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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan MEDISAINS Jurnal Ilmiah Universitas Batanghari Jambi ELS Journal on Interdisciplinary Studies in Humanities Indonesian Journal of Global Health research MEDIC MEdical Dedication International Journal of English and Applied Linguistics (IJEAL) JAMAIKA: Jurnal Abdi Masyarakat Jurnal Karya Abdi Masyarakat
Fairuz, Fairuz
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Antidiabetic effect of Psychotria malayana Jack in induced type 1 diabetic rat Fairuz, Fairuz; Dewi, Hasna; Humaryanto, Humaryanto
MEDISAINS Vol 18, No 1 (2020)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v18i1.6909

Abstract

Background: Therapies for hyperglycemic treatment, including insulin and oral diabetes medications, have been confirmed to cause several side effects. Thus, finding new drugs with fewer side effects is of high importance. Salung leaf herb (Psychotria malayana Jack) reported used in traditional societies as a treatment for diabetes. However, the scientific proof of this plant for diabetes treatment is still lacking.Objective: To evaluate the antidiabetic effect of the P. malayana jack in induced type 1 diabetic rats by assessing blood glucose level and pancreatic cells in white rats.Methods: Alloxan used to induce type I diabetes. Rats randomly divided into six groups. A Group P1 received 250 mg/kg BW; group P2 received 500 mg/kg BW, group P3 received 1000 mg/kg BW. While group 4 basal received no treatment, group 5 received distilled water as a negative control, and group 6 received glibenclamide as a positive control. Medications are given for six days. Glucose levels were measured, and observation of pancreatic Langerhans cell damages.Results:  A decrease in blood glucose levels observed in all treatment groups. The most significant reduction (49.76%; 1000 mg/kg BW) occurred in the P3 group. Morphological features of pancreatic Langerhans cell damage were slightly high in the P1 group.Conclusion: P. malayana Jack can consider having an antidiabetic effect in a type 1 diabetic rat by reducing blood glucose levels.
Kliniko-Sitopatologi Lesi Prekanker Leher Rahim di Klinik Unja Smart Desa Mendalo Darat Kabupaten Muaro Jambi Fairuz, Fairuz; Dewi, Hasna; Nuriyah, Nuriyah; Lipinwati, Lipinwati; Ayudia, Esa Indah; Lestari, Nur Afni
Jurnal Karya Abdi Masyarakat Vol. 5 No. 3 (2021): Jurnal Karya Abdi Masyarakat
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (454.739 KB) | DOI: 10.22437/jkam.v5i3.16281

Abstract

Kanker serviks merupakan suatu keganasan yang berkembang di daerah leher rahim. Hampir semua kasus, sebesar 99%, terkait dengan infeksi HPV resiko tinggi. Di Indonesia, angka kejadian kanker berada pada urutan ke-8 di Asia Tenggara, dan urutan ke-23 di Asia. Salah satu skrining kanker serviks yang dapat dilakukan yaitu tes pap smear. Tujuan dari penelitian ini adalah untuk melihat gambaran klinis dan gambaran sitopatologi lesi prekanker leher rahim sesuai dengan klasifikasi Bethesda 2014. Lokasi kegiatan dilakukan di Klinik Unja Smart, Mendalo, Kabupaten Muaro Jambi. Variabel klinis yang dinilai adalah usia, paritas, jenis kontrasepsi, menopause, keluhan, riwayat ginekologi dan status lokalis, sedangkan variabel sitopatologinya adalah gambaran lesi prekanker leher rahim menurut kriteria Bethesda 2014. Didapatkan dari kriteria klinis usia rata-rata adalah 40 tahun, multipara, tidak menggunakan KB dan keluhan terbanyak adalah keputihan. Hasil sitopatologi pap smear terbanyak adalah Negative for intraepithelial lesion or malignancy NILM dan diikuti oleh Servisitis kronis non spesifik (CKNS) di urutan kedua. Kesimpulannya adalah gambaran kliniko-sitopatilogi masih menunjukkan keadaan yang normal.
Pemeriksaan Pap Smear Sebagai Skrining Lesi Prekanker Leher Rahim Fairuz, Fairuz; Dewi, Hasna; Kusdiyah, Erny
Jurnal Karya Abdi Masyarakat Vol. 5 No. 3 (2021): Jurnal Karya Abdi Masyarakat
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (112.712 KB) | DOI: 10.22437/jkam.v5i3.16681

