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All Journal Medical Laboratory Technology Journal JMM (Jurnal Masyarakat Mandiri) Window of Health : Jurnal Kesehatan Sainmatika: Jurnal Ilmiah Matematika dan Ilmu Pengetahuan Alam Jurnal Pengabdian kepada Masyarakat Nusantara Jurnal Laboratorium Khatulistiwa
Lubis, Agnes Felicia
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Lead Contamination in Driver's Blood and Its Effects on Erythrocytes, Leukocytes, and Platelets as A Biomarker Mariadi, Pra Dian; Lubis, Agnes Felicia; Septie Ch, Lidwina
Sainmatika: Jurnal Ilmiah Matematika dan Ilmu Pengetahuan Alam Vol. 20 No. 2 (2023): Sainmatika : Jurnal Ilmiah Matematika dan Ilmu Pengetahuan Alam
Publisher : Universitas PGRI Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31851/sainmatika.v20i2.13010

Abstract

Lead as a component of air pollution has broad toxic effects and can be detrimental to humans, such as causing abnormalities in kidney function, digestive tract, nervous system, and hematopoietic disorders. Many people carry out their activities on the highway, one of which is an Angkot driver. Drivers who work on the road daily get direct exposure to air pollution, especially from lead (Pb). Therefore they are very vulnerable to the negative effects of lead (Pb). This study aimed to measure blood lead levels as a biomarker of lead contamination in a driving group in Palembang City. The subjects were drivers who had been working for more than 20 years (average 28 years) and the average age was 58 years. Testing blood lead levels using the APHA method and examining erythrocytes leukocytes and platelets using the impedance method and correlation test using the Spearman test. Based on the results of this study, there is a relationship between blood lead levels and erythrocyte (significance: 0.0019) and leukocyte (significance: 0.002) values, but there is no relationship between blood lead levels and platelet values (significance: 0.4), while blood lead levels in drivers are still within the threshold limit (average: 14.9804 µg/L).
Analysis of COVID-19 Antibodies in Patients Who Have Been Vaccinated With Non-Vaccinated Patients with Confirmed COVID-19 Life Hutabarat, Mustika Sari H; Lubis, Agnes Felicia; Sinaga, Hotman
Medical Laboratory Technology Journal Vol. 10 No. 2 (2024): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v10i2.607

Abstract

COVID-19 immunization is a government initiative to prevent transmission and reduce the incidence of disease and death associated with the SARS-CoV-2 virus. Although the SARS-CoV-2 virus is no longer a significant threat, older adults with comorbidities or people who are immunosuppressed should remain vigilant by maintaining a distance of at least one meter from others, covering their mouths with their elbows when coughing or sneezing, washing their hands regularly, and wearing masks. However, many groups oppose vaccination for various reasons, including the perception that the COVID-19 vaccine is less effective and efficient in preventing SARS-CoV-2 virus infection. This study compared COVID-19 antibody titers in participants who had arrived, without mentioning the vaccine brand, with those who had not yet arrived but had a history of SARS-CoV-2 infection. This study design used a cross-sectional study; the number of samples in the study was 34, the location of this study was the Palembang Public Health Laboratory Center, and the statistical test in the study used the Independent T-test. The study results indicate that the mean antibody titer in the vaccinated group was 98.123. In contrast, in the unvaccinated group, it was 70.641, demonstrating a statistically significant difference with a p-value of 0.000. Further research suggests whether there is a relationship between antibody titers in subjects who have been vaccinated for the second and third time with a history of exposure to the COVID-19 virus.
Analisa Kadar Timbal Dalam Darah Dengan Kadar Hemaglobin Dan Hematokrit Pada Supir di Kota Palembang Lubis, Agnes Felicia; Ch, Lidwina Septie
Jurnal Laboratorium Khatulistiwa Vol 8, No 1 (2024): November 2024
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v8i1.1567

