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All Journal Jurnal Ilmu Dasar Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Biology, Medicine, & Natural Product Chemistry Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) Jurnal Abdi Insani Journal of Tropical Ethnobiology Jurnal Mitra Kesehatan International Islamic Medical Journal Bioscientist : Jurnal Ilmiah Biologi Rumphius Pattimura Biological Journal Proceeding of International Conference on Biology Education, Natural Science, and Technology
Nathalia, Dede Dwi
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Antibacterial Bioactivity Test of Bilimbi Fruit Ethanol Extract (Averrhoa bilimbi Linn). Against Propionibacterium acnes, Staphylococcus epidermidis and Staphylococcus aureus Anindita, Reza; Nathalia, Dede Dwi; Perwitasari, Melania; Putri, Intan Kurnia; Beandrade, Maya Uzia; Harahap, Nofria Rizki Amalia
Biology, Medicine, & Natural Product Chemistry Vol 13, No 1 (2024)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2024.131.173-182

Abstract

One of the causes of acnes is the bacteria Propionibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus. An alternative solution to this problem is to develop natural medicines from plants, one of which is the star fruit (Averrhoa bilimbi Linn). The purpose of this study was to test the bioactivity of star fruit against the growth of P. acnes, S. epidermidis, and S. aureus. This research method used an experimental research design with the treatment of A. bilimbi fruit ethanol extract concentrations of 50%, 60%, 70%, 80%, and 90%, chloramphenicol antibiotics as control (+), and sterile distilled water as control (-). All treatments were given to P. acnes, S. epidermidis, and S. aureus bacteria using the Kirby Baeur (disc diffusion) method. The results of this study were the effectiveness of the bioactivity compound of the ethanolic extract of A. bilimbi fruit seen on P. acnes and S. epidermidis bacteria with concentrations of 70%, 80%, and 90%. Thus, it can be concluded that A. bilimbi fruit has the potential to be developed as a natural medicine for acne caused by P. acnes and S. epidermidis.
Monitoring Pediculosis Capitis in Students At Al-Muhajirin Islamic Boarding School, Cikarang Pusat, West Java, Indonesia Anindita, Reza; Wahyu, Ega Nuraini; Perwitasari, Melania; Nathalia, Dede Dwi; Beandrade, Maya Uzia; Harahap, Nofria Rizki Amalia
Jurnal Medis Islam Internasional Vol 5 No 2 (2024)
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i2.5783

Abstract

Introduction : Pediculosis capitis is a scalp hair disorder caused by an infestation of the lice of Pediculus humanus capitis. The spread of this disease is dominant in Islamic boarding school students. This disease besides causing itching and lesions on the scalp also causes loss of concentration and enjoyment of learning in children. The objective of this study was to determine the percentage of female students infested with P. humanus capitis. Methods : The design of this research is cross-sectional. The sample for this study was 41 female students of grade 7 at AL-Muhajirin Islamic Boarding School, Central Cikarang, West Java. Examination of  P. humanus capitis on all female students was carried out using the serit method. The P. humanus capitis lice found were then collected and preserved preparations were made for microscopic morphological identification. Results : The results of this study showed that from 41 samples, 36 (87.8%) students were found to be positive for P. humanus capitis. Conclusions : The conclusion from this study is that the percentage of pediculosis capitis in female students is high, so it is necessary to take countermeasures in the form of head lice medication and education about personal hygiene for class 7 female students at Al-Muhajirin Islamic Boarding School, Central Cikarang, West Java
Anti-Bacterial Activity of Etanolic Extract and Essential Oil of Basil (Ocimum sanctum) on Growth Staphylococcus aureus Salmonella thypii and Eschericia coli Perwitasari, Melania; Anindita, Reza; Beandrade, Maya Uzia; Nathalia, Dede Dwi; Hasmar, Wahyu Nuraini; Putri, Intan Kurnia
Jurnal ILMU DASAR Vol 24 No 2 (2023)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jid.v24i2.31367

