Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal HAYATI Journal of Biosciences JITRO (Jurnal Ilmiah dan Teknologi Peternakan Tropis)
Mahendra, Arindina
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Earth & Planetary Sciences Veterinary

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Leukocyte Profile of Dexamethasone-Induced Quail After Administration of Bombyx Mori Silkworm Pupae Extract Santoso, Koekoeh; Mahendra, Arindina; Isdoni, Isdoni; Jumadin, La; Farajallah, Achmad
Jurnal Ilmu dan Teknologi Peternakan Tropis Vol 9, No 2 (2022): JITRO, May
Publisher : Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33772/jitro.v9i2.24061

Abstract

Poultry especially Japanese quails are susceptible to the environmental threat that induced glucocorticoid hormone secretion. Glucocorticoids stimulate oxidative stress and a decrease in the immune system. The purpose of this research is to study the potential of silkworm extract (Bombyx mori) to overcome oxidative stress and reduced the immune system in quails that were induced with dexamethasone as glucocorticoid. Thirty-two adult quails were used and were given dexamethasone. Those quails were divided into 4 groups, four groups were given 0 mg, 0.16 mg/kg, 0.32 mg/kg, and 0.64 mg/kg of silkworm extract for each quail. The parameters that were observed are total leucocyte count, differential leucocyte count, and heterophil/lymphocyte ratio. The results are not significant compared to the groups that were not given any supplements. This study shows that the administration of silkworm extract is not effective for recovery purposes.Keywords: antioxidant, quail, Bombyx mori, dexamethasone
Effects of Physalis angulata Leaf Extract on Female Reproductive Organs Following Busulfan Injection in Rats Satyaningtijas, Aryani; Ekastuti, Damiana Rita; Tarigan, Ronald; Prasetyaningtyas, Wahono Esthi; Adnyane, I Ketut Mudite; Mohamad, Kusdiantoro; Rahmadhani, Elsi; Sulistyana, Yanti; Mahendra, Arindina
HAYATI Journal of Biosciences Vol. 33 No. 2 (2026): March 2026
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.33.2.490-498

Abstract

Physalis angulata L. (ciplukan) is traditionally used as an herbal remedy with anticancer and antioxidant properties. At the same time, busulfan, a chemotherapy alkylating agent, causes gonadotoxicity and oxidative stress that impair female reproduction. This study aimed to evaluate the effect of P. angulata on reproductive function after busulfan administration in female rats. Twenty-five 6-week-old female rats were randomly divided into: Group I (control), Group II (busulfan only), Group III (P. angulata only), Group IV (busulfan followed by P. angulata after 14 days), and Group V (busulfan and P. angulata administered for 28 days). FSHR and LHR expression in the ovaries and MDA levels in the ovaries and uterus were measured to assess reproductive changes. Busulfan showed no significant effect on FSHR and LHR, whereas P. angulata induced downregulation, suggesting a potential negative feedback mechanism on ovarian receptors. Ovarian MDA showed a decreasing trend with combined treatments, while uterine MDA peaked after busulfan but declined markedly with P. angulata, indicating its role in alleviating oxidative stress. In conclusion, P. angulata may modulate hormonal balance in rat ovaries and decrease oxidative stress in the uterus after busulfan treatment.
Co-Authors A.S. Satyaningtijas ACHMAD FARAJALLAH Damiana Rita Ekastuti Isdoni Bustaman Jumadin, La Ketut Adnyane Mudite koekoeh santoso Kusdiantoro Mohamad Rahmadhani, Elsi Sulistyana, Yanti Tarigan, Ronald Wahono Esthi Prasetyaningtyas