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DOSIS OPTIMAL ANTI HIPERURICEMIA EKSTRAK ETANOL DAUN SALAM (SYZYGIUM POLYANTHUM) PADA TIKUS PUTIH GALUR WISTAR Gumilang, Retna; Farakhin, Noer
E-Jurnal Medika Udayana Vol 11 No 3 (2022): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2022.V11.i03.P15

Abstract

Kadar asam urat yang tinggi akan menyebabkan peningkatan kristal asam urat yang berbentuk seperti jarum terutama di persendian yang akan menimbulkan rasa sakit pada persendian tersebut. Tumbuhan obat yang digunakan sebagai anti hiperurisemia sangat banyak. Salah satu tanaman yang digunakan sebagai obat tradisional untuk menurunkan kadar asam urat adalah tanaman salam (Syzygium polyanthum Wight). Tujuan penelitian ini adalah menganalisis dosis terapi ekstrak daun salam yang menunjukan efek maksimal dalam menurunkan kadar asam urat darah tikus putih galur wistar yang dibuat hiperurisemia dengan diinduksi jus hati ayam segar. Penelitian ini merupakan penelitian eksperimental labolatorik dengan desain post only control group design. Menggunakan 25 ekor tikus dibagi menjadi 5 kelompok terdiri dari; kontrol negative yaitu tikus putih diberi pakan standar, kelompok kontrol positif yaitu tikus putih yang dibuat hiperurisemia, kelompok perlakuan 1 yang diberi ekstrak daun salam 75 mg/kgBB, kelompok perlakuan 2 yang diberi ekstrak daun salam 150 mg/kgBB, dan kelompok perlakuan 3 yang diberi ekstrak daun salam 300 mg/kgBB. Analisis data dilakukan dengan uji ANOVA dan LSD (Least Significanly Difference) menggunakan program SPSS pada tingkat kepercayaan 95% untuk membandingkan antara kelompok kontrol positif, kelompok kontrol negatif, dan kelompok perlakuan. Hasil analisis statistika menunjukkan ada perbedaan signifikan antara kelompok control negative dengan kelompok control positif, kelompok control positif dengan kelompok perlakuan 2, dan kelompok control positif dengan kelompok perlakuan 3. Tetapi tidak menunjukkan perbedaan yang signifikan antara kelompok control positif dengan kelomok perlakuan 1.
PERAWATAN LUKA RINGAN KEPADA WARGA MIGRAN DI INTERNATIONAL ORGANIZATION OF IMMIGRATION SIDOARJO Bhayusakti, Aditya; Gumilang, Retna; Ayu, Friska
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 6 (2023): Volume 4 Nomor 6 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i6.23454

Abstract

Latar belakang: Kecelakaan atau kejadian yang tidak diinginkan dapat terjadi dimana saja dan kapan saja. Luka adalah hilang atau rusaknya sebagian jaringan tubuh yang disebabkan oleh trauma tajam atau tumpul, perubahan suhu, paparan zat kimia, ledakan, sengatan listrik, maupun gigitan hewan. Sampai saat ini, Indonesia masih menjadi tujuan destinasi para migran dari luar negeri salah satunya untuk mengungsi. Tujuan dari pengabdian kepada masyarakat ini adalah untuk meningkatkan kemampuan migran dalam perawatan luka sederhana jika terjadi hal yang tidak diinginkan. Metode: Metode yang dilakukan pada kegiatan pengabdian kepada masyarakat ini adalah dengan cara pemberian pelatihan perawatan luka. Pematerian diberikan menggunakan bahasa Inggris. Luaran kegiatan ini yaitu untuk meningkatkan pengetahuan peserta mengenai perawatan luka ringan. Soal Pre-test dan post-test diberikan kepada peserta digunakan sebagai indikator tingkat pengetahuan peserta sebelum dan sesudah diberikan materi. Hasil dan pembahasan: Kegiatan pengabdian kepada masyarakat ini telah dilaksanakan selama satu hari pada tanggal 2 Agustus 2023 di International Organization of Immigration Sidoarjo. Sasaran peserta adalah warga Migran di International Organization of Immigration Sidoarjo. Hasil rata-rata nilai pre-test adalah 81, sedangkan nilai rata-rata post-test adalah 76. Hal ini menunjukkan terdapat penurunan rata-rata nilai sebesar 3,3%. Hal ini dapat disebabkan karena berbagai faktor, terutama karena kendala bahasa yang berbeda antara pemateri dan peserta. Kesimpulan: Kegiatan pengabdian masyarakat mengenai perawatan luka ringan ini telah terlaksana dengan hasil akhir tidak menunjukkan adanya peningkatan pengetahuan peserta berdasarkan perbandingan rata-rata nilai pre-test dan post-test.
The Effect of Honey Administration on The Histopathology of The Duodenum of Wistar Rats as a Inhibition of The Toxic Effects of Borax (Sodium tetraborate) Noviana, Dian; Syarifah, Mustika Chasanatusy; Gumilang, Retna; Bintarti, Tri Wahyuni
Jurnal Medis Islam Internasional Vol 4 No 2 (2023): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i2.4445