Abstract

Latarbelakang Permasalahan kesehatan reproduksi pada perempuan usia produktif sangat banyak. Salah satu permasalahan yang membuat tingginya tingkat mortalitas perempuan adalah kanker leher rahim. Adanya pemeriksaan sebagai deteksi dini dan penyaring (skrinning) terhadap kanker leher rahim sangat penting dalam menurunkan angka mortalitas Metode Kegiatan ini direncanakan akan diselenggarakan pada bulan Agustus 2019. Lokasi kegiatan akan dilakukan di Klinik Pinang Masak Universitas Jambi. Kegiatan ini dilakukan dengan metode penyuluhan serta pemeriksaan langsung pada peserta kegiatan dan edukasi mengenai pap smear. Hasil Kegiatan dihadiri oleh 35 peserta yang berasal dari civitas akademis dan dharma wanita Universitas Jambi. Setelah penyuluhan dilakukan pemeriksaan pap smear. Sebanyak 19 orang bersedia dilakukan pemeriksaan pap smear. Kesimpulan Pap smear sangat penting dimana tidak hanya efektif untuk mendeteksi (skrinning) kanker leher rahim tetapi juga perubahan sel leher rahim yang dicurigai dapat menimbulkan kanker.
SKIN INFECTION PREVENTION EDUCATION FOR STUDENTS OF TANJUNG PASIR AL-AWWABIEN ISLAMIC BOARDING SCHOOL, JAMBI Husman, Lipinwati; Dewi, Hasna; Hanina, Hanina; Fairuz, Fairuz; Wulandari, Putri Sari
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 1 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Islamic boarding schools are faced health problems with various types of diseases such as skin diseases and TB. Skin diseases can be caused by bacteria, fungi, parasites, which have the potential to be contagious if students does not practice Clean and Healthy Living Behavior (PHBS). For this reason, the community service team from the Faculty of Medicine and Health Sciences, Universitas Jambi provides education regarding PHBS, carries out skin scraping examinations and it’s treatment. PHBS counseling, looking at the level of knowledge from the pretest and posttest results. The objective of this study is to increase knowledge regarding PHBS prevention of skin infections among students at the Tanjung Pasir Al-Awwabien Islamic Boarding School, Jambi. The implementation of community service activities on Sunday, 11 August 2024 at the Tanjung Pasir Al-Awwabien Jambi Islamic Boarding School. The activity is in the form of PHBS counseling for the prevention of skin infections among students boarding at Islamic boarding schools followed by interactive discussions. The counseling was attended by 135 students aged 10 – 20 years, male and female respondents were 74 and 61 people. The respondent's level of knowledge was measured through a questionnaire twice, pretest and posttest which consisted of 13 questions. The results of data analysis from the questionnaire results obtained an average pretest result of 88.5 and an average posttest result of 97.5. There was an increase in the average value of students knowledge regarding PHBS, even though the score was in the very good category. Interactive counseling can increase students' knowledge, and it is hoped that good PHBS knowledge can be applied in their lives.
Mycobacterium Tuberculosis Identification on Suspected Extra Pulmonary Tuberculosis Patients Lipinwati, Lipinwati; Hanina, Hanina; Wulandari, Putri Sari; Iskandar, Mirna Marhami; Istarini, Attiya; Miranda, Melly; Dewi, Hasna; Juniati, Rianita; Fairuz, Fairuz
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 13 No. 1 (2025): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v13i1.38458

