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Mini Review: Hubungan Mikrobiom Usus Dengan Kesehatan Manusia Fitria, Murni; Saputra, Anggi; Variyana, Yeni
JFM (Jurnal Farmasi Malahayati) Vol 7, No 2 (2024)
Publisher : Jurnal Farmasi Malahayati (JFM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jfm.v7i2.14348

Mikrobioma usus manusia, sebuah ekosistem kompleks yang terdiri dari jutaan mikroorganisme, telah menjadi fokus penelitian yang signifikan dalam konteks kesehatan manusia. Studi-studi terbaru menunjukkan bahwa komposisi mikrobioma usus dapat mempengaruhi kesehatan secara keseluruhan, termasuk dalam konteks kondisi neuropsikiatrik seperti autisme dan depresi, serta penyakit kardiovaskular. Hubungan antara mikrobioma usus dengan autisme, misalnya, menunjukkan adanya perbedaan dalam kelimpahan bakteri tertentu pada anak-anak dengan autisme dibandingkan dengan yang sehat. Selain itu, gangguan keseimbangan mikroorganisme dalam usus atau disbiosis telah dikaitkan dengan berbagai masalah kesehatan, termasuk penyakit jantung. Metode analisis berupa Next Generation Sequencing (NGS), telah memungkinkan peneliti untuk memahami komposisi mikrobioma usus dan interaksinya dengan kesehatan manusia. Semenatar itu, penggunaan probiotik dan prebiotik berpotensi menangani masalah Kesehatan dengan cara memperbaiki keseimbangan mikrobioma usus. Penelitian lebih lanjut diperlukan untuk memahami lebih dalam hubungan antara mikrobioma usus dan kesehatan manusia, serta potensi terapi probiotik dan prebiotik dalam mengatasi masalah kesehatan yang berkaitan dengan ketidakseimbangan mikrobioma usus.

Analysis of Process Variables Effect on The Efficiency of Soxhletation Extraction of Larvae Oil (Hermetica illucens) using Response Surface Methodology Fitria, Murni; Rhea Alvita, Livia; Ariski Putra, Feby; Variyana, Yeni; Hanifah, Windia
Indonesian Journal of Chemical Analysis (IJCA) Vol. 8 No. 1 (2025): Indonesian Journal of Chemical Analysis
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/ijca.vol8.iss1.art7

Maggot or Black Soldier Fly (BSF) larvae can be used as a source of oil because they have a high lipid content. In this study, the maggot oil extraction process was optimised using the soxhlet method with the assistance of the response surface methodology (RSM) using the Central Composite Design (CCD) research design. Optimization was carried out with variations in the ratio: solvent (1: 7, 1: 10 and 1: 13 g/mL) and extraction time (120, 240 and 360 minutes). The results of the significance test using ANOVA showed that the sample solvent comparison had an insignificant effect (p-value: 0.060). In contrast, the extraction time had a significant effect (p-value: 0.000) on the maggot oil harvest yield. The results of different analyses showed a significant quadratic interaction between the sample solvent comparison (p-value: 0.002) and a significant interaction between the sample solvent comparison and extraction time (p-value: 0.008). The recommended optimal conditions based on optimization using RSM are a combination of a sample solvent ratio of 1:8.5 and an extraction time of 360 minutes with a predicted oil yield of 32.11%. Meanwhile, experimental validation at the recommended optimal conditions produced a yield of 38.68% or greater than the predicted value. The characteristics of the maggot oil obtained had a density of 0.9493 g/mL, a viscosity of 0.92 Pa.s, an air content of 0.0847% w/w, and free fatty acids of 4.56%. The results of GC-MS analysis of maggot oil showed a total of 9 compounds, with the 3 most abundant compounds being oleic acid (52.6%), palmitic acid (24.78%), and lauric acid (12.45%).

Pelatihan Kreatif Pembuatan Sabun Cuci Piring Berbasis Ekstrak Alami Citrus aurantium untuk Peningkatan Keterampilan Guru IPA SMP Kabupaten Pringsewu Lampung Variyana, Yeni; Fitria, Murni; Silmi, Fadian Farisan; Saputra, Anggi; Elsyana, Vida; Hanifah, Windia
Jurnal Pengabdian Pada Masyarakat Vol 10 No 2 (2025): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/jppm.v10i2.1258