Abstract

Background: Borax can result in oxidative stress and cause the onset of gastrointestinal ulcerations that will dampen the duodenal villi to become shorter and can even disappear. Cell damage due to oxidative stress can be prevented by administering antioxidants. Antioxidants will inhibit the onset of chain reactions in the formation of free radicals by complementing the existing electron deficiency. Honey is one of the natural ingredients that is rich in antioxidants and part of thibbun Nabawi as one of the inhibitors of the toxic effects of borax. Objective : The purpose of this study is to to analyze the effect of honey administration on the histopathological description of submucosa and epithelial mucosa of duodenal wistar rats as an inhibitor of the toxic effects of borax (Sodium tetraborate). Methods: This study used the true experimental method with Post Test Only Control Group Design using 25 mice which will be divided into five groups, namely K (negative control), P (positive control), M1 (borax and honey dose 1), M2 (borax and honey dose 2), M3 (borax and honey dose 3). This study was conducted for 22 days then. Took the duodenal organ on all samples and then made histological preparations with HE staining. Observations were made with an Olympus microscope to see submucosal edema and damage to the epithelium of the duodenal mucosa. Results: The results of the study found that borax 26 mg / head / day had an influence on the histopathological picture of duodenal borax. In addition, the administration of honey dose 75 mg / Kg BB provides a toxic inhibitory effect of borax in the duodenum best among other treatment groups. However, statistically there was no effect of honey administration on the histopathological picture of the duodenum of wistar rats as an inhibitor of the toxic effect of borax (Sodium Tetraborate) with p˃0.05. Conclusion: Statistically it can be concluded that there is no effect of  the administration of honey on the histopathology picture of the duodenum of wistar rats as an inhibitor of the toxic effects of borax (Sodium tetraborate).
Relationship between Santri's Personal Hygiene to the Incidences of Scabies in Islamic Boarding School Maria Ulfa; Dwi Puspitarini, Marinda; Gumilang, Retna; Ideham, Bariah; Agnovianto, Yuriske
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 9 No 1 (2025): Medical Technology and Public Health Journal March 2025
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mtphj.v9i1.5749

Abstract

Background: Skin diseases are often found in Indonesia, such as scabies which is caused by parasites. Scabies causes damage to the skin and discomfort due to itching. This scabies disease is not paid enough attention by students in Islamic boarding schools, the causes are poor environment, poor personal hygiene, lack of knowledge so that there is a risk of transmission of scabies disease. Therefore, this is a priority that needs to be considered and addressed in order to reduce the risk of transmitting scabies in the Islamic boarding school environment. Research objective: to analyze the relationship between the level of personal hygiene knowledge and the incidence of scabies in Islamic boarding school. Method: This type of research is analytical observational survey study with a cross sectional approach. Data collection uses questionnaires. Sampling is total sampling. Data processing and analysis uses chi square analysis. Results: The results of the Chi Square analysis show that the value of p=0.009 (p<0.05), which means that there is a significant relationship between the level of personal hygiene knowledge and the incidence of scabies in students at Islamic boarding schools. Conclusion: The level of knowledge of students about personal hygiene is one of the factors that can influence the transmission of scabies in the Islamic boarding school environment. So the level of knowledge of students must be increased so that it can be a way to prevent the transmission of scabies.
Correlation Between Workload and Mental Health of Educational Staff Faculty of Medicine Universitas Nahdlatul Ulama Surabaya Azizah AS, Nur; Puspitarini, Marinda Dwi; Gumilang, Retna; Farikhah, Zumrotul; Nafisah, Irma Binti Roudlotul; Bariyah, Khadijah Khairul
Jurnal Medis Islam Internasional Vol 7 No 1 (2025): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v7i1.6489

Abstract

Introduction: High workload among educational staff may adversely impact mental health, leading to stress, fatigue, and anxiety. In academic settings, particularly in medical faculties, complex task demands often result in psychological pressure. This study is essential to understand whether workload influences the mental health of educational staff at the Faculty of Medicine Universitas Nahdlatul Ulama Surabaya (FK UNUSA). Objective: This study aims to analyze the relationship between workload and mental health (burnout) among educational staff at the FK UNUSA. Methods: This quantitative study employed a survey approach. Data were collected using standardized questionnaires measuring two main variables: workload (NASA-TLX) and burnout (Maslach Burnout Inventory). A total of 21 educational staff members participated. Statistical analysis was conducted using the Spearman Rank correlation test to examine the relationship between the two variables. Results: The findings indicate a significant correlation between workload and mental health (p = 0.016). Educational staff with higher workloads tended to experience burnout. However, at the FK UNUSA, most educational staff reported mild to moderate workloads, while their mental health conditions were generally categorized as low to moderate burnout. Conclusions: A significant relationship exists between workload and burnout among educational staff at the FK UNUSA (p-value = 0.016). Although workload is an important factor, it does not act alone. Other contributing factors, such as social support, emotional stress, and work environment, also play critical roles in determining burnout levels.