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All Journal Indonesian Journal of Health Science Jurnal Sehat Indonesia (JUSINDO) The Journal General Health and Pharmaceutical Sciences Research
Anna Uswatun Hasanah Rochjana
Institut Kesehatan Hermina
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary Other

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Uji Efek Antikoagulan Dari Ekstrak Etanol Kembang Sepatu Sungsang (Hibiscus Schizopetalus (Mast) Hook.F) Anna Uswatun Hasanah Rochjana; Ilham Maulana
Jurnal Sehat Indonesia (JUSINDO) Vol. 6 No. 01 (2024): Jurnal Sehat Indonesia (JUSINDO)
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v6i01.74

Abstract

Penelitian ini membahas potensi antikoagulan dari ekstrak etanol daun kembang sepatu sungsang (Hibiscus schizopetalus (Mast) Hook.F) sebagai pengobatan herbal untuk penyakit kardiovaskular. Pengobatan herbal telah terbukti efektif dalam mengatasi penyakit sulit sembuh seperti kanker dan kelumpuhan, dengan keunggulan bahan dasar alami yang mengurangi efek samping. Fokus penelitian adalah pada kandungan senyawa bioaktif, seperti flavonoid, triterpenoid, tannin, steroid, dan glikosida, dalam daun kembang sepatu sungsang. Melalui metode cross-sectional dan pengujian terhadap ekstrak dengan konsentrasi 2%, 4%, dan 6%, hasil penelitian menunjukkan bahwa ekstrak dengan konsentrasi 6% memberikan efek antikoagulan yang optimal. Temuan ini memiliki kontribusi ilmiah penting dalam pengembangan pengobatan herbal sebagai alternatif untuk mencegah penyakit kardiovaskular, dengan menyimpulkan bahwa ekstrak etanol daun kembang sepatu sungsang memiliki potensi antikoagulan dengan tingkat efektivitas yang meningkat seiring dengan peningkatan konsentrasi ekstrak.
Tingkat Pengetahuan Masyarakat Mengenai Penggunaan Obat Antihipertensi Golongan Calcium Channel Blocker (Amlodipine) di RT 006 RW 03 Kelurahan Johar Baru Jakarta Pusat Sakilah Alaisah Astuti; Anna Uswatun Hasanah Rochjana; Milda Rianty Lakoan
The Journal General Health and Pharmaceutical Sciences Research Vol. 3 No. 3 (2025): September :The Journal General Health and Pharmaceutical Sciences Research
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/tjghpsr.v3i3.868

Abstract

Hypertension is defined as a systolic blood pressure greater than 120 mmHg and a diastolic blood pressure greater than 80 mmHg, measured twice within 5 minutes during rest. If left untreated, hypertension can lead to kidney and heart damage and increase the risk of stroke. This study aims to assess the community's knowledge regarding the use of antihypertensive medication, specifically the calcium channel blocker (amlodipine), in RT 006 RW 03 Kelurahan Johar Baru, Central Jakarta. The study involved 50 participants aged 17-64 years with a history of hypertension. A descriptive quantitative method was used, with data collected through questionnaires and analyzed using SPSS. The results show that 83% of the participants had good knowledge about hypertension, 76% had good knowledge about the dosage of amlodipine, 76% had good knowledge about the correct administration of amlodipine, and 50% had sufficient knowledge about the side effects of the drug. The average knowledge level based on the indicators was 71%, which is categorized as adequate.
Patterns of antithyroid drug use in hyperthyroid patients at the outpatient pharmacy of hospital x from January to December 2023 Rif'aa Naflah Faadiyah; Sylvi Adiana; Anna Uswatun Hasanah Rochjana
Indonesian Journal of Health Science Vol 6 No 1 (2026)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v6i1.1788

Abstract

Hyperthyroidism is a condition characterized by increased production and secretion of thyroid hormones by the thyroid gland. This condition is indicated by a significant increase in triiodothyronine (T3) and thyroxine (T4) levels, which is generally caused by an autoimmune response that attacks the thyroid gland. This study aims to determine the pattern of use of hyperthyroid drugs based on medical record data and outpatient BPJS prescriptions at Hospital X during the period January to December 2023. This research is an observational study with a quantitative approach using descriptive methods, and data collection is done retrospectively. Results based on patient characteristics based on age, dominated by the age group with a range of 26-35 years as many as 56 people (29.47%) and gender dominated by women as many as 148 people (77.89%). Results based on the pattern of use of antithyroid drugs in hyperthyroid patients show that based on the type of drug, propylthiouracil (PTU) is more widely used in patients with hyperthyroidism as much as 124 uses (65.26%) and the class of drugs used in hyperthyroid patients with Thionamide group, obtained a percentage of 100%.
The effect of ethanol extract of Wuru Ketek Leaves (Myrica javanica Reinw. ex Bl.) on the relative weight of organs in Male White Mice (Mus musculus L.) with alloxan-induced diabetes. Anna Uswatun Hasanah Rochjana; Varda Arianti; Devi Maulina; Fani Aprilia
Indonesian Journal of Health Science Vol 6 No 2 (2026)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v6i2.2151

