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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Biomedika AJIE (Asian Journal of Innovation and Entrepreneurship) Medika Kartika : Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran Mulawarman Cermin Dunia Kedokteran JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
Suryaningsih, Betty Ekawati
Department Of Dermatology And Venereology, Faculty Of Medicine, Universitas Islam Indonesia, Yogyakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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AKTIVITAS TABIR SURYA SPRAY EKSTRAK DAUN CEMPEDAK (ARTOCARPUS CHAMPEDEN SPRENG) SECARA IN VITRO Putri, Shafa Tasya Nabila; Suryaningsih, Betty Ekawati
Jurnal Kedokteran Mulawarman Vol 12, No 3 (2025): Jurnal Kedokteran Mulawarman
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/jkm.v12i3.23262

Abstract

Background: Sun exposure cause several unwanted effects, including premature aging of the skin and pigmentation One of theadverse effects is skin cancer or melanoma. Currently, skin cancer ranks third with the most cancer cases after breast cancer. Oneway to prevent the adverse effects of ultraviolet (UV) exposure is to use sunscreen. Sunscreen is a cosmetic preparation that canprotect the skin from sun exposure, Sunscreen on the market uses more chemicals, so it often triggers irritation. Indonesia with itswealth of natural resources has many plants that can be used as sunscreen that is safer because the irritating effects caused will belighter. Research is needed on sunscreen from natural ingredients of cempedak leaves which contain flavonoids in the form ofquercetin and function to protect the skin from the adverse effects of ultraviolet (UV) exposureObjectives: To determine the potential of cempedak leaf extract as a sunscreen spray.Method: This study uses a quantitative method of quasi-experimental design with a control group. There were four variations of extract concentrations used, F I; 0,25%, F II; 0,5%, F III; 0,75%, dan F IV; 0,5%+Zn.. Then the absorbance value was checked to determine the Sun Protection Factor (SPF). With data analysis using Kruskal Wallis and Mann WhitneyResult: Based on the results of laboratory tests, there is an increase in Sun Protection Factor (SPF) with every increase in theextract given. The results of the Kruskal Wallis statistical test p=0.000 (p<0.05) showed that there was a significant result betweenthe absorbance value and the variation in the concentration of the extract with the highest SPF result obtained in formula 3 with aresult of 25.79.Conclusion: Cempedak leaf extract has the potential to be used as a sunscreen spray.Keywords: sunscreen, cempedak leaves, flavonoid, spray, ultraviolet
Co-Authors Adi Nugroho Antonius Wibowo, Antonius Farida Juliantina Rachmawaty Hady Anshory Kurnia, Arif Rahmat Melly Rahmawati Noegroho, Trijanto Agoeng Nugrahaningrum, Sulistya Punik Mumpuni Wijayanti Putri, Shafa Tasya Nabila Ramadhan, Tiar Rohmah, Restu Nur Rosmelia Rosmelia Rosmelia Rosmelia Sakinah, Olivia Puteri Tussqyah, Nada Yohanes Widodo Wirohadidjojo