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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Indonesian Journal of Global Health research MEDIC MEdical Dedication
Siregar, Mara Imam Taufiq
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Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Physics Public Health

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Correlation Clinicopathological and Immunohistochemical Expression of Interleukin-6 (IL-6) in Keloid Fairuz, Fairuz; Utami, Erisca; Dewi, Hasna; Fitriyanti, Fitriyanti; Miftahurrahma, Miftahurrahma; Justitia, Budi; Siregar, Mara Imam Taufiq; Humaryanto, Humaryanto
Indonesian Journal of Global Health Research Vol 6 No 6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i6.5844

Abstract

IL-6 has been shown to enhance collagen synthesis and prolong the fibroblast proliferative phase, potentially contributing to uncontrolled keloid growth. However, despite its frequent mention in the literature as a crucial factor in keloid formation, studies specifically exploring the molecular mechanisms of IL-6 in fibroblast regulation and its interaction with other cytokines within keloid tissue remain limited. This study aims to further investigate the role of IL-6 in keloid matrix formation. This study is an analytical study conducted cross-sectionally. The samples used were patients diagnosed with keloids histopathologically based on microscopic criteria. Clinical data were taken from medical records and microscopic and immunohistochemical assessments using paraffin blocks available in the anatomical pathology laboratory of hospitals in Jambi city. There were 36 cases of keloids, aged between 12 and 42 years, mostly in women (66.7%), occurring in the trunk area (77.8%) 30 cases of recurrence (83.3%). We found 24 cases (77.8%) with strong IL-6 immunoexpression. There were 3 cases (8.3%) with no immunoexpression. There was a strong correlation between IL-6 immunoexpression and gender (p=0.03), age(0.04) and recurrence (p=0.02). The role of fibroblast cells is very important for the process of collagen formation in wound healing. The role of fibroblast cells is very important for the process of collagen formation in wound healing, where interleukin-6 in various theories and studies supports the process of collagen formation.
SKRINING MYCOBACTERIUM TUBERCULOSIS DENGAN PENGECATAN ZIEHL NEELSEN PADA PELAJAR PONDOK PESANTREN NURUL IMAN DI KOTA JAMBI Karolina, Maria Estela; Lipinwati, Lipinwati; Nuriyah, Nuriyah; Siregar, Mara Imam Taufiq; Hestiningtyas, Maya
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 7 No. 1 (2024): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/medicaldedication.v7i1.32974

