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All Journal International Islamic Medical Journal Prosiding Seminar Nasional dan Call Paper STIE Widya Wiwaha
Noviana, Dian
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Religion Humanities Economics, Econometrics & Finance Health Professions Medicine & Pharmacology Public Health

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The Effect of Honey Administration on The Histopathology of The Duodenum of Wistar Rats as a Inhibition of The Toxic Effects of Borax (Sodium tetraborate) Noviana, Dian; Syarifah, Mustika Chasanatusy; Gumilang, Retna; Bintarti, Tri Wahyuni
Jurnal Medis Islam Internasional Vol 4 No 2 (2023): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i2.4445

Abstract

Background: Borax can result in oxidative stress and cause the onset of gastrointestinal ulcerations that will dampen the duodenal villi to become shorter and can even disappear. Cell damage due to oxidative stress can be prevented by administering antioxidants. Antioxidants will inhibit the onset of chain reactions in the formation of free radicals by complementing the existing electron deficiency. Honey is one of the natural ingredients that is rich in antioxidants and part of thibbun Nabawi as one of the inhibitors of the toxic effects of borax. Objective : The purpose of this study is to to analyze the effect of honey administration on the histopathological description of submucosa and epithelial mucosa of duodenal wistar rats as an inhibitor of the toxic effects of borax (Sodium tetraborate). Methods: This study used the true experimental method with Post Test Only Control Group Design using 25 mice which will be divided into five groups, namely K (negative control), P (positive control), M1 (borax and honey dose 1), M2 (borax and honey dose 2), M3 (borax and honey dose 3). This study was conducted for 22 days then. Took the duodenal organ on all samples and then made histological preparations with HE staining. Observations were made with an Olympus microscope to see submucosal edema and damage to the epithelium of the duodenal mucosa. Results: The results of the study found that borax 26 mg / head / day had an influence on the histopathological picture of duodenal borax. In addition, the administration of honey dose 75 mg / Kg BB provides a toxic inhibitory effect of borax in the duodenum best among other treatment groups. However, statistically there was no effect of honey administration on the histopathological picture of the duodenum of wistar rats as an inhibitor of the toxic effect of borax (Sodium Tetraborate) with p˃0.05. Conclusion: Statistically it can be concluded that there is no effect of  the administration of honey on the histopathology picture of the duodenum of wistar rats as an inhibitor of the toxic effects of borax (Sodium tetraborate).
Digitalisasi Ekonomi Sebagai Upaya Peningkatan Omzet UMKM di Sentra Industri Kasongan Ratnadewati, Ainina; Widiastuti, Nur; Noviana, Dian
Prosiding Seminar Nasional dan Call Paper STIE Widya Wiwaha Vol 1 No 1 (2023): Prosiding Seminar Nasional dan Call Paper STIE Widya Wiwaha
Publisher : Sekolah Tinggi Ilmu Ekonomi Widya Wiwaha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32477/semnas.v1i1.634

Abstract

This research aims to determine the impact the digital economy which includes gadget ownership, internet use, marketing through E-commerce, and advertising through social media on MSME turnover in the Kasongan Craft Industry Center. The data used are cross- sectional data, the independent variables are: possession of gadgets; and internet usage Internet use consists of: marketing through E-commerce and advertising through social media; while the dependent variable used is MSME turnover. This study uses primary data obtained from 30 samples of MSMEs at the Kasongan Handicraft Industry Center, Bantul Regency. The method used is multiple linear regression using the EVIEWS 10 application. All independent variabel affect dependen variabel. Aspects of the digital economy that affect MSME turnover in the Kasongan Industrial Center, Bantul Regency, namely: gadget ownership, internet use, and advertising through social media. Product marketing through E-commerce has no effect on turnover. This influence indicates that the majority of MSMEs in these centers have implemented the digital economy as a means to market their products. As a result, the marketing of these products increases turnover so that market penetration efforts also increase.
Co-Authors Bintarti, Tri Wahyuni Gumilang, Retna Nur Widiastuti Ratnadewati, Ainina