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Formulasi Nutraseutikal Sediaan Gummy Candies Sari Buah Duwet (Syzygium cumini) Juliantoni, Yohanes; Wirasisya, Dyke Gita; Hasina, Raisya
Jurnal Kedokteran Vol 7 No 2 (2018)
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar Belakang: Senyawa radikal dapat merusak serabut kolagen kulit dan matrik dermis sehingga kulit menjadi kering, keriput, bahkan dapat terjadi penuaan dini. Upaya pencegahan yang dapat dilakukan yaitu dengan penggunaan bahan yang memiliki aktivitas antioksidan. Salah satu tanaman yang memiliki aktivitas antioksidan adalah buah duwet. Gummy candy merupakan permen kunyah semi basah yang terbuat dari gelatin dan karegenan. Penelitian ini bertujuan untuk mengetahui kapasitas antioksidan dan kualitas organoleptik pada gummy candy dari ekstrak sari buah duwet. Metode: Metode yang digunakan pada penelitian ini adalah melihat aktivitas penangkapan radikal DPPH dari buah duwet. Hasil: Hasil penelitian menunjukkan sampel ekstrak perasan buah duwet memiliki aktivitas penangkapan radikal bebas. Aktivitas penangkapan radikal DPPH sampel dilihat secara kualitatif dari perubahan warna. Ekstrak kemudian diformulasikan ke dalam bentuk gummy candy. Uji akseptabilitas menunjukkan formulasi nutraseutikal sediaan gummy candies sari buah duwet (Syzygium cumini) sudah baik namun harus dilakukan optimasi formula dan evaluasi sediaan untuk memperoleh hasil terbaik. Kesimpulan: Hasil uji tanggap rasa, aroma, dan kekenyalan sediaan gummy candies menunjukkan bahwa ekstrak buah duwet dapat dibuat menjadi sediaan gummy candies.
EVALUASI KETEPATAN PERENCANAAN DAN PENGADAAN CODEIN DI APOTEK X KOTA MATARAM PERIODE SEPTEMBER 2023 Dian Safitri, Afifa; Hasina, Raisya; Amira
Jurnal Kefarmasian Akfarindo Vol 9 No 2 (2024)
Publisher : Akademi Farmasi Indonesia Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37089/jofar.vi0.337

Abstract

Codein merupakan narkotik golongan III yang banyak diresepkan untuk pengobatan beberapa penyakit di Nusa Tenggara Barat seperti ISPA, batuk dan nyeri otot. Peningkatan pelayanan resep codein mengharuskan apotek untuk memperhatikan tahapan perencanaan dan pengadaan dengan tepat untuk menjamin ketersediaan codein sehingga dapat memberikan pemenuhan kebutuhan peresepan pasien. Evaluasi ketepatan perencanaan dan pengadaan berkaitan dengan efisiensi pengelolaan codein di apotek. Penelitian ini bertujuan untuk mengevaluasi ketepatan perencanaan dan pengadaan codein kekuatan sediaan 10 mg, 15 mg dan 20 mg pada periode September 2023 di Apotek X. Metode penelitian yang digunakan adalah observasional deskriptif dengan rancangan penelitian cross sectional. Pengumpulan data menggunakan metode retrospektif dengan teknik total sampling. Data primer berupa kartu stok codein periode September-Oktober 2023 dan resep codein periode September 2023 dan data sekunder berupa hasil wawancara informan apotek X. Analisis data menggunakan rumus persentase ketepatan perencanaan dan pengadaan pada tiap-tiap kekuatan sediaan codein berdasarkan standar efisiensi perencanaan dan pengadaan obat. Hasil penelitian ini diperoleh ketepatan tahap perencanaan codein 10 mg sebesar 2000% dan codein 20 mg 272,7%. Ketepatan tahap pengadaan codein 10 mg dan 20 mg masing-masing sebesar 100%. Adapun codein 15 mg tidak dilakukan perencanaan dan pengadaan karena jumlahnya di atas nilai buffer stock. Kesimpulan penelitian yaitu nilai ketepatan tahap perencanaan dan pengadaan codein di apotek X pada periode September 2023 tidak memenuhi standar ketepatan perencanaan dan pengadaan. Penyebab terjadinya ketidaktepatan pada tahap perencanaan dan pengadaan codein di apotek X ini karena kekosongan stok dari distributor, pola peresepan dan pola penyakit yang berubah-ubah.
EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN RAWAT INAP DENGAN METODE DDD (DEFINED DAILY DOSE)/ 100 PASIEN-HARI RAWAT DI RUMAH SAKIT UNIVERSITAS MATARAM TAHUN 2021 Putri, Enda Desideria; Hasina, Raisya; Andanalusia, Mahacita; Deccati, Rizqa Fersiyana; Dewi, Ni Made Amelia Ratnata
Jurnal Farmasi Higea Vol 16, No 2 (2024)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52689/higea.v16i2.601