Abstract

Background: Extra Pulmonary Tuberculosis (EPTB) is Tuberculosis infection in organs other than the lungs, like pleura, lymph nodes, abdomen, genitourinary tract, skin, joints and bones, or meninges. The Diagnosis of EPTB is still challenging because symptoms of EPTB is vary, location EPTB is an inaccessible site, and paucibacillary smear. We wanted to know the Mycobacterium tuberculosis identification using the qPCR method on samples of EPTB suspects. Methods: This research was a descriptive research with laboratory experiments. Subjects in this study were all cases of suspected EPTB with clinically diagnosed, thoraks radiographs, colonoscopy, and formalin fixed paraffin embedded (FFPE). DNA extraction was carried out according to  PureLink® Genomic dna extraction kit instructions. The PCR volume 20 ul with 2x QuantiNova SYBR Green PCR Kit, M.tuberculosis Primer IS 6110, and DNA Sample. QPCR temperatures was done with predenaturation at 95 °C for 3 minutes, and followed 45 cycles, consist of denaturation at 95 °C for 15 seconds, annealing at 60 °C for 30 seconds dan extenstion at 72 °C for 30 seconds. PCR was performed with positive and negative controls, and data analysis was based on positive and negative ct controls. Results: From 30 suspect EPTB samples, there are males (56,67%), with age 36-55 yo (50%), site of samples most from gastrointestines (70%), and there are 6 samples (20%) with positive qPCR. Conclusion: qPCR methods can be used for EPTB diagnosis.
Personification as a Reflection of Sadness: A Socio-Cultural Stylistic Study in Natsume Soseki's Kokoro Novel Fairuz, Fairuz; Mala Sari, Belia
ELS Journal on Interdisciplinary Studies in Humanities Vol. 8 No. 3 (2025): SEPTEMBER
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34050/els-jish.v8i3.46653

Abstract

Kokoro novel by Natsume Soseki depicts the emotional struggle and loneliness of its characters amidst the pressure of Japan's socio-cultural transformation in the Meiji era, namely the shift from tradition to modernity. The characters' deep sadness is often expressed through the style of personification, making inanimate objects and natural atmospheres seem to have feelings, as a stylistic reflection rich in meaning. This study aims to identify the forms and imagery of personification that reflect the sadness of the main character and analyze the relationship between personification and the socio-cultural context of the Meiji era as a form of response to modernization. The study uses a cognitive stylistic approach (based on Lakoff & Johnson) and a sociocultural approach to see the relationship between language style and the context of changes in community values. The descriptive-qualitative method is carried out through the identification of personification quotes, classification of types, and interpretation of emotional meaning and its relationship to socio-cultural phenomena. The results of the study show that personification appears in nature (wind, sky, rain, fog) and the city atmosphere which emphasizes sadness and alienation. Personification also serves as a medium for emotional expression of characters as well as a subtle critique of socio-cultural turmoil, showing how language constructs and voices emotions in a particular historical context. Through the personification of objects and atmosphere, Natsume Soseki conveys sadness, isolation and anxiety in a society caught in the current of modernization.
Incidence of Gingival Mucosa Karyolysis in the Use of Food Coloring as A Dental Plaque Detection Material (Study on Mus Musculus)” Handayatun, Naning Nur; Rudi, David; Fitria, Karin Tika; Fairuz, Fairuz
Indonesian Journal of Global Health Research Vol 6 No 5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i5.3245

Abstract

Bacteria in dental and oral diseases can lead to systemic issues like kidney and heart disease, emphasizing the importance of maintaining oral hygiene. Disclosing solution, a plaque-revealing agent, is pivotal in assessing plaque removal efficacy. The optimal concentration of rose pink food coloring for plaque visibility is 2.5 g/20 ml water. However, the potential impact of this coloring on oral epithelium remains unstudied. Objective: This research aimed to evaluate the effect of disclosing solution food coloring on the gingival mucosal layer in mice. Pure experimental research with a control group design involved 6 mice (Mus musculus) each in treatment and control groups. Erythrocyn, derived from rose pink food coloring, was applied to mice’s gingiva for 2 minutes daily over 7 days. Labio-gingival epithelial cells were then sampled and analyzed using the modified Feulgen-Roseenbeck method. 58.33% of mice showed karyolysis in gingival epithelial cells, contrasting with no karyolysis in lip mucosa. Careful management of food coloring-containing erythrosine as a plaque detection agent is crucial to prevent contact with oral mucosa or prompt cleaning if contact occurs.
Correlation Clinicopathological and Immunohistochemical Expression of Interleukin-6 (IL-6) in Keloid Fairuz, Fairuz; Utami, Erisca; Dewi, Hasna; Fitriyanti, Fitriyanti; Miftahurrahma, Miftahurrahma; Justitia, Budi; Siregar, Mara Imam Taufiq; Humaryanto, Humaryanto
Indonesian Journal of Global Health Research Vol 6 No 6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i6.5844