Peningkatan permintaan produk rumah tangga yang ramah lingkungan telah memicu perlunya alternatif bahan baku alami, terutama untuk produk pembersih seperti sabun cuci piring. Banyak produk sabun cuci piring komersial mengandung bahan kimia sintetis yang dapat berdampak negatif terhadap lingkungan dan kesehatan, terutama pada pewangi yang digunakan. Sebagai alternatif yang lebih aman dan ramah lingkungan, ekstrak Citrus aurantium dapat digunakan sebagai bahan dasar dalam pembuatan sabun cuci piring karena mengandung senyawa aktif yang memiliki sifat antibakteri dan memiliki aroma segar alami. Kegiatan pengabdian ini bertujuan untuk meningkatkan keterampilan para guru di Kabupaten Pringsewu dalam memanfaatkan bahan lokal dan ramah lingkungan untuk pembuatan sabun cair cuci piring. Pelatihan dilakukan dengan metode partisipatif dan interaktif, melibatkan 40 guru IPA SMP yang tergabung dalam Musyawarah Guru Mata Pelajaran (MGMP) IPA SMP Pringsewu. Kegiatan ini meliputi penyuluhan materi, praktik langsung, dan evaluasi hasil. Hasil pengisian kuisioner pada peserta pelatihan sebanyak 39 orang (97%) menyatakan mampu meningkatkan keterampilan dan pengetahuannya pada pembuatan sabun cuci piring berbasis ekstrak Citrus aurantium dengan baik. Selain meningkatkan keterampilan, kegiatan ini diharapkan dapat mendorong kesadaran peserta akan pentingnya penggunaan bahan alami dan mendukung ekonomi lokal melalui peluang usaha mandiri berbasis produk alami. The growing demand for eco-friendly household products has led to the need for alternative natural raw materials, especially for cleaning products like dishwashing soap. Many commercial dishwashing soaps contain synthetic chemicals that can negatively impact the environment and health, particularly due to the fragrances used. As a safer and more environmentally friendly alternative, Citrus aurantium extract is used as a base ingredient in dishwashing soap production due to its antibacterial active compounds and natural fresh scent. This initiative aims to enhance the skills of teachers in Pringsewu Regency in utilizing local and environmentally friendly materials to make liquid dishwashing soap. The training was conducted using participatory and interactive methods, involving 40 junior high school science teachers from the Science Teachers Working Group (MGMP IPA) in Pringsewu. The activities included material counselling, hands-on practice, and results evaluation. Based on questionnaire responses from participants, 39 out of 40 trainees (97%) reported significant improvement in their skills and knowledge regarding the production of dishwashing soap using Citrus aurantium extract. Besides skill improvement, this activity is expected to raise participants' awareness of the importance of using natural materials and support the local economy through self-sustained business opportunities based on natural products.

Pengembangan Briket Sekam Padi untuk Pemberdayaan Petani Desa Ogan Jaya, Lampung Utara Hidayat, Rahmat; Saputra, Anggi; Fitria, Murni; Feladita, Niken
Jurnal Nusantara Mengabdi Vol. 5 No. 1 (2025): Oktober
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/jnm.v5i1.5717

Purpose: This program aims to empower farmer groups to utilize rice husk waste into alternative fuel through simple briquette-making technology based on the circular economy concept. Methodology/approach: The program employed a participatory approach, involving local communities through several stages, including socialization, environmental education, and technical training on briquette production. The training covered rice husk carbonization, binder preparation, briquette molding, and drying processes. Evaluation was carried out through participant involvement observation, pre-test and post-test assessments, and product quality trials. Results/findings: The results show a significant increase in community knowledge, with over 39% improvement between pre-test and post-test scores. Participants, particularly farmer group members, showed high enthusiasm throughout the activities, and more than 75% successfully produced briquettes independently. A simple briquette press tool was also handed over to the community and proven to be functional and easy to operate. Conclusions: The program effectively enhanced community skills and awareness in renewable energy utilization. Simple technology can convert agricultural waste into economic value while supporting environmental sustainability. Limitations: The short implementation period restricted long-term mentoring and evaluation of sustainability. The number of participants was limited to 15 farmers, reducing generalizability. Moreover, no detailed economic or environmental assessments were conducted, so efficiency and emission impacts remain unquantified. Contribution: This program enhances community capacity in utilizing rice husk waste through simple briquette-making technology. It promotes renewable energy awareness, supports the circular economy, and strengthens collaboration between universities and farmer groups as a replicable model for rural energy innovation.

Pengembangan Briket Sekam Padi untuk Pemberdayaan Petani Desa Ogan Jaya, Lampung Utara Hidayat, Rahmat; Saputra, Anggi; Fitria, Murni; Feladita, Niken
Jurnal Nusantara Mengabdi Vol 5 No 1 (2025): Oktober
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/jnm.v5i1.5717

Purpose: This program aims to empower farmer groups to utilize rice husk waste into alternative fuel through simple briquette-making technology based on the circular economy concept. Methodology/approach: The program employed a participatory approach, involving local communities through several stages, including socialization, environmental education, and technical training on briquette production. The training covered rice husk carbonization, binder preparation, briquette molding, and drying processes. Evaluation was carried out through participant involvement observation, pre-test and post-test assessments, and product quality trials. Results/findings: The results show a significant increase in community knowledge, with over 39% improvement between pre-test and post-test scores. Participants, particularly farmer group members, showed high enthusiasm throughout the activities, and more than 75% successfully produced briquettes independently. A simple briquette press tool was also handed over to the community and proven to be functional and easy to operate. Conclusions: The program effectively enhanced community skills and awareness in renewable energy utilization. Simple technology can convert agricultural waste into economic value while supporting environmental sustainability. Limitations: The short implementation period restricted long-term mentoring and evaluation of sustainability. The number of participants was limited to 15 farmers, reducing generalizability. Moreover, no detailed economic or environmental assessments were conducted, so efficiency and emission impacts remain unquantified. Contribution: This program enhances community capacity in utilizing rice husk waste through simple briquette-making technology. It promotes renewable energy awareness, supports the circular economy, and strengthens collaboration between universities and farmer groups as a replicable model for rural energy innovation.

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