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Review Article: Histological Description of Hepars that Experience Fatty Liver Mulianti, Rizki; Linawati, Ni Made
Indonesian Journal of Global Health Research Vol 6 No 5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i5.3593

Abstract

The liver is one of the most vital organs and the largest gland, weighing approximately 1500 grams or 2.5% of the total adult body weight. One of the liver's functions is to metabolize nutrients such as fat, protein, and carbohydrates. Fats are synthesized from carbohydrates and proteins, mainly in the liver. Fat function as a source of energy provides essential fatty acids, and plays an important role in dissolving vitamins. A high-fat diet (HFD) is a diet that involves consuming fatty and high-cholesterol foods which can have the risk of causing an increase in lipid levels in the blood, known as hyperlipidemia. Excessive accumulation of fat in liver cells is called fatty liver. Histologically, Non-alcoholic Fatty Liver Disease (NAFLD) is categorized into two types, namely Non-alcoholic Fatty Liver (NAFL) which shows fatty liver without evidence of inflammation in the form of swelling of hepatocyte cells, and Non-alcoholic Steatohepatitis (NASH), namely the presence of fatty liver accompanied by inflammation in the form of swelling of hepatocyte cells, with or without fibrosis.
Hubungan Siklus Menstruasi, Kualitas Tidur, dan Pengetahuan Siswi dengan Kejadian Anemia di MTs. Negeri 2 Lombok Tengah Nirmala, Suci; Yolanda, Rosalina; Mulianti, Rizki; Karmila, Dany
Bioscientist : Jurnal Ilmiah Biologi Vol. 12 No. 1 (2024): June
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v12i1.10780

Abstract

Anemia is a condition where the number of red blood cells in the body is lower than the normal number. Anemia is a health problem that has a fairly high incidence rate throughout the world. This study aims to determine the relationship between the menstrual cycle, sleep quality and knowledge of female students with the incidence of anemia in MTs. Negeri 2 Central Lombok. This research is an analytical observational study using a cross sectional design. The sampling technique uses a probability sampling technique, namely simple random sampling. The research sample was 100 samples with each sample meeting the inclusion and exclusion criteria. The data obtained were analyzed using the chi-square correlation test. The results of this research showed that 48% of respondents had abnormal menstrual cycles and 52% had normal menstrual cycles. 40% of respondents had poor sleep quality and 60% had good sleep quality. Respondents had poor knowledge as much as 33%, sufficient knowledge as much as 44% and good knowledge as much as 23%. There is a relationship between the menstrual cycle and the incidence of anemia with a p-value of 0.000 and OR 32.143. There is a relationship between sleep quality and the incidence of anemia with a p-value of 0.000 and OR 20.487. There is a relationship between female students' knowledge and the incidence of anemia with a p-value of 0.000 and OR 15.882. There is a significant relationship between the menstrual cycle, sleep quality and knowledge of female students with the incidence of anemia in MTs. Negeri 2 Central Lombok.
Hubungan Usia, Tingkat Pengetahuan, Kepatuhan Antenatal Care (ANC), dan Tingkat Stress Pada Ibu Hamil dengan Kejadian Preeklampsia di RSUD Praya Ziad, Shabrina; Mahayani, Ida Ayu Made; Mulianti, Rizki; Setiawan, Nyoman Cahyadi Tri
MAHESA : Malahayati Health Student Journal Vol 4, No 8 (2024): Volume 4 Nomor 8 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i8.15167

