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All Journal Jurnal Biologi Tropis Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Kesehatan Tambusai AKSONA
Rosyidi, Rohadi Muhammad
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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LITERATUR REVIEW: CARING AND SUPPORTING MANAGEMENT FOR BRAIN TUMOR PATIENTS Mawaddah, Alfia Mawaddah; Buana, I Gede Aditya Satrya; Shinta, Ni Made Ayu; Arista, Rida Dwi; Rosyidi, Rohadi Muhammad
Jurnal Ilmu Kedokteran dan Kesehatan Vol 11, No 4 (2024): Volume 11 Nomor 4
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v11i4.13316

Abstract

Tumor merupakan penyakit yang dapat terjadi pada siapapun di semua usia dan dapat muncul di seluruh organ tubuh. Tumor otak menjadi salah satu penyakit yang dengan mortalitas tertinggi dan dapat memengaruhi kualitas hidup seseorang secara signifikan. Tingkat kejadian kasus tumor otak baru mencapai angka 6,4 per 100.000 orang per tahun dengan 33,4% tingkat kelangsungan hidup selama lima tahun secara keseluruhan. Pada laki – laki, tumor otak 1,58 kali lebih sering terjadi jika dibandingkan dengan perempuan. Kondisi ini membutuhkan perawatan dan dukungan yang tepat agar pasien dapat merasa nyaman dan terbantu dalam menghadapi segala tantangan yang dihadapai selama memiliki penyakitnya. Dalam beberapa tahun terakhir, manajemen perawatan dan dukungan memadai bagi pasien dengan tumor otak telah menjadi aspek yang semakin penting.
EVALUASI PENERIMAAN DAN PENYIMPANAN OBAT DI INSTALASI FARMASI RSUD KOTA MATARAM TAHUN 2024 Putri, Julia Ananda Eka; Saputra, Yoga Dwi; Rosyidi, Rohadi Muhammad; Hasina, Raisya
Jurnal Kesehatan Tambusai Vol. 6 No. 1 (2025): MARET 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i1.41939

Abstract

Obat adalah salah satu aspek penting yang harus tersedia di setiap fasilitas pelayanan kesehatan termasuk Rumah Sakit. Agar tercapai ketersediaan obat yang efisien, efektif dan rasional, obat harus dikelola dengan baik dan benar. Salah satu kegiatan pengelolaan obat di Rumah Sakit meliputi aspek penerimaan dan penyimpanan. Penelitian ini bertujuan untuk mengevaluasi Penerimaan dan Penyimpanan Obat di Instalasi Farmasi RSUD Kota Mataram Periode Tahun 2024. Penelitian ini merupakan penelitian deskriptif observasional dengan pendekatan Mix Metode. Pengumpulan data penerimaan diperoleh dari SP, faktur, kartu stok, pengamatan langsung diruang penyimpanan obat disertai dengan pengisian lembar penilaian dalam bentuk checklist dan validasi hasil kepada Kepala Instalasi Farmasi dan Kepala Gudang RSUD Kota Mataram. Hasil dianalisis menggunakan Microsoft excel, data hasil penelitian disajikan dalam bentuk persentase. Diperoleh persentase ketepatan aspek penerimaan obat 100% dan prosedur penyimpanan obat 96%. Berdasarkan hal tersebut dapat disimpulkan bahwa penerimaan dan penyimpanan obat di RSUD Kota Mataram telah sesuai dengan Petunjuk Standar Rumah Sakit Tahun 2019.
The Relathionship Between CD31 Immunohistochemical Expression and Meningioma Grading Differences Febriana, Nanggi Qoriatul; Rosyidi, Rohadi Muhammad; Januarman, Januarman; Rahim, Adelia Riezka; Prihatina, Lale Maulin
Jurnal Biologi Tropis Vol. 25 No. 1 (2025): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i1.8539

Abstract

The proper management of meningioma patients requires a definitive diagnosis of the meningioma grade by examining the expression of CD31 in tumor blood vessels using immunohistochemical staining. This study aims to determine the relationship between CD31 immunohistochemical expression and the grading differences of meningiomas. Nine paraffin block samples from the surgical tissue of meningioma patients were used, with three samples each from grade I, grade II, and grade III meningiomas. Immunohistochemical staining for CD31 was then performed on each meningioma slide, and the samples were observed under a binocular light microscope with 200x magnification. The results showed CD31 expression in grade I as 90%, 40%, and 80%; in grade II as 80%, 80%, and 60%; and in grade III as 40%, 20%, and negative (0%). The statistical test results of this study indicate a strong negative correlation between CD31 immunohistochemical expression and meningioma grading differences. The higher the meningioma grade, the lower the CD31 expression found, and vice versa. This research is important to assist neurosurgeons in the proper management of meningioma patients, potentially preventing poor prognosis and complications. It is hoped that future studies will analyze the relationship between CD31 immunohistochemical expression with subtypes of each meningioma grade and their respective locations.
Determinants of Executive Dysfunction: Serum NRF2 and Sociodemographic Profiles in Lombok Island’s Coastal Population Wulandari, Inayah; Nurhidayati, Nurhidayati; Hunaifi, Ilsa; Rivarti, Arina Windri; Harahap, Herpan Syafii; Saputri, Legis Octaviana; Suryani, Dini; Zubaidi, Fitriannisa Faradina; Rosyidi, Rohadi Muhammad
AKSONA Vol. 6 No. 1 (2026): JANUARY 2026
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/aksona.v6i1.74449

Abstract

Highlight: Coastal communities show high prevalence of cognitive decline. There is no correlation between NRF2 levels and executive function. Gender and education level were significantly associated with executive dysfunction.   ABSTRACT Introduction: Elderly people frequently suffer from neurodegenerative conditions that affect cognitive function. Redox homeostasis dysregulation plays a significant role in neurodegenerative diseases. Oxidative stress activates the transcription factor called nuclear factor erythroid 2-related factor 2 (NRF2), which is essential for regulating the expression of genes involved in cellular defense mechanisms. Objective: This study aimed to determine the relationship between serum NRF2 levels and executive function, as well as to identify other variables that may influence executive function among residents of coastal villages on Lombok Island. Methods: The study used a cross-sectional design with consecutive sampling. Data on sociodemographic characteristics, hypertension, diabetes mellitus, smoking status, and physical activity were collected. Statistical analyses employed Spearman's rank correlation test, Fisher's exact test, and logistic regression test. Results: A total of 39 participants were included, with an average age of 53.38 years. Most participants were female, had a low educational level, did not have hypertension or diabetes mellitus, had high physical activity levels, and were non-smokers. The average NRF2 level was 0.54 ng/mL. The correlation test showed no significant relationship between serum NRF2 levels and executive function. Fisher's exact test showed a significant relationship between gender and education with executive function. Furthermore, logistic regression analysis identified education level as a predictor of executive dysfunction. Conclusion: Serum NRF2 levels were not correlated with executive dysfunction. Educational level was identified as a predictive factor for executive dysfunction.
Co-Authors Arista, Rida Dwi Buana, I Gede Aditya Satrya Dini Suryani, Dini Febriana, Nanggi Qoriatul Hasina, Raisya Herpan Syafii Harahap Ilsa Hunaifi, Ilsa Januarman, Januarman Mawaddah, Alfia Mawaddah Nurhidayati Nurhidayati Prihatina, Lale Maulin Putri, Julia Ananda Eka Rahim, Adelia Riezka Rivarti, Arina Windri Saputra, Yoga Dwi Saputri, Legis Octaviana Shinta, Ni Made Ayu Wulandari, Inayah Zubaidi, Fitriannisa Faradina