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Manahan Situmorang
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Religion Agriculture, Biological Sciences & Forestry Humanities Chemistry Computer Science & IT Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Formulasi Gel Sabun Wajah Ekstrak Etanol Daun Putihan (Chromolaena odorata L.) Sebagai Antijerawat Monica Suryani; Manahan Situmorang; Steven Tandiono
Jurnal Ilmu Kesehatan dan Gizi Vol. 1 No. 1 (2023): Januari: Jurnal Ilmu Kesehatan dan Gizi
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (577.42 KB) | DOI: 10.55606/jikg.v1i1.959

Abstract

Acne is a skin disease due to chronic inflammation with complex pathogenesis. The public has empirically used the white plant to treat wounds on the skin, it contains flavonoids, saponins, and tannins which can protect the skin from bacteria and can inhibit bacterial growth. This study aims to test the antibacterial activity against Propionibacterium acnes. The ethanol extract of Putihan leaves was obtained by maceration using 96% ethanol solvent, formulated and evaluated for facial soap gel preparations of ethanol extract of Putihan leaves with various extract concentrations of 0% (F0), 10% (F1), 13% (F2), and 15% (F3) which testing antibacterial activity against Propionibacterium acnes. The results showed that the antibacterial activity of the facial soap gel preparation of ethanol extract of Putihan leaves with a concentration of 10% had an inhibition of 8.4 ± 0.20 mm, 13% had an inhibition of 9.5 ± 0.23 mm and 15% had an inhibition of 10.6 ± 0.64mm. Based on this description, the resulting gel preparation has antibacterial activity against Propionibacterium acne. The three formulas are included in the medium inhibition zone category, but the one with the broadest inhibition zone is at a concentration of 15%.
Evaluasi Kombinasi Infusa Daun Sirih (Piper betle L.) dan Infusa Rimpang Jahe (Zingiber officinale-Roscoe) terhadap Tikus Jantan (Rattus norvegicus) Galur Wistar Sebagai Model Hiperglikemia Dhea Nur Fadhilah; Manahan Situmorang; Dumartina Hutahuruk; Julia Susanti
Jurnal Ilmu Kesehatan dan Gizi Vol. 1 No. 3 (2023): Juli: Jurnal Imu Kesehatan dan Gizi
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikg.v1i3.1731

Abstract

Hyperglycemia occurs when the body's condition is too much blood glucose that exceeds normal limits in the body because the body does not produce insulin properly. Betel leaves and ginger rhizomes have long been used by the people in Indonesia as traditional medicines that are believed to reduce blood glucose levels. This study aims to determine the effectiveness of betel leaves and ginger rhizomes empirically to reduce blood glucose levels in hyperglycemia male rats. Betel leaves and rhizomes of ginger are made in the form of infusions and used on 30 heads of hyperglycemia mice divided into 6 groups. Normal group, negative group induced alloxane, positive group (glibenklamide), betel leaf infusion group, ginger rhizome infusion group, betel leaf infusion combination group and ginger rhizome infusion, testing was carried out for 30 days. Data were analyzed with IBM SPSS 20.0 ANOVA and post hoc tukey HSD assays. The results showed that betel leaf infusion at a dose of 2 ml / kg BB and ginger rhizome infusion dose of 2ml / kg BB single administration could reduce blood glucose levels while in combination administration it was seen that there was less effective in reducing blood glucose levels in male white rats.
BAKTI SOSIAL HISFARMA DAN PERSIT KCK HUBDAM I/BBU HIMPUNAN SEMINAT FARMASI MASYARAKAT PD IAI SUMATRA UTARA Manahan Situmorang; Dumartina Hutahuruk; Jon Kenedy Marpaung; Siti Nurbaya; Natanael Priltius
Nusantara: Jurnal Pengabdian kepada Masyarakat Vol. 2 No. 2 (2022): Mei: Jurnal Pengabdian kepada Masyarakat
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (157.49 KB) | DOI: 10.55606/nusantara.v2i2.223

