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All Journal Biocelebes Borneo Journal of Pharmacy Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Amalia Purnamasari Zainal
Program Studi Farmasi, Fakultas Matermatika Dan Ilmu Pengetahuan Alam, Universitas Tadulako, Palu
Agriculture, Biological Sciences & Forestry Chemistry Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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FORMULASI MEDIA PERTUMBUHAN MISELIUM JAMUR TIRAM PUTIH (Pleurotus ostreatus (Jacq.) P. Kumm.) BERBAHAN DASAR DEDAK PADI DAN LIMBAH KOPI Umrah, Umrah; Triana, Nina Risnanda; Yuniati, Eny; Kasim, Amiruddin; Zainal, Amalia Purnamasari
Biocelebes Vol. 18 No. 1 (2024)
Publisher : Biology Department, Mathematics and natural science, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/bioceb.v18i1.17198

Abstract

Rice bran and coffee waste as a medium and source of nutrients needed for the growth of the white oyster mushroom mycelium (Pleurotus ostreatus (Jacq.) Kumm.). This research has been carried out at Microbiology Laboratory, Department of Biology, Faculty of Mathematics and Natural Sciences, Tadulako University. This study has almed : (1) To determine the growth of white oyster mushrooms (P. ostreatus (Jacq.) Kumm.) in the formulation of rice bran and coffee waste media. (2) Knowing the ratio in the media formulation of rice bran waste and coffee waste that can provide the best growth of white oyster mushroom (P.ostreatus (Jacq.) Kumm.). Data analysis research used in a completely randomized design (CRD), consisting of seven treatments and three replications, namely P1 (100% rice bran), P2 (95% rice bran + 5% coffee waste powder), P3 (90% rice bran + 10% coffee waste powder), P4 (85% rice bran + 15% coffee waste powder), P5 (80% rice bran + 20% coffee waste powder), P6 (75% rice bran + 25% coffee waste powder), P7 (sawdust 70% + rice bran 20% + corn flour 10% (positive control). The results showed that the best mycelium of growth were P7 and P1. The highest number of colonies were at treatment P7 1,26x1012CFU/gr and the lowest was P1 0,26x1012CFU/gr. The fastest incubation time was found in P7, which was 25 days and the lowest was in treatment was P6, 48 days.
KEGAGALAN PENGENDALIAN DIABETES MELLITUS TIPE II DITINJAU DARI FAKTOR PREDISPOSISI Khusnul Diana; Amalia Purnamasari Zainal; Setaiawati Fadhilah Zainal; Muhammad Rinaldhi Tandah; Dhea Puspita; Nurul Ambianti
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 10 No. 2 (2024): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v10i2.886

Abstract

Failure to control type II diabetes mellitus (DM) has a serious impact on the quality of life and health of DM patients. One of the factors that can influence the failure to control DM is predisposing factors. This study aims to determine predisposing factors including gender, education level, age, smoking, occupation, sports activities, long-suffering, knowledge, and behavior that influence failure to control type II DM. The research method used was descriptive analysis with cross-sectional data collection. This research used a purposive sampling technique and the patients used were 179 respondents. Data was collected using the Diabetes Knowledge Questionnaire (DKQ-24) questionnaire and the Self-Management Diabetes Mellitus (SMDM) questionnaire instrument. The data analysis used is bivariate and multivariate. The results of the bivariate analysis show that the variables that influence the failure to control Type II DM are the length of suffering (p = 0.000), behavior (p = 0.004), sports activities (p = 0.029), and work (p = 0.020). The results of the multivariate analysis of the dominant factors influencing failure to control type II DM are long-suffering with a value of OR = 6.956, behavior with a value of OR = 4.156, knowledge with a value of OR = 2.947, sports activities with a value of OR = 0.690, so it can be concluded that the variable long-suffering is The main factor in the failure to control type II DM because it can increase the risk of complications such as pancreatic cell damage and insulin resistance.
OBSERVASI PERTUMBUHAN SERTA PEMBENTUKAN TUBUH BUAH JAMUR TIRAM PUTIH (Pleurotus ostreatus) PADA MEDIA SERBUK GERGAJI DAN LIMBAH DAUN KAKAO Umrah, Umrah; Asfiani, Asfiani; Yuniati, Eny; Zainal, Amalia Purnamasari
Biocelebes Vol. 19 No. 1 (2025)
Publisher : Biology Department, Mathematics and natural science, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/bioceb.v19i1.17967