Abstract

Adanya peningkatan prevalensi resistensi antibiotik di rumah sakit dapat disebabkan oleh penggunaan antibiotik yang kurang bijak dan berlebihan. Untuk mengatasi masalah ini, penting untuk menilai penggunaan antibiotik di rumah sakit. Penelitian ini bertujuan untuk mengevaluasi secara kuantitatif penggunaan antibiotik pada pasien rawat inap di Rumah Sakit Universitas Mataram. Penelitian ini menggunakan desain cross-sectional dengan pendekatan kuantitatif, dan pengumpulan data dilakukan secara retrospektif dengan memeriksa rekam medis tahun 2021. Populasi penelitian terdiri dari pasien rawat inap yang telah diberi resep antibiotik. Pemilihan pasien dilakukan dengan menggunakan teknik purposive sampling. Data penggunaan antibiotik diperoleh dari 121 rekam medis dan dianalisis secara deskriptif dengan metode ATC/DDD. Hasil penelitian menunjukkan bahwa ceftriaxone memiliki nilai kuantitas untuk dosis harian pasti (DDD) tertinggi sebesar 42,75 DDD/100 pasien-hari rawat, diikuti oleh cefixime sebesar 34,16 DDD/100 pasien-hari rawat, levofloxacin (IV) sebesar 20,93 DDD/100 pasien-hari rawat, dan azitromisin pada 15,05 DDD/100 pasien-hari rawat. Di antara seluruh antibiotik yang diperiksa pada penelitian ini, ceftriaxone memiliki nilai kuantitas DDD tertinggi per 100 hari pasien-hari rawat.
Pola penggunaan obat anti diabetes mellitus tipe-II pada pasien rawat inap di RSUD Praya tahun 2021 Novita, Adela; Hasina, Raisya; Harahap, Herpan Syafii
Sasambo Journal of Pharmacy Vol. 5 No. 1 (2024): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i1.254

Abstract

Diabetes mellitus is a metabolic disease characterized by hyperglycemia due to abnormalities in insulin secretion. The prevalence of people with diabetes mellitus in Indonesia reached 6.2% per year in 2020 and ranks 7th in the world with 8.5 million people. Based on the results of observations at the Praya Hospital in 2021, type-II diabetes mellitus is the 4th highest-order disease suffered by the community, especially Central Lombok Regency, with a total incidence of 131 patients. This study aims to determine the pattern of drug use and HbA1c profile in patients with type-II diabetes mellitus in the inpatient installation of Praya Hospital in 2021. This study was retrospective, using the Nonprobability Sampling method, namely the type of purposive sampling so that a sample of 96 medical records of diabetes mellitus patients was obtained type-II. The data is presented as pie charts and tables in percentages, which were analyzed using Microsoft Excel and SPSS version 25. From the results of this research, it was found that the pattern of drug use at Praya Hospital in 2021 was given the highest from each group namely the oral antidiabetic drug group (OAD) was in the Biguanid class with 61 drugs (8,13%), while insulin drugs were in the Rapid-Acting class with 343 drugs (45,73%), and the OAD + Insulin combination with 119 drugs (15,87%). For the HbA1c profile, high HbA1c levels were found in 76 patients (79%). This shows that blood glucose control is not reasonable. Based on the study's results, the recommended recommendation is that patients routinely control blood sugar and be educated on the accuracy of drug use to control blood sugar.
Pharmacist Goes to School: Promoting DAGUSIBU As A Pharmaceutical Education Tool for Adolescents Saputra, Yoga Dwi; Ulya, Tuhfatul; Hasina, Raisya; Aini, Siti Rahmatul; Puspitasari, Candra Eka; Andanalusia, Mahacita; Lisnasari, Baiq Risky Wahyu; Hamdin, Candra Dwipayana
Jurnal Gema Ngabdi Vol. 6 No. 3 (2024): JURNAL GEMA NGABDI
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jgn.v6i3.522