Abstract

Wuru Ketek (Myrica javanica Reinw. ex Bl.) plant is known to contain flavonoids and tannins that have the potential as antidiabetics. This study aims to evaluate the effect of ethanol extract of wuru ketek leaves (Myrica javanica Reinw. ex Bl.) on the relative weight of the liver, kidneys, and heart of alloxan-induced diabetic male mice. A total of 30 mice were divided into six groups: normal group, negative control, positive control (glibenclamide), and three treatment groups with doses of 100, 200, and 300 mg/kgBW for 12 days orally. The organs were weighed and analyzed statistically. The results showed no significant difference in relative organ weight (p>0.05) between the treatment group and the normal group. These findings indicate that the ethanol extract of wuru ketek leaves (Myrica javanica Reinw. Ex Bl.) does not show toxic effects on target organs in the short term. Further studies are needed to assess long-term safety and other biochemical parameters.
The effect of education on the level of knowledge regarding the disposal of expired medications among the community of Cipinang Muara Dhega Rhefaldy Dermawan; Anna Uswatun Hasanah Rochjana; Amalina Fakhriah
Indonesian Journal of Health Science Vol 6 No 4 (2026)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v6i4.2385

Abstract

Improper disposal of expired medication remains a community issue that poses potential risks to health and the environment, particularly when conducted without appropriate pharmaceutical waste management procedures. This study aimed to determine the impact of education on the community's level of knowledge regarding the disposal of expired medication in Cipinang Muara (RT 06 and RT 07, RW 04), East Jakarta. A pre-experimental, one-group pre-test/post-test design with a cross-sectional approach was employed. A sample of 72 respondents was selected using purposive sampling. Data were collected via a questionnaire that had undergone validity and reliability testing. A Shapiro-Wilk normality test revealed that the pre-test data were normally distributed, whereas the post-test data were not; consequently, the Wilcoxon Signed-Rank Test was used for analysis. The results indicated that prior to the educational intervention, knowledge levels fell predominantly into the "poor" (48.61%) and "fair" (19.44%) categories, with 31.95% falling into the "good" category. Following the intervention, all respondents (100%) were classified in the "good" category. The Wilcoxon Signed-Rank Test yielded a significance value of 0.000 (p < 0.05), indicating a significant difference in knowledge levels before and after the education. Thus, the educational intervention was effective in increasing community knowledge regarding the disposal of expired medication. These findings underscore the importance of continuous educational programs as a preventive measure to support safe household pharmaceutical waste management for the benefit of health and the environment.
The effect of education on the level of public knowledge regarding the use of generic drugs in village x Bekasi City Dwi Imelda Afriliani; Anna Uswatun Hasanah Rochjana; Sylvi Adiana; Devi Maulina
Indonesian Journal of Health Science Vol 6 No 4 (2026)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v6i4.2403

Abstract

The use of generic drugs in the community remains suboptimal despite their equivalent efficacy to branded drugs and more affordable prices. One of the factors influencing this condition is the lack of public knowledge regarding generic drugs. This study aimed to determine the difference in the level of public knowledge before and after receiving education about the use of generic drugs in Village X, Bekasi City. This study employed a quantitative method with a pre-experimental one-group pretest-posttest design. The sample consisted of 73 respondents selected using a purposive sampling technique. Data were collected using a closed-ended questionnaire with a Guttman scale that had been tested for validity and reliability. Education was provided through counseling using leaflet media. Data were analyzed using univariate. analysis and the Wilcoxon Signed Rank Test with a significance level of α = 0.05. The results showed that before the educational intervention, 15 respondents (20.55%) had a good level of knowledge, 33 respondents (45.20%) had a moderate level, and 25 respondents (34.25%) had a poor level of knowledge. After the educational intervention, all 73 respondents (100%) had a good level of knowledge. The Wilcoxon Signed Rank Test showed a significance value of p = 0.000 (p < 0.05), indicating a significant difference in knowledge levels before and after the educational intervention. It can be concluded that there was a difference in the level of public knowledge regarding the use of generic drugs after the educational intervention. Continuous education is needed to improve public understanding and promote rational drug use.
Co-Authors Amalina Fakhriah Devi Maulina Dhega Rhefaldy Dermawan Dwi Imelda Afriliani Fani Aprilia Ilham Maulana Milda Rianty Lakoan Rif'aa Naflah Faadiyah Sakilah Alaisah Astuti Sylvi Adiana Varda Arianti