Abstract

he title of this research is The observation of the growth and formation of white oyster mushroom fruit body (Pleurotus ostreatus) on sawsdust and cocoa leaf waste media litter which has been carried out in the Microbiology Laboratory, Department of Biology, Faculty of Mathematics and Natural Sciences. The aim of this research is to determine mycelium growth and formation. Fruting bodies of white oyster mushrooms (Pleurotus ostreatus) on a basic medium of sawdust substituted with leaf litter cocoa. This research was designed in a Completely Randomized Design (CRD) consisting of seven treatments and three replications. The treatment media consisted of sawsdust and and cocoa leaf waste (CLW), namely P1 (sawsdust 500g without CLW), P2 (sawsdust 475g + CLW 25g), P3 (sawsdust 450g + CLW 50g), P4 (sawsdust 425g + CLW 75g), P5 (sawsdust 400g + CLW 100g), P6 (sawsdust 375g + CLW 125g), P7 (sawsdust 350g + CLW 150g) 45g rice bran + 5g lime + 500 ml water were added to each treatment. The best growth in observing the mycelium incubation period until it filled the baglog was in treatment (P2) with a time of 43 days, the best growth in the incubation period until pinheads appeared was in treatment (P1) with a time of 53 days, the best treatment for the number or fruit bodies is in treatment (P5) with a value of 8,67, the best treatment for fresh body weight fruit, namely treatment (P5) with a value of 60,67g. The best treatment for fruit body dry weight was treatment (P5) with a value of 11,33g. The media composition corresponds to the best treatment of the seven treatments, namely P5 (400g sawdust + 100g cocoa leaf litter). Because it has the fastest fruit body incubation. The highest number of fruit bodies and the heaviest fresh weight and dry weight.
Phytochemical Characterization and Antibacterial Potential of Ethanolic Extract of Durio zibethinus Murr. Albedo Ritha Pratiwi; Nadia Stevani; Syariful Anam; Amalia Purnamasari Zainal; Dyah Ratna Ayu Puspita Sari; Muhammad Azwar AR; Alyaan Siddiqui; Paula Mariana Kustiawan; Mahfuzun Bone; Wa Ode Sitti Musnina
Borneo Journal of Pharmacy Vol. 9 No. 3 (2026): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v9i3.11119

Abstract

Bacterial resistance to conventional antibiotics has become a major global health challenge, prompting the exploration of natural antibacterial agents derived from plant materials. Durian (Durio zibethinus Murr.) albedo, an abundant agricultural by-product, has received limited attention despite its potential as a source of bioactive compounds. This study aimed to determine the total phenolic and flavonoid contents of ethanolic durian albedo extract, characterize its functional groups using Fourier Transform Infrared (FTIR) spectroscopy, and evaluate its antibacterial activity against Staphylococcus aureus and Escherichia coli. Fresh albedo of the Montong cultivar was extracted by maceration using 96% ethanol. Total phenolic and flavonoid contents were determined using the Folin–Ciocalteu and aluminum chloride colorimetric methods, respectively. Functional groups were identified by FTIR spectroscopy, while antibacterial activity was assessed using the agar disc diffusion method at extract concentrations of 15%, 25%, 35%, and 45%. The extract contained 0.52 ± 0.06 mg GAE/g extract of total phenolics and 0.034 ± 0.001 mg QE/g extract of total flavonoids, indicating the predominance of phenolic compounds. FTIR analysis revealed characteristic functional groups associated with phenolic-rich phytochemicals, including hydroxyl, carbonyl, aromatic, and C–O groups. The extract exhibited concentration-dependent antibacterial activity, with the largest inhibition zones observed at 45% against S. aureus (15.6 ± 0.7 mm) and E. coli (12.4 ± 0.6 mm). The greater susceptibility of S. aureus suggests higher effectiveness against Gram-positive bacteria. These findings demonstrate that durian albedo possesses promising antibacterial potential associated with its phytochemical composition and support its valorization as a sustainable source of natural antibacterial agents.
Co-Authors Alyaan Siddiqui Amiruddin Kasim Asfiani, Asfiani Dhea Puspita Dyah Ratna Ayu Puspita Sari Eny Yuniati Khusnul Diana Mahfuzun Bone Muhammad Azwar AR Muhammad Rinaldhi Tandah Nadia Stevani Nurul Ambianti Paula Mariana Kustiawan Ritha Pratiwi Setaiawati Fadhilah Zainal Syariful Anam Triana, Nina Risnanda Umrah Umrah Wa Ode Sitti Musnina