Abstract

Palembang City is a major urban center located on the island of Sumatra that has experienced substantial growth and development. The rapid increase in population and industrial activity has led to widespread contamination of water, food, and beverages with heavy metals. This is worsened by other variables, including smoking habits and work-related issues. At now, there is a limited number of papers that examine blood as a biomarker for lead contamination, particularly in Palembang City. These articles mostly focus on study participants that are very likely to be exposed, such as drivers. The objective of this study was to evaluate the blood lead levels in a cohort of drivers in Palembang City as an indicator of lead pollution. The participants in this study were drivers, with an average age of 58 years, who had accumulated more than 20 years of work experience (average 28 years). Utilizing the APHA technique, quantifying blood lead concentrations, and employing the impedance method and Spearman test to establish a correlation between the results, evaluating hemoglobin and hematocrit levels. The research findings indicate a correlation between blood lead levels and hemoglobin values (significance: 0.037) as well as hematocrit (significance: 0.039). The mean blood lead concentrations in drivers remain below the threshold of 14.9804 µg/L. The investigation conducted indicates a clear association between the levels of lead in the blood and the values of hemoglobin and hematocrit in the blood of drivers in Palembang City. A strong association was seen between blood lead levels and hemoglobin and hematocrit values
EDUKASI KESEHATAN MENGENAI PENTINGNYA MELAKUKAN PEMERIKSAAN LABORATORIUM DARAH DAN URINE PADA IBU HAMIL TRIMESTER II DAN III Lubis, Agnes Felicia; Sari, Anjelina Puspita; Romlah, Romlah; Hutabarat, Mustika Sari; Haiti, Margareta
JMM (Jurnal Masyarakat Mandiri) Vol 8, No 6 (2024): Desember
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v8i6.27650

Abstract

Abstrak: Ibu hamil dan janinnya memiliki risiko lebih tinggi untuk mengalami masalah seperti diabetes gestasional dan preeklamsia, sehingga sangat penting untuk mengidentifikasi masalah ini sejak dini guna melindungi kesehatan ibu dan anak. Hal ini terutama berlaku pada trimester kedua dan ketiga kehamilan. Isu: Upaya untuk menurunkan angka kesakitan dan kematian ibu terus menghadapi masalah kesehatan ibu hamil pada trimester kedua dan ketiga. Karena kurangnya tanda-tanda awal yang jelas, banyak kasus masalah kehamilan seperti diabetes gestasional dan preeklamsia tidak terdiagnosis hingga berlanjut. Untuk mengurangi terjadinya kesulitan selama kehamilan, PkM bertujuan untuk meningkatkan kesadaran di kalangan petugas kesehatan masyarakat dan ibu hamil tentang pentingnya perawatan prenatal rutin. Metode: konseling ibu hamil tentang tanda-tanda bahaya kehamilan dan manfaat pemeriksaan gula darah dan protein urin, yang dilakukan pada trimester kedua dan ketiga di PMB Lismarini, dan konsultasi dengan ibu hamil yang memiliki hasil pemeriksaan abnormal tentang pola makan dan gaya hidup sehat. Sasaran yang menjadi mitra merupakan ibu hamil trimester II dan III sejumlah 45 Orang... Temuan: peningkatan pemahaman tentang indikator risiko kehamilan di kalangan ibu hamil diamati dalam temuan pasca-tes (85%), dengan 3,3% ibu hamil memiliki kadar gula darah di atas normal dan 9,7% menunjukkan proteinuria. Fasilitas kesehatan tingkat lanjut diinstruksikan untuk melakukan pemeriksaan lanjutan pada ibu hamil yang hasilnya berada di luar kisaran biasanya.Abstract: Pregnant women and their unborn children are at increased risk for problems like gestational diabetes and preeclampsia, so it is crucial to identify these issues early on to protect both mother and child health. This is particularly true in the second and third trimesters of pregnancy. Issue: Efforts to decrease maternal morbidity and mortality continue to face the problem of pregnant women's health during the second and third trimesters. Due to the lack of obvious early signs, many cases of pregnancy problems such gestational diabetes and preeclampsia go undiagnosed until they progress. In order to reduce the occurrence of difficulties during pregnancy, PkM aims to raise awareness among community health professionals and pregnant women about the significance of routine prenatal care. Methods: counseling pregnant women on danger signs of pregnancy and the benefits of blood sugar and urine protein testing, which are done during the second and third trimesters at PMB Lismarini, and consulting with pregnant women who have abnormal test results about healthy diet and lifestyle. The target partners are pregnant women in the second and third trimesters, totaling 45 people. Findings: an improvement in understanding of pregnancy risk indicators among pregnant women was observed in the post-test findings (85%), with 3.3% of pregnant women having blood sugar levels over normal and 9.7% demonstrating proteinuria. Advanced health facilities were instructed to do follow-up exams on pregnant women whose results were outside the usual range.
Skrining Penyakit Degeneratif Pada Usia Produktif di Kelurahan Sukarami Sumatera Selatan Lubis, Agnes Felicia; Hutabarat, Mustika Sari H; Nur Aeni, Maria; Sudarmi, Lusia
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 4 No. 4 (2023): Jurnal Pengabdian kepada Masyarakat Nusantara (JPkMN)
Publisher : Lembaga Dongan Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55338/jpkmn.v4i4.2128