Abstract

Antimicrobial resistance is one of the biggest health problems. Indonesia is a country with a positive high number of E. coli (71%) Extended Spectrum Beta Lactamase (ESBL) in the Asia Pacific. Many studies report that essential oils and extracts from several species of Ocimum have antimicrobial activity against gram-positive and negative bacteria. Antibacterial activity is related to active compounds contained in plants that are also affected by the place of growth, harvesting and post-harvesting. Research related to the activity of basil (Ocimum sanctum) that already exists does not provide complete and comprehensive data related to where to grow, harvest and post-harvest basil leaves. Basil leaves that have been set parameters for growth, harvest and post-harvest processes are extracted using maceration method with 70% etanol solvent and distilled to obtain essential oils (EO). Etanolic extract (EE) and EO were tested for their activity against Escherichia coli, Staphylococcus aureus and Salmonella thypii bacteria. The results showed that the basil leaves obtained from Margahayu sub-district, East Bekasi, had a dry simplicia yield of 12.8% ± 1.5, yield of EE 16.9% ± 1.6, EO content of 0.56%. The etanolic extract of basil leaves contains alkaloids, saponins, tannins, phenolics, flavonoids, glycosides, triterpenoids and steroids. The conclusion from the results of this study is the etanol extract and essential oils of basil leaves can inhibit the growth of bacteria, both basile leaves. The inhibition zone diameter is higher in gram positive bacteria (S. aureus) than gram negative bacteria (S. thypii and E. coli).
Community Knowledge about Medicinal Plants in Samudra Jaya and Pahlawan Setia Villages, North Bekasi Anindita, Reza; Haediningrum, Syahla; Beandrade, Maya Uzia; Putri, Intan Kurnia; Nathalia, Dede Dwi; Perwitasari, Melania; Harahap, Nofria Rizki Amalia; Rahmadi, Chandra
Journal of Tropical Ethnobiology Vol. 7 No. 1 (2024): January 2024
Publisher : The Ethnobiological Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The purpose of this study was to describe the knowledge and use of medicinal plants by the people of Samudra Jaya and Pahlawan Setia Villages, Tarumajaya Sub-district, North Bekasi. The research design is an exploratory survey and observation. The sample numbered 119 people, consisting of 69 people representing Pahlawan Setia Village and 50 people representing Samudra Jaya Village. The sampling technique used purposive random sampling. Variables in this study include the value of community knowledge about medicinal plants, the value of community knowledge about the use of medicinal plants, the organs of plants that are often used, the percentage of how to use medicinal plants, and the families and species of plants used as medicine. Data analysis was carried out descriptively. The results showed that the value of community knowledge about medicinal plants was 354 (classified as good), the value of community knowledge regarding the use of medicinal plants was 300.4 (classified as good), the organs of plants that were often used as medicine were leaves (95%), the percentage of how to use medicinal plants are more dominant by boiling (91%), there are 19 families with 22 species of plants used as medicine. The family includes Zingiberaceae, Polygonaceae, Liliaceae, Acanthaceae, Oxalidaceae, Talinaceae, Crassulaceae, Rubiaceae, Lamiaceae, Piperaceae, Basellaceae, Euphorbiaceae, Solanaceae, Caricaceae, Menispermaceae, Asparagaceae, Zingiberaceae, Myrtaceae, Rutaceae, Leguminosae, and Moraceae, with plant species: kunyit (Curcuma domestica), jambu biji (Psidium guajava), sirih hijau (Piper betle), mengkudu (Morinda citrifolia), lidah buaya (Aloe vera), brotowali (Tinospora crispa), sambiloto (Andrographis paniculata), saga (Abrus precatorius), jahe (Zingiber officinale), belimbing wuluh (Averrhoa bilimbi), cocor bebek (Kalanchoe pinnata), ciplukan (Physalis peruviana), jeruk nipis (Citrus aurantiifolia), jarak pagar (Jatropa curcas), kumis kucing (Orthosiphon aristatus), gondola (Basella rubhalin), pepaya (Carica papaya), ginseng jawa (Talinum paniculatum), telang (Clitoria ternatea), getih-getihan (Rivina humilis), tin (Ficus carica), and suji (Dracaena angustifolia). The study concludes that the results of survey scores regarding the knowledge and use of medicinal plants by the people of Samudra Jaya and Pahlawan Setia Villages are classified as good. The species of medicinal plants that are most widely used are the Zingiberaceae family, with local names of plant species, namely jahe and kunyit. Both plants are used by boiling to relieve menstrual pain and treat bloating and colds.
ACCURACY OF THE USE OF ANTITUBERCULOSIS DRUGS IN PATIENTS WITH PULMONARY TUBERCULOSIS COMORBID WITH TYPE 2 DIABETES MELITUS IN HOSPITAL X BEKASI CITY FOR THE PERIOD 2019-2022: ACCURACY OF THE USE OF ANTITUBERCULOSIS DRUGS IN PATIENTS WITH PULMONARY TUBERCULOSIS COMORBID WITH TYPE 2 DIABETES MELITUS IN HOSPITAL X BEKASI CITY FOR THE PERIOD 2019-2022 rachmita arianti, Anisa; Dzakiya, Meisya Putri; Harahap, Nofria Rizki Amalia; Nathalia, Dede Dwi
Jurnal Mitra Kesehatan Vol. 7 No. 1 (2024): Jurnal Mitra Kesehatan
Publisher : STIKes Mitra Keluarga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47522/jmk.v7i1.373

