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All Journal Folia Medica Indonesiana Mitra Raflesia (Journal of Health Science) Jurnal Ilmiah Pharmacy Jurnal Sanitasi Profesional Indonesia International Journal of Health Sciences Jurnal Pengabdian Masyarakat (Jupemas) Journal Fatmawati Laboratory & Medical Science
Dewi, Devi Cynthia
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Journal : Mitra Raflesia (Journal of Health Science)

 1 
ANALISIS KADAR Immunoglobulin G Dan Immunoglobulin M TERHADAP PENDERITA DEMAM BERDARAH DENGUE (DBD) DI RS. HARAPAN DAN DOA KOTA BENGKULU Dewi, Devi Cynthia
Mitra Raflesia (Journal of Health Science) Vol 16, No 2 (2024)
Publisher : LPPM STIKES BHAKTI HUSADA BENGKULU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51712/mitraraflesia.v16i2.414

Abstract

ABSTRAKLatar Belakang : Penyakit DBD merupakan salah satu masalah kesehatan di Indonesia yang jumlah penderitanya cenderung meningkat dan penyebarannya semakin luas. Infeksi virus dengue dapat menyebabkan Demam Berdarah Dengue (DBD). Agent penularannya yaitu nyamuk betina yang terinfeksi terutama nyamuk Aedes aegypti dan Aedes albopictus melalui gigitan nyamuk yang terinfeksi. Penelitian ini bertujuan untuk menganalisis kadar IgG dan IgM pada penderita Deman berdarah dengue (DBD) di RS. Harapan dan Doa Kota Bengkulu. Metode : Penelitian ini menggunakan jenis penelitian analisis deskriptif dengan pendekatan studi literatur. Data diolah secara analisis univariat dan bivariate. Gambaran dari hasil Immunoglobulin G dan Immunoglobulin M yang diperoleh yaitu 5 sampel (16,7%) dengan hasil Immunoglobulin G(-) dan Immunoglobulin M(+),15 sampel (38,4%) dengan hasil Immunoglobulin G(+) dan Immunoglobulin M (-),11 sampel (31,2%) dengan hasil Immunoglobulin G(+) dan Immunoglobulin M (+),6 sampel (14,2%) dengan hasil Immunoglobulin G (-) dan IgM (-). Hasil : Berdasarkan hasil yang diperoleh, terdapat hasil IgG (-) dan IgM (+) pada 5 sampel (28%), serta hasil IgG (+) dan IgM (-) pada 10 sampel (42%) dan 15 (37%). sampel. Dengan IgG (-) dan IgM (-). Berdasarkan jenis kelamin, 15 orang (73,8%) berjenis kelamin laki-laki dan 45 orang (26,3%) berjenis kelamin perempuan. Diketahui nilai X2 yang dihitung dari hasil statistik chi-square = 45,3> X2 tabel =5,954 dengan nilai r = 0,000 (< 0,05). Simpulan : Hasil: Berdasarkan hasil penelitian, IgG dan IgM pada pasien DBD paling banyak ditemukan berdasarkan hasil analisa serologi IgG (+) dan IgM (-) dengan penyakit DBD sekunder, dan terdapat pada pasien lainnya. Penderita demam berdarah lebih sering adalah laki-laki dibandingkan perempuan.Kata Kunci : DBD, Analisis Kadar IgG, Analisis Kadar IgM.  ABSTRACTBackground : DHF is one of the health problems in Indonesia The number of sufferers tends to increase and the spread becomes wider. Dengue virus infection can cause Dengue Hemorrhagic Fever (DHF). The transmission agent is infected female mosquitoes, especially Aedes aegypti and Aedes albopictus mosquitoes through the bite of an infected mosquito. This study aims to analyze IgG and IgM levels in dengue hemorrhagic fever (DHF) sufferers in hospitals. Hopes and Prayers of the City of Bengkulu. Methods : This research uses descriptive analysis research with a literature study approach. Data were processed using univariate and bivariate analysis. An overview of the Immunoglobulin G and Immunoglobulin M results obtained were 5 samples (16.7%) with Immunoglobulin G(-) and Immunoglobulin M(+) results, 15 samples (38.4%) with Immunoglobulin G(+) and Immunoglobulin results M (-), 11 samples (31.2%) with results of Immunoglobulin G (+) and Immunoglobulin M (+), 6 samples (14.2%) with results of Immunoglobulin G (-) and IgM (-). Results Based on the results obtained, there were IgG (-) and IgM (+) results in 5 samples (28%), as well as IgG (+) and IgM (-) results in 10 samples (42%) and 15 (37%). sample. With IgG (-) and IgM (-). Based on gender, 15 people (73.8%) were male and 45 people (26.3%) were female. It is known that the value of X2 calculated from the results of the chi-square statistic = 45.3> > X2 table =5,954 with a value r = 0,000 (< 0,05). Conclusion : Results: Based on the research results, IgG and IgM in dengue fever patients were mostly found based on the results of serological analysis of IgG (+) and IgM (-) with secondary dengue fever, and were found in other patients. Dengue fever sufferers are more often men than women.Keywords: DHF, IgG Level Analysis, IgM Level Analysis
HUBUNGAN PERILAKU MEROKOK DENGAN KEJADIAN HIPERTENSI DI RW 02 KELURAHAN SUMBER HARTA UPT PUSKESMAS SUMBER HARTA LUBUK LINGGAU Santoso, Santoso; Dewi, Devi Cynthia; Andrianti, Septi
Mitra Raflesia (Journal of Health Science) Vol 14, No 1 (2022)
Publisher : LPPM STIKES BHAKTI HUSADA BENGKULU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51712/mitraraflesia.v14i1.192

