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All Journal Jurnal Farmasi SYIFA Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Jurnal Etnofarmasi
Ivan Charles S.Klau
Universitas Anwar Medika
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology Nursing Public Health

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REVIEW JURNAL : STUDI ETNOFARMASI TERHADAP PEMANFAATAN BAWANG PUTIH (Allium sativum) SEBAGAI TERAPI HERBAL HIPERTENSI Nisful Lailatun Nadiroh; Dwi Roisiyah; Nailah Mutiara Wahid; Nungki Hatit Isafani; Jesika Diah Pitaloka; Iftitah Nakhlah Sani; Wishnu Eka Adiwinata; Muhammad Rizky Imami; Farrel Darian Hafiz Fathan; Ivan Charles S.Klau
JURNAL ETNOFARMASI Vol. 3 No. 02 (2025): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v3i02.2690

Abstract

Hypertension, or high blood pressure, is a chronic medical condition characterized by an increase in systolic blood pressure ≥140 mmHg and/or diastolic ≥90 mmHg based on two measurements at rest. In the treatment of hypertension, in addition to pharmacological treatment, complementary therapy approaches based on medicinal plants are starting to gain attention because they are considered safer. Garlic is one of the most widely studied because of its bioactive compound content which has pharmacological activity, including in lowering blood pressure and as a natural antioxidant. The review was conducted using the method of collecting several national research journals and previously published literature. The sources used in this journal review are several journals that have been accredited by SINTA and also literature from the last 5 years. The search for articles and research journals was carried out using article search engines such as PubMed, ResearchGate, Google, and Google Scholar. The journal review conducted this time aims to see and find out how much potential the garlic plant has to act as an antihypertensive. The sources used in this review are journals that have been accredited. The results of several literature studies found that there was an effect of giving garlic herbal medicine to hypertension sufferers. The conclusion is that giving garlic infusion can lower blood pressure in hypertension patients.
REVIEW JURNAL : STUDI ETNOFARMASI TERHADAP PEMANFAATAN BAWANG PUTIH (Allium sativum) SEBAGAI TERAPI HERBAL HIPERTENSI Nisful Lailatun Nadiroh; Dwi Roisiyah; Nailah Mutiara Wahid; Nungki Hatit Isafani; Jesika Diah Pitaloka; Iftitah Nakhlah Sani; Wishnu Eka Adiwinata; Muhammad Rizky Imami; Farrel Darian Hafiz Fathan; Ivan Charles S.Klau
JURNAL ETNOFARMASI Vol. 3 No. 02 (2025): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v3i02.2690

Abstract

Hypertension, or high blood pressure, is a chronic medical condition characterized by an increase in systolic blood pressure ≥140 mmHg and/or diastolic ≥90 mmHg based on two measurements at rest. In the treatment of hypertension, in addition to pharmacological treatment, complementary therapy approaches based on medicinal plants are starting to gain attention because they are considered safer. Garlic is one of the most widely studied because of its bioactive compound content which has pharmacological activity, including in lowering blood pressure and as a natural antioxidant. The review was conducted using the method of collecting several national research journals and previously published literature. The sources used in this journal review are several journals that have been accredited by SINTA and also literature from the last 5 years. The search for articles and research journals was carried out using article search engines such as PubMed, ResearchGate, Google, and Google Scholar. The journal review conducted this time aims to see and find out how much potential the garlic plant has to act as an antihypertensive. The sources used in this review are journals that have been accredited. The results of several literature studies found that there was an effect of giving garlic herbal medicine to hypertension sufferers. The conclusion is that giving garlic infusion can lower blood pressure in hypertension patients.
Artikel Review Fitokimia : Efektivitas Maserasi Soxhletasi sebagai Metode Ekstraksi Miftakhul Rokhmah; Amanda Rafina Modesty; Auliya Ika Putri; Salsabiila Wina Delia; Adelia Girlani Bria; Maria Delsiana Ndun; Elsa Tectona Zuliyanti; Renata Setya Agustin; Petrus Paulus Bria; A’Yunil Hisbiah; Ivan Charles S.Klau; Arista Wahyu Ningsih
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2060

