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Journal : World Nutrition Journal

Correlation of calorie intake with 24-hour urinary urea nitrogen level changes in critically ill patients at RSUI Depok, Indonesia Githa Putri Puspita Sari; Witjaksono, Fiastuti; Sutanto, Krisadelfa; Singal, Anna Maurina
World Nutrition Journal Vol. 8 No. S1 (2024): Selected conference proceedings of the Nutri Symposium 2024
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.S1.0041

Abstract

Calorie together with protein intake has been proven to be important factors that play a role in critically ill patients. Hypermetabolism in the early acute phase increases energy expenditure and calorie requirement. Insufficient calorie intake will increase protein degradation for gluconeogenesis, which can be assessed by the level of 24-hour urinary urea nitrogen (UUN). Adequate daily calorie intake is expected to improve the UUN level in patients. This study aims to investigates the correlation of calorie intake with UUN level changes in critically ill patients.
Correlation of energy and protein intake with nitrogen balance changes in late acute phase critically ill patients Githa Putri Puspita Sari; Witjaksono, Fiastuti; Sutanto, Krisadelfa; Singal, Anna Maurina
World Nutrition Journal Vol. 8 No. i2 (2025): Volume 08 Issue 2, February 2025
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.i2.0007

Abstract

Background: The hypercatabolic process due to metabolic stress in critically ill patients, especially in the acute phase, is very high, causing protein degradation. Inadequate intake and high protein losses will result in a negative nitrogen balance. Objective: To analyze the correlation of energy and protein intake in the late acute phase with nitrogen balance changes. Methods: This study’s method was cross−sectional with consecutive sampling, conducted in the ICU of the university of Indonesia hospital. Energy and protein intake were assessed for 7 days. On days 3 and 7 of treatment, 24−hour urine urea nitrogen levels and nitrogen balance (NB) were assessed. Twenty three subjects participants in this study. Results: There was a positive correlation between energy and protein intake with NB on day 3 (r=0.5, p=0.01 ;r=0.6, p=0.003). The mean nitrogen balance changes was positive, namely 3.8 g. There was a significant correlation between energy and protein intake with NB changes (p>0.01) Conclusion: Energy and protein intake were positively correlated with nitrogen balance in the early acute phase. The results show that the administration of energy and protein starting at low intake in the early acute phase and gradually reaching the target intake during the late acute phase leads to an improvement in nitrogen balance.
Leucine-included liquid diet as medical nutrition therapy improved handgrip strength and mid-upper circumference in clinically malnourished pulmonary tuberculosis patient with high neutrophil lymphocyte ratio: A case report from Universitas Indonesia hospital Singal, Anna Maurina; Afifa, Nadhira Nuraini; Wardhani, Wahyu Ika; Baskoro, Hario
World Nutrition Journal Vol. 8 No. i2 (2025): Volume 08 Issue 2, February 2025
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.i2.0005

Abstract

Background and objectives: Muscle weakness delays clinical improvement in pulmonary tuberculosis patients. Higher neutrophil lymphocyte ratio, low handgrip strength, mid-upper arm circumference indicates bad clinical outcome. Weight loss must be managed from the start of treatment. Good muscle condition has benefits to the recovery rate. Leucine provides benefits in increasing the synthesis of muscle mass so as the clinical conditions. Unfortunately, leucine has not been the routine part of medical nutrition therapy in tuberculosis patients. Methods: This is a case report of a female patient with body weight 42 kg and height 150 cm, admitted to Universitas Indonesia Hospital, with lung tuberculosis. Leucine given, started from 1.95 g/day to the maximum amount of 7,34 g/day through the hospital tailored-made liquid food. There was an improvement of clinical signs and symptoms during 14 days of hospitalization. Mid-upper arm circumferences at day 1, 8, and 15 were 21.1, 21.4, and 12.9 21.9 cm in a row. The right and left handgrip strength at day 1, 8, and 15 were 9.7 kg and 8.1 kg, 10.9 kg and 8.9 kg, 15.1 kg and 13.4 kg, respectively. While the neutrophil lymphocyte ratio at day 0, 6, and 9 were increasing, at 6.89, 6.89, and 13.8, in a row. Conclusions: Leucine 1.95–7.34 g/day, in tailored-made liquid food, as part of tuberculosis management therapy, though the NLR 13.8, can improve the mid-upper arm circumference, handgrip strength, clinical signs and symptoms in 14 days of hospitalization.
Relationship between age and vas appetite score among patients with post-tuberculosis lung disease at Persahabatan National Respiratory Referral Hospital, Jakarta Mahardika, Linda; Nurwidya, Fariz; Singal, Anna Maurina
World Nutrition Journal Vol. 9 No. S1 (2025): Vol. 9 No. S1 (2025): Selected conference proceedings of the Nutri Symposium 2
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V09.S1.0022

Abstract

Background: Post-tuberculosis lung disease (PTLD) is a form of progressive lung tissue damage following tuberculosis (TB) infection. In addition to clinical symptoms, patients with PTLD often experience nutritional problems. Appetite plays a crucial role in determining adequate nutrient intake, which can affect nutritional status, the recovery process, and overall quality of life. One factor that may influence appetite is age. Although age is known to affect appetite, the relationship between the two has not been studied, particularly in patients with PTLD at Persahabatan Hospital, National Respiratory Centre.