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All Journal Natural Science: Journal of Science and Technology Biocelebes Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Pharmacology and Clinical Pharmacy Research Media Publikasi Penelitian Kebidanan Herbal Medicine Journal Metta: Jurnal Penelitian Multidisiplin Ilmu Jurnal Pengabdian Farmasi dan Sains
Nurlina Ibrahim
Program Studi Farmasi, Fakultas Matermatika Dan Ilmu Pengetahuan Alam, Universitas Tadulako, Palu
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health

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Antilithiatic Activity of Averrhoa bilimbi L. Leaves Ethanol Extract on White Mice (Mus musculus) Patala, Recky; Ibrahim, Nurlina; Khumaidi, Akhmad
Pharmacology and Clinical Pharmacy Research Vol 3, No 2 (2018)
Publisher : Universitas Padjadjaran, Indonesia

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Abstract

Nephrolithiasis refers to the formation of urinary calculi in the kidney and urogenital tract. It is associated with impairment of renal function. The leaves of Averrhoa bilimbi L are used empirically to treat abdominal pain, rheumatism, and to reduce kidney disorders symptoms. The aim of this study was to identify antilithiatic activity of ethanol extract of A. bilimbi L. leaves by determining the kidney weight changes and calcium levels in kidney extract of mice using Atomic Absorption Spectrophotometry (AAS) at 422.7 nm. A total of 18 male mice were included and classified into 5 groups, i.e., positive control, negative control, and extract at 16.6; 25; and 33 mg/kg BW.  Result showed that the calcium levels of the A. bilimbi L. extract groups were significantly lower than the control group (p<0.05). The most effective dose was 16.6 mg/kg BW. In conclusion, the leaves ethanol extract of A. bilimbi L. possessed antilithiatic activity.Keywords: Averrhoa bilimbi L., antilithiatic activity, calcium levels, kidney stones, renal impairment
ANALISIS LOGAM TIMBAL (PB) PADA IKAN PETEK (LEIOGNATHUS SP.) DAN IKAN TERI (STELOPHORUS SP.) DI KAWASAN LAUT TELUK PALU SECARA SPEKTROFOTOMETRI SERAPAN ATOM Hasrat, Hasrat; Jamaluddin, Jamaluddin; Ibrahim, Nurlina
Natural Science: Journal of Science and Technology Vol 3, No 3 (2014): Volume 3 Number 3 (December 2014)
Publisher : Univ. Tadulako

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Abstract

Penelitian ini bertujuan untuk mengetahui adanya cemaran logam Timbal (Pb) dan jumlah cemarannya pada spesies ikan Petek dan ikan Teri di kawasan laut Teluk Palu. Metode yang digunakan adalah destruksi kering (dry ashing) kemudian dianalisis secara kualitatif menggunakan pereaksi : (1) KCN ditambah Ditizon 0,005%, (2) Serbuk KI dan (3) Serbuk Na2CO3, serta uji kuantitatif dengan metode Spektrofotometri Serapan Atom pada ?maks 217 nm. Hasil penelitian didapatkan bahwa pada pengujian kualitatif ikan positif mengandung logam timbal (Pb). Hasil pengujian kuantitatif didapatkan kadar rata-rata logam timbal (Pb) adalah : (1) Ikan Petek di lokasi Taman Ria 0,757 mg/kg ; (2) Ikan Petek di lokasi sekitar Muara Sungai Palu 1,752 mg/kg ; (3) Ikan Petek di lokasi sekitar Pantai Talise 0,719 mg/kg ; (4) Ikan Teri di lokasi Taman Ria 1,989 mg/kg ; (5) Ikan Teri di lokasi sekitar Muara Sungai Palu 2,075 mg/kg  dan (6) Ikan Teri di lokasi sekitar Pantai Talise 1,655 mg/kg. Kadar logam timbal (Pb) pada kedua ikan tersebut telah melampaui nilai batas maksimum berdasarkan SNI 7387:2009 yaitu 0,3 mg/kg.
STANDARISASI EKSTRAK ETIL ASETAT KAYU SANREGO (LUNASIA AMARA BLANCO) Anam, Syariful; Yusran, Muhammad; Trisakti, Alfred; Ibrahim, Nurlina; Khumaidi, Ahmad; Ramdanil, Ramdanil; Zubair, Muhammad Sulaiman
Natural Science: Journal of Science and Technology Vol 2, No 3 (2013): Volume 2 Number 3 (December 2013)
Publisher : Univ. Tadulako

