Claim Missing Document
Check
Articles

DAYA HAMBAT INFUSA DAUN SAWO (MANILKARA ZAPOTA L.) TERHADAP BAKTERI ESCHERICHIA COLI Tandah, Muhamad Rinaldhi; Ibrahim, Nurlina; Diana, Khusnul; Ramdhani, Wirda Suci
Natural Science: Journal of Science and Technology Vol 4, No 2 (2015): Volume 4 Number 2 (August 2015)
Publisher : Univ. Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Penelitian ini bertujuan untuk mengetahui daya hambat infusa daun sawo (Manilkara zapota L.) dalam menghambat pertumbuhan bakteri Escherichia coli sebagai penyebab penyakit diare. Metode ekstraksi yang digunakan yaitu metode infudasi, dengan konsentrasi 25%, 50% dan 75% infusa daun sawo, aquadest sebagai kontrol negatif, dan kloramfenikol sebagai kontrol positif. Dilakukan replikasi sebanyak tiga kali pada setiap kelompok perlakuan. Metode pengujian daya hambat infusa daun sawo menggunakan sumuran pada media yang telah ditanam bakteri. Hasil penelitian menunjukan adanya zona hambat selama 24 jam dan tidak ditemukan zona hambat selama 2x24 jam pada ekstrak daun sawo. Hasil analisa menunjukkan bahwa rata-rata zona hambat yang dihasilkan secara berurutan pada konsentrasi 25%, 50%, dan 75% adalah 14,66 mm, 16,30 mm, dan 19,93 mm. Pada kontrol negatif tidak terbentuk zona hambat, sedangkan  pada kontrol positif rata-rata zona hambat sebesar 38,41 mm. Kesimpulan diperoleh bahwa ekstrak daun sawo dapat menghambat E. coli dengan KHM ekstrak daun sawo pada konsentrasi 25%, namun tidak dapat membunuh E. coli karena tidak ditemukan KBM ekstrak daun sawo terhadap bakteri E. coli.
KESESUAIAN PELAKSANAAN STANDAR PELAYANAN MINIMAL (SPM) BIDANG FARMASI DI INSTALASI FARMASI RUMAH SAKIT UNDATA PALU Faradillah, Nurul; Mukaddas, Alwiyah; Diana, Khusnul
Natural Science: Journal of Science and Technology Vol 6, No 2 (2017): Volume 6 Number 2 (August 2017)
Publisher : Univ. Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (234.721 KB)

Abstract

This study aims to determine the suitability of the implementation of the Pharmacy Minimum Service Standards in the hospital  at pharmacy section that includes: the length of service waiting time of compounded and available drugs, no error incident of drug administration and prescribing in refer to the formulation at the pharmacy installation, outpatient unit, in Undata Hospital, Palu. This study is a descriptive with quantitative data retrieval. Samples were prescription entered at the Undata hospital in the period from February to May 2016 including 12 sheets of cash prescription, 10 sheets of cash compounded prescription, 188 sheets of guarantee prescription and 187 sheets of guarantee compounded prescription. The results showed that the average length of services waiting time of cash prescriptions was 06 minutes 12 seconds, guarantee prescriptions was 07 minutes 01 seconds, cash compounded prescriptions was 17 minutes 02 seconds, guarantee compounded prescriptions was 16 minutes 05, no error incidence of drug administration was 100% and prescribing in refer to the formularium was 66.2%. These were in accordance to the standard of Kepmenkes RI No. 129 year 2008, except for prescribing in refer to the formularium. Therefore, it is suggested for drugs order should follow the hospital formularium 
PELAKSANAAN STANDAR PELAYANAN KEFARMASIAN DI APOTEK KOTA PALU Diana, Khusnul; Tandah, Muhamad Rinaldhi; Basuki, Muhamad
Jurnal Ilmiah As-Syifaa Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (386.586 KB) | DOI: 10.33096/jifa.v11i1.504