Abstract

ABSTRAK Latar Belakang : Hipertensi merupakan salah satu penyebab kematian dini pada masyarakat di dunia dan semakin lama, permasalahan tersebut semakin meningkat. Salah satu faktor risiko hipertensi adalah kebiasaan merokok. Masalah penelitian adalah masih banyaknya kejadian hipertensi di Rw 02 Kelurahan Sumber Harta UPT Puskesmas Sumber Harta Tahun 2022. Tujuan penelitian adalah diketahui Hubungan Perilaku Merokok Dengan kejadian Hipertensi di Rw 02 Kelurahan Sumber Harta UPT Puskesmas Sumber Harta Tahun 2022.Metode : Jenis penelitian yang digunakan adalah Cross sectional. Populasi sebanyak 257 orang dan sampel penelitian sebanyak 72 orang. Jenis data yang digunakan dalam penelitian adalah menggunakan data primer dan sekunder. Analisis data univariat dan bivariat dengan metode statistik chi square pada taraf signifikansi 0,05.Hasil analisis univariat didapatkan terdapat sebanyak 53 orang (73,6%) pernah merokok dan terdapat sebanyak 47 orang (65,3%) dengan hipertensi. Ada hubungan yang bermakna antara kebiasan merokok dengan kejadian hipertensi di Rw 02 Kelurahan Sumber Harta UPT Puskesmas Sumber Harta Lubuklinggau dengan nilai p = 0,028.Simpulan : Kepala UPT Puskesmas Sumber Harta Lubuklinggau agar mempertimbangkan untuk membentuk klinik berhenti merokok di UPT Puskesmas Sumber Harta Lubuklinggau sehingga pasien yang memiliki kebiasaan merokok terfasilitasi untuk berhenti merokok dan mengurangi kejadian hipertensi.Kata Kunci : Perilaku Merokok, Hipertensi.  ABSTRACT Baground : Hypertension is one of the causes of premature death in people in the world and the longer the problem is increasing. One of the risk factors for hypertension is smoking. The research problem is that there are still many occurrences of hypertension in Rw 02 Sumber Harta Village UPT Sumber Harta Health Center in 2022. The purpose of this study is to find out the relationship between smoking behavior and the incidence of hypertension in Rw 02 Sumber Harta Village UPT Sumber Harta Health Center in 2022.Method : The type of research used is cross sectional. The population is 257 people and the research sample is 72 people. The type of data used in this research is using primary and secondary data. Analysis of univariate and bivariate data with the chi square statistical method at a significance level of 0.05.Result :The results of the univariate analysis showed that there were 53 people (73.6%) who had smoked and there were 47 people (65.3%) with hypertension. There is a significant relationship between smoking habits and the incidence of hypertension in Rw 02 Sumber Harta Village UPT Sumber Harta Health Center Lubuklinggau with p = 0.028.Conclusion : The head of the UPT Puskesmas Sumber Harta Lubuklinggau should consider establishing a smoking cessation clinic at the UPT Puskesmas Sumber Harta Lubuklinggau so that patients who have smoking habits are facilitated to stop smoking and reduce the incidence of hypertension.Keywords: Smoking Behavior, Hypertension.
KORELASI ANTARA STATUS IMUNITAS DENGAN KEJADIAN INSOMNIA PADA LANSIA DI PANTI JOMPO TRESNA WERDHA KOTA BENGKULU Dewi, Devi Cynthia; Nunu Harison; Feny Marlena
Mitra Raflesia (Journal of Health Science) Vol. 17 No. 1 (2025)
Publisher : LPPM STIKES BHAKTI HUSADA BENGKULU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51712/7z30yq93

