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Program Pengelolaan Dan Pencegahan Depresi Melalui Pemeriksaan Apolipoprotein A Dan B Pada Kelompok Lanjut Usia Sim, Alfred Sutrisno; Alifia, Khalisya; Aditya, Vincent; Christian, Farell; Destra, Edwin
jurnal ABDIMAS Indonesia Vol. 2 No. 2 (2024): Juni : Jurnal ABDIMAS Indonesia
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jurai.v2i2.1408

Abstract

Depresi adalah kondisi kesehatan mental yang serius dan sering terjadi yang dapat menyebabkan penurunan kualitas hidup dan berbagai komplikasi kesehatan. Apolipoprotein A dan B diketahui memiliki hubungan dengan depresi, sehingga dalam upaya pencegahan dan pengelolaan depresi pada lansia, perlu dilakukan skrining apolipoprotein A dan B. Maka dari itu kegiatan pengabdian masyarakat ini dilaksanakan dengan menggunakan metode PDCA (Plan, Do, Check, Act) untuk memastikan keberlangsungan kegiatan ini dan meningkatkan kualitas kegiatan dengan evaluasi berkelanjutan. Kegiatan ini dilaksanakan dengan edukasi kesehatan mengenai pentingnya nutrisi dan aktivitas fisik, serta dukungan sosial. Hasil menunjukkan bahwa pada lansia, didapatkan kadar apolipoprotein A rata-rata adalah 155.59 mg/dL dan apolipoprotein B rata-rata adalah 93.2 mg/dL. Sebanyak 59.1% lansia tidak mengalami depresi, sementara 20.4% mengalami depresi ringan, 9.7% depresi sedang, dan 10.8% depresi berat. Deteksi dini merupakan hal yang penting sehingga individu dapat mencari yang tepat dapat membantu mengelola kadar apolipoprotein, mengurangi risiko depresi, dan pada akhirnya meningkatkan kualitas hidup lansia.
Strategi Pencegahan Penyakit Kardiovaskular pada Lansia dengan Skrining Lemak Tubuh menggunakan Fat Caliper Priyana, Andria; Santoso, Alexander Halim; Gunaidi, Farell Christian; Lucius, Steven Hizkia; Alifia, Khalisya
Jurnal Pengabdian West Science Vol 4 No 07 (2025): Jurnal Pengabdian West Science
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/jpws.v4i07.2417

Abstract

Abstract: Obesity is an increasing health problem among individuals of productive age and has a significant impact on the risk of chronic diseases. Early detection of obesity is essential to prevent metabolic and cardiovascular complications, particularly in vulnerable populations such as those residing in urban areas. This community service activity was conducted through nutritional status screening using Body Mass Index (BMI) and Waist-to-Hip Ratio (WHR) measurements among 107 productive-age participants in Tanjung Duren Village, West Jakarta. In addition to screening, participants received education on obesity risk factors and prevention strategies. The screening results revealed variations in nutritional status, with 66.36% of participants categorized as obese based on BMI, and 71.03% exhibiting high WHR, indicating central obesity. Anthropometric screening has proven to be effective in the early detection of obesity risk. The educational sessions played an important role in increasing participants' awareness of the importance of adopting a healthy lifestyle to prevent obesity-related complications. This activity successfully identified obesity risk within the community and enhanced knowledge on disease prevention. Routine early detection and educational programs are necessary to improve community quality of life and reduce the burden of obesity-related diseases.  
Peran Apolipoprotein B, Apolipoprotein A, dan Rasio ApoA/ApoB sebagai Prediktor Terjadinya Demensia pada Kelompok Lanjut Usia Sim, Alfred Sutrisno; Santoso, Alexander Halim; Gunaidi, Farell Christian; Alifia, Khalisya; Aditya, Vincent; Destra, Edwin
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.4891

Abstract

Neurocognitive disorders, particularly dementia, affect various cognitive functions such as memory, attention, language, learning, and problem-solving, with the elderly population being the most impacted. The prevalence of dementia is projected to rise to 131 million cases by 2050, posing significant social and economic implications. This study employed a cross-sectional method to evaluate the role of Apolipoprotein A (APOA) and Apolipoprotein B (APOB) in the diagnosis and prevention of dementia in older adults. The results showed that Apolipoprotein A was not significantly correlated with MMSE scores, indicating no clear relationship between APOA and cognitive function. In contrast, Apolipoprotein B demonstrated a significant negative correlation with MMSE, suggesting that increased APOB levels are associated with cognitive decline. Elevated ApoB, linked to increased LDL and oxidative stress, correlated with reduced cognitive function, whereas ApoA, the main component of HDL, is associated with neuroprotective effects. These findings underscore the importance of monitoring lipid profiles, including ApoA and ApoB, in the prevention and management of dementia in the elderly.    
DESCRIPTIVE OF KNOWLEDGE LEVEL ON PARACETAMOL USE AND THE EFFECTIVENESS OF RECOVERY FROM PRIMARY CEPHALGIA AMONG MEDICAL STUDENTS Alifia, Khalisya; Kosasih, Robert
Journal of Pain, Headache and Vertigo Vol. 7 No. 1 (2026): March
Publisher : PERDOSNI (Perhimpunan Dokter Spesialis Neurologi Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2026.007.01.01

Abstract

Primary cephalgia is a commonly experienced neurological condition, frequently self-managed by university students using over-the-counter medications such as paracetamol. While accessible and widely used, improper use of paracetamol—due to limited knowledge—can result in suboptimal symptom relief or serious adverse effects such as overdose and hepatotoxicity. This study aims to describe the level of knowledge regarding paracetamol use and its perceived effectiveness in alleviating primary cephalgia symptoms among medical students class of 2022 and 2024 at Tarumanagara University. This descriptive research utilized a cross-sectional design. Data were collected through a structured and validated questionnaire that assessed students’ knowledge about appropriate dosage, indications, side effects, and contraindications of paracetamol. To evaluate effectiveness, participants rated the intensity of their cephalgia before and after paracetamol intake using a standardized pain scale. The results revealed varied levels of knowledge across the respondents. While a considerable proportion of students demonstrated adequate knowledge—especially regarding dosage and indications—knowledge gaps were evident in understanding potential side effects and overdose risks. Furthermore, a statistically significant positive correlation was identified between higher knowledge scores and greater reported reduction in pain severity after paracetamol use. In conclusion, students with a stronger understanding of paracetamol usage experienced more effective relief of primary cephalgia symptoms. These findings underscore the necessity of targeted educational interventions that promote the rational and safe use of over-the-counter analgesics. Enhancing students’ pharmacological literacy is essential to improving therapeutic outcomes and minimizing the risks associated with self-medication practices.