Abstract

ABSTRACTMycobacterium tuberculosis is a group of rod-shaped bacteria and acid-fast bacteria that cause infections in the respiratory system or in other body parts such as the brain and bones. Microscopic examination is the easiest, inexpensive and specific examination and can be carried out in all laboratories. For this reason, microscopic examination is the key in carrying out TB control and prevention programs in establishing the diagnosis and evaluation of treatment for TB patients, namely by Ziehl Neelsen staining. Pondok is a dense dwelling and makes Islamic boarding schools often experience health problems. Insufficient ventilation and low sunlight so that the humidity in the room is quite high. Based on this, tuberculosis screening in Islamic boarding schools is important to do. The implementation of this service was carried out at the Nurul Iman Islamic Boarding School, Jambi City, with inclusion criteria for sputum examination with Ziehl Neelsen staining. Staining was carried out in the biomedical laboratory of FKIK UNJA. 23 sputum samples for TB screening did not find Mycobacterium tuberculosis infection with more sample characteristics of male samples with cough <2 weeks. Mycobacterium tuberculosis was not found in students of the Nurul Iman Islamic Boarding School, Jambi City.Keywords: Islamic boarding school, Mycobacterium tuberculosis, Ziehl Nelsen, Sputum ABSTRAKMycobacterium tuberculosis adalah golongan bakteri berbentuk batang dan bakteri tahan asam yang menyebabkan infeksi pada system pernapasan atau pada bagian tubuh yang lain seperti otak dan tulang. Pemeriksaan mikroskopis merupakan pemeriksaan yang paling mudah, murah dan spesifik dan dapat dijalankan di semua laboratorium. Untuk itu pemeriksaan mikroskopis merupakan kunci dalam menjalankan program pengendalian dan pencegahan TB dalam menegakkan diagnosis dan evaluasi pengobatan penderita TB yaitu dengan pengecatan Ziehl neelsen. Pondok merupakan hunian yang padat dan membuat pondok pesantren sering mengalami masalah kesehatan. Ventilasi yang kurang cukup serta cahaya matahari yang rendah sehingga meningkatkan kelembaban di kamar cukup tinggi. Berdasarkan hal tersebut skrining pemeriksaan tuberkulosis di pondok pesantren penting untuk dilakukan. Pelaksanaan pengabdian ini dilakukan di Pondok pesantren Nurul iman Kota jambi, dengan kriteria inklusi untuk dilakukan pemeriksaan sputum dengan pewarnaan Ziehl neelsen. Pewarnaan dilakukan di laboratorium biomedik FKIK UNJA. 23 sampel sputum untuk skrining TB tidak ditemukan infeksi Mycobacterium tuberculosisdengan karakteristik sampel lebih banyak sampel laki-laki dengan batuk <2 minggu. Tidak ditemukan Mycobacterium tuberculosis pada pelajar Pondok pesantren Nurul Iman Kota Jambi.Kata kunci: Pondok pesantren, Mycobacterium tuberculosis, Ziehl Neelsen, Sputum
PENYULUHAN DAN PELATIHAN PENCEGAHAN WABAH DEMAM BERDARAH DENGUE (DBD) SERTA PEMERIKSAAN JENTIK NYAMUK DI PONDOK PESANTREN TANJUNG PASIR AL-AWWABIEN JAMBI Wulandari, Putri Sari; Aryanty, Nindya; Siregar, Mara Imam Taufiq; Iskandar, Mirna Marhami
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 7 No. 1 (2024): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/medicaldedication.v7i1.32996

Abstract

ABSTRACTDengue Hemorrhagic Fever (DHF) is an infectious disease caused by the dengue virus and transmitted through female mosquito vectors of the Aedes aegypti and Aedes albopictus types which are often found in areas with tropical and subtropical climates, especially in urban or semi-urban-areas-and spread quickly and widely. One of the efforts to control dengue fever in Indonesia is Mosquito Nest Eradication (MEN), which is the most effective and efficient strategy to break the chain of dengue transmission by eradicating mosquitoes. The condition of Islamic boarding schools is often associated with an unhealthy environment. When the rainy season arrives, many puddles will appear in the Islamic boarding school environment, both in the inner and outer yards, which can become a breeding ground for mosquitoes. Stagnant water can become a breeding ground for mosquito larvae or larvae which originate from eggs and will grow into adult mosquitoes. The aim of this activity is to increase the knowledge and skills of students at the Tanjung Pasir Al-Awwabien Jambi Islamic Boarding School in an effort to prevent dengue transmission and prevent a dengue outbreak from developing. The method used is outreach in the form of health seminars and training to prevent dengue fever outbreaks. This activity was attended by 93 students consisting of 46 men (49.46%) and 47 women (50.54%). When counseling activities are carried out, activity participants are required to take a pre-test before counseling and a post-test after counseling. The pre-test results showed that most participants had a fair level of knowledge (scores 50-69) at 51.61%, while the post-test results showed that most participants had a good level of knowledge (scores 70-89) at 54.84%. Based on the average results, it was found that participants' test scores increased before and after the counseling activities.Keywords: epidemic, dengue hemorrhagic fever, mosquito larvae, Islamic boarding school, Jambi ABSTRAKDemam Berdarah Dengue (DBD) merupakan penyakit menular yang disebabkan oleh virus dengue dan ditransmisikan melalui vektor nyamuk betina jenis Aedes aegypti dan Aedes albopictus yang seringkali ditemukan di wilayah dengan iklim tropis dan subtropis terutama di daerah perkotaan atau semi perkotaan serta menyebar dengan cepat dan luas. Salah satu upaya pengendalian DBD di Indonesia yaitu Pemberantasan Sarang Nyamuk (PSN) yang merupakan strategi paling efektif dan efisien guna memutus rantai penularan DBD dengan membasmi nyamuk. Kondisi pondok pesantren sering dikaitkan dengan lingkungan yang kurang sehat. Bila musim hujan tiba akan muncul banyak genangan di lingkungan pondok pesantren baik di halaman dalam maupun luar yang dapat menjadi sarana berkembang biak nyamuk. Genangan air dapat menjadi tempat berkembang biak jentik atau larva nyamuk yang berasal dari telur dan akan tumbuh menjadi nyamuk dewasa. Tujuan kegiatan ini adalah meningkatkan pengetahuan dan keterampilan santri Pondok Pesantren Tanjung Pasir Al-Awwabien Jambi dalam upaya pencegahan penularan DBD serta menghindari wabah DBD berkembang. Metode yang digunakan adalah penyuluhan berupa seminar kesehatan dan pelatihan untuk mencegah wabah DBD. Kegiatan ini dihadiri oleh 93 santri yang terdiri dari 46 orang laki-laki (49,46%) dan 47 orang perempuan (50,54%). Saat kegiatan penyuluhan dilaksanakan, peserta kegiatan wajib mengerjakan pre-test sebelum penyuluhan dan post-test setelah penyuluhan. Hasil pre-test menunjukkan paling banyak peserta memiliki tingkat pengetahuan cukup (nilai 50-69) sebanyak 51,61%, sedangkan hasil post-test menunjukkan paling banyak peserta memiliki tingkat pengetahuan baik (nilai 70-89) sebanyak 54,84%. Berdasarkan hasil rerata didapatkan peningkatan nilai test peserta sebelum dan setelah kegiatan penyuluhan.Kata kunci: wabah, demam berdarah dengue, jentik nyamuk, pesantren, Jambi
The Correlation of Fast Food Intake, Breakfast Habits, Vegetable and Fruit Intake, Physical Activity, and Nutritional Status in Students of SMP Negeri 7 Jambi City Suzan, Raihanah; Amini, Afifah; Siregar, Mara Imam Taufiq
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 12 No. 1 (2024): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v12i1.32595

