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All Journal Narra J Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi GEMBIRA (Pengabdian Kepada Masyarakat)
Arifa, Nurwahidatul
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Lichen substances from Teloschistes flavicans (Sw.) Norman: Isolation, crystal structure, and evaluation of their antibacterial activities Ismed, Friardi; Arifa, Nurwahidatul; Nissa, Mentari Q.; Putra, Deddi P.; Orue, Analia IC.; Clegg, Jack K.; Rouaud, Isabelle; Dévéhat, Françoise L.
Narra J Vol. 5 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i2.1463

Abstract

Teloschistes flavicans (Sw.) Norman is a lichen known as the golden-haired lichen. This lichen has been recognized and used in herbal medicine mixtures as an antimicrobial and bioindicator of air pollution that plays a role in ecological systems. The aim of this study was to explore the potential of its secondary metabolites as antibacterial and anticancer agents, particularly against bacterial pneumonia. Two main compounds (vicacinin and parietin) were isolated with chromatography and identified by spectrometry and single-crystal X-ray diffraction. The crystallographic data of vicanicin are reported for the first time. Chromatography and recrystallization methods were used to obtain both compounds with orange (parietin) and white (vicanicin) crystals. Furthermore, these compounds were evaluated for cytotoxicity on keratinocytes (HaCaT) cells and antibacterial activity against pneumonia pathogens (Klebsiella pneumoniae ATCC 1706, Streptococcus pneumoniae ATCC 49619, Moraxella catarhalis ATCC 25240, and Staphylococcus pyogenes ATCC 19615). The cytotoxic activity of these compounds was moderate at the concentration of 50-100 µM. The antibacterial pneumonia activity was relatively weak compared to chloramphenicol. Between the two compounds, vicanicin showed stronger activity than parietin against all strains. Vicanicin was more active against Klebsiella pneumoniae and Staphylococcus pyogenes with minimum inhibitory concentrations of 156±0.77 µM and 156±0.91 µM, respectively. In this study, comprehensive molecular structures of parietin and vicanicin have been successfully elucidated, and their antibacterial and cytotoxic activities have been provided.
PENINGKATAN PENGETAHUAN SANTRI TENTANG PENGGUNAAN OBAT YANG RASIONAL MELALUI EDUKASI DAGUSIBU DI PESANTREN PROF. DR. HAMKA II PADANG Elvionita, Cindy; Ferilda, Siska; Marsellinda, Elsa; Andania, Meiridha Mutiara; Arifa, Nurwahidatul; Putra, Rama Feriska
Jurnal Gembira: Pengabdian Kepada Masyarakat Vol 3 No 04 (2025): AGUSTUS 2025
Publisher : Media Inovasi Pendidikan dan Publikasi

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Abstract

Penggunaan obat yang tidak rasional merupakan salah satu permasalahan kesehatan yang masih sering terjadi di masyarakat, termasuk di lingkungan pesantren. Santri yang menjalani kehidupan secara mandiri rentan melakukan swamedikasi tanpa pengetahuan yang memadai. Edukasi DAGUSIBU (Dapatkan, Gunakan, Simpan, dan Buang) Obat dengan Benar merupakan salah satu pendekatan yang dapat digunakan untuk meningkatkan literasi penggunaan obat yang aman dan bertanggung jawab. Kegiatan pengabdian ini bertujuan untuk meningkatkan pengetahuan santri kelas VII di Pondok Pesantren Prof. Dr. Hamka II Padang tentang penggunaan obat secara rasional melalui metode edukatif dan interaktif. Metode yang digunakan meliputi pemaparan materi, kuis interaktif, sesi tanya jawab, dan diskusi kasus sederhana. Hasil pelaksanaan menunjukkan tingginya partisipasi dan antusiasme santri, serta peningkatan pemahaman terkait klasifikasi obat, cara penyimpanan yang tepat, dan pentingnya membaca informasi pada kemasan obat. Edukasi ini juga mendorong terjadinya perubahan perilaku awal pada peserta, seperti keinginan untuk menyebarkan informasi yang diperoleh kepada teman sebaya. Kegiatan ini membuktikan bahwa pendekatan edukatif berbasis komunitas pesantren efektif dalam meningkatkan kesadaran dan pengetahuan remaja tentang penggunaan obat yang benar. Intervensi semacam ini diharapkan dapat direplikasi di pesantren lain sebagai upaya promotif dalam penguatan literasi kesehatan di kalangan remaja.
Pelatihan Identifikasi Cepat Fitokimia pada Mahasiswa STIFI BP Palembang Ferdian, Arif; Arifa, Nurwahidatul; Bakhtiar, Amri
ABDIKAN: Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi Vol. 2 No. 4 (2023): November 2023
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/abdikan.v2i4.2372

Abstract

Identification of phytochemicals is an important preliminary test that pharmacy students need to know and understand. As is known, that natural ingredients are an important aspect that plays a role in herbal medicine. One of the most prominent uses of plants is as a medicinal ingredient. In determining the traditional use of natural materials, it is necessary to know which groups of chemical compounds are contained in natural materials. Chemical compounds contained in natural products are grouped into alkaloids, phenolics, flavonoids, saponins, steroids and terpenoids. To determine the class of compounds in natural products, it is necessary to carry out preliminary tests quickly, namely by testing phytochemicals. Phytochemical identification training is aimed at STIFI Bhakti Pertiwi Palembang students who conduct field studies at Anai Land, Padang Pariaman Regency, Padang, West Sumatra. This field study activity is held as a support for natural product chemistry lectures. Phytochemical testing was carried out in groups guided by each. Students who have received training can carry out phytochemical testing of natural ingredients as a provision for final project research.
Co-Authors Amri Bakhtiar Clegg, Jack K. Dévéhat, Françoise L. Elsa Marsellinda Elvionita, Cindy Friardi Ismed Mega Fatimah Rosana Meiridha Mutiara Andania Nissa, Mentari Q. Orue, Analia IC. Putra, Deddi P. Putra, Rama Feriska Rouaud, Isabelle Siska Ferilda