Abstract

IL-6 has been shown to enhance collagen synthesis and prolong the fibroblast proliferative phase, potentially contributing to uncontrolled keloid growth. However, despite its frequent mention in the literature as a crucial factor in keloid formation, studies specifically exploring the molecular mechanisms of IL-6 in fibroblast regulation and its interaction with other cytokines within keloid tissue remain limited. This study aims to further investigate the role of IL-6 in keloid matrix formation. This study is an analytical study conducted cross-sectionally. The samples used were patients diagnosed with keloids histopathologically based on microscopic criteria. Clinical data were taken from medical records and microscopic and immunohistochemical assessments using paraffin blocks available in the anatomical pathology laboratory of hospitals in Jambi city. There were 36 cases of keloids, aged between 12 and 42 years, mostly in women (66.7%), occurring in the trunk area (77.8%) 30 cases of recurrence (83.3%). We found 24 cases (77.8%) with strong IL-6 immunoexpression. There were 3 cases (8.3%) with no immunoexpression. There was a strong correlation between IL-6 immunoexpression and gender (p=0.03), age(0.04) and recurrence (p=0.02). The role of fibroblast cells is very important for the process of collagen formation in wound healing. The role of fibroblast cells is very important for the process of collagen formation in wound healing, where interleukin-6 in various theories and studies supports the process of collagen formation.
PEMERIKSAAN KADAR KOLESTEROL DARAH DAN KOMPOSISI LEMAK TUBUH PADA MASYARAKAT MENDALO INDAH DI KLINIK UNJA SMART SEBAGAI SKRINING AWAL HIPERKOLESTEROLEMIA Syauqy, Ahmad; Puspasari, Anggelia; Fairuz, Fairuz; Dewi, Hasna; Utami, Erisca Ayu
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 6 No. 1 (2023): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/medicaldedication.v6i1.26745

