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All Journal Jurnal Riset Kefarmasian Indonesia Jurnal Insan Farmasi Indonesia
Loimalitna, Pricillya Maria
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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PENGARUH KONSENTRASI ETANOL TERHADAP RENDEMEN EKSTRAK DAUN JATI BELANDA (Guazuma ulmifolia) DAN DAUN SUKUN (Artocarpus altilis) Falestin , Senny Listy Kartika; Efrilia, Mega; Chandra, Pra Panca Bayu; Loimalitna, Pricillya Maria; Sabrina, Alifa
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2093

Abstract

Dutch teak leaves and breadfruit leaves are natural ingredients used  medicine. The secondary metabolite content Dutch teak and breadfruit leaf extracts believed to play a role in providing medicinal properties natural ingredients. Extracting natural ingredients with ethanol solvent can affect the yield. The aim research was to determine effect of variations in solvent concentration on the yield of Dutch teak and breadfruit leaf extracts. This research includes determination, collection and preparation of simplicia, making simplicia, extracts and determining the extract yield. This study, 20 grams of Dutch teak and breadfruit leaf powder were extracted with different solvent concentrations, namely 70%, 90% and 95% ethanol using maceration method. Replication was carried out in each solvent 3 times. Analyzed using descriptive methods and processed with Statistical Product and Service Solutions (SPSS) 26 tool. The highest yield research results were obtained from 70% ethanol extract of Dutch teak leaves (Guazuma ulmifolia) with an average of 2.79% ± 0.21 and extract ethanol 90% breadfruit leaves (Artocarpus altilis) with an average of 10.33% ± 0.33. The results the two way anova test, obtained a sig = 0.000 < 0.05 so that there were significant differences between plant groups and ethanol concentration the extract yield results.
PENETAPAN KADAR RENDEMEN DAN FLAVONOID EKSTRAK DAUN KELOR (Moringa oleifera) SECARA SPEKTROFOTOMETRI UV-VIS Whardhani, Sabrina K; Handayani, Indri Astuti; Loimalitna, Pricillya Maria; Chandra, Pra Panca Bayu; Christian, Yulius Evan
Jurnal Riset Kefarmasian Indonesia Vol. 7 No. 3 (2025): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/v7i3.773

Abstract

Moringa leaves (Moringa oleifera L.) are herbal plants known to contain bioactive compounds such as flavonoids and phenolics, which have potential as natural antioxidants and can be utilized in the development of herbal-based pharmaceutical preparations. This study aimed to determine the organoleptic characteristics and the total flavonoid content of 96% ethanol extract of Moringa leaves. The extraction process was carried out using the maceration method with 96% ethanol solvent on 1 kg of fresh Moringa leaves. The leaves were dried into simplicia powder weighing 126.22 g, then macerated for 3 days with stirring every 24 hours. The filtrate was evaporated using a rotary evaporator at 40°C to obtain a thick extract, yielding 7.01% with a native DER value of 14.26. The organoleptic characteristics showed that the extract had the typical odor of Moringa leaves, a bitter taste, and a greenish-brown color. The determination of flavonoid content was conducted using the aluminium chloride colorimetric method with quercetin as the standard, and measurements were performed at a maximum wavelength of 450 nm. The calibration curve showed a linear relationship between quercetin concentration and absorbance with the regression equation y = 0.0163x – 0.0789 and R² = 0.9986. The analysis results showed that the total flavonoid content of the 96% ethanol extract of Moringa leaves was 1203.78 ± 2.98 mg/100 g. With its high flavonoid content, Moringa leaf extract has the potential to be developed as a natural antioxidant in herbal-based pharmaceutical formulations.
Co-Authors Chandra, Pra Panca Bayu Efrilia, Mega Falestin , Senny Listy Kartika Handayani, Indri Astuti Sabrina, Alifa Whardhani, Sabrina K Yulius Evan Christian