Abstract

 The standard of pharmaceutical service is a benchmark or guideline for parmacist in carrying out pharmaceutical service in pharmacy facilities, one of them is pharmacy, in order to realize optimal health in the community. This study aims to describe the implementation of standard pharmaceutical services at the pharmacy in Palu city. This study was an observational study with descriptive qualitative data, data collection was cross sectional with the total number of samples are 56 respondents pharmacists / pharmacy in Palu city. Data was collected using questionnaire sheets distributed to respondents. From the results of the study, the standard clinical pharmacy services performed by pharmacists in the form of prescription study activities (61.6%), dispensing (36.9%), counseling (52.5%). The standard of drug management, medical devices and medical disposable carried out by pharmacist (54.3%). Clinical service standards that were not implemented at the pharmacy in the form of drug information services (62.1%), monitoring drug therapy (78.3%) and monitoring drug side effects (89.9%).
Evaluasi Penggunaan Obat Berdasarkan Indikator Peresepan dan Pelayanan Pasien di Rumah Sakit Tora Belo Khusnul Diana; Aviva Kumala; Nina Nurlin; Muhamad Rinaldhi Tandah
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 7 No. 1SI (2020): Special Issue: Seminar Inovasi Teknologi dan Digitalisasi pada Pelayanan Kefa
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v7i1SI2020.13-19

Abstract

Pendahuluan: Praktik kefarmasian merupakan kegiatan terpadu untuk mengidentifikasi, mencegah serta menyelesaikan masalah yang berkaitan dengan obat dan kesehatan untuk  meningkatkan penggunaan  obat  yang rasional. Tujuan: Untuk mengevaluasi penggunaan obat berdasarkan indikator peresepan yang ditulis oleh dokter dan pelayanan pasien di RSUD Tora Belo, Kabupaten Sigi. Metode: Penelitian dilakukan secara retrospektif dan prospektif. Indikator peresepan digunakan untuk menghitung rata-rata jumlah obat, obat generik, antibiotik, suntik dan obat esensial/obat formularium rumah sakit yang tertera pada setiap lembar resep. Sampel resep diambil dari resep pasien umum rawat sebanyak 391 lembar dengan teknik purposive sampling, sedangkan indikator pelayanan pasien diambil dari pasien rawat jalan sebanyak 269 pasien dengan teknik accidental sampling. Hasil: Rata-rata penggunaan obat tiap lembar resep adalah 3,1 (standar: 1,8 - 2,2); persentase obat generik adalah 74,89% (standar: 81 - 94 %); persentase obat antibiotik adalah 45,52% (standar: ≤ 30%); persentase obat injeksi adalah 6,90% (standar: 0,2 - 48%); dan persentase kesesuaian obat dengan formularium rumah sakit adalah 99,17% (standar: 86 - 88%). Sedangkan dari indikator pelayanan pasien diperoleh rata-rata waktu konsultasi 4,32 menit (standar: 2,3 - 3,5 menit); rata-rata dispensing time obat non racikan 11, 42 dan racikan 22,54 menit; persentase obat yang diberikan 94,54% (standar: 100%); persentase kelengkapan label obat sebesar 100%; dan persentase pengetahuan pasien tentang penggunaan dosis yang tepat 48,12% (standar: 100%). Kesimpulan: Penggunaan obat belum memenuhi standar WHO jika dilihat dari indikator peresepan, namun masih memenuhi standar WHO jika dilihat dari indicator pelayanan.
ANALISIS BIAYA PENGOBATAN PENYAKIT GINJAL KRONIK RAWAT INAP DENGAN HEMODIALISIS DI RUMAH SAKIT UMUM DAERAH UNDATA PALU Muhamad Rinaldhi Tandah; Ihwan Ihwan; Khusnul Diana; Zulfiah Zulfiah; Nurul Ambianti
Jurnal LINK Vol 15, No 2 (2019): NOVEMBER 2019
Publisher : Pusat Penelitian dan Pengabdian kepada Masyarakat, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (196.006 KB) | DOI: 10.31983/link.v15i2.5222