Abstract

Introduction: Pulmonary tuberculosis is a chronic infection caused by the bacterium Mycobacterium tuberculosis. The disease can lead to severe complications, including diabetes, which increases the risk of death. In addition, the prevalence of TB-DM in Indonesia reaches 14.8%. Objective: This study was to evaluate the use of antituberculosis drugs in patients with pulmonary TB comorbid with diabetes mellitus using the right indication, right dose, and right drug indicators. Methods: The research design used was observational with a retrospective approach. This study used independent variables including age, gender, treatment profile, stage of treatment, correct drug, correct dose and correct indication. The sampling technique used was consecutive sampling. The sample of this study consisted of 62 outpatients who were analyzeddescriptively quantitatively using Microsoft Excel. Results: This study shows that the number of male (65%) and female (35%) patients with the majority age 46-55 years (45%). Lung TB drug use therapy is dominant OAT Kombipak (69.4%) and KDT (30.6%). Evaluation of drug use showed the level of indication accuracy of 100%, the right dose of 83.9%, and the right drug of 93.5%. Conclusion: Based on compliance with the "National Guidelines for TB Control" issued by the Ministry of Health of the Republic of Indonesia in 2016, the treatment provided to outpatient TB patients with DM comorbidity at Hospital X in Bekasi Cityfrom 2019 to 2022 showed a 100% accuracy rate for indications (62 patients), 83.9% accuracy rate for dosages (52 patients), and 93.5% accuracy rate for drug selection (58 patients).
Botany, Pharmacognosy, and Phytochemical Study of Gymnanthemum amygdalina (Delile) Sch.Bip. Leaves from Bandung, West Java, Indonesia Anindita, Reza; Tahapary, Manuela Esterlita; Nathalia, Dede Dwi; Putri, Intan Kurnia; Beandrade, Maya Uzia
RUMPHIUS Vol 7 No 2 (2025): RUMPHIUS Pattimura Biological Journal
Publisher : Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/rumphiusv7i2p138-147

Abstract

Gymnanthemum amygdalina (Delile) Sch.Bip. possesses antioxidant, antibacterial, anticholesterol, anticancer, and antidiabetic properties. This study aimed to determine the morphology of leaves, stems, flowers, and roots, as well as the microscopic powder characteristics, phytochemical profile, and Thin Layer Chromatography (TLC) pattern of G. amygdalina leaves. The samples were collected from Bandung City, West Java, Indonesia. Methods included morphological examination, microscopic powder analysis, phytochemical screening, and TLC. The morphological characterization of G. amygdalina showed that the leaves measured 10–22 cm in length and 2–8 cm in width, with an oblong shape, acuminate tips, acute bases, pinnate venation, serrated margins, rough surfaces, woody stems, and a taproot system. Microscopic examination revealed fragments of trichomes. Phytochemical screening indicated the presence of alkaloids, flavonoids, saponins, tannins, and terpenoids/steroids. TLC analysis showed five red spots with an average Rf value ranging from 0.06 to 0.58. In conclusion, the morphological characteristics of G. amygdalina leaves were identified, microscopic analysis revealed trichome fragments, and phytochemical screening confirmed the presence of secondary metabolites. TLC analysis yielded Rf values between 0.06 and 0.58.
PENGARUH PELAYANAN KESEHATAN TERHADAP KEPUASAN PASIEN PERBANDINGAN ANTARA SISTEM TMH DENGAN SISTEM MANDIRI INHEALTH Nathalia, Dede Dwi; Hasan, Delina; Aritonang, MGS
Media Farmasi: Jurnal Ilmu Farmasi Vol. 14 No. 1: Maret 2017
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v14i1.9828