Abstract

Blood donation activity is the obligation of every community as a form of concern for others. Many people do not know about the health benefits of blood donation. There are even people who are reluctant to donate blood because they are worried about the side effects it causes. In fact, by donating blood, the blood cells in the body are replaced more quickly with new ones. The purpose of this activity was to carry out the HISFARMA Social Service and Persit KCK HUBDAM I/BBU Community Pharmacy Seminate Association PD IAI North Sumatra. This activity was carried out by conducting a site survey with the implementation team, meeting with Representatives of PERSIT KCK HUBDAM I/BBU, Medan, North Sumatra. This activity was opened by the presenter, after that singing the Indonesia Raya anthem, welcoming remarks, followed by blood donation activities, blood sugar checks, a careful echo talk show and ended with a group photo. Implementation of community service in the form of social services in educating the public on the importance of blood donation, blood sugar checks and careful echo talk shows. Health Checkup has many benefits. When donating blood, the blood cells in the body are replaced more quickly with new ones. If you donate blood once every three months, your body will stay healthy. Besides being useful for helping others, blood donation also makes our bodies healthier. So it can be concluded that this activity has a good impact and influence on people's knowledge in carrying out this activity.
Sosialisasi Dan Edukasi Tentang Diabetes Mellitus Dagusibu Dalam Meningkatkan Rasionalitas Penggunaan Obat Monica Suryani; Manahan Situmorang; Steven Tandiono
Jurnal Pengabdian Masyarakat Indonesia Sejahtera Vol. 2 No. 1 (2023): Maret : Jurnal Pengabdian Masyarakat Indonesia Sejahtera
Publisher : STAI YPIQ BAUBAU, SULAWESI TENGGARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59059/jpmis.v2i1.95

Abstract

Diabetes Mellitus (DM) merupakan masalah kesehatan global yang insidensinya semakin meningkat. Indonesia menempati peringkat 4 di dunia setelah Amerika Serikat India dan China. Peningkatan kemakmuran di negara berkembang dan perubahan gaya hidup menyebabkan peningkatan prevalensi penyakit degeneratif salah satunya Diabetes Mellitus (DM). Tujuan kegiatan pengabdian ini adalah untuk memberikan sosialisasi dan edukasi tentang diabetes mellitus dagusibu dalam meningkatkan rasionalitas penggunaan obat kepada masyarakat. Metode kegiatan ini melibatkan apoteker dan masyarakat di Taman Cadika, Kota Medan, Sumatera Utara. Hasil dari kegiatan ini adalah Tim pengabdian masyarakat berharap agar masyarakat dapat mendapatkan pengetahuan tentang diabetes mellitus dagusibu dalam meningkatkan rasionalitas penggunaan obat serta cara mendapatkan, gunakan, menyimpan, dan membuang obat antibiotik yang benar, sehingga tidak terjadi penyalahgunaan obat. Berdasarkan hasil kegiatan Pengabdian kepada Masyarakat yang dilakukan oleh Apoteker Kota Medan. Kegiatan ini berjalan dengan baik serta masyarakat dapat menerima pengetahuan tentang sosialisasi dan edukasi tentang diabetes mellitus dagusibu dalam meningkatkan rasionalitas penggunaan obat.
Formulasi dan Evaluasi Sediaan Sheet Mask dari Ekstrak Etanol Kulit Buah Pir (Pyrus Bretschneideri) Sebagai Antioksidan dengan Metode DPPH Monica Suryani; Manahan Situmorang; Steven Tandiono; Supartiningsih Supartiningsih
Vitalitas Medis : Jurnal Kesehatan dan Kedokteran Vol. 1 No. 3 (2024): Juli : Vitalitas Medis : Jurnal Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/vimed.v1i3.674

Abstract

Pear skin contains flavonoids which have potential as antioxidants. Considering the existence of humans as social creatures, interacting with each other requires self-confidence to be well accepted. For this reason, humans need self-care to appear charming, attractive and full of self-confidence. Masks are a type of cosmetic treatment that is well known and widely used. The mask works deeply to remove dead horn cells on the skin. This research aimed to determine the potential antioxidant activity of the ethanol extract of pear peel (Pyrus bretschneideri) which was formulated as a sheet mask preparation. Extraction was carried out by maceration using 96% ethanol to obtain pear peel extract. The antioxidant activity test method was carried out using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The results obtained from the concentration of the sheet mask preparation of pear peel extract (Phyrus bretschneideri) were homogeneous and stable. The pH results obtained from F0 (5,1), F1 (5,4), F2 (5,5), F3 (5,6), are still within the safe range of facial skin pH. The results of the antioxidant activity test showed that the IC50 value for F1 was 84.58 ppm with intensity (Strong), F2 69.96 ppm with intensity (Strong), and F3 63.79 ppm with intensity (Strong).
Pemberdayaan Masyarakat dalam Pembuatan Emulgel Herbal dari Ekstrak Daun Leunca (Solanum Nigrum) sebagai Alternatif Antibakteri Kulit Jon Kenedy Marpaung; Manahan Situmorang; Yanti Musyawarah; Natanael Priltius
jurnal ABDIMAS Indonesia Vol. 2 No. 4 (2024): Desember: Jurnal ABDIMAS Indonesia
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jurai.v2i4.2363