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Abstract

Lunasia amara Blanco is a popular medicinal plant which is known as aphrodisiac in South Sulawesi Province. Biological activity as antibacterial, anticancer dan antituberculosis were also scientifically reported. This study is to ascertain the safety and quality of the plant extract by standardization procedures mentioned in literature, including specific and non-specific parameters. The result showed that ethyl acetate wood extract of L. amara Blanco, which is brown viscous extract, astringent to the taste and characteristic odor, contain water-soluble extractive matters of 23,95 ± 2,192 %, ethanol-soluble extractive matters of 67,05 ± 3,61 %, water content of 5,33 ± 0,407 %,  total ash content of 0,65 ± 0,199 %, acid-insoluble ash content of 0,58 ±0,225 %, density of 0,7734 ± 0,0016 (5%) and 0,7957 ± 0,0021 (10%), total contaminant number of bacteria and fungus of each < 1 x 104 colony/g, and Pb concentration of 10,59 ± 0,239 mg/kg. Ethyl acetate wood extract of L. amara Blanco has been qualified as standardized extract. Therefore, this study can be a reference for identification and control quality of the extract as a herb-medicine material
PENDUGAAN MASA SIMPAN LIKOPEN BUAH TOMAT AFKIRAN (LYCOPERSICUM ESCULENTUM MILL) TERSALUT MALTODEKSTRIN DALAM KEMASAN KAPSUL PADA BERBAGAI SUHU PENYIMPANAN Sumarni, Ni Ketut; Mappiratu, Mappiratu; Ibrahim, Nurlina; Diharnaini, Diharnaini; Khaerunisa, Khaerunisa
Natural Science: Journal of Science and Technology Vol 5, No 1 (2016): Volume 5 Number 1 (March 2016)
Publisher : Univ. Tadulako

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Abstract

Upaya untuk mendapatkan keterangan tentang masa simpan likopen dari buah tomat tersalut maltodekstrin dalam kemasan kapsul dilakukan melalui penyalutan ekstrak likopen dengan maltodekstrin pada berbagai rasio ekstrak likopen terhadap maltodekstrin, dilanjutkan dengan pengemasan dalam kapsul, likopen tersalut maltodekstrin terbaik dilakukan penyimpanan pada suhu 40 dan 50oC. Pengamatan terhadap kerusakan likopen dilakukan setiap 24 jam selama 240 jam. Hasil pengamatan bentuk dan kadar likopen tersalut maltodekstrin menunjukkan bentuk tersalut terbaik terdapat pada rasio likopen/maltodekstrin 1 : 1 atas dasar berat perberat, dan pada rasio tersebut kadar likopen likopen tersalut maltodekstrin 45,47%. Kerusakan likopen tersalut maltodekstrin dalam kemasan kapsul mengikuti reaksi orde nol. Dengan menggunakan asumsi masa kadaluarsa likopen tersalut maltodekstrin dalam kemasan kapsul pada tingkat kerusakan 70 %, diperoleh waktu simpan likopentersalut maltodekstrin dalam kemasan kapsul pada suhu 40 dan 50oC masing-masing 926 hari dan 488 hari. Berdasarkan nilai masa simpan pada suhu 40 dan 50oC tersebut diperoleh faktor percepatan reaksi atau nilai Q10 sebesar 1,9. Dengan menggunakan nilai Q10, diperoleh waktu simpan likopen tersalut maltodekstrin dalam kemasan kapsul pada suhu penyimpanan 20, 25, 30 dan 35oC masing-masing 3.341 hari, 2.427 hari, 1.759 hari dan 1.277 hari.
DAYA HAMBAT INFUSA DAUN SAWO (MANILKARA ZAPOTA L.) TERHADAP BAKTERI ESCHERICHIA COLI Tandah, Muhamad Rinaldhi; Ibrahim, Nurlina; Diana, Khusnul; Ramdhani, Wirda Suci
Natural Science: Journal of Science and Technology Vol 4, No 2 (2015): Volume 4 Number 2 (August 2015)
Publisher : Univ. Tadulako

