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All Journal RENATA Jurnal Pengabdian Masyarakat Kita Semua Indonesian Journal of Chemical Science Welfare: Jurnal Pengabdian Masyarakat
Shapira, Shari Bella
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Humanities Chemistry Computer Science & IT Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Environmental Science Physics Social Sciences Other

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Pelatihan Pembuatan Sabun Kertas dari Limbah Minyak Jelantah sebagai Solusi Alternatif Produk Ramah Lingkungan Maulana, Ilham; Shapira, Shari Bella; Ismiati, Silfia; Ratiani, Syifa Intan
Welfare : Jurnal Pengabdian Masyarakat Vol. 3 No. 2 (2025): Welfare : June 2025
Publisher : Fakultas Ekonomi dan Bisnis Islam, IAIN Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30762/welfare.v3i2.2251

Abstract

Improper management of used cooking oil waste can cause environmental pollution and negatively impact public health. This community service aims to increase awareness and skills among SMK Tunas Bangsa students in utilizing used cooking oil waste as a raw material for environmentally friendly and economical hand soap production. The method applied is Participatory Action Research (PAR), actively involving students throughout the process, from understanding the waste impact, refining the used oil, to the practical making of paper soap. The results showed significant improvement in students’ knowledge and technical skills, along with high enthusiasm during the training. This activity successfully fostered environmental awareness and opened opportunities for recycling-based entrepreneurship. Main challenges such as limited time and equipment were identified for improvement in future programs. Overall, this community service effectively shaped environmental consciousness and practical skills in students as part of a sustainable solution.
Aksi Sehat Ramah Lingkungan: Edukasi dan Pembagian Sabun Cuci Tangan Berbahan Dasar Minyak Jelantah Maulana, Ilham; Syari, Delviza; Angganawani, Rahmadhani Tyas; Yusup, Ahsan Maulana; Ananda, Lintang Tri; Shapira, Shari Bella; Ismiati, Silfia; Pratiwi, Vivi Amalia Dwi
Welfare : Jurnal Pengabdian Masyarakat Vol. 3 No. 3 (2025): Welfare : September 2025
Publisher : Fakultas Ekonomi dan Bisnis Islam, IAIN Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30762/welfare.v3i3.2602

Abstract

Used cooking oil is a household waste whose environmental and health impacts are often overlooked. Careless disposal can damage soil, water, and ecosystems. This community service aimed to educate the public about processing used cooking oil into environmentally friendly handwashing soap through a participatory-educational approach. Implemented by STIKes Bogor Husada at Sempur Field, Bogor City, as part of its 6th Anniversary, the activity involved direct outreach and distribution of soap made from used oil. A total of 100 bottles were distributed to more than 100 participants. The results showed increased understanding of the dangers of oil disposal and its economic potential if recycled. Positive responses, interest in further training, and wider impact through social media demonstrate that an educational approach with concrete actions is effective in fostering awareness and behavior, while serving as a contribution of higher education institutions in health advocacy and environmental sustainability.
In Silico Interaction Study of the Hydrazine Compound as an Antibody Drug Conjugate Linker Against Pertuzumab Ananda, Lintang Tri; Rizkita, Aden Dhana; Gibran , Syahrul Syah; Shapira, Shari Bella; Nour baety, Shelly Siti; Wafa, Shahibatul; Oksal, Efriyana
Indonesian Journal of Chemical Science Vol. 14 No. 1 (2025): Indonesian Journal of Chemical Science
Publisher : Prodi Kimia