Abstract

Penyakit Ginjal Kronik (PGK) merupakan masalah kesehatan global. Pembiayaan penyakit ginjal merupakan peringkat kedua terbesar dari BPJS kesehatan setelah penyakit jantung. Indonesia memasuki era Jaminan Kesehatan Nasional (JKN) sejak 01 Januari 2014. Pola pembayaran JKN adalah dengan sistem Indonesia Case Base Group (INA-CBGs). Penelitian ini bertujuan untuk mengetahui rata-rata biaya pengobatan, komponen biaya yang paling besar, serta selisih antara biaya pengobatan pasien PGK dengan JKN rawat inap terapi hemodialisis dengan standar tarif INA-CBGs. Penelitian ini merupakan penelitian deskriptif dengan pengumpulan data sekunder berupa biaya medik langsung dari perspektif rumah sakit pada pasien PGK rawat inap dengan JKN terapi hemodialisis di RSUD Undata Palu periode Januari - Desember 2017. Hasil penelitian menunjukan rata-rata biaya medik langsung pasien PGK rawat inap dengan hemodialisis sebesar Rp 11.074.834. Komponen biaya terbesar adalah biaya hemodialisis sebesar Rp 155.122.000  (37,86%) dari total pembayaran, dan selisih antara biaya medik langsung pasien PGK JKN rawat inap hemodialisis dengan standar tarif INA-CBGs sebesar Rp 191.920.841 (46,84 %) dari total biaya rumah sakit.
AKTIVITAS ANTIBAKTERI EKSTRAK KULIT BAWANG MERAH (Allium cepa L.) TERHADAP BAKTERI Staphylococcus aureus Misna Misna; Khusnul Diana
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 2 (2016): (October 2016)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (145.769 KB) | DOI: 10.22487/j24428744.2016.v2.i2.5990

Abstract

One of the plants tat used in medicine is garlic (Allium cepa L.). In addition as medicinal traditional plant, garlic is used as food spice. Garlic utillizated for the root only, and the skin which is rich with fibrous and flavonoid is wasted. This research aim is to know if the garlic skin have antibacterial activity against Staphylococcus aureus. Garlic skin made into extract with maseration methode using 96% ethanol. Antibacterial activity test with hollow diffusion methode. Te parameter used are inhibition zone created. Variation of concentration are 5%b/v, 10%b/v, 20%b/v, 40%b/v, 60%b/v, 80%b/v. Activity test made with extract added in the hole in the Staphylococcus aureus media, then incubated at temperature 370C 24 hours. The inhibition zone 5%, 10%, 20%, 40%, 60%, and 80% extract respectively were 7,00mm, 8,30mm, 9,60mm, 11,00mm, 12,33m and 14,33mm
UJI AKTIVITAS ANTIJAMUR INFUSA UMBI BAWANG PUTIH (Allium sativum L.) TERHADAP Candida albicans SERTA PROFIL KROMATOGRAFINYA Khusnul Diana
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 1 (2016): (March 2016)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (133.478 KB) | DOI: 10.22487/j24428744.2016.v2.i1.7087

Abstract

As traditional medicine, bawang putih or garlic ( Allium sativum L.) can cure as antibacterial and antifungal beside on can restorative as antihypertension, antacid, carminativa (in the dyspepsia), expectorancia and anticolesterol. This research was conducted in order to know the antifungal activity of infusion of Allium sativum against Candida albicans and to identify chemical component’s of this infusion. The antifungal activity was done by liquid dilution method. The MIC (Minimal Inhibitory Concentration) and MFC (Minimal Fungicidal Concentration) value were used as parameter to determine the antifungal activity. Concentration used in this reseach were 17,5%; 16,25%; 15%; 13,75% ; 12,5% dan 11,25% v/v for Candida albicans. The activity was done by incubating the infusion with fungal in CYG DS media of 37ºC for 18-24 hours. Identification of chemical component was carried out by paper chromatography and thin layer chromatography. The result showed that the MIC (Minimum Inhibitor Concentration) for Candida albicans could not be observed because the mixture was turbid. The MFC (Minimum Fungicidal Concentration) for Candida albicans was 15% v/v. The tube test and chromatogram showed that the infusion of Allium sativum contained flavonoid, and saponin.
Analisis Faktor-Faktor Yang Berpengaruh Terhadap Kinerja Balai Besar Pengawas Obat Dan Makanan Di Yogyakarta Dalam Menangani Kasus Makanan Bermelamin: Analysis of Factors Affecting Performance of National Agency of Drug and Food In Yogyakarta In Handling Melamine Containing Food Cases Khusnul Diana
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 3 No. 1 (2017): (March 2017)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.234 KB) | DOI: 10.22487/j24428744.2017.v3.i1.8141