Abstract

Penelitian ini bertujuan untuk membandingkan seberapa besar pengaruh pelayanan kesehatan terhadap kepuasan pasien antara sistem TMH dengan sistem Mandiri Inhealth. Dari data tahun 2009 sampai dengan 2015 terjadi peningkatan biaya kesehatan PT.TMH dan premi serta pelayanan kesehatan berupa manfaat asuransi (benefit) dan jenis pelayanan kesehatan yang diperoleh pasien PT. TMH tidak bisa tercover seluruhnya. Metode yang digunakan adalah metode deskriptif kuantitatif dengan survei analitik. Pengukuran pelayanan kesehatan (variabel X1 dan X2) menggunakan konsep servqual (dimensi reliability, reponsiveness, assurance, empathy dan tangibles) serta pengukuran kepuasan pasien (variabel Y) dengan dimensi perceive performance dan expectation. Populasi dalam penelitian ini adalah kelompok pasien karyawan aktif dan pensiunan karyawan PT.TMH yang didata pada bulan Juli 2015 sampai dengan November 2015 dengan total jumlah 14.048. Metode pengambilan sampel dengan metode proportionate random sampling maka jumlah sampel yang diambil adalah 100 responden. Subyek penelitian ini adalah karyawan PT.TMH dan pensiunan PT. TMH yang tinggalnya di sekitar Jabodetabek. Dari hasil pengujian hipotesis diperoleh hasil uji t independen dengan nilai p = 0,000 < 0,05 untuk skor pelayanan kesehatan dan skor kepuasan pasien. Berdasarkan hasil pengujian hipotesis dapat disimpulkan bahwa pelayanan kesehatan dengan sistem PT. TMH dan pelayanan kesehatan dengan sistem Mandiri Inhealth mempunyai pengaruh positif terhadap kepuasan pasien, tetapi ada perbedaan yang signifikan pada kedua sistem tersebut dimana pelayanan kesehatan sistem PT.TMH lebih baik dan lebih memuaskan daripada sistem Mandiri Inhealth.
Uji Nanoemulsi Ecoenzym Terhadap Bakteri Staphylococcus aureus anindita, Reza; Nathalia, Dede Dwi; Beandrade, Maya Uzia; Putri, Intan Kurnia; Sari, Afrinia Eka; Setyodewi, Elisabeth
Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) Vol 9 No 2 (2024): January 2024
Publisher : Fakultas Matematika & Ilmu Pengetahuan Alam - Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/e-jbst.v9i2.553