Abstract

ABSTRACT Preeclampsia is a syndrome of hypertension and proteinuria in women who are normotensive before pregnancy, which affects around 2% to 8% of pregnancies worldwide and is one of the leading causes of maternal death in Indonesia. Cases of preeclampsia and eclampsia in Praya Regional Public Hospital, Central Lombok Regency, West Nusa Tenggara Province have increased drastically to 375 cases in 2023. This study aims to determine the relationship between age, level of knowledge, compliance with antenatal care (ANC), and stress levels with the incidence of preeclampsia at Praya Regional Public Hospital. The method used in this research is analytical observational with a case-control approach. The results of the chi-square statistical test show that there is a significant relationship between age and the incidence of preeclampsia (p-value = 0.009, p < α 0.05), there is no significant relationship between the level of knowledge and the incidence of preeclampsia (p-value = 0.464, p > α 0.05), there is no relationship between ANC compliance and the incidence of preeclampsia (p-value = 0.194, (p > α 0.05), and there is no significant relationship between stress levels and the incidence of preeclampsia (p-value = 0.731, p > α 0.05). So, there is a relationship between age and the incidence of preeclampsia at the Praya Regional Public Hospital, but there is no relationship between the level of knowledge, ANC compliance, and stress level with the incidence of preeclampsia at the Praya Regional Public Hospital.  Keywords: Preeclampsia, Age, Knowledge, Stress, Antenatal Care (ANC)  ABSTRAK Preeklampsia adalah sindrom hipertensi dan proteinuria pada perempuan yang normotensif sebelum kehamilan, yang memengaruhi sekitar 2% hingga 8% kehamilan di seluruh dunia dan merupakan salah satu penyebab kematian ibu terbanyak di Indonesia. Kasus preeklampsia dan eklampsia di RSUD Praya, Kabupaten Lombok Tengah, Provinsi Nusa Tenggara barat mengalami peningkatan secara drastis menjadi 375 kasus pada tahun 2023. Penelitian ini bertujuan untuk mengetahui hubungan antara usia, tingkat pengetahuan, kepatuhan antenatal care (ANC), dan tingkat stress dengan kejadian preeklampsia di RSUD Praya. Metode yang digunakan dalam penelitian ini adalah analitik observasional dengan pendekatan case-control. Hasil uji statistik chi-square menunjukkan bahwa terdapat hubungan yang signifikan antara usia dengan kejadian preeklampsia (p-value = 0,009, p < α 0,05), tidak terdapat hubungan yang signifikan antara tingkat pengetahuan dengan kejadian preeklampsia (p-value = 0,464, p > α 0,05), tidak terdapat hubungan antara kepatuhan ANC dengan kejadian preeklampsia (p-value = 0,194, (p > α 0,05), dan tidak terdapat hubungan yang bermakna antara tingkat stress dengan kejadian preeklampsia (p-value = 0,731, p > α 0,05). Jadi, terdapat hubungan antara usia dengan kejadian preeklampsia di RSUD Praya, tetapi tidak terdapat hubungan antara tingkat pengetahuan, kapatuhan ANC, dan tingkat stress dengan kejadian preeklampsia di RSUD Praya. Kata Kunci: Preeklampsia, Usia, Pengetahuan, Stress, Antenatal Care (ANC)
HUBUNGAN ANTARA LINGKAR PERUT, INDEKS MASSA TUBUH DAN KOLESTEROL TOTAL TERHADAP KEJADIAN HIPERTENSI PADA USIA PRODUKTIF DI PUSKESMAS KARANG PULE Wijaya, Putu Depirda Rosandiyasa; Setiarini, Rohmania; Mulianti, Rizki
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 10 No. 1 (2026): APRIL 2026
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v10i1.55206

Abstract

Prevalensi usia produktif yang menderita hipertensi di Provinsi Nusa Tenggara Barat semakin  meingkat setiap tahunnya. Hipertensi pada usia produktif dipengaruhi oleh berbagai faktor antara lain lingkar perut, indeks massa tubuh dan kolesterol total. Tujuan penelitian untuk mengetahui hubungan antara lingkar perut, indeks massa tubuh dan kolesterol total terhadap kejadian hipertensi pada usia produktif di Puskesmas Karang Pule. Penelitian ini merupakan penelitian kuantitatif dengan jenis analitik observasional menggunakan rancangan cross-sectional. Sampel penelitian berjumlah 102 responden dipilih dengan teknik purposive sampling. Pengumpulan data dilakukan dengan cara pengukuran langsung terhadap responden menggunakan instrumen penelitian yaitu timbangan badan, microtoise, alat pengukur kolesterol. Analisis data dilakukan secara univariat dan bivariat (uji Rank Spearman). Hasil penelitian ini menunjukkan sebagian besar responden usia produktif mengalami hipertensi tahap 2 yaitu 63,7%. Terdapat hubungan signifikan antara lingkar perut terhadap kejadian hipertensi (rs = 0,58; p-value = 0,000), indeks massa tubuh (IMT) terhadap kejadian hipertensi (rs = 0,47; p-value = 0,000), dan kolesterol total terhadap kejadian hipertensi (rs = 0,51; p-value = 0,000). Responden dengan lingkar perut beresiko, berpeluang mengalami hipertensi sebanyak 14,131 kali dibandingkan dengan responden dengan lingkar perut normal (OR=14,131; 95%CI:2,623-76,135). Responden dengan kolesterol total tinggi, berpeluang mengalami hipertensi sebanyak 7,597 kali dibandingkan dengan responden dengan kolesterol total normal (OR=7,597; 95%CI:1,369-42,137). Terdapat hubungan yang signifikan antara lingkar perut, indeks massa tubuh dan kolesterol total terhadap kejadian hipertensi di Puskesmas Karang Pule.
ANALISIS KADAR HEMOGLOBIN, AKTIVITAS FISIK, DAN LAMA HEMODIALISIS TERHADAP KUALITAS HIDUP PASIEN PENYAKIT GINJAL KRONIS Hidayaturrizqi, Baiq Humairo; Utama, Lalu Buly Fatrahady; Arjita, I Putu Dedy; Mulianti, Rizki
Jambura Journal of Health Sciences and Research Vol 8, No 2 (2026): APRIL: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v8i2.36728