Abstract

Leunca leaves are rich in bioactive compounds such as tannins, alkaloids, flavonoids, phenols and steroids, making it possible to use them as an antibacterial. This community service aims to empower the community by introducing and involving them in the production of herbal emulgel from Leunca leaf extract (Solanum nigrum), which had potential as a natural antibacterial agent, particularly for skin care. Leunca leaves, rich in bioactive compounds such as alkaloids and flavonoids, had antibacterial properties that can effectively treat skin infections. Through counseling and practical training, the community is taught how to process Leunca leaves into an emulgel formulation that is easy to use and has health benefits. The method of this community service was carried out through presentations, distribution of modules, and demonstrations of emulgel production to the community. Evaluation results showed an increase in community knowledge about the benefits of Leunca leaves as a natural antibacterial agent, with knowledge improving from 15% to 80% after the counseling. It is hoped that this initiative will raise awareness and promote the use of local herbal ingredients in skin care, as well as open up opportunities for herbal-based entrepreneurship that can improve the community's well-being
Edukasi Pengenalan Minuman Herbal, Sebagai Minuman Kesehatan pada Masyarakat di Sekitaran Apotek Sari Mutiara Manahan Situmorang; Devina Chandra; Dumartina Hutauruk; Theesyah R. Sianturi; Nurlaili Safitri; Widia Sari; Eva Diansari Marbun
Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat. Vol. 3 No. 3 (2025): August : Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/natural.v3i3.1656

Abstract

Traditional herbal drinks based on natural ingredients such as ginger, lemongrass, and lemon are widely known to have various health benefits. However, not all levels of society understand the properties, processing methods, and proper consumption of these herbal drinks. This community service activity aims to provide education regarding the benefits of herbal drinks to the community around the Sari Mutiara Pharmacy. The implementation method used was an interactive lecture, question and answer session, and distribution of information brochures. The results of the activity showed an increase in public understanding of the benefits and uses of herbal drinks. This activity was attended by 20 residents and is expected to be the first step in increasing awareness of consuming herbal drinks as a health promotion and prevention effort. Conclusion: Thecommunityserviceactivityto introduceherbaldrinks to the community around the Sari Mutiara Pharmacy successfully increased public understanding and interest in consuming herbal drinks as part of a healthy lifestyle.
REVIEW ARTIKEL: ANALISIS AKTIVITAS ANTIOKSIDAN GENUS Syzygium MENGGUNAKAN METODE DPPH Manahan Situmorang; Devina Chandra; Dumartina Hutauruk; Widia Sari; Aufa Azkia; Theesyah R Sianturi; Eva Diansari Marbun
Jurnal Intelek Dan Cendikiawan Nusantara Vol. 2 No. 3 (2025): JUNI-JULI 2025
Publisher : PT. Intelek Cendikiawan Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Genus Syzygium telah banyak diteliti karena potensinya dalam menetralkan radikal bebas yang diketahui berperan dalam perkembangan penyakit degeneratif. Penelitian ini bertujuan untuk meninjau dan membandingkan aktivitas antioksidan dari berbagai spesies Syzygium dengan metode DPPH (2,2-diphenyl-1-picrylhydrazyl). Kajian dilakukan dengan cara pendekatan deskriptif melalui telaah literatur terhadap sepuluh artikel ilmiah. Berdasarkan hasil kajian, ekstrak daun Syzygium zollingerianum menunjukkan potensi antioksidan tertinggi dengan nilai IC₅₀ sebesar 0,57 μg/mL, melampaui efektivitas vitamin C sebagai pembanding. Aktivitas tinggi juga ditunjukkan oleh ekstrak biji S. polycephalum (IC₅₀ = 5,246 ppm) dan kulit batang S. guineense (IC₅₀ = 5,62 ppm). Beberapa studi menunjukkan bahwa daun S. polyanthum memiliki aktivitas sangat kuat dengan nilai IC₅₀ antara 13–15 ppm. Aktivitas kuat juga ditemukan pada buah Lobi-lobi (IC₅₀ = 50,01 ppm) dan daging buah kupa (IC₅₀ = 58,08 ppm). Sementara itu, aktivitas sedang hingga lemah ditemukan pada daun pucuk merah (IC₅₀ = 337 ppm), daun jamblang (IC₅₀ = 162,2 ppm), dan kulit batang jamblang (IC₅₀ = 164,3 ppm), sedangkan fraksi n-heksan menunjukkan aktivitas sangat lemah (IC₅₀ = 5235,6 ppm). Variasi aktivitas ini dipengaruhi oleh bagian tanaman, jenis pelarut, dan kandungan senyawa bioaktif seperti fenolik dan flavonoid. Kesimpulannya, spesies seperti S. zollingerianum, S. polycephalum, dan S. guineense memiliki potensi tertinggi, dengan bagian daun, biji, dan kulit batang sebagai sumber antioksidan paling efektif untuk aplikasi kesehatan preventif.
Edukasi Pemanfaatan Daun Kapulaga terhadap Tambak Udang di Desa Sikhorilafau Dumartina Hutauruk; Manahan Situmorang; Suharyanisa Suharyanisa; Yanti Musyawarah
Jurnal Nusantara Berbakti Vol. 3 No. 2 (2025): April: Jurnal Nusantara Berbakti
Publisher : Universitas Kristen Indonesia Toraja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/jnb.v3i2.641