Abstract

ABSTRAK Pendahuluan: Sistem kekebalan pada tubuh berperan dalam perbaikan DNA manusia, pencegahan infeksi yang dikarenakan oleh virus, bakteri maupun jamur serta mikroorganisme lainnya, dan sistem imun juga dapat menghasilkan antibodi (immunoglobulin). Apabila kebutuhan tidur pada lansia tidak tercukupi akan berdampak negatif terhadap kesehatannya seperti lansia akan lebih emosional dan penurunan dari fungsi kekebalan tubuh. Lansia dengan kualitas tidur yang buruk menyebabkan terganggunya aktivitas keesokan harinya, sulit mengendalikan emosionalnya dan akan kurang semangat dalam menjalankan aktivitas sehari-harinya. Lansia yang mengalami insomnia dapat meningkatkan risiko-risiko kesehatannya, fungsi sistem imun akan rusak. Tujuan : Penelitian ini dilakukan untuk mengetahui korelasi status Imunitas dengan kejadian Insomnia di Panti Jompo Tresna Werdha Kota Bengkulu. Metode Penelitian : Penelitian dilakukan dengan rancang bangun cross sectional. Subyek penelitian diambil dari populasi dengan cara simple random sampling. Sampel penelitian berjumlah 74 lansia dengan teknik pengambilan sampel purposive sampling. Data penelitian diambil dengan cara wawancara menggunakan kuisioner KSPBJ-IRS dan ISQ. Hasil penelitian dianalisis dengan aplikasi statistik. Skala data berupa nominal dan dilakukan analisis meggunakan uji Chi Square. Hasil : Hasil penelitian menunjukan bahwa lansia dengan status imunitas yang kurang baik 73,5% mengalami insomnia dan 26,5% yang tidak mengalami insomnia. Lansia dengan dengan status imun baik 31,5% tidak insomnia dan 68,5% mengalami insomnia. Hasil uji menggunakan uji analisis Chi Square untuk mengetahui korelasi status imunitas dengan kejadian insomnia didapatkan nilai 0,01 (p<0,05). Berdasarkan hasil penelitian menunjukkan adanya hubungan yang bermakna antara status imunitas dengan kejadian insomnia pada lansia di Panti Jompo Tresna Werdha Kota Bengkulu. Kesimpulan : Dari penelitian ini menunjukkan bahwa terdapat korelasi yang bermakna antara status imunitas dengan kejadian Insomnia pada lansia di Panti Jompo Tresna Werdha Kota Bengkulu. Saran : Penelitian selanjutnya dapat dikembangkan variabelnya, contohnya hubungan insomnia dengan sel penanda imun tubuh dan kadar sitokin inflamasi. Kata Kunci: Status Imunitas, Kejadian Insomnia, Lanjut Usia   ABSTRACT Introduction: The immune system in the body plays a role in repairing human DNA, preventing infections caused by viruses, bacteria or fungi and other microorganisms, and the immune system can also produce antibodies (immunoglobulins). If the need for sleep in the elderly is not met, it will have a negative impact on their health, such as the elderly will be more emotional and a decrease in immune function. Elderly people with poor sleep quality cause disruption of activities the next day, difficulty controlling their emotions and will be less enthusiastic in carrying out their daily activities. Elderly people who experience insomnia can increase their health risks, the function of the immune system will be damaged. Purpose: This study was conducted to determine the correlation between Immunity status and the incidence of Insomnia at the Tresna Wherdha Nursing Home in Bengkulu City. Research Method: The study was conducted with a cross-sectional design. The research subjects were taken from the population by simple random sampling. The research sample was 74 elderly people with a purposive sampling technique. Research data were taken by interview using the KSPBJ-IRS and ISQ questionnaires. The results of the study were analyzed using statistical applications. The data scale is nominal and the analysis was carried out using the Chi Square test. Results: The results of the study showed that 73.5% of elderly people with poor immune status experienced insomnia and 26.5% did not experience insomnia. 31.5% of elderly people with good immune status did not experience insomnia and 68.5% experienced insomnia. The results of the test using the Chi Square analysis test to determine the relationship between insomnia and immune status obtained a value of 0.01 (p <0.05). Based on the results of the study, it showed a significant relationship between insomnia and immune status in the elderly at the Tresna Wherdha Nursing Home, Bengkulu City. Conclusion: This study shows that there is a significant correlation between immune status and the incidence of insomnia in the elderly at the Tresna Wherdha Nursing Home, Bengkulu City. Suggestion: Further research can develop variables, for example the relationship between insomnia and immune marker cells and inflammatory cytokine levels Keywords: Immune Status, Insomnia Incidence, Elderly
Co-Authors Agus Riyanto Andrianti, Septi Feny Marlena Horison, Nunu Kaharuddin, Riski Muhammad Akbar Marlena, Feni Miranda, Tenike Gita Ningsih, Siska Ayu Novega, Miki Kurnia Fitrizah Novitasari, Deltari Nunu Harison Nur Asmah, Nur Podesta, Ardiana Puspita, Tari Rozy, Veby Fransisca S.Pd. M Kes I Ketut Sudiana . SANTOSO SANTOSO Shinta Shinta