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Formulasi Gel Sabun Wajah Ekstrak Etanol Daun Putihan (Chromolaena odorata L.) Sebagai Antijerawat Monica Suryani; Manahan Situmorang; Steven Tandiono
Jurnal Ilmu Kesehatan dan Gizi Vol. 1 No. 1 (2023): Januari: Jurnal Ilmu Kesehatan dan Gizi
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (577.42 KB) | DOI: 10.55606/jikg.v1i1.959

Abstract

Acne is a skin disease due to chronic inflammation with complex pathogenesis. The public has empirically used the white plant to treat wounds on the skin, it contains flavonoids, saponins, and tannins which can protect the skin from bacteria and can inhibit bacterial growth. This study aims to test the antibacterial activity against Propionibacterium acnes. The ethanol extract of Putihan leaves was obtained by maceration using 96% ethanol solvent, formulated and evaluated for facial soap gel preparations of ethanol extract of Putihan leaves with various extract concentrations of 0% (F0), 10% (F1), 13% (F2), and 15% (F3) which testing antibacterial activity against Propionibacterium acnes. The results showed that the antibacterial activity of the facial soap gel preparation of ethanol extract of Putihan leaves with a concentration of 10% had an inhibition of 8.4 ± 0.20 mm, 13% had an inhibition of 9.5 ± 0.23 mm and 15% had an inhibition of 10.6 ± 0.64mm. Based on this description, the resulting gel preparation has antibacterial activity against Propionibacterium acne. The three formulas are included in the medium inhibition zone category, but the one with the broadest inhibition zone is at a concentration of 15%.
Sosialisasi Dan Edukasi Tentang Diabetes Mellitus Dagusibu Dalam Meningkatkan Rasionalitas Penggunaan Obat Monica Suryani; Manahan Situmorang; Steven Tandiono
Jurnal Pengabdian Masyarakat Indonesia Sejahtera Vol. 2 No. 1 (2023): Maret : Jurnal Pengabdian Masyarakat Indonesia Sejahtera
Publisher : STAI YPIQ BAUBAU, SULAWESI TENGGARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59059/jpmis.v2i1.95

Abstract

Diabetes Mellitus (DM) merupakan masalah kesehatan global yang insidensinya semakin meningkat. Indonesia menempati peringkat 4 di dunia setelah Amerika Serikat India dan China. Peningkatan kemakmuran di negara berkembang dan perubahan gaya hidup menyebabkan peningkatan prevalensi penyakit degeneratif salah satunya Diabetes Mellitus (DM). Tujuan kegiatan pengabdian ini adalah untuk memberikan sosialisasi dan edukasi tentang diabetes mellitus dagusibu dalam meningkatkan rasionalitas penggunaan obat kepada masyarakat. Metode kegiatan ini melibatkan apoteker dan masyarakat di Taman Cadika, Kota Medan, Sumatera Utara. Hasil dari kegiatan ini adalah Tim pengabdian masyarakat berharap agar masyarakat dapat mendapatkan pengetahuan tentang diabetes mellitus dagusibu dalam meningkatkan rasionalitas penggunaan obat serta cara mendapatkan, gunakan, menyimpan, dan membuang obat antibiotik yang benar, sehingga tidak terjadi penyalahgunaan obat. Berdasarkan hasil kegiatan Pengabdian kepada Masyarakat yang dilakukan oleh Apoteker Kota Medan. Kegiatan ini berjalan dengan baik serta masyarakat dapat menerima pengetahuan tentang sosialisasi dan edukasi tentang diabetes mellitus dagusibu dalam meningkatkan rasionalitas penggunaan obat.
Pemberian Edukasi Kepada Masyarakat Pemanfaatan Kulit Buah Pir Menjadi Sediaan Sheet Mask yang berkhasiat sebagai Antioksidan Monica Suryani; Manahan Situmorang; Steven Tandiono; Cut Masyitah Thaib
Compromise Journal Community Proffesional Service Journal Vol. 2 No. 3 (2024): Compromise Journal: Community Professional Service Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/compromisejournal.v2i3.333

Abstract

Pear skin contains flavonoids which have potential as antioxidants. Considering the existence of humans as social creatures, who in interacting with each other require self-confidence in order to be well received. Masks are a type of cosmetic treatment that is well known and widely used. The mask works deeply to remove dead horn cells on the skin. The aim of this community service is to provide education to the public about the benefits of pear skin as an antioxidant. This method of community service is by providing education to the public by presenting material about pear peels which are used as antioxidants and introducing natural ways to use pear peels. The results of the activities of implementing the community service program are in the form of educating the public about the benefits of pear skin, namely as an antioxidant. Conclusion: Community service in managing pear skin as an antioxidant meets quantity and quality.
Formulasi dan Evaluasi Sediaan Sheet Mask dari Ekstrak Etanol Kulit Buah Pir (Pyrus Bretschneideri) Sebagai Antioksidan dengan Metode DPPH Monica Suryani; Manahan Situmorang; Steven Tandiono; Supartiningsih Supartiningsih
Vitalitas Medis : Jurnal Kesehatan dan Kedokteran Vol. 1 No. 3 (2024): Juli : Vitalitas Medis : Jurnal Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/vimed.v1i3.674