Abstract

Background: Based on the 2018 Riskesdas in Jambi Province, the prevalence of obesity in the 13-15 year age group was 8.13%. Data from the Jambi City Health Office from 2016 to 2018 showed that cases of obesity consistently increased every year. This study aimed to determine the relationship between fast food intake, breakfast habits, vegetable and fruit intake, physical activity, and nutritional status in SMP Negeri 7 Jambi students, Methods: This research is a categorical comparative analytic observational study with a cross-sectional approach. Data were obtained by anthropometric examination; intake of fast food, vegetables, and fruit was obtained from the FFQ, data on breakfast habits were obtained from a questionnaire, and physical activity data were obtained from the IPAQ questionnaire, Results: Most of the 101 respondents were aged 13 years (41.6%), male-dominated by gender (52.5%), and the majority of them were norm weight (54.5%). The frequency of fast food intake is mainly classified as rare, and the type often consumed is chicken nuggets (31.7%). The majority of students never breakfast (33.4%). Most of the respondents rarely consumed vegetables and fruit, and the types of vegetables and fruit that were often consumed were oranges (27.7%) and spinach (24%). Most students have moderate physical activity (48.5%). The results of statistical analysis of fast food (p-value 0.001), breakfast habits (p-value 0.002), physical activity (p-value 0.001), and nutritional status have a significant relationship. In contrast, vegetables and fruit and nutritional status do not have a significant relationship (p-value 0.441), Conclusion: There is a significant relationship between fast food, breakfast habits, and physical activity with nutritional status, and no significant relationship is found between vegetables and fruit and nutritional status. Keywords: Nutritional status, fast food, breakfast habits, vegetables and fruits, physical activity
Co-Authors Amini, Afifah dewi, hasna Fairuz, Fairuz Fitriyanti Fitriyanti Hestiningtyas, Maya Humaryanto, Humaryanto Iskandar, Mirna Marhami Justitia, Budi Lipinwati ., Lipinwati Maria Estela Karolina Miftahurrahma, Miftahurrahma Nindya Aryanty Nuriyah, Nuriyah Putri Sari Wulandari Suzan, Raihanah Utami, Erisca