Abstract

Drug misuse is an urgent public health issue, often arising from a lack of knowledge about proper medication use. Research shows that over half of the medications worldwide are used irrationally. The DAGUSIBU program (Dapatkan, Gunakan, Simpan, Buang or known as Get, Use, Store, Dispose) was developed as a solution to address this issue by providing education on proper medication management. This community service activity was organized by the Pharmacy Study Program and the Pharmacy Professional Education Program (PSPPA), Faculty of Medicine and Health Sciences (FKIK), Universitas Mataram, on August 9, 2024, at Kesuma Catholic High School in Mataram. The primary goal of this activity was to teach students the correct ways to obtain, use, store, and dispose of medications, as well as to introduce the pharmacist profession and the Pharmacy program at UNRAM to high school students. The activity included interactive presentations on DAGUSIBU, an introduction to the pharmacist profession, and a quiz competition as an evaluation method. The quiz encouraged active student participation, with prizes to boost motivation. Despite challenges such as varying levels of student comprehension and time constraints, the activity successfully improved students’ understanding of rational drug use and introduced career opportunities in pharmacy. Overall, this activity proved effective in raising student awareness and knowledge, positively impacting their health literacy.
Anti –Inflammatory Activity of Propolis Trigona sp. Water Extract from North Lombok with Red Blood Cell Membrane Stability Method Humaira, Ani Fatin; Aini, Siti Rahmatul; Hasina, Raisya
Biology, Medicine, & Natural Product Chemistry Vol 13, No 2 (2024)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2024.132.555-558

Abstract

Propolis is a bee product that can be used as an anti-inflammatory. Cultivation of propolis-producing bees is also carried out in North Lombok. However, propolis has not been utilized optimally by the people of North Lombok. Apart from that, testing of North Lombok propolis is still limited to the chemical content and antioxidant activity of propolis extracted with ethanol solvent. Therefore, this study aims to determine the activity and effective concentration of North Lombok propolis water extract as an anti-inflammatory using the red blood cell membrane stability method. Groups include control groups such as positive control (diclofenac sodium), negative control (distilled water), and test groups (propolis water extract concentrations of 10%, 12.5%, 15%, 17.5%, 20%, 22.5%, 25%, 27.5%, and 30%). In The first step human blood was centrifuged of human blood, and then part of the red blood cells (sediment) was taken and saline was added to obtain a red blood cell suspension. Next, mixing the test solution was carried out in the order of 0.5 ml of red blood cell suspension, then 0.5 ml of extract was added (0.1% w/v Na-diclofenac solution in the positive control, distilled water in the negative control), 1 mL of buffer solution and 2 mL of hyposaline solution, then homogenized. Each group was incubated at 37°C for 30 minutes, then centrifuged for 10 minutes at 3000 rpm. The supernatant was taken, and the absorbance was read with a UV-Vis spectrophotometer at 560 nm. Next, the percentage value of red blood cell hemolysis protection was calculated. The data obtained were tested statistically using One-way ANOVA and post-hoc (LSD) tests SPSS version 29. The results showed that propolis water extract concentrations were 10%, 12.5%, 15%, 17.5%, 20%, 22.5%, 25%, 27.5%, and 30% have anti-inflammatory activity because they can increase the stability of the red blood cell membrane with a percentage of hemolysis protection of respectively 57.92%, 59.99%, 60.99%, 61.99%, 64.31%, 69.59%, 75.07%, 79.77% and 84.45%. Propolis water extract concentrations of 10%, 12.5%, 15%, 17.5%, 20%, 22.5%, and 25% had anti-inflammatory effects that were not significantly different from the positive control (p>0.05). The 27.5 % and 30% concentrations had a higher percent hemolysis protection value than the positive control (p<0.05).
EVALUASI PENERIMAAN DAN PENYIMPANAN OBAT DI INSTALASI FARMASI RSUD KOTA MATARAM TAHUN 2024 Putri, Julia Ananda Eka; Saputra, Yoga Dwi; Rosyidi, Rohadi Muhammad; Hasina, Raisya
Jurnal Kesehatan Tambusai Vol. 6 No. 1 (2025): MARET 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i1.41939

