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Pencegahan COVID-19 di Panti dan Pondok melalui Pendidikan dan Perilaku Hidup yang Bersih dan Sehat Muhammad, Iqbal; Putra, Ngakan; Djajalaksana, Susanthy; Sari, Fitri; Falyani , Silvy; Yusdianto, Adrian; Fahmi, Kristia
Jurnal Klinik dan Riset Kesehatan Vol 2 No 2 (2023): Februari 2023
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.02.2.2

Pendahuluan: Penyakit COVID-19 sebagai sumber penularan yang cepat dan telah menjadi pandemi di dunia dan menjadi perhatian penting terutama terhadap populasi rentan seperti anak-anak. Munculnya varian dari virus penyebab penyakit COVID-19 ini pun menjadi ancaman terutama anak-anak, dimana varian delta ditemukan dapat menginfeksi anak yang berusia diantara 1 hingga 14 tahun. Perilaku Hidup Bersih dan Sehat (PHBS) salah satu cara untuk mencegah penyebaran penyakit COVID-19 dan dapat dipraktekan untuk semua kalangan masyarakat, termasuk anak-anak. Tujuan: Penelitian ini bertujuan untuk mencari tingkat keefektivan pendidikan PHBS untuk mencegah COVID-19 pada anak-anak di Panti dan Pondok Kota Malang. Metode: Metode penelitian dengan metode kaji tindak (Action Research) dengan pendekatan program aksi partisipatif (Partisipatory Action Program) pre-test dan post-test yang melibatkan kelompok masyarakat sasaran yaitu 65 orang anak-anak di panti dan pondok Kota Malang. Data dikumpulkan melalui kuesioner yang dilaksanakan sebelum dan setelah penyuluhan berupa edukasi PHBS sebagai pencegahan COVID-19 serta data diolah menggunakan SPSS. Hasil: Hasil penelitian ini adalah terdapat peningkatan pengetahuan responden dimana nilai rata-rata sebelum penyuluhan adalah 85.08 dan meningkat sebesar 94.15 setelah penyuluhan, hasil tersebut berbeda secara signifikan dengan p-value <0.05. Kesimpulan: Terdapat perbedaan signifikan tingkat pengetahuan terhadap PHBS sebagai pencegahan COVID-19 sebelum dan sesudah dilakukan penyuluhan pada anak-anak yatim piatu di panti asuhan. Kata Kunci: PHBS; COVID-19; Edukasi; Pencegahan; Panti dan Pondok.

Exploring How Albumin Supplementation Affects Serum Albumin Levels, CD8+ Lymphocyte Counts, and Interferon Gamma In Rifampicin-Resistant TB Patients Yusdianto, Adrian; Chozin, Iin Noor; Sartono, Teguh Rahayu; Tantular, Rezki; Chilmi, Syahrul; Setijowati, Nanik
Jurnal Respirologi Indonesia Vol 45 No 3 (2025)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v45i3.874

Background: Drug-resistant tuberculosis (DR-TB) remains a global health threat, with increasing cases unresponsive to rifampicin therapy. Diagnosing rifampicin-resistant TB (RR-TB) requires a multidisciplinary approach, in which markers such as interferon-gamma (IFN-ɣ) are useful for diagnosis, monitoring, therapy evaluation, and prognosis. Hypoalbuminemia commonly accompanies TB patients, evidenced by weight loss and reduced serum albumin levels. TB infection stimulates cytokine production, which suppresses albumin synthesis and regulation, affecting both prognosis and treatment success, particularly in RR-TB. This study aimed to evaluate the role of albumin supplementation in improving serum albumin levels, CD8+ lymphocyte counts, and IFN-ɣ levels in RR-TB patients. Methods: This true experimental study with a pre- and post-test control group design was conducted at Saiful Anwar Hospital. Thirty subjects were recruited: 10 healthy individuals (control group), 10 RR-TB patients receiving albumin supplementation (egg white extract) for 30 days (RR-TB + Albumin), and 10 RR-TB patients without supplementation (RR-TB only). Peripheral blood samples were collected before and after anti-TB drug (ATD) and albumin administration. Flow cytometry was used for analysis. Data were analyzed using SPSS and Partial Least Squares (PLS) analysis. Results: Significant differences in albumin and IFN-ɣ levels were observed between the control and RR-TB groups before supplementation. No significant differences were found in CD8+ lymphocyte counts (P=0.402) or IFN-ɣ levels (P=0.390) between supplemented and non-supplemented RR-TB patients. However, albumin levels (P=0.003) and body weight (P=0.014) increased significantly in the supplemented group. Conclusion: Albumin supplementation significantly increases serum albumin levels and body weight in RR-TB patients, but does not significantly affect CD8+ lymphocyte counts or IFN-ɣ levels.