Abstract

The Soxhlet extraction method uses repeated heating and solvent circulation to separate substances from mixtures, producing more extract faster than maceration with less solvent. However, this method requires pure solvents and is not suitable for thermolabile compounds as they can be degraded by heat. Soxhlet extraction is more effective for limited quantities of dry and fine herbal materials. This method is widely used to extract phytochemical compounds such as flavonoids, tannins, and curcumin, and has potential in cosmetic raw materials, herbal medicines, and antioxidant products. Although it uses more energy, this technique is efficient and continuous. Modern innovations such as combining it with Ultrasonic Assisted Extraction (UAE) or environmentally friendly microextraction are expected to increase extraction efficiency while reducing the use of organic solvents. Modifications to Soxhlet, including automation and assistive technologies such as high pressure, ultrasound, and microwaves, open up opportunities for commercialization and further research with more optimal results and more practical operations. The modified Soxhlet is considered a “panacea” in extraction due to the significant performance improvements achieved.
Artikel Review Fitokimia: Efektifitas Dekokta Sebagai Metode Ekstraksi Novita Fitriana Ikfar; Fina Salsabila Nur Aini; Seylin Zavira Ananta; Anisa Khanif Khusnia; Wilda Tsabitah Jafnah Mahmud; Najwa Firida Rahma; Salsha Bila Dwi Lestari; Angelita Maulya Cantika Putri; Alya Miladiyah Chayani; A’Yunil Hisbiah; Ivan Charles S.Klau; Arista Wahyu Ningsih
Jurnal Farmasi SYIFA Vol 4 No 1 (2026): Jurnal Farmasi SYIFA
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/jfs.v4i1.862

Abstract

Dekokta merupakan salah satu metode ekstraksi konvensional yang banyak digunakan dalam pengolahan tanaman obat karena prosesnya sederhana, efektif, dan mampu menghasilkan senyawa bioaktif dalam jumlah tinggi. Penelitian dan pengembangan mengenai metode ini bertujuan untuk mengeksplorasi kemampuannya dalam mengekstraksi senyawa aktif serta mengevaluasi aktivitas biologis dari berbagai tanaman obat. Proses dekokta dilakukan dengan merebus simplisia tanaman dalam air pada suhu dan waktu tertentu untuk mengekstraksi komponen aktif, dan telah diterapkan pada berbagai tanaman seperti daun iler, daun singkong, krokot, Gracilaria verrucosa, daun mengkudu, serta sabut kelapa muda. Hasil penelitian menunjukkan bahwa metode ini mampu mengekstraksi senyawa penting seperti flavonoid, tanin, polifenol, alkaloid, saponin, dan terpenoid, menghasilkan rendemen serta kadar fenolik yang tinggi, dan menunjukkan aktivitas biologis signifikan seperti antibakteri terhadap Staphylococcus aureus dan Escherichia coli, aktivitas antioksidan kuat, serta aktivitas antiinflamasi dengan nilai IC₅₀ yang kompetitif terhadap kontrol positif. Selain itu, dekokta juga berperan dalam pembentukan supramolekul dan partikel nano homogen yang meningkatkan efektivitas fitokimia, seperti pada Mahuang Fuzi Decoction (MGF). Dengan berbagai keunggulan tersebut, dekokta menjadi metode penting dalam pengembangan obat herbal modern dan berpotensi menjadi dasar inovasi untuk meningkatkan stabilitas, bioaktivitas, serta nilai komersial produk fitofarmaka.
Co-Authors Adelia Girlani Bria Alya Miladiyah Chayani Amanda Rafina Modesty Angelita Maulya Cantika Putri Anisa Khanif Khusnia ARISTA WAHYU NINGSIH Auliya Ika Putri A’Yunil Hisbiah Dwi Roisiyah Elsa Tectona Zuliyanti Farrel Darian Hafiz Fathan Fina Salsabila Nur Aini Iftitah Nakhlah Sani Jesika Diah Pitaloka Maria Delsiana Ndun Miftakhul Rokhmah Muhammad Rizky Imami Nailah Mutiara Wahid Najwa Firida Rahma Nisful Lailatun Nadiroh Novita Fitriana Ikfar Nungki Hatit Isafani Petrus Paulus Bria Renata Setya Agustin Salsabiila Wina Delia Salsha Bila Dwi Lestari Seylin Zavira Ananta Wilda Tsabitah Jafnah Mahmud Wishnu Eka Adiwinata