Abstract

The discovery of eco enzyme as a fermented liquid from organic vegetable and fruit waste has been used as an organic plant fertilizer, disinfectant, hand sanitizer, antiseptic soap, and domestic waste degradation agent. However, trials of eco enzymes as raw materials for health preparations have not yet been carried out. Seeing this, trial research is needed on the use of ecoenzyme nanoemulsion against Staphylococcus aureus bacteria. This research aims to determine the antibacterial ability of ecoenzyme nanoemulsion against S. aureus bacteria. The design of this research is experimental. The samples used were ecoenzyme nanoemulsions with Formula 1 (F1) 20%, Formula 2 (F2) 25%, and Formula 3 (F3) 30%. This research includes making ecoenzyme, making ecoenzyme nanoemulsion, testing ecoenzyme nanoparticles, and testing ecoenezyme nanoemulsion against S. aureus bacteria using the Kirby-Baeur method. The results showed that the sizes of ecoenzyme nanoparticles in F1 20%, F2 25%, and F3 30% were 38.9 nm, 65.07 nm, and 146.2 nm, respectively. The results of the antibacterial ability test of nanoemulsion eco enzyme F1 20%, F2 25%, and F3 30% against S. aureus produced an inhibitory zone 4.3 mm (resistant), 4.3 mm (resistant), and 6.7 mm (resistant). This research concludes that the eco enzyme nanoemulsion is not effective in inhibiting the growth of S. aureus bacteria.
Digitalisasi Preparat Mikroskopis Plasmodium falciparum dan Plasmodium vivax Sebagai Media Pembelajaran Protozoologi Anindita, Reza; Nathalia, Dede Dwi; Rahmadi, Chandra
Bioscientist : Jurnal Ilmiah Biologi Vol. 12 No. 2 (2024): December
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v12i2.13803

Abstract

One of the competencies of health students in the health protozoology course is being able to identify the microscopic morphology of Plasmodium sp. However, the identification of Plasmodium sp. is still widely done using conventional ATLAS. Therefore, innovation is needed using digital ATLAS. The purpose of this study was to digitize microscopic images of Plasmodium vivax and falciparum as a learning medium for protozoology courses. This type of research is quantitative descriptive. The sources of digital data in this study were Plasmodium falciparum trophozoite and gametocyte phase preparations and Plasmodium vivax amoeboid phase. This research method includes documentation, editing, validation, description, inventory, and evaluation. The results of this study are the number of images that were successfully digitized is 158 images consisting of Plasmodium falciparum ring phase as many as 58, gametocyte phase as many as 19, and P. vivax as many as 81 images with quality including the sufficient category, the percentage of digital ATLAS usage is 73.6 while conventional ATLAS is 47.8. The conclusion of this study is that the digitalization of microscopic images of Plasmodium vivax and falciparum can be developed into an Android-based application.
Monitoring The Correlation of Climatics to The Airborne Bacteria at The Manggarai Station, South Jakarta, Indonesia Anindita, Reza; Rahmawati, Auliya; Inggraini, Maulin; Perwitasari, Melania; Nathalia, Dede Dwi; Beandrade, Maya Uzia; Putri, Intan Kurnia
Proceeding of International Conference on Biology Education, Natural Science, and Technology 2023: Proceeding of International Conference on Biology Education, Natural Science, and Technology
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The highest of microorganisms suspended in the air were bacteria with a percentage of 80.8%. If the intensity of bacterial exposure occurs in large quantities, it will accumulate in the respiratory tract which has the potential to trigger allergic reactions and respiratory infections. Given the problems and impacts caused by air microorganisms on public health, it is necessary to monitor the distribution of air bacteria. The purpose of this study was to determine the relationship between temperature and humidity with the number of bacteria in the Manggarai station area. Type of research is correlation. The sampling location is Manggarai Station, East Jakarta, Indonesia. The 10 sampling points in this study include the station hall, motorbike parking, prayer rooms, train platform 1-2, train platform 2-3, train platform 3-4, and train platform 5, toilet, and underpass. The results of this study included the highest number of bacteria found in the station hall 331 colonies, the highest percentage of bacterial morphology is monobacilli was 78%, the distribution of gram positive was more than gram negative with spore bacteria being more dominant than non spore. The correlation coefficient between temperature and number of bacterial colonies (0.134) and humidity with number of bacterial colonies (0.380) showed weak positive correlation, while the correlation coefficient for light intensity with the number of bacterial colonies -0.140 (very weak negative).
Co-Authors Afrinia Ekasari Aritonang, MGS Auliya Rahmawati, Auliya Beandrade, Maya Uzia Dzakiya, Meisya Putri Haediningrum, Syahla Harahap, Nofria Rizki Amalia Hasan, Delina Hasmar, Wahyu Nuraini Inggraini, Maulin Melania Perwitasari, Melania Putri, Intan Kurnia rachmita arianti, Anisa Rahmadi, Chandra Setyodewi, Elisabeth Tahapary, Manuela Esterlita Wahyu, Ega Nuraini