Abstract

ABSTRACTMost people are reluctant to be screened hypercholesterolemia. The cause of the reluctance diverse, ranging from the aspect of cost, accessibility to the site inspection, the limitations of the infrastructure as well as aspects of time. It is necessary for community service activities to facilitate this. Activities was held on November 2, 2022, in the form of checks blood pressure and cholesterol levels in the general population who are visiting the Jambi City Governor’s Field during a car free day on Sunday, where on this day, people of the city of Jambi crowded been to Park Jomlo to exercise. The number of people who participated in this examination is 99 people. The examination was conducted using a digital cholesterol checks easy Tauch and after that, participants can consult with a team of dedicated and also receive treatment if their blood pressure and cholesterol levels exceed normal limits. From the implementation of the activity, the results that have normal cholesterol levels are 38 people (38.4%) and abnormal 61 people (61.6%), for examination of body fat composition, which has a percentage of normal body fat 12 people (12%) and abnormal 87 people (88%). While those who have normal visceral fat are 55 people (56%) and the abnormal is 44 people (44%). From the high abnormalities of cholesterol and body fat compositions have been carried out so that it is expected that there is an increase in awareness and understanding of the importance of hypercholesterolemia screening in society.Keywords: cholesterol, hypercholesterolemia ABSTRAKSebagian besar masyarakat enggan untuk melakukan skrining hiperkolesterolemia. Penyebab keengganan tersebut beragam, mulai dari aspek biaya, keterjangkauan ke lokasi pemeriksaan, keterbatasan sarana prasarana maupun aspek waktu. Untuk itu perlu dilakukan kegiatan pengabdian masyarakat untuk memfasilitasi hal tersebut. Kegiatan ini dilaksanakan pada tanggal 2 November 2022 diklinik UNJA Smart Mendalo. Peserta kegiatan ini berjumlah 99 orang yang berasal dari pegawai dan dosen UNJA serta masyarakat yang tinggal disekitar klinik UNJA Smart. Adapun bentuk kegiatannya berupa pemeriksaan tekanan darah, kadar kolesterol, dan komposisi lemak tubuh, konsultasi gratis dengan dokter sekaligus edukasi kesehatan serta juga mendapat pengobatan jika tekanan darah dan kadar kolesterolnya melebihi batas normal. Kegiatan ini akan menggunakan alat cek kolesterol digital easy tauch dan BIA merek omron. Dari pelaksanaan kegiatan didapat hasil yang memiliki kadar kolesterol normal sebanyak 38 orang (38,4 %) dan abnormal 61 orang (61,6%), Untuk pemeriksaan komposisi lemak tubuh , yang memiliki persentase lemak tubuh normal 12 orang (12%) dan abnormal 87 orang (88%). Sedangkan yang memiliki lemak visceral normal sebanyak 55 orang (56%) dan yang abnormal 44 orang (44%). Dari tingginya abnormalitas kadar kolesterol dan komposisi lemak tubuh telah dilakukan edukasi sehingga diharapkan ada peningkatan kesadaran dan pemahaman terhadap pentingnya screening hiperkolesterolemia di masyarakat.Kata kunci: kadar kolesterol, hiperkolesterolemia
Faktor Penyebab yang Paling Dominan Kejadian Dermatitis Kontak Iritan pada Pekerja di TPA (Tempat Pemrosesan Akhir) Talang Gulo Kota Jambi Mawaddah, Rakhmi Aisyah El; Fairuz, Fairuz; Kalsum, Ummi
Jurnal Ilmiah Universitas Batanghari Jambi Vol 24, No 3 (2024): Oktober
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/jiubj.v24i3.5509

Abstract

This study aims to analyze the dominant causal factors of subjective complaints of irritant contact dermatitis in workers at the Talang Gulo Landfill in Jambi City. The data analysis method in this study explains the stages of analysis, namely starting with data collection, data processing and data analysis. Data collection was carried out by the researcher himself and assisted by three enumerators and the head of waste management at the Talang Gulo Landfill. The data that has been obtained is then collected, processed according to the objectives and conceptual framework of the study. After the data is collected, data processing is carried out. Data processing is carried out through the stages of editing, coding, data entry, and data cleaning. The data that has been processed is then analyzed using univariate analysis, bivariate analysis and multivariate analysis. The results of the study showed that the factors related to subjective complaints of irritant contact dermatitis are knowledge, chemical exposure from waste and personal hygiene. Of the three factors, personal hygiene is the most dominant factor in the occurrence of subjective complaints of irritant contact dermatitis. Respondents who have poor personal hygiene have a 6.123 times higher risk of experiencing subjective complaints of irritant contact dermatitis when compared to respondents who have good personal hygiene after being controlled with the variables of knowledge and chemical exposure from waste.
Co-Authors Ahmad Syauqy Anggelia Puspasari ATTIYA ISTARINI dewi, hasna Erny Kusdiyah Esa Indah Ayu, Esa Indah Fitria, Karin Tika Fitriyanti Fitriyanti Handayatun, Naning Nur Hanina, Hanina Humaryanto, Humaryanto Husman, Lipinwati Iskandar, Mirna Marhami Juniati, Rianita Justitia, Budi Khaerudin Khaerudin Lestari, Nur Afni Lipinwati ., Lipinwati Mala Sari, Belia Mawaddah, Rakhmi Aisyah El Miftahurrahma, Miftahurrahma Miranda, Melly Muhammad, Daffasyah Zaki Mulyadi Mulyadi Nuriyah, Nuriyah Putri Sari Wulandari Rudi, David Saputra, Yongki Siregar, Mara Imam Taufiq Sulastri, Tetet Ummi Kalsum Utami, Erisca Utami, Erisca Ayu