Pencegahan COVID-19 di Panti dan Pondok melalui Pendidikan dan Perilaku Hidup yang Bersih dan Sehat Muhammad, Iqbal; Putra, Ngakan; Djajalaksana, Susanthy; Sari, Fitri; Falyani , Silvy; Yusdianto, Adrian; Fahmi, Kristia
Jurnal Klinik dan Riset Kesehatan Vol 2 No 2 (2023): Februari 2023
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.02.2.2

Pendahuluan: Penyakit COVID-19 sebagai sumber penularan yang cepat dan telah menjadi pandemi di dunia dan menjadi perhatian penting terutama terhadap populasi rentan seperti anak-anak. Munculnya varian dari virus penyebab penyakit COVID-19 ini pun menjadi ancaman terutama anak-anak, dimana varian delta ditemukan dapat menginfeksi anak yang berusia diantara 1 hingga 14 tahun. Perilaku Hidup Bersih dan Sehat (PHBS) salah satu cara untuk mencegah penyebaran penyakit COVID-19 dan dapat dipraktekan untuk semua kalangan masyarakat, termasuk anak-anak. Tujuan: Penelitian ini bertujuan untuk mencari tingkat keefektivan pendidikan PHBS untuk mencegah COVID-19 pada anak-anak di Panti dan Pondok Kota Malang. Metode: Metode penelitian dengan metode kaji tindak (Action Research) dengan pendekatan program aksi partisipatif (Partisipatory Action Program) pre-test dan post-test yang melibatkan kelompok masyarakat sasaran yaitu 65 orang anak-anak di panti dan pondok Kota Malang. Data dikumpulkan melalui kuesioner yang dilaksanakan sebelum dan setelah penyuluhan berupa edukasi PHBS sebagai pencegahan COVID-19 serta data diolah menggunakan SPSS. Hasil: Hasil penelitian ini adalah terdapat peningkatan pengetahuan responden dimana nilai rata-rata sebelum penyuluhan adalah 85.08 dan meningkat sebesar 94.15 setelah penyuluhan, hasil tersebut berbeda secara signifikan dengan p-value <0.05. Kesimpulan: Terdapat perbedaan signifikan tingkat pengetahuan terhadap PHBS sebagai pencegahan COVID-19 sebelum dan sesudah dilakukan penyuluhan pada anak-anak yatim piatu di panti asuhan. Kata Kunci: PHBS; COVID-19; Edukasi; Pencegahan; Panti dan Pondok.

Tuberculous Dactilitis in Young Male, a Rare Case Yusdianto, Adrian; Tantular, Rezki; R. Sugiri, Yani Jane; Rahayu Sartono, Teguh; Rachma Erawati, Dini; Setyo Yudhanto, Hendy
Malang Respiratory Journal Vol. 5 No. 2 (2023): September Edition
Publisher : Universitaas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mrj.2023.005.02.02

Introduction : Chylothorax is an uncommon medical condition caused by the accumulation of chylous fluid in the pleural space. Chylothorax has no predilection for sex or age. The prevalence after various cardiothoracic surgeries is 0.2% to 1%. Mortality and morbidity rates are around 10%. Respiratory distress may occur due to compression of the lung by the accumulated fluid. Management and approaches to treating the condition require multidisciplinary therapy, starting from non-pharmacological, pharmacological, to interventional management. Case Report : A 57-year-old Man patient was referred to the emergency room with chief complaint of shortness of breath. Reduced breathing sound on both lung fields. No previous history of cancer or thoracic surgery were found. X-ray examination had found bilateral pleural effusion. Thoracocentesis and pleural fluid analysis was performed with total of 6800 cc serosanguinous, whitish fluid was extracted from both of the lung. The patient was diagnosed with chylothorax. Lymphangiography and embolization was performed on the leak on left thoracic duct (T10) from right lymph node. Antibiotic was also given to treat the community acquired pneumonia that could be one of the possible etiology on this patient. Dietary modification with low fat diet and Ocreotide was also given to this patient as one of the treatment modalities. Discussion : The diagnosis of Chylothorax on this patient was established based on pleural fluid analysis and evidenced by lymphangiography examination by the presence of a leak in the thoracic lymphatic duct. Various modalities to diagnose this condition have been carried out with inconclusive results. Non-pharmacological, pharmacological and radiological interventions with embolization through lymphangiography are proven to be able to stop leaks and reduce symptoms in this patient. Conclusion : Chyle leak to the pleural space may compress the lung and cause respiratory distress. Combinaton of thoracocentesis, embolization of the leakage, dietary intake modification and administration of ocreotide may help prevent further chylous fluid accumulation.

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