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Lead Contamination in Driver's Blood and Its Effects on Erythrocytes, Leukocytes, and Platelets as A Biomarker Mariadi, Pra Dian; Lubis, Agnes Felicia; Septie Ch, Lidwina
Sainmatika: Jurnal Ilmiah Matematika dan Ilmu Pengetahuan Alam Vol. 20 No. 2 (2023): Sainmatika : Jurnal Ilmiah Matematika dan Ilmu Pengetahuan Alam
Publisher : Universitas PGRI Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31851/sainmatika.v20i2.13010

Abstract

Lead as a component of air pollution has broad toxic effects and can be detrimental to humans, such as causing abnormalities in kidney function, digestive tract, nervous system, and hematopoietic disorders. Many people carry out their activities on the highway, one of which is an Angkot driver. Drivers who work on the road daily get direct exposure to air pollution, especially from lead (Pb). Therefore they are very vulnerable to the negative effects of lead (Pb). This study aimed to measure blood lead levels as a biomarker of lead contamination in a driving group in Palembang City. The subjects were drivers who had been working for more than 20 years (average 28 years) and the average age was 58 years. Testing blood lead levels using the APHA method and examining erythrocytes leukocytes and platelets using the impedance method and correlation test using the Spearman test. Based on the results of this study, there is a relationship between blood lead levels and erythrocyte (significance: 0.0019) and leukocyte (significance: 0.002) values, but there is no relationship between blood lead levels and platelet values (significance: 0.4), while blood lead levels in drivers are still within the threshold limit (average: 14.9804 µg/L).
Analysis of COVID-19 Antibodies in Patients Who Have Been Vaccinated With Non-Vaccinated Patients with Confirmed COVID-19 Life Hutabarat, Mustika Sari H; Lubis, Agnes Felicia; Sinaga, Hotman
Medical Laboratory Technology Journal Vol. 10 No. 2 (2024): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v10i2.607

Abstract

COVID-19 immunization is a government initiative to prevent transmission and reduce the incidence of disease and death associated with the SARS-CoV-2 virus. Although the SARS-CoV-2 virus is no longer a significant threat, older adults with comorbidities or people who are immunosuppressed should remain vigilant by maintaining a distance of at least one meter from others, covering their mouths with their elbows when coughing or sneezing, washing their hands regularly, and wearing masks. However, many groups oppose vaccination for various reasons, including the perception that the COVID-19 vaccine is less effective and efficient in preventing SARS-CoV-2 virus infection. This study compared COVID-19 antibody titers in participants who had arrived, without mentioning the vaccine brand, with those who had not yet arrived but had a history of SARS-CoV-2 infection. This study design used a cross-sectional study; the number of samples in the study was 34, the location of this study was the Palembang Public Health Laboratory Center, and the statistical test in the study used the Independent T-test. The study results indicate that the mean antibody titer in the vaccinated group was 98.123. In contrast, in the unvaccinated group, it was 70.641, demonstrating a statistically significant difference with a p-value of 0.000. Further research suggests whether there is a relationship between antibody titers in subjects who have been vaccinated for the second and third time with a history of exposure to the COVID-19 virus.
Analisa Kadar Timbal Dalam Darah Dengan Kadar Hemaglobin Dan Hematokrit Pada Supir di Kota Palembang Lubis, Agnes Felicia; Ch, Lidwina Septie
Jurnal Laboratorium Khatulistiwa Vol 8, No 1 (2024): November 2024
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v8i1.1567

Abstract

Palembang City is a major urban center located on the island of Sumatra that has experienced substantial growth and development. The rapid increase in population and industrial activity has led to widespread contamination of water, food, and beverages with heavy metals. This is worsened by other variables, including smoking habits and work-related issues. At now, there is a limited number of papers that examine blood as a biomarker for lead contamination, particularly in Palembang City. These articles mostly focus on study participants that are very likely to be exposed, such as drivers. The objective of this study was to evaluate the blood lead levels in a cohort of drivers in Palembang City as an indicator of lead pollution. The participants in this study were drivers, with an average age of 58 years, who had accumulated more than 20 years of work experience (average 28 years). Utilizing the APHA technique, quantifying blood lead concentrations, and employing the impedance method and Spearman test to establish a correlation between the results, evaluating hemoglobin and hematocrit levels. The research findings indicate a correlation between blood lead levels and hemoglobin values (significance: 0.037) as well as hematocrit (significance: 0.039). The mean blood lead concentrations in drivers remain below the threshold of 14.9804 µg/L. The investigation conducted indicates a clear association between the levels of lead in the blood and the values of hemoglobin and hematocrit in the blood of drivers in Palembang City. A strong association was seen between blood lead levels and hemoglobin and hematocrit values
Skrining Penyakit Degeneratif Pada Usia Produktif di Kelurahan Sukarami Sumatera Selatan Lubis, Agnes Felicia; Hutabarat, Mustika Sari H; Nur Aeni, Maria; Sudarmi, Lusia
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 4 No. 4 (2023): Jurnal Pengabdian kepada Masyarakat Nusantara (JPkMN)
Publisher : Lembaga Dongan Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55338/jpkmn.v4i4.2128

Abstract

Penyakit degeneratif merupakan penyakit yang sulit dideteksi karena banyak orang yang tidak mengetahuinya atau tidak menunjukkan gejala apa pun. Karena banyak orang tidak menyadari atau tidak menunjukkan gejala yang jelas, penyakit degeneratif seringkali sulit dideteksi. Penurunan fungsi organ tubuh menyebabkan penyakit degeneratif. Hipertensi, jantung koroner, diabetes mellitus, asam urat, dan lain-lain adalah beberapa contoh penyakit degeneratif.  Diabetes mellitus (DM) adalah salah satu penyakit jangka panjang yang paling umum dan merupakan penyebab kematian keempat tertinggi di negara-negara berkembang. Pada tahap yang lebih parah atau ketika terjadi komplikasi, orang seringkali menyadari adanya penyakit degeneratif. Tujuan dari pengabdian masyarakat ini adalah melakukan skrining serta mengedukasi masyarakat tentang bahaya dan pencegahan penyakit degeneratif. Mitra kegiatan ini merupakan masyarakat lorong suka senang kecamatan Sukarami yang dibantu oleh ketua RT setempat dalam memberikan informasi mengenai kegiatan ini. Kegiatan dilaksanakan pada tanggal 30 Juli 2023 di kecamatan Sukarami, Lorong Suka Senang, Jl. Kolonel H. Barlian KM.7. Kegiatan dilakukan dengan skrining hipertensi dan diabetes dengan melakukan pengukuran berat badan, tinggi badan, pemeriksaan tekanan darah serta pemeriksaan gula darah. Kegiatan ini memberikan dampak positif bagi para peserta karena selain melakukan pemeriksaan gula darah mereka dapat menyampaikan keluhan yang di rasakan dan memberikan penjelasan untuk menjawab pertanyaan tentang keluhan tersebut. Kesimpulan dari kegiatan ini agar masyarakat menjadi sadar akan bahaya penyakit degeneratif dan mampu melakukan upaya preventif untuk mengalahkannya.