Abstract

The many negative effects on the use of chemical-based medicine have made researchers increasingly interested in looking for alternative natural ingredients that have high therapeutic potential and minimal side effects. One of the plants that is often used as a medicinal ingredient is cardamom (Amomum cardamomum L.), which comes from the Zingiberaceae family. Cardamom has been widely used by the community as an aromatic, carmimental (reducing gas in the stomach), cough medicine, mouth freshener, and various other traditional medicines. The content of bioactive compounds such as alkaloids, flavonoids, tannins, and saponins in cardamom is believed to play an important role in providing pharmacological effects. This study aims to analyze the bioactivity level of toxicity of cardamom leaf ethanol extract against shrimp larvae Artemia salina L. using the Brine Shrimp Lethality Test (BSLT) method and determine the LC₅₀ value as a toxicity parameter. The research method used an experimental quantitative approach with six treatment concentrations, namely 25 ppm, 50 ppm, 100 ppm, 200 ppm, 500 ppm, and 1000 ppm, as well as one negative control. Each treatment was replicated five times to get accurate results. A total of 350 Artemia salina larvae were used, with 10 larvae for each concentration test. Larval mortality was calculated after 24 hours of treatment to determine the potential toxicity of the extract. In addition to laboratory research, community service programs are carried out to increase coastal communities' understanding of the use of cardamom leaves for pond shrimp larvae. This education is important because the results of the research are expected to be the basis for the use of natural materials that are safer, more environmentally friendly, and sustainable in the management of shrimp ponds.
TINJAUAN LITERATUR: KAJIAN EFEKTIVITAS ANTI JAMUR DAUN SIRIH HIJAU & KUNYIT DALAM PENGOBATAN KEPUTIHAN WANITA Natanael Priltius; Candrika Kumala; Manahan Situmorang; Nova Indah Bakara; Sri Indriyani Sinaga; Febrina Theresa Manurung
Berajah Journal Vol. 5 No. 12 (2026): Berajah Journal
Publisher : CV. Lafadz Jaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/bj.v5i12.155

Abstract

Pathological vaginal discharge is a common reproductive health problem among women, especially in Indonesia, with a prevalence reaching 75%. Conventional treatment for vaginal discharge is often constrained by cost and limited access to healthcare services, making traditional remedies such as green betel leaf decoction and turmeric extract popular alternatives. This study aimed to examine the antifungal effectiveness of green betel leaf decoction and turmeric in significantly reducing pathological vaginal discharge among adolescent to adult women over the long term. The research method employed was a literature review with a systematic search of the Google Scholar database from January 2020 to July 2024 using the keyword “Traditional Medicine for Vaginal Discharge.” From 3,010 initial articles, after screening for duplication and relevance, five articles were selected for descriptive analysis. The results showed that green betel leaf decoction and turmeric extract had high effectiveness in reducing pathological vaginal discharge, as evidenced by a significant decrease in discharge scores (p<0.05) across various age groups of women. Bioactive compounds such as essential oils, flavonoids, and curcumin provide antimicrobial, anti-inflammatory, and immunomodulatory activities that help restore vaginal microflora balance. In conclusion, green betel leaf decoction and turmeric were effective in significantly reducing pathological vaginal discharge among adolescent to adult women, in accordance with the long-term treatment objectives.
Co-Authors Anzelina Simbolon, Chindy Aufa Azkia Devina Chandra Dhea Nur Fadhilah Dumartina Hutahuruk Dumartina Hutauruk Elizabet Kristina Purba ElsaNayla Sari Eva Diansari Marbun Febrina Theresa Manurung Jansela Rotua Malau Jon Kenedy Marpaung Julia Susanti Monica Suryani Muhammad Kausar Natanael Priltius Nova Indah Bakara Nurlaili Safitri Rudolfo Zamili Siti Nurbaya Sri Indriyani Sinaga Steven Tandiono Suharyanisa Suharyanisa Supartiningsih - - Theesyah R Sianturi Theesyah R. Sianturi Widia Sari Yanti Musyawarah