Abstract

Pear skin contains flavonoids which have potential as antioxidants. Considering the existence of humans as social creatures, interacting with each other requires self-confidence to be well accepted. For this reason, humans need self-care to appear charming, attractive and full of self-confidence. Masks are a type of cosmetic treatment that is well known and widely used. The mask works deeply to remove dead horn cells on the skin. This research aimed to determine the potential antioxidant activity of the ethanol extract of pear peel (Pyrus bretschneideri) which was formulated as a sheet mask preparation. Extraction was carried out by maceration using 96% ethanol to obtain pear peel extract. The antioxidant activity test method was carried out using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The results obtained from the concentration of the sheet mask preparation of pear peel extract (Phyrus bretschneideri) were homogeneous and stable. The pH results obtained from F0 (5,1), F1 (5,4), F2 (5,5), F3 (5,6), are still within the safe range of facial skin pH. The results of the antioxidant activity test showed that the IC50 value for F1 was 84.58 ppm with intensity (Strong), F2 69.96 ppm with intensity (Strong), and F3 63.79 ppm with intensity (Strong).
Formulasi dan Uji Penetrasi In Vitro Sediaan Gel Sistem FitosomEkstrak Buah Asam Jawa (Tamarindus indica L.) Devina Chandra; Cut Masyithah Thaib; Steven Tandiono; Manuppak Irianto Tampubolon
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i4.559

Abstract

Tamarind fruit extract (Tamarindus indica L.) contained flavonoids such as quercetin as antioxidants. The hydrophilic nature of tamarind fruit (Tamarindus indica L.) led to poor penetration and low bioavailability. Research was conducted to address penetration issues by preparing a phytosome drug delivery system incorporated into tamarind fruit extract formulations. The study aimed to formulate a tamarind fruit extract gel with phytosome preparation to enhance the effectiveness of active ingredient penetration. Phytosome preparation was carried out using the thin layer hydration method with concentrations of 1.5%, 3%, and 4.5%. Evaluation of the gel preparations showed that the color of FI (1.5%) was yellowish-brown, F2 (3%) was light brown, and F3 (4.5%) was dark brown. All formulations had a distinctive odor, pH ranged from 4.3 to 5.2, viscosity ranged from 4,333 to 7,500 cPs, spreadability ranged from 5.2 to 5.8 cm, and they had good stability, were homogeneous, and did not cause irritation. Penetration tests using Franz diffusion cells were performed on male rabbit skin (Oryctolagus cuniculus). The penetration results were analyzed using UV-Vis spectrophotometry with a maximum wavelength of 435 nm. The cumulative amount penetrated was 13.2085 ppm for F1 (1.5%), 14.2142 ppm for F2 (3%), and 15.5136 ppm for F3 (4.5%). In contrast, the tamarind fruit extract gel without phytosomes had a cumulative penetration amount of 1.3684 ppm. The tamarind fruit extract's phytosome gel showed better penetration than the tamarind fruit extract gel without phytosomes.
Penyuluhan kepada Masyarakat tentang Sediaan Farmasi Berbasis Bahan Alam di Sekolah Tanjung Pura Langkat Natanael Priltius; Devina Chandra; Steven Tandiono; Manuppak Irianto Tampubolon
Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia Vol. 2 No. 2 (2023): Juni : Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia
Publisher : Sekolah Tinggi Ilmu Administrasi Yappi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jppmi.v2i2.570

Abstract

Herbal plant-based pharmaceutical preparations are currently being developed because currently many industries produce and distribute pharmaceutical preparations containing natural ingredients that make it easier for the public to use. The purpose of this extension activity is to provide knowledge to the public about natural-based pharmaceutical preparations at schools in Tanjung Pura, Langkat. The method used in this activity involves lecturers by providing leaflets and materials to the public. The results of the implementation of this activity to the public are in the form of information and education about natural-based pharmaceutical preparations. The result of this activity is that the community service team hopes that the public will receive information about natural-based pharmaceutical preparations
Pemberdayaan Buah Asam Jawa (Tamarindus Indica L.) Menjadi Sediaan Gel Sistem Fitosom sebagai Antioksidan Devina Chandra; Cut Masyithah Thaib; Steven Tandiono; Manuppak Irianto Tampubolon
Compromise Journal Community Proffesional Service Journal Vol. 3 No. 1 (2025): Compromise Journal : Community Proffesional Service Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/compromisejournal.v3i1.561

Abstract

Empowering the community using one of the cooking spices to become something which has high selling power because of its effectiveness will increase people's enthusiasm for using it. Tamarind fruit has bioactive compounds which often used as natural antioxidants and will be made into phytosome system gel preparations which can improve better penetration of drugs into the skin. The aim of this service was that the community is expected to provide education about tamarind fruit in Klambir V Village, Medan, Indonesia. This community service method was carried out using leaflets, modules, power points and presentations to the community. The result of this service was an increase in public knowledge of tamarind fruit as an antioxidant by 87%.