertensive drugs in 51 (51.51%) cases, antihyperglycemic drugs in 42 (42.42%) cases, and dyslipidemia drugs in 6 (6.06%) cases. The types of drug interactions observed were pharmacokinetic interactions in 37 (37.37%) cases, pharmacodynamic interactions in 58 (58.58%) cases, and unknown interactions in 4 (4.04%) cases. The severity of these potential interactions was classified as minor in 5 (5.05%) cases, moderate in 86 (86.87%) cases, and major in 8 (8.08%) cases.
Efektivitas Sediaan Krim Daun Pki (Choromolaena Odorata L.) Sebagai Penyembuh Luka Sayat pada Kelinci (Orctolagus Cuniculus): Effectiveness of Pki (Chromolaena Odorata L.) Leaf Cream Preparation for Healing Cut Wounds in Rabbits (Oryctolagus Cuniculus) Rafsanjani, Arief; Wati, Ambar; Yuliana, Tri Puspita
Jurnal Surya Medika (JSM) Vol. 11 No. 1 (2025): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v11i2.6095

Abstract

Uji Efektivitas Sediaan Krim Daun Pki (Chromolaena Odorata L.) Sebagai Penyembuh Luka Sayat Pada Kelinci (Oryctolagus Cuniculus). Daun pki, secara tradisional digunakan untuk penyembuhan luka, dan infeksi. Tujuan dari penelitian untuk mengetahui efektivitas lama penyembuhan, konsentrasi serta perbandingan efektivitas ekstrak krim daun pki dengan obat komersial. Penelitian ini bersifat eksperimental laboratories dengan metode post test only control group design. Pembuatan formulasi krim dengan konsentrasi ekstrak daun pki FI (10%), FII (15%), dan FIII (20%) sebanyak 50 gr serta KTP, KE, K-, K+. Dilakukan uji efektivitas penyembuhan luka sayat pada hewan uji dengan membandingkan semua kelompok. Parameter pada penelitian ini yaitu eritema, edema dan penutupan luka dengan mengukur panjang luka sayat menggunakan penggaris. Perlakuan pada FI krim ekstrak daun pki dosis 10% menunjukan waktu penyembuhan luka sayat pada kelinci paling cepat rata-rata pada hari ke- 8. Berdasarkan hasil statistika uji Anova (p<0,005) pada penelitian ini, bahwa krim ekstrak daun pki, formulasi dalam bentuk sediaan krim efektif sebagai penyembuh luka sayat. Selajutnya dilakukan uji Tukey dimana dapat disimpulakn terdapat perbedaan signifikan antara FI dengan KTP, KE, K-, FII, FIII, sedangkan FI tidak terdapat perbedaan yang signifikan dengan salep poviden iodin.
Efektivitas Ekstrak Etanol Daun Ciplukan (Physalis angulata L.) Terhadap Penurunan Kadar Trigliserida Pada Mencit (Mus musculus) Rafsanjani, Arief; Salsabila, Aulia; Yuliana, Tri Puspita
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 6, No 2 (2025): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v6i2.27605

Abstract

Hypertriglyceridemia is a condition when triglyceride levels in the blood increase. High triglyceride levels can cause atherosclerosis, which is a risk factor for cardiovascular disease. The ciplukan plant contains chemical compounds, namely flavonoid compounds. Flavonoid compounds can reduce triglyceride levels by increasing the activity of the lipoprotein lipase enzyme. This research aims to determine the potential of Ciplukan (Physalis angulata L) leaf extract in reducing triglyceride levels in mice (Mus musculus). This type of research is experimental research with a Pretest-Posttest Control Group design. This study consisted of a negative control group, positive control, treatment dose I (2.8 mg/20 gr BW), dose II (5.6 mg/20 gr BW), and dose III (8.4 mg/20 gr BW ). Based on the results of the pne-way ANOVA analysis test, it showed significant differences between the negative control group and the positive control group, treatment dose I, dose II, and dose III with a significance value of p<0.05. The conclusion of this research is that the ethanol extract of ciplukan leaves has the potential to reduce triglyceride levels in mice induced by quail egg yolk.
The Influence of Socialization on Students' Knowledge Levels About Antibiotic Resistance in Selong District, East Lombok: Pengaruh Edukasi Terhadap Tingkat Pengetahuan Siswa Tentang Resistensi Antibiotik di Kecamatan Selong, Lombok Timur Risma Fatmayanti, Baiq; Ramadhan, Leny; Rafsanjani, Arief; Marlita, Jeli; Azim, Muhlisun; Febriani, Yuyun
Jukeshum: Jurnal Pengabdian Masyarakat Vol. 5 No. 2 (2025): Edisi Juli 2025
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/jukeshum.v5i2.1277