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Abstract

Breast cancer can be initiated, one way or another, by overexpression of the HER-2 protein which can induce dimerization, resulting in metastasis in breast cancer cells. Pertuzumab is one of the methods used to treat metastatic breast cancer that is breast cancer cells that the cancer has spread to other parts of the body. Hydrazine is something hydro nitrogen compounds that has the formula N2H4 molecule. The hydrazine compound has chemical characteristics as a strong reducing agent because hydrazine plays a role as donor group hydrogen can reduce double bonds into single bonds through reaction hydrogenation. Research purposes This is o see the bond between Hydrazine as a linker with pertuzumab as an antibody for development of Antibody Drug Conjugate in silico with molecular docking. The docking method is used to know the conformation and free energy ties involved in the interaction between molecule (pertuzumab) and its ligand (hydrazine). In silico molecular docking was carried out with a number of stages such as ligand preparation, preparation of macromolecules, validation molecular docking method, docking hydrazine with pertuzumab protein and intermediate data analysis optimized hydrazine compound with which pertuzumab protein the lower mark energy bond so the stronger and stable the bond that occurs between hydrazine compound and pertuzumab protein . Obtained the result of docking is in the form of binding affinity from the results of addition of pertuzumab protein with the hydrazine ligand which is -6.8 which shows conformation formed stable or does not require great energy To do binding. Visualization results from complex molecule hydrazine compound against pertuzumab protein own identical confirmation on the part side active binding from pertuzumab protein macromolecules . The hydrazine compound can be bonded with pertuzumab and has potential as a new drug development in the targeting antibody drug conjugate breast cancer.
Pemanfaatan Tanaman Obat Keluarga (TOGA) Sebagai Terapi Non Farmakologis Untuk Pengendalian Hipertensi Di Kampung Situhiang, Desa Puraseda Rodhiah, Widi Siti; Saldaw, Antan; Aqila F, Azahra; Yohanes, Kon; Karlina, Lisda; Meri, Meri; Wahyuni, Nisa Sri; Shapira, Shari Bella; Ismiati, Silfia
RENATA: Jurnal Pengabdian Masyarakat Kita Semua Vol. 3 No. 3 (2025): Renata - Desember 2025
Publisher : PT Berkah Tematik Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61124/1.renata.258

Abstract

Hipertensi merupakan masalah kesehatan yang memerlukan pengendalian melalui terapi farmakologis dan non farmakologis. Pemanfaatan Tanaman Obat Keluarga (TOGA) seperti jahe (Zingiber officinale), kunyit (Curcuma domestica), dan serai (Cymbopogon nardus) sebagai minuman herbal dapat menjadi alternatif dalam menurunkan tekanan darah secara alami. Jahe berperan melalui mekanisme vasodilatasi dan penghambatan Angiotensin-Converting Enzyme (ACE), kunyit sebagai antiinflamasi dan antioksidan, serta serai sebagai diuretik ringan, memberikan efek sinergis untuk menurunkan tekanan darah. Kegiatan pengabdian masyarakat ini dilaksanakan di Kampung Situhiang, Desa Puraseda, Kabupaten Bogor, dengan tujuan meningkatkan pengetahuan masyarakat tentang pemanfaatan TOGA untuk pencegahan hipertensi. Metode yang digunakan adalah edukasi dan demonstrasi pembuatan minuman herbal. Kegiatan ini diikuti oleh 30 peserta dengan antusiasme tinggi. Evaluasi menggunakan kuesioner menunjukkan adanya peningkatan rata-rata nilai pengetahuan dari 79,66 (pre-test) menjadi 97,24 (post-test). Hasil uji beda (Wilcoxon) menunjukkan peningkatan ini signifikan secara statistik (p < 0,001). Kegiatan ini berhasil meningkatkan kesadaran dan kemandirian masyarakat dalam pengendalian hipertensi secara alami dan mempromosikan pemanfaatan tanaman lokal
Co-Authors Ananda, Lintang Tri Angganawani, Rahmadhani Tyas Aqila F, Azahra Gibran , Syahrul Syah Ilham Maulana ismiati, Silfia Karlina, Lisda Meri, Meri Nour baety, Shelly Siti Oksal, Efriyana Pratiwi, Vivi Amalia Dwi Ratiani, Syifa Intan Rizkita, Aden Dhana Rodhiah, Widi Siti Saldaw, Antan Syari, Delviza Wafa, Shahibatul Wahyuni, Nisa Sri Yohanes, Kon Yusup, Ahsan Maulana