Article Per Year (5 Year)
p-Index From 2020 - 2025
0.61
P-Index
This Author published in this journals
All Journal Praeparandi : Jurnal Farmasi dan Sains Indonesian Journal of Chemical Science Welfare: Jurnal Pengabdian Masyarakat
Ananda, Lintang Tri
Unknown Affiliation
Chemistry Environmental Science Medicine & Pharmacology Physics Social Sciences

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
REVIEW ARTIKEL : NANOEMULSI PERAK KOMBINASI KAYU MANIS DAN APLIKASINYA SEBAGAI LOZANGE NR Selay, Risma Eka Putri; Rizkita, Aden Dhana; Ananda, Lintang Tri; ismiati, Silfia; Maulidian, Yuda
Praeparandi : Jurnal Farmasi dan Sains Vol 7 No 1 (2023): Praeparandi : Jurnal Farmasi dan Sains
Publisher : Praeparandi : Jurnal Farmasi dan Sains

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58365/ojs.v7i1.212

Abstract

Nanoemulsi perak combain kayu manis dan aplikasinya sebagai lozange dengan menggunakan tumbuhan ekstrak kayu manis yang bisa menjadi inhibitor terhadap reseptor asetilcolin nicotinate yang terkandung dalam nikotin. Kayu manis (Cinnamomum verum) merupakan salah satu tanaman yang kulit batang, cabang, dan dahannya dapat digunakan sebagai bahan rempah-rempah dan merupakan salah satu komoditas eksport Indonesia serta dapat memiliki nilai lebih jika dibuat dalam bentuk sediaan hard candy lozange . Oleh karena itu, review artikel ini dibuat untuk memberikan informasi berbagai hasil penelitian bahwa nanoemulsi perak combain kayu manis dengan menggunakan tumbuhan ekstrak kayu manis dapat menghambat reseptor asetilkolin nikotinat yang terkandung dalam nikotin. Ekstrak kulit kayu manis ini didapat dengan proses metode maserasi dan metode ultrasonic. Selanjutnya nanoemulsi ekstrak kayu manis yang sudah terbentuk itu dilakukan karakterisasi berdasarkan ukuran partikel potensial zeta dan gugus fungsi. Dilakukan pengujian fitokimia pada ekstrak kayu manis diantaranya pengujian alkaloida, flavonoid, tannin, saponin, steroid dan triterpenoid. Selain dilakukan pengujian fitokimia, terdapat pengujian interaksi kayu manis dengan reseptor yang terdapat dalam nikotin yaitu asetilkolin nikotinat. Terdapat sembilan ligan yang terdapat dalam kayu manis, tetapi setelah diuji menggunakan analisa docking di autodock hanya tiga ligan yang memiliki afinitas yang tinggi yaitu sisquiterpen, fenol dan linalool yang dapat menghambat nAChRy3 (4zk4) dan nAChRy7 (3sq9) sebagai reseptor peran nikotin.
Aksi Sehat Ramah Lingkungan: Edukasi dan Pembagian Sabun Cuci Tangan Berbahan Dasar Minyak Jelantah Maulana, Ilham; Syari, Delviza; Angganawani, Rahmadhani Tyas; Yusup, Ahsan Maulana; Ananda, Lintang Tri; Shapira, Shari Bella; Ismiati, Silfia; Pratiwi, Vivi Amalia Dwi
Welfare : Jurnal Pengabdian Masyarakat Vol. 3 No. 3 (2025): Welfare : September 2025
Publisher : Fakultas Ekonomi dan Bisnis Islam, IAIN Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30762/welfare.v3i3.2602

Abstract

Used cooking oil is a household waste whose environmental and health impacts are often overlooked. Careless disposal can damage soil, water, and ecosystems. This community service aimed to educate the public about processing used cooking oil into environmentally friendly handwashing soap through a participatory-educational approach. Implemented by STIKes Bogor Husada at Sempur Field, Bogor City, as part of its 6th Anniversary, the activity involved direct outreach and distribution of soap made from used oil. A total of 100 bottles were distributed to more than 100 participants. The results showed increased understanding of the dangers of oil disposal and its economic potential if recycled. Positive responses, interest in further training, and wider impact through social media demonstrate that an educational approach with concrete actions is effective in fostering awareness and behavior, while serving as a contribution of higher education institutions in health advocacy and environmental sustainability.
In Silico Interaction Study of the Hydrazine Compound as an Antibody Drug Conjugate Linker Against Pertuzumab Ananda, Lintang Tri; Rizkita, Aden Dhana; Gibran , Syahrul Syah; Shapira, Shari Bella; Nour baety, Shelly Siti; Wafa, Shahibatul; Oksal, Efriyana
Indonesian Journal of Chemical Science Vol. 14 No. 1 (2025): Indonesian Journal of Chemical Science
Publisher : Prodi Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Breast cancer can be initiated, one way or another, by overexpression of the HER-2 protein which can induce dimerization, resulting in metastasis in breast cancer cells. Pertuzumab is one of the methods used to treat metastatic breast cancer that is breast cancer cells that the cancer has spread to other parts of the body. Hydrazine is something hydro nitrogen compounds that has the formula N2H4 molecule. The hydrazine compound has chemical characteristics as a strong reducing agent because hydrazine plays a role as donor group hydrogen can reduce double bonds into single bonds through reaction hydrogenation. Research purposes This is o see the bond between Hydrazine as a linker with pertuzumab as an antibody for development of Antibody Drug Conjugate in silico with molecular docking. The docking method is used to know the conformation and free energy ties involved in the interaction between molecule (pertuzumab) and its ligand (hydrazine). In silico molecular docking was carried out with a number of stages such as ligand preparation, preparation of macromolecules, validation molecular docking method, docking hydrazine with pertuzumab protein and intermediate data analysis optimized hydrazine compound with which pertuzumab protein the lower mark energy bond so the stronger and stable the bond that occurs between hydrazine compound and pertuzumab protein . Obtained the result of docking is in the form of binding affinity from the results of addition of pertuzumab protein with the hydrazine ligand which is -6.8 which shows conformation formed stable or does not require great energy To do binding. Visualization results from complex molecule hydrazine compound against pertuzumab protein own identical confirmation on the part side active binding from pertuzumab protein macromolecules . The hydrazine compound can be bonded with pertuzumab and has potential as a new drug development in the targeting antibody drug conjugate breast cancer.
Co-Authors Angganawani, Rahmadhani Tyas Gibran , Syahrul Syah Ilham Maulana ismiati, Silfia Maulidian, Yuda Nour baety, Shelly Siti Oksal, Efriyana Pratiwi, Vivi Amalia Dwi Rizkita, Aden Dhana Selay, Risma Eka Putri Shapira, Shari Bella Syari, Delviza Wafa, Shahibatul Yusup, Ahsan Maulana