Abstract

Antibiotics are drugs used to treat bacterial infections. Irrational use of antibiotics without a doctor's prescription causes antibiotic resistance. West Nusa Tenggara province is ranked sixth with the largest number of antibiotic consumption without a doctor's prescription so the incidence of antibiotic resistance increases. This community service aims to provide antibiotic resistance education to high school students in Selong District. The community service method was carried out at SMAN 1 Selong and SMAN 2 Selong which started with pretest, socialization, and posttest activities to measure students' knowledge of antibiotic resistance before and after socialization. The significance test of changes in students' knowledge levels before and after socialization was conducted using a paired sample t-test. The socialization participants from SMAN 1 Selong and SMAN 2 Selong consisted of 141 high school students in grade XI with an average age of 16. The pretest and posttest data analysis showed that students' knowledge levels regarding antibiotic resistance increased from 41% to 59% at SMAN 1 Selong and 42% to 58% at SMAN 2 Selong after socialization. The average value of students' knowledge about antibiotic resistance increased from 10.04 points to 14.73 points for SMAN 1 Selong and 10.33 points to 14.16 points for SMAN 2 Selong after the socialization was given from a total of 17 maximum points that could be obtained. The results of data analysis using paired sample t-test showed a significant difference (p<0.05) in the average level of student knowledge before and after the socialization activity was carried out. Thus, the antibiotic resistance socialization activity has successfully increased student knowledge in Selong District, especially at SMAN 1 Selong and SMAN 2 Selong effectively.
Edukasi dan Pendampingan Pengelolaan Sampah Anorganik Berprinsip Zero Waste System di Desa Bagik Payung Selatan Kecamatan Suralaga Febriani, Yuyun; Azim, Muhlisun; Rafsanjani, Arief; Ramadhan, Leny; Risma Fatmayanti, Baiq
Jurnal Teknologi Informasi untuk Masyarakat Vol. 2 No. 1 (2024): Jurnal Teknologi Informasi untuk Masyarakat (Teknokrat)
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/jt.v2i1.26422

Abstract

Bagik Payung Selatan Village is one of the villages in Suralaga District, East Lombok Regency with a dense population of over 1.2 million people spread across 10 hamlets. The high population in Bagik Payung Selatan Village causes quite high amounts of waste production which can be seen from the large amount of rubbish piled up on the side of the road and environmental cleanliness still neglected. The community in Bagik Payung Selatan Village has a low level of awareness and knowledge regarding inorganic waste management. Most of the inorganic waste is plastic waste produced daily from household waste. This community service activity aims to provide education on inorganic waste management using ecobrick techniques with zero waste system principles in Bagik Payung Selatan Village so that the local community can manage inorganic waste well. The method of educating the community is carried out by providing outreach and training in skills to make handicraft products from inorganic waste which has previously been prepared using the ecobrick technique. The results of this community service activity include public knowledge and awareness regarding ecobrick techniques, the zero waste system principles, and community creativity in managing inorganic waste increased. The community is very enthusiastic about turning household waste into multiple useful handcraft products that can be reused and sold since they have high economic value to help the local community's economy.