Abstract

Penyakit degeneratif merupakan penyakit yang sulit dideteksi karena banyak orang yang tidak mengetahuinya atau tidak menunjukkan gejala apa pun. Karena banyak orang tidak menyadari atau tidak menunjukkan gejala yang jelas, penyakit degeneratif seringkali sulit dideteksi. Penurunan fungsi organ tubuh menyebabkan penyakit degeneratif. Hipertensi, jantung koroner, diabetes mellitus, asam urat, dan lain-lain adalah beberapa contoh penyakit degeneratif.  Diabetes mellitus (DM) adalah salah satu penyakit jangka panjang yang paling umum dan merupakan penyebab kematian keempat tertinggi di negara-negara berkembang. Pada tahap yang lebih parah atau ketika terjadi komplikasi, orang seringkali menyadari adanya penyakit degeneratif. Tujuan dari pengabdian masyarakat ini adalah melakukan skrining serta mengedukasi masyarakat tentang bahaya dan pencegahan penyakit degeneratif. Mitra kegiatan ini merupakan masyarakat lorong suka senang kecamatan Sukarami yang dibantu oleh ketua RT setempat dalam memberikan informasi mengenai kegiatan ini. Kegiatan dilaksanakan pada tanggal 30 Juli 2023 di kecamatan Sukarami, Lorong Suka Senang, Jl. Kolonel H. Barlian KM.7. Kegiatan dilakukan dengan skrining hipertensi dan diabetes dengan melakukan pengukuran berat badan, tinggi badan, pemeriksaan tekanan darah serta pemeriksaan gula darah. Kegiatan ini memberikan dampak positif bagi para peserta karena selain melakukan pemeriksaan gula darah mereka dapat menyampaikan keluhan yang di rasakan dan memberikan penjelasan untuk menjawab pertanyaan tentang keluhan tersebut. Kesimpulan dari kegiatan ini agar masyarakat menjadi sadar akan bahaya penyakit degeneratif dan mampu melakukan upaya preventif untuk mengalahkannya.
Effect of Lead Exposure on AST Enzyme in Individuals Who Smoke Lubis, Agnes Felicia; Christyawardani, Lidwina Septie; Lusia Sudarmi
Window of Health : Jurnal Kesehatan Vol 8 No 3 (July 2025)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/woh.vi.1601

Abstract

Cigarettes are one of the consumer products that are popular with the public. The composition of cigarettes includes tobacco, cloves, and other additives. One of the additives that is often used is lead. Lead can also be carcinogenic, meaning it can cause cancer. Exposure to lead in active smokers can cause various health hazards, especially those related to liver damage. Increased levels of lead in the body of smokers can cause liver cell damage, which can be reflected in increased levels of the enzyme AST (aspartate aminotransferase) in the blood. This study aims to see the effect of this heavy metal on the levels of the Aspartate Aminotransferase Enzyme in Individuals Who Smoke. This research method uses a descriptive introduction with a simple random sampling approach. The subjects of this study consisted of 10 people who were drivers with an average age of 25 years who had been smoking for 5-8 years. Blood lead levels were measured using the APHA method, and AST enzyme levels were measured using the IFCC method. The results showed that there was no relationship between blood lead levels and AST levels in smokers and blood lead levels (significance: 0.066). The average lead level in the blood of active smokers is still below the threshold, which is 34.1437 µg/L (100–250 µg/L). Suggestions for further research are to conduct research to see the relationship between lead levels and Alanine Aminotransferase (ALT) enzyme levels in online motorcycle taxi drivers and cleaners in the city of Palembang.
Co-Authors Ch, Lidwina Septie Christyawardani, Lidwina Septie Haiti, Margareta Hutabarat, Mustika Sari Hutabarat, Mustika Sari H Lusia Sudarmi Nur Aeni, Maria Pra Dian Mariadi, Pra Dian Romlah Sari, Anjelina Puspita Septie Ch, Lidwina Sinaga, Hotman Sudarmi, Lusia