Abstract

Penyakit ginjal kronis (PGK) pada stadium lanjut memerlukan terapi hemodialisis yang berdampak pada kualitas hidup pasien secara multidimensional. Kebaruan penelitian ini terletak pada penguatan bukti empiris bahwa kualitas hidup pasien hemodialisis tidak selalu dipengaruhi oleh parameter klinis seperti kadar hemoglobin dan tingkat aktivitas fisik, melainkan lebih berkaitan dengan durasi menjalani terapi hemodialisis sebagai proses adaptasi jangka panjang pasien terhadap penyakit kronis. Penelitian ini bertujuan untuk menganalisis hubungan antara kadar hemoglobin, aktivitas fisik, dan lama menjalani hemodialisis dengan kualitas hidup pasien PGK yang menjalani hemodialisis. Penelitian ini menggunakan desain observasional analitik dengan pendekatan cross-sectional terhadap 62 pasien PGK di Unit Dialisis RSUD dr. Soedjono Selong yang dipilih menggunakan consecutive sampling, di mana kadar hemoglobin diperoleh dari data rekam medis, aktivitas fisik diukur menggunakan International Physical Activity Questionnaire–Short Form (IPAQ-SF), dan kualitas hidup dinilai menggunakan WHOQOL-BREF, dengan analisis bivariat menggunakan Fisher’s Exact Test. Hasil penelitian menunjukkan bahwa tidak terdapat hubungan yang signifikan antara kadar hemoglobin (p = 0,328) maupun tingkat aktivitas fisik (p = 0,882) dengan kualitas hidup, sedangkan lama menjalani hemodialisis berhubungan signifikan dengan kualitas hidup pasien PGK (p = 0,000). Kesimpulannya, kualitas hidup pasien PGK yang menjalani hemodialisis lebih dipengaruhi oleh adaptasi terhadap terapi jangka panjang, sehingga intervensi pelayanan kesehatan perlu diarahkan pada pendekatan holistik yang mendukung adaptasi fisik dan psikososial pasien.
AGE, BREASTFEEDING HISTORY, AND HORMONAL CONTRACEPTIVE USE AS PREDICTORS OF BREAST CANCER INCIDENCE AT NTB PROVINCIAL HOSPITAL Mileniasari, Ni Made Srileona; Suanjaya, Made Agus; Pramana, Kadek Dwi; Mulianti, Rizki
International Journal of Health Science & Medical Research Vol 5, No 2 (2026): August 2026
Publisher : UNG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/ijhsmr.v5i2.36787

Abstract

Breast cancer is a major health problem in women whose incidence continues to increase, including in Nusa Tenggara Barat (NTB) Province, so that scientific evidence-based prevention efforts are needed. The novelty of this study lies in the simultaneous analysis of age, breastfeeding history, and hormonal contraceptive use as independent risk factors for breast cancer in the local NTB population using a multivariate approach. This study aims to analyze the relationship between age, breastfeeding history, and hormonal contraceptive use with breast cancer incidence at the NTB Provincial Hospital. The research used an observational analytical design with a retrospective case-control approach, involving 110 respondents (55 cases and 55 controls) and medical record data from 2024, with univariate analysis, a bivariate Chi-Square test, and multivariate logistic regression. The results showed that age 40 years and hormonal contraceptive use were associated with an increased risk of breast cancer, while breastfeeding history was protective, and all three variables remained significant in the multivariate analysis, with hormonal contraceptive use as the most dominant factor. The conclusion of this study states that age, breastfeeding history, and hormonal contraceptive use are independent risk factors for breast cancer. Therefore, strengthening health education, early detection in at-risk groups, and appropriate contraceptive counseling are needed as a breast cancer prevention effort in NTB Province.