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All Journal Bioedukasi: Jurnal Pendidikan Biologi Agroteknika
Pratama, Mohammad Indra
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Energy Engineering Mechanical Engineering

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ANALISIS KANDUNGAN METABOLIK SEKUNDER PADA DAUN KENIKIR (Cosmos Caudatus Kunth.) DENGAN PELARUT METANOL, ETANOL, DAN ETIL ASETAT Masitah, Masitah; Pribadi, Teguh; Pratama, Mohammad Indra; Harrist, Reynaldi Ferdhani; Sari, Prita Asminitya; Dianita, Feby; Setiawan, Volta Kellik
BIOEDUKASI: Jurnal Pendidikan Biologi Vol 14, No 2 (2023): BIOEDUKASI, NOVEMBER 2023
Publisher : UNIVERSITAS MUHAMMADIYAH METRO

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/bioedukasi.v14i2.7805

Abstract

Cosmos Caudatus Kunth. is one of the most commonly found medicinal plants.   Cosmos leaves contain phytochemical compounds such as terpenoids, fatty acids, flavonoids, alkaloids, tannins, and saponins. This study aims to determine the effect of differences in methanol, ethanol, and ethyl acetate solvents on the phytochemical tests of  Cosmos leaf samples. The study was conducted in the Biology Education Laboratory, Faculty of Teacher Training and Education, Mulawarman University, as well as the Organic Chemistry Laboratory, Faculty of Mathematics and Natural Sciences, Mulawarman University. Qualitative phytochemical screening is conducted by assessing the solubility qualities of the substances. The findings from the examination of secondary metabolic chemicals indicate that the methanol extract derived from Cosmos leaves comprises alkaloids, triterpenoids, flavonoids, phenolics, and quinones. While the ethanol extract of Cosmos leaves contains alkaloids, flavonoids, saponins, phenolics, and quinones. There is an ethyl acetate extract of Cosmos leaves, alkaloids, steroids, flavonoids, phenolics, and quinones.
ANALISIS EKSTRAK ETANOL DAUN GAHARU (Aquilaria malaccensis) TERHADAP PENEBALAN ALVEOLI DAN LEUKOSIT DIFERENSIAL MENCIT (Mus musculus) YANG DI INDUKSI KARBAMAT SECARA IN VIVO Pratama, Mohammad Indra; Jailani, Jailani; Nasution, Ruqoyyah; Awang Sari, Eadvin Rodrinda; Pribadi, Teguh
Bioedukasi Jurnal Pendidikan Biologi Vol 15, No 2 (2024): BIOEDUKASI, NOVEMBER 2024
Publisher : UNIVERSITAS MUHAMMADIYAH METRO

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/bioedukasi.v15i2.10371

Abstract

The research aimed to look at the effect of induction. The effect of administering ethanol extract of gaharu leaves (Aquilaria malaccensis Lamk) on the histopathological picture of the lungs of white mice (Mus musculus) induced by carbamate class insecticides. The method used was truly experimental, carbamate induction via the intramuscular route with a dose of 14.4 Mg/BW and agarwood extract administered via the oral route with doses of 100, 200, and 300 Mg/BW, the duration of each treatment was 15 days. After treatment, preparations were made of the lungs using the paraffin block staining method with hematoxylin-eosin, the thickness of the alveolar septa and the presence of alveolar macrophages were measured. The results of the research showed that there was a thickening of the alveolar septa after induction of carbamate insecticide at a dose of 14.4 mg/BW with an average thickness of 21.62 µm compared to the healthy control group of 12.61, in addition to an increase in the percentage of neutrophils of 48.66 compared to the healthy controls of 23.33 which was caused by inflammation in the mice's bodies. , a decrease in the thickness of alveolar septa was caused by the administration of ethanol extract of agarwood leaves at a dose of 100/200/300 mg/BW with an average thickness of 15.18, 13.73, 15.57 µm compared to the negative control of 21.62 µm. Thus, it can be concluded that there is an influence of agarwood leaf extract on lung histopathology -lungs of mice induced with carbamate class insecticides.
Eksplorasi Potensi Daun Singkil (Premna corymbosa Rottl. et Willd) sebagai Teh Herbal: Studi Perbandingan Kandungan Bioaktif Ekstrak dan Rendaman Daun Pribadi, Teguh; Zakiyyah, Zulfa; Zahra, Suci; Hadi , Ingghrid Ranesti Clarita; Masitah, Masitah; Pratama, Mohammad Indra
Agroteknika Vol 7 No 4 (2024): Desember 2024
Publisher : Green Engineering Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55043/agroteknika.v7i4.313

Abstract

Makanan maupun minuman alami yang mengandung zat antioksidan sampai saat ini tergolong cukup banyak termasuk dalam tanaman singkil. Spesies premna atau singkil diketahui memiliki kandungan antioksidan yang tinggi, di mana kandungan flavonoid dan fenolat memiliki peran pengkontribusi yang cukup penting dalam memberikan kadar antioksidan dalam tanaman singkil. Tujuan penelitian untuk mengetahui potensi aktivitas antioksidan pada ekstrak dan rendaman daun singkil guna melihat potensi daun singkil sebagai teh herbal. Penelitian dikaji menggunakan penelitian eksperimental laboratorium. Penelitian dilakukan di Laboratorium Farmakologi dan Laboratorium Pasca Panen dan Pengemasan Universitas Mulawarman Samarinda. Penelitian dilaksanakan pada bulan Juni-Juli 2024. Hasil menunjukkan bahwasanya ekstrak daun singkil mengandung flavonoid sebesar 248,46 mg Qe/g, dua kali lebih tinggi dibandingkan rendaman yang mengandung 156,48 mg Qe/g. Hasil uji aktivitas antioksidan menggunakan metode DPPH menunjukkan bahwasannya nilai IC50 pada sampel rendaman daun singkil sebesar 225,37 ppm memiliki intensitas sedang, sedangkan nilai IC50 pada sampel ekstrak daun singkil sebesar 43,37 ppm memiliki intensitas sangat aktif. Penelitian ini menunjukkan bahwa ekstrak pada daun singkil (Premna corymbosa Rottl. et Willd) memiliki kadar aktivitas antioksidan yang lebih kuat dibandingkan rendaman daun singkil, sehingga daun singkil berpotensi untuk dijadikan teh yang kaya akan antioksidan.
Co-Authors Awang Sari, Eadvin Rodrinda Dianita, Feby Hadi , Ingghrid Ranesti Clarita Harrist, Reynaldi Ferdhani Jailani Jailani Masitah Masitah Nasution, Ruqoyyah Sari, Prita Asminitya Setiawan, Volta Kellik Teguh Pribadi Zahra, Suci Zakiyyah, Zulfa