Abstract

Obat adalah salah satu aspek penting yang harus tersedia di setiap fasilitas pelayanan kesehatan termasuk Rumah Sakit. Agar tercapai ketersediaan obat yang efisien, efektif dan rasional, obat harus dikelola dengan baik dan benar. Salah satu kegiatan pengelolaan obat di Rumah Sakit meliputi aspek penerimaan dan penyimpanan. Penelitian ini bertujuan untuk mengevaluasi Penerimaan dan Penyimpanan Obat di Instalasi Farmasi RSUD Kota Mataram Periode Tahun 2024. Penelitian ini merupakan penelitian deskriptif observasional dengan pendekatan Mix Metode. Pengumpulan data penerimaan diperoleh dari SP, faktur, kartu stok, pengamatan langsung diruang penyimpanan obat disertai dengan pengisian lembar penilaian dalam bentuk checklist dan validasi hasil kepada Kepala Instalasi Farmasi dan Kepala Gudang RSUD Kota Mataram. Hasil dianalisis menggunakan Microsoft excel, data hasil penelitian disajikan dalam bentuk persentase. Diperoleh persentase ketepatan aspek penerimaan obat 100% dan prosedur penyimpanan obat 96%. Berdasarkan hal tersebut dapat disimpulkan bahwa penerimaan dan penyimpanan obat di RSUD Kota Mataram telah sesuai dengan Petunjuk Standar Rumah Sakit Tahun 2019.
EDUKASI PENCEGAHAN DAN PENANGANAN DIARE BAGI ANAK DI PANTI ASUHAN AL-IKHLAS AMPENAN Ulya, Tuhfatul; Budastra, Wayan Cintya Ganes; Hasina, Raisya; Safitri, Afifa Dian
Jurnal Abdi Insani Vol 12 No 6 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i6.2591

Abstract

Diarrhea is a common illness among children and remains a leading cause of death in children under five globally, including in Indonesia. The high incidence of diarrhea in children is often due to a lack of knowledge about its prevention and treatment. This activity aimed to increase the awareness of children at Al-Ikhlas Orphanage, Ampenan regarding the recognition, prevention, management, and dangers of diarrhea through a health promotion program. The method included a pre-test, interactive health education using posters, and a post-test. A total of 39 children participated in the activity. The average pre-test score was 63.5, which decreased to 61 in the post-test. This decline may be due to unfamiliar medical terms used during the session. However, the activity succeeded in raising basic awareness among the children about maintaining hygiene to prevent diarrhea. Simple and interactive health education should be further developed to improve children's understanding in orphanage environments.
EDUKASI DAN DEMONSTRASI PEMANFAATAN TANAMAN KATANG-KATANG (IPOMOEA PES- CAPRAE) DALAM PENGOBATAN TRADISIONAL DI DUSUN MUARA PUTAT, DESA PEMENANG TIMUR, LOMBOK UTARA Hasina, Raisya; Aini, Siti Rahmatul; Hamdin, Candra Dwipayana; Ulya, Tuhfatul; Ananta, Muhammad Naufal Farras; Alamanda, Baiq Irzana Putri; Putri, Dheden Nurhani Bija; Yazid Maula
Jurnal Abdi Insani Vol 12 No 7 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i7.2704