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Abstract

Penelitian ini bertujuan untuk mengetahui daya hambat infusa daun sawo (Manilkara zapota L.) dalam menghambat pertumbuhan bakteri Escherichia coli sebagai penyebab penyakit diare. Metode ekstraksi yang digunakan yaitu metode infudasi, dengan konsentrasi 25%, 50% dan 75% infusa daun sawo, aquadest sebagai kontrol negatif, dan kloramfenikol sebagai kontrol positif. Dilakukan replikasi sebanyak tiga kali pada setiap kelompok perlakuan. Metode pengujian daya hambat infusa daun sawo menggunakan sumuran pada media yang telah ditanam bakteri. Hasil penelitian menunjukan adanya zona hambat selama 24 jam dan tidak ditemukan zona hambat selama 2x24 jam pada ekstrak daun sawo. Hasil analisa menunjukkan bahwa rata-rata zona hambat yang dihasilkan secara berurutan pada konsentrasi 25%, 50%, dan 75% adalah 14,66 mm, 16,30 mm, dan 19,93 mm. Pada kontrol negatif tidak terbentuk zona hambat, sedangkan  pada kontrol positif rata-rata zona hambat sebesar 38,41 mm. Kesimpulan diperoleh bahwa ekstrak daun sawo dapat menghambat E. coli dengan KHM ekstrak daun sawo pada konsentrasi 25%, namun tidak dapat membunuh E. coli karena tidak ditemukan KBM ekstrak daun sawo terhadap bakteri E. coli.
STUDI TANAMAN BERKHASIAT OBAT SUKU MORI DI KECAMATAN PETASIA, PETASIA BARAT, DAN PETASIA TIMUR KABUPATEN MOROWALI UTARA SULAWESI TENGAH Idris Idris; Nurlina Ibrahim; Arsa Wahyu Nugrahani
Biocelebes Vol. 12 No. 1 (2018)
Publisher : Biology Department, Mathematics and natural science, Tadulako University

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Abstract

This study aims to conduct an inventory, knowing how to use and organs of plants used as medicine by Mori Tribal in Petasia, Petasia and East Petasia District, West North Morowali Regency of Central Sulawesi. This study used qualitative methods and sampling techniques that snowball sampling, with open-ended interview techniques interview on media 9 informants obtained using a questionnaire. Based on the results of research known as 79 species of medicinal plants, 2 of which can not be identified and divided into 45 familia used as a medicine. Plants are most widely used is of familia Euphorbiaceae as many as 8 species. Organs of plants used include leaves, stems, fruits, rhizomes, seeds, bark, flowers, bulbs, herbaceous roots and sap. Organ plant is widely used is the leaves that percentage utilization is 58%. Mori Tribal communities in the District, West Petasia and East Petasia North Morowali District use medicinal herbs to treat the disease, healing and health maintenance. The cooking methods include boiling water, brewed, boxed, taped, squeezed, scrubbed/smeared, chewed and consumed directly, drops, and sprayed. How to use include drunk, eaten, chewed and consumed directly, polished/smeared, attached, dropped, and chewed and sprayed on the affected area.
Uji Aktivitas Antibakteri Ekstrak Serbuk Gergaji Kayu Eboni (Diospyros celebicaBakh.) Terhadap Bakteri Staphylococcus aureus dan Escherichia coli Wahyuni Wahyuni; Nurlina Ibrahim; Arsa Wahyu Nugrahani
Biocelebes Vol. 12 No. 1 (2018)
Publisher : Biology Department, Mathematics and natural science, Tadulako University

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Abstract

Ebony (Diospyros celebica Bakh.) is one of the beneficial plants from ebenaceae, especially in traditional medicine. The sawdust extract containing chemical compounds such as tannins, saponins and terpenoids. This research were aimed to determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) also to identified the active compounds from sawdust extracts of D. celebica Bakh. against Staphylococcus aureus and Escherichia coli. The Research methods include extraction using maceration method by ethanol 96%. MIC and MBC determination using dilution and diffusion methods. The Results showed that MIC value of S.aureus and E. coli were 6% and 7%, respectively. While MBC value of S. aureus and E. coli were 12% and 13%, respectively. Identification of chemical compounds were determined by Thin Layer Chromatography (TLC) bioautography method by 10% H2SO4 and anisaldehid-sulfuric acid reagent spray. There were two chemichal compounds that produced, saponin and terpenoid.
ETNOBOTANI SUKU TOGIAN DI PULAU MALENGE KECAMATAN TALATAKO, KABUPATEN TOJO UNA-UNA, SULAWESI TENGAH Dalton Fidel Tabeo; Nurlina Ibrahim; Arsa Wahyu Nugrahani
Biocelebes Vol. 13 No. 1 (2019)
Publisher : Biology Department, Mathematics and natural science, Tadulako University