Abstract

Melamine is not prohibited chemical to mix into food product. Around 2008, Melamine had found in baby milk which was made by China to make high protein level. To see BBPOM Yogyakarta’s performance handling of food which has contaminated of melamine, it is needed evaluation from customer’s satisfaction and affection of monitoring food contaminated melamine’s factors. In addition, it is necessary to know the gap between expectation and society’s perception. The study is descriptive explorative research. The study has done by giving performance questionnaire and the factor that affect to performance of employee at Investigation and Inspection sector in BBPOM Yogyakarta and qualitative analysis has done by interview. Based on the analysis result, personal/human resources, monitored system and infrastructure factors has not significance effect to BBPOM Yogyakarta performance handling contaminated food, because the monitoring has limited for withdrawing and scrapping product. From the interview result is known that there is an effect between personal/human resources, monitored system and infrastructures factors, because it is influenced by theoretical and subjectivity of respondent.
ANALISIS TINGKAT PENGETAHUAN DAN SIKAP TENAGA KEFARMASIAN DALAM MENCEGAH OBAT RUSAK DAN KADARLUARSA DI RSUD TORA BELO Nurul Ambianti; Muhamad Rinaldhi Tandah; Khusnul Diana; Ratu Balqis
Acta Pharmaciae Indonesia : Acta Pharm Indo Vol 9 No 2 (2021): Acta Pharmaciae Indonesia : Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2021.9.2.5135

Abstract

Abstract The defective and expired drugs are one of the problems that can reflect the inaccuracy and poor of drug management in a Hospital Pharmacy Unit (HPU). This research was conducted to determine the level of knowledge and attitudes of pharmaceutical personnel in preventing defective and expired drugs at the Regional General Hospital (RGH) Tora Belo. This type of researched is a non-experimental study with cross sectional data collection. The data used are primary data obtained from the results of questionnaires that have been filled out by pharmacist at Tora Belo Hospital. The analysis used in this study is correlation analysis using the Spearman-Rho test, to determine the relationship between the level of knowledge and attitudes of pharmaceutical personnel in preventing defective and expired drugs. The number of samples is 33 people taken by total sampling. Time to collect research data during May-October 2020. From the results of the study, it is known that the level of knowledge of the respondents is dominated by the sufficient category, namely 17 respondents (71.1%), it is known that the attitude of the respondents was included in the very strong category of 18 respondents (85.78%), and the results of the correlation analysis the relationship between the level of knowledge and attitudes of pharmaceutical personnel in preventing defective and expired drugs obtained a significance value of 0.021. So it can be concluded there is a relation between the level of knowledge and attitude of pharmaceutical workers in preventing defective and expired drugs at Tora Belo Hospital.
Tingkat Pengetahuan antara Mahasiswa Kesehatan dan Non Kesehatan terhadap Penggunaan Vitamin C di Universitas Tadulako Sulawesi Tengah Siti Mutmaina Ayu Lestari; Amelia Rumi; Khusnul Diana
Jurnal Health Sains Vol. 2 No. 5 (2021): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v2i5.165

Abstract

During the Covid-19 pandemic, it is recommended to use vitamin C in maintaining immunity, especially in students who have high activity. Widespread use can lead to dose abuse, resulting in side effects such as diarrhea, vomiting nausea to the formation of kidney stones. The purpose of this study was to determine the knowledge and use of vitamin C as well as the relationship between both medical and non-medical students of Tadulako University. This study used cross sectional method by collecting data through questionnaires in Google Form in 747 medical and non-medical students in the class of 2017-2019. Sampling techniques using purposive sampling. The results of the study obtained the knowledge of tadulako university medical students about vitamin C entered the sufficient category (47.01%) and non-medical students were included in the low category (59.01%). For the use of vitamin C, medical students fall into the high category (61.54%) and non-medical students were included in the sufficient category (48.74%). The results of the chi-square test, there is a significant relationship between knowledge and the use of vitamin C, with p value 0.000 (p value <0.05). The conclusion from the research, the knowledge of medical students about vitamin C and its use is better than non-medical students, and there is a link between the knowledge and use of vitamin C in tadulako university students.