Abstract

Ipomoea pes-caprae (katang-katang) adalah tanaman liar pesisir yang tersebar luas di wilayah tropis dan subtropis serta mampu beradaptasi di lingkungan berkadar garam tinggi. Perannya penting dalam ekosistem pantai, seperti mencegah erosi dan mendukung restorasi vegetasi. Daunnya umum digunakan secara tradisional untuk pengobatan gangguan pencernaan dan penyakit kulit. Di Dusun Muara Putat, Lombok Utara, tanaman ini belum dimanfaatkan secara optimal meski potensinya besar secara ekologis, terapeutik, dan ekonomis. Kegiatan ini bertujuan untuk meningkatkan wawasan dan keterampilan warga Dusun Muara Putat, Kabupaten Lombok Utara, dalam memanfaatkan katang-katang sebagai alternatif pengobatan tradisional. Pendekatan yang digunakan mencakup penyuluhan berupa sosialisasi dan praktik langsung. Kegiatan ini menggabungkan pendekatan sosialisasi dan praktik langsung, diawali dengan pre-test untuk mengukur pengetahuan awal peserta. Materi mencakup identifikasi morfologi tanaman katang-katang, kandungan bioaktif, manfaat farmakologis, dan teknik pengolahan sederhana. Peserta dilatih secara langsung, lalu dievaluasi melalui post-test untuk mengukur peningkatan pemahaman. Hasil menunjukkan peningkatan pengetahuan peserta, dengan rata-rata nilai pre-test sebesar 60 yang meningkat menjadi 80 pada post-test. Selain itu, peserta juga menunjukkan kemampuan praktik dalam mengolah tanaman untuk pengobatan rumah tangga. Penyuluhan melalui metode sosialisasi dan demonstrasi langsung dengan pendekatan partisipatif ini terbukti efektif dalam meningkatkan pengetahuan masyarakat Dusun Muara Putat tentang pengobatan tradisional, khususnya dalam pemanfaatan tanaman katang-katang (Ipomoea pes-caprae). Kesimpulannya, penyuluhan partisipatif di Dusun Muara Putat efektif meningkatkan pemahaman dan keterampilan masyarakat dalam pemanfaatan katang-katang sebagai obat tradisional.  
Pattern of Type-II Anti-Diabetes Mellitus Drug Use in Inpatients in Regional General Hospital of NTB Province in 2023 Adinda, Putri; Hasina, Raisya; Aini, Siti Rahmatul
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10114

Abstract

Diabetes Mellitus is a disease with the fifth highest mortality rate in the world because it can cause serious complications such as neuropathy, nephropathy, and retinopathy. This study aims to determine the pattern of use of antidiabetic type 2 drugs in hospitalized patients at the NTB Provincial Hospital in 2023. This study was retrospective using the Probability Sampling method, namely the Simple Random Sampling type, so that a sample of 90 medical records of patients with type 2 diabetes mellitus was obtained. The data were analyzed using chi-square test using Microsoft Excel and SPSS version 25. The results of the study showed that the use of insulin antidiabetic drugs with a fast-acting insulin class was the most prescribed antidiabetic drug with a total of 603 (42.33%), while oral antidiabetic drugs with a biguanide class, namely metformin, were the most widely used oral antidiabetic drugs with a total of 246 (52.45%). Gender, age, and BMI did not significantly correlate with patient blood sugar management, according to the Chi-Square test analysis (p value > 0.05). However, the blood sugar control treatment time revealed a p value < 0.05, indicating a substantial correlation between the two variables. The study concludes that, according to the pattern of type 2 antidiabetic medication usage among hospitalized patients at the NTB Provincial Hospital in 2023, the most commonly used medications in the NTB Provincial General Hospital during that year were 603 (42.33%) insulin class antidiabetic medications, specifically rapid-acting insulin.