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All Journal E-Jurnal Medika Udayana Indonesian Journal of Tropical and Infectious Disease Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya
Wulandari, Putu Kintan
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Earth & Planetary Sciences Health Professions Medicine & Pharmacology Public Health

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PROFIL EFEK SAMPING RADIOTERAPI PADA PASIEN KANKER SERVIKS DI RSUP PROF. DR. I. G. N. G. NGOERAH DENPASAR Wulandari, Putu Kintan; Budiana, I Nyoman Gede; Wijaya Surya, I Gede Ngurah Harry; Suwardewa, Tjokora Gde Agung
E-Jurnal Medika Udayana Vol 13 No 4 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i04.P16

Abstract

Kanker serviks merupakan salah satu penyebab kematian terbesar pada wanita di Indonesia. Kanker serviks adalah keadaan tumbuhnya tumor ganas pada sel jaringan serviks. Salah satu pengobatan yang dilakukan sebagai terapi pada kanker serviks adalah radioterapi. Penggunaan radioterapi sendiri tentu memiliki efek samping tersendiri bagi pasien kanker serviks. Tujuan dilakukannya penelitian ini adalah untuk mengetahui profil efek samping radioterapi pada pasien kanker serviks di RSUP Prof. Dr. I.G.N.G. Ngoerah. Penelitian ini menggunakan consecutive sampling sebagai metode pendekatan dengan jumlah minimal 43 sampel. Sample didapatkan berdasarkan pengambilan data dan wawancara kuesioner yang diambil di RSUP Prof. Dr. I.G.N.G. Ngoerah dan data disajikan secara deskriptif. Berdasarkan hasil penelitian, didapatkan sampel sebesar 46 sampel dengan usia pasien berada pada rentang 31-60 tahun (89,1%) dengan persentase stadium tertinggi adalah stadium III-IIIC (58,7%). Efek samping yang dirasakan oleh pasien dengan persentase tertinggi adalah kelelahan (78,3%), diikuti dengan penurunan nafsu makan (63,0%), efek samping lainnya (52,2%), mual (43,5%), diare (43,5%), mulas (37,0%), nyeri BAB dan BAK (32,6%), muntah (8,7%), kerontokan rambut (4,3%), cemas dan perubahan kulit (2,2%). Penggunaan radioterapi sebagai terapi penyembuhan kanker serviks tentu memiliki efek samping bagi penggunanya. Efek samping yang sering dirasakan oleh pasien adalah kelelahan, penurunan nafsu makan, mual, muntah, diare, mulas, nyeri BAB, nyeri BAK, perubahan pada kulit, cemas, kerontokan rambut dan lain-lain.
Epidemiological and Clinical Features of Critical and Non-Critical Elderly COVID-19 Patients in Udayana University Academic Hospital: A Retrospective Study Purnamasidhi, Cokorda Agung Wahyu; Somia, I Ketut Agus; Junior, Darren; Suteja, Richard Christian; Adiputra, I Komang Hotra; Purnama, Giovanca Verentzia; Weisnawa, I Gede Purna; Jerry; Wulandari, Putu Kintan; Shanti, Dewa Ayu Fony Prema; Diksha, I Gusti Ngurah Ariestha Satya
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 1 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i1.43097

Abstract

Elderly COVID-19 patients have been associated with worse outcomes and have been presented with the highest mortality rate. However, studies on the clinical features and the differences between critical and non-critical elderly COVID-19 patients in Indonesia and even other countries are still lacking and rare. In this retrospective study, the epidemiological and clinical features of critical and non-critical elderly COVID-19 patients admitted to Udayana University Academic Hospital between April 2020 and March 2021 were analyzed and then compared. Of the 280 medical records analyzed, 60.7% were male and the median age was 65.0 years old. Based on the medical records, 18.2% of elderly patients met our criteria of critical patients. The most common symptoms presented in both category upon admission included fever and coughing. The most common comorbidity found in critical patients was heart disease and hypertension in non-critical patients. Laboratory results differences included leukocytes, neutrophils, lymphocytes, Neutrophil-to-Lymphocyte Ratio, platelets, SGOT, SGPT, and urea. Only 9.9% of critical patients and 6.1% of non-critical patients were given antiviral therapy. In contrast, 68.6% of critical patients and 76% of non-critical patients were given antibiotics. The mortality rate in critical patients was 70.6% and 0.4% in non-critical patients. Based on the results, a multimodal approach in the treatment of elderly COVID-19 patients is very essential. The higher mortality rate in elderly patients should be able to be reduced by giving early and timely antiviral therapy with the addition of effective choice of drugs.
Mesial Temporal Lobe Epilepsy as a Common but Elusive Case: A Case Report Junior, Darren; Wulandari, Putu Kintan; Harkitasari, Saktivi; Sumardika, I Wayan; Sumadewi, Komang Trisna
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.22259

Abstract

Epilepsy is a common neuronal disorder that could include partial or generalized seizures due to abnormal brain electrical activity. A 32-year-old female patient was presented to the emergency room with a chief complaint of seizure. The seizure semiology started with epigastric pain, which then progressed into sudden speech arrest. Afterward, the patient experienced left-sided head movement followed by jerkings on the left hand. The patient then became unconscious and experienced full body rigidity. Physical examinations, vital signs, and laboratory results showed no abnormalities. Diagnostic assessments only showed unspecific signs of diffuse cerebral edema through a CT Scan and an atrophy of the right hippocampus with a slight increase in FLAIR signal intensity and dilatation of the right lateral ventricle pericornu through MRI. The patient was given phenytoin and folic acid twice daily. The presence of right mesial temporal sclerosis served as a possible cause of epilepsy in this patient despite having several obscurities. The patient showed atypical signs of generalized tonic seizure progression, adult-onset seizures, and increased MRI FLAIR signal intensity. More detailed examinations and constant reports of epilepsy cases are highly needed among physicians to provide more specific methods and tools to diagnose, classify, and treat epilepsy in the future.
Co-Authors Adiputra, I Komang Hotra Cokorda Agung Wahyu Purnamasidhi Diksha, I Gusti Ngurah Ariestha Satya I Ketut Agus Somia I Nyoman Gede Budiana I Wayan Sumardika Jerry Junior, Darren Purnama, Giovanca Verentzia Saktivi Harkitasari, Saktivi Shanti, Dewa Ayu Fony Prema Sumadewi, Komang Trisna Suteja, Richard Christian Suwardewa, Tjokora Gde Agung Weisnawa, I Gede Purna Wijaya Surya, I Gede Ngurah Harry