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All Journal Prima JODS Buletin Kedokteran dan Kesehatan Prima
Adriana, Shirley
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Uji organoleptik produk obat kumur minyak atsiri buah kapulaga Savant, Andika Marcho; Erawati, Suci; Adriana, Shirley; Molek, Molek; Sinamo, Sopan; Susanto, Chandra; Nababan, Idamawati
Prima Journal of Oral and Dental Sciences Vol. 6 No. 2 (2023): Edisi Oktober
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/primajods.v6i2.4756

Abstract

Penelitian ini bertujuan untuk mengetahui analisis uji organoleptik produk obat kumur minyak atsiri buah kapulaga pada pasien di Halitosis Care Center RS Siti Hajar Medan. Jenis penelitian adalah survei dengan desain cross sectional denganxpopulasi pasien halitosis yang berobat di Halitosis Care Center RS Siti Hajar Medan. Besar sampel dihitung menggunakan rumus estimasi proporsi dan diperoleh sampel sebanyak 35 orang. Pengujian organoleptik dengan cara menyebarkan kuesioner kepada sampel melalui Google form dengan memberikan penilaian terhadap produk obat kumur minyak atsiri buah kapulaga ditinjau dari rasa, aroma, warna, dan bentuk. Data dianalsiis secara deksriptif. Berdasarkan hasil penelitian, mayoritas responden menyebutkan bahwa rasa dari obat kumur adalah enak (40%), dan segar (51,4%), sangat beraroma (51,4%) dengan aroma yang wangi dan segar (45,7%), warna yang sangat menarik (45,7%), dan bentuk dari produk membuat responden sangat tertarik untuk dibeli (54,3%). Produk obat kumur minyak atsiri buah kapulaga telah memiliki kualitas yang sangat baik.
Comparison of the effectiveness of robusta coffee bean extract and arabica coffee bean extract on the growth of Candida albicans Adriana, Shirley; Pinem, Pinta Malem; Watri, Desi
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6667

Abstract

Oral thrush, a fungal infection often associated with inadequate oral hygiene, necessitates treatment with antimicrobial agents. Extracts from Coffea canephora (Robusta) and Coffea arabica L. (Arabica) coffee beans contain bioactive compounds that demonstrate inhibitory activity against Candida albicans. This study investigated the comparative inhibitory efficacy of Robusta and Arabica coffee bean extracts on Candida albicans growth. A randomised, post-test only control group design was employed in this experimental laboratory study. Twelve treatment groups were established, and the disc diffusion method was used to assess antibacterial activity. Inhibition diameters were measured using a vernier caliper. Statistical analysis was performed using the Kruskal-Wallis and Mann-Whitney tests. The mean inhibition diameters for Robusta coffee bean extract (Coffea canephora) were as follows: 9.28 ± 2.585 mm at 12.5% concentration, 12.35 ± 0.050 mm at 25%, 14.55 ± 0.050 mm at 50%, 16.50 ± 0.477 mm at 75%, and 18.55 ± 0.477 mm at 100%. For Arabica coffee bean extract (Coffea arabica L.), the mean inhibition diameters against Candida albicans were 8.10 ± 1.117 mm at 25% concentration, 10.91 ± 1.188 mm at 50%, 15.61 ± 2.115 mm at 75%, and 16.71 ± 1.980 mm at 100%. The positive control exhibited a mean inhibition diameter of 15.85 ± 0.180 mm. No inhibition was observed for Arabica coffee bean extract at 12.5% concentration or the negative control. The results indicate that Robusta coffee bean extract demonstrated a significantly greater inhibitory effect on Candida albicans growth compared to Arabica coffee bean extract. Liquid chromatography-mass spectrometry (LC-MS) analysis of both Robusta and Arabica coffee bean extracts revealed the presence of caffeine and chlorogenic acid, which likely contribute to their observed inhibitory activity.
Co-Authors Erawati, Suci Molek, Molek nababan, idamawati Pinem, Pinta Malem RR. Ella Evrita Hestiandari Savant, Andika Marcho Sinamo, Sopan Watri, Desi