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All Journal E-Jurnal Medika Udayana Warmadewa Minesterium Medical Journal
Anthony Kerans, Fransiscus Fiano
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Biochemistry, Genetics & Molecular Biology Education Health Professions Library & Information Science Medicine & Pharmacology

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THE EFFECT OF NOISE EXPOSURE ON THE AVERAGE NUMBER OF TEMPORAL LOBUS NEURONS IN ADULT WISTAR RATS Suka Astini, Dewa Ayu Agung Alit; Evayanti, Luh Gde; Witari, Ni Putu Diah; Sumadewi, Komang Trisna; Prima Dewi, A.A.A Asri; Anthony Kerans, Fransiscus Fiano; Kurniawati, Ida
E-Jurnal Medika Udayana Vol 13 No 07 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i07.P09

Abstract

Noise is defined as unwanted and disruptive sound, considered an environmental stressor and disturbance. Noise encompasses many aspects of modern communities, including work environments. The damaging effects of noise primarily result from the unrestricted production of free radicals into the auditory organs. Exposure to noise causes various health problems, such as hearing impairment, sleep disturbances, and interference with individual performance. Reactive oxygen species (ROS), also known as free oxygen radicals, are normal by-products of cellular aerobic metabolism. These unstable molecules can damage cellular lipids, proteins, and nucleic acids in DNA if the antioxidant balance is disrupted. Acute and chronic exposure to loud noise generates excessive free radicals and disrupts extra-auditory organs such as the nervous, endocrine, and cardiovascular systems. The purpose of this study is to analyze the relationship between noise exposure and the number of neurons in the temporal lobes of Wistar rats. The research design used is a laboratory experimental design, specifically a pure experimental design, implemented with the randomized posttest-only control group design. The research sample consists of 30 male Wistar rats randomized into 2 groups, control and treatment. The treatment group is exposed to 95dB noise for 4 hours per day for 14 days. The rats are then euthanized, and their brain tissue is fixed with 10% neutral buffered formalin. Assessment is performed using Hematoxylin Eosin staining, and analysis is conducted blindly on the average number of neurons in the rat's temporal lobes. Data is subjected to normality testing using the Shapiro-Wilk test and analyzed using independent t-tests for parametric comparison. The results show a significant difference in the mean number of neurons in the temporal lobes between rats exposed to noise and the control group (p <0.005). The conclusion of this study is that noise affects neuron cells in the temporal lobes. Keywords : noise, temporal lobe, neurons.
Pemberdayaan Kader Posyandu Dalam Stimulasi Perkembangan Bayi Melalui Baby Gym di Banjar Tandang Tri Buana, Desa Batur Tengah, Kintamani Sumadewi, Komang Trisna; Asri Prima Dewi, Anak Agung Ayu; Anthony Kerans, Fransiscus Fiano; Diah Witari, Ni Putu; Suka Astini, Dewa Ayu Agung Alit; Evayanti, Luh Gede; Kurniawati, Ida
Warmadewa Minesterium Medical Journal Vol. 3 No. 3 (2024): September 2024
Publisher : Warmadewa University Press

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Abstract

Gangguan perkembangan pada bayi dan anak menjadi perhatian pemerintah karena dampak yang dapat ditimbulkan. Gangguan perkembangan motorik banyak ditemukan pada bayi usia 3-5 bulan. Gangguan ini berupa keterlambatan perkembangan yang tidak sesuai dengan usianya. Kondisi ini terjadinya karena dipengaruhi oleh berbagai faktor, salah satunya rendahnya stimulus yang diberikan. Berdasarkan wawancara bersama kader Posyandu di Banjar Tandang Tribuana, Desa Batur Tengah, Kecamatan Kintamani, Kabupaten Bangli, didapatkan bahwa pemberian informasi mengenai perkembangan anak masih rendah, pelatihan mengenai pemberian stimulasi bayi dan anak juga masih jarang dilakukan, serta belum pernah dilakukan pelatihan mengenai baby gym. Melihat permasalahan tersebut, maka solusi yang dapat dilakukan antara lain memberikan edukasi mengenai tumbuh kembang serta stimulasi anak berdasarkan usia, dan pelatihan mengenai baby gym yang dapat membantu perkembangan bayi dan anak. Program ini bertujuan untuk meningkatkan pengetahuan mitra mengenai tumbuh kembang anak, stimulasi perkembangan sesuai usia, mengenali keterlambatan perkembangan serta meingkatkan keterampilan mitra dalam melakukan baby gym. Mellalui kegiatan ini didapatkan hasil berupa peningkatan pengetahuan mitra mengenai tumbuh kembang dan stimulasi anak sebesar 51.17%, peningkatan keterampilan mitra dalam memberikan stimulasi serta melalukan baby gym. Kehadiran peserta 100% dengan pastisipasi aktif melalui respon yang diberikan oleh peserta. Kesimpulannya, program ini terlaksana dengan lancar dan dapat memenuhi indikator keberhasilan program yang sudah ditetapkan oleh tim pengabdian.
Co-Authors Asri Prima Dewi, Anak Agung Ayu Evayanti, Luh Gede Ida Kurniawati, Ida Luh Gde Evayanti Ni Putu Diah Witari, Ni Putu Prima Dewi, A.A.A Asri Suka Astini, Dewa Ayu Agung Alit Sumadewi, Komang Trisna Witari, Ni Putu Diah