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Abstract

Ethnobotany study in Togian Tribe has done in Tojo Una-Una, Central Sulawesi. This study was aimed to find out the information about the types of plants, used parts, processing, usage and dosage as well as knowing what type of disease treated using medicinal plants by Togian tribal communities in Malenge Island, Talatako District, Tojo Una- una, Central Sulawesi. This research  was a descriptive study with qualitative methods and used snowball sampling through interviews on four informants with the questionnaire. The results showed that 60 species are divided into 33 families. the most widely used was the Asteraceae by 7 species and Fabaceae familia by 6 species. Plant parts include leaves, stems, fruit, roots, rhizomes, herbs, seeds, sap and flowers partnered with the largest percentage of leaves 56%. the using and processing of medicinal plants by the Togian Tribe Malenge Island were boiled, mashed, squeezed, shredded, soaked, drunk, chewed, dropped, scrubbed, and pasted. the most  using and processing were boiled and drunk.
STUDI TUMBUHAN BERKHASIAT OBAT PADA SUKU KAILI DA’A KECAMATAN KINOVARO KABUPATEN SIGI SULAWESI TENGAH Sri Rizqi Muthmainnah; Nurlina Ibrahim; Ririen Hardani
Biocelebes Vol. 12 No. 2 (2018)
Publisher : Biology Department, Mathematics and natural science, Tadulako University

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Abstract

Study of medicinal plants on Kaili Da’a tribe at Kinovaro district, Sigi Regency in Central Sulawesi has been done to preserve the knowledge and use of herbs for traditional medicine. This study aims to determine the type of plants used as medicine, the type of disease being treated as well as how to use these plants by Da'a tribe. This research is a descriptive study using qualitative methods with a sampling technique that snowball sampling through interviews and direct observation of 7 respondents of Kaili Da'a tribe. Based on the interview, known as much as 31 families of medicinal plants. The results of identification of the plants used as medicines known 65 species, 6 species which have been unidentified its species (2 species unidentified families). The most widely used plant is from Euphorbiaceae family (6 species). Parts of plants used include leaves, stems, fruits, roots, herbs, seeds, sap and flowers. The leaves are part of plants that have the highest usage percentage (77%). As for how to use of medicinal plants is done by mouth, chewed, spilled, smeared, taped, wrapped, dyed and used in massage. How to use the most that drunk as much as 70%.
STUDI PERBANDINGAN PROFIL ASAM LEMAK PADA IKAN SIDAT (Anguilla marmorata) DAN SIDAT (Anguilla bicolor) ASAL DANAU POSO KABUPATEN POSO PROVINSI SULAWESI TENGAH Dewi Muhtiani; Nurlina Ibrahim; Jamaluddin Jamaluddin
Biocelebes Vol. 14 No. 1 (2020)
Publisher : Biology Department, Mathematics and natural science, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/bioceb.v14i1.15089

Abstract

Sidat fish (Anguilla marmorata) and Sidat fish (Anguilla bicolor) originate from Poso lake are endemic fish of Central Sulawesi but unknown its nutritional content. This study aims to determine the type, amount of composition and differences in the composition of fatty acids in Sidat fish (Anguilla marmorata) and Sidat fish (Anguilla bicolor). Testing fatty acid composition using Gas Chromatography method by converting fat extraction result into FAME (Fatty Acid Methyl Ester) form. The results showed that the amount of fatty acid content was not significant between the two samples. The fatty acid compositions found in Sidat (Anguilla marmorata) A, B and C fish include saturated fatty acids (2.62%), (2.81%), and (2.6%), monounsaturated fatty acids (1.98% ), (1.99%), and (10.1%), compound unsaturated fatty acids (0.635%), (0.812%), and (2.56%), mean while Sidat fish (Anguilla bicolor) A, B and C include saturated fatty acids (2.7%), (2.86%), and (12.704%), monounsaturated fatty acids (1.99%), (2.52%), (10.147%), and fatty acids unsaturated compounds (0.693%), (0.86%), and (2.615%).
Co-Authors Agustinus Widodo Ahmad Khumaidi Akhmad Khumaidi Alfred Trisakti Andi Riesti Angelin Peuru atyrah andi Budiarti, Suci Dalton Fidel Tabeo Dewi Muhtiani Diharnaini Diharnaini Evi Sulastri Hasrat Hasrat Hermin Hermin Idris Idris Jamaluddin Jamaluddin Jamaluddin Jamaluddin Khaerunisa Khaerunisa, Khaerunisa Khusnul Diana Mappiratu Mappiratu Masyita, Andi Atirah Muhamad Rinaldhi Tandah Muhammad Sulaiman Zubair Muhammad Yusran Muhammad Yusuf Islami Nela Sharon Ni Ketut Sumarni Pettalolo, Nur Bahra Purnamasari Zainal, Amalia Ramdanil Ramdanil Recky Patala Ririen Hardani Sativa, Oriza Siti Helmyati Sri Rizqi Muthmainnah Syariful Anam Upik Rohaya Wa Ode Irma Indrayangingsih Wirda Suci Ramdhani, Wirda Suci Wiwik Handayani Yonelian Yuyun