Claim Missing Document
Check
Articles

Found 6 Documents
Search

Antidiabetic effect of Psychotria malayana Jack in induced type 1 diabetic rat Fairuz, Fairuz; Dewi, Hasna; Humaryanto, Humaryanto
MEDISAINS Vol 18, No 1 (2020)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v18i1.6909

Abstract

Background: Therapies for hyperglycemic treatment, including insulin and oral diabetes medications, have been confirmed to cause several side effects. Thus, finding new drugs with fewer side effects is of high importance. Salung leaf herb (Psychotria malayana Jack) reported used in traditional societies as a treatment for diabetes. However, the scientific proof of this plant for diabetes treatment is still lacking.Objective: To evaluate the antidiabetic effect of the P. malayana jack in induced type 1 diabetic rats by assessing blood glucose level and pancreatic cells in white rats.Methods: Alloxan used to induce type I diabetes. Rats randomly divided into six groups. A Group P1 received 250 mg/kg BW; group P2 received 500 mg/kg BW, group P3 received 1000 mg/kg BW. While group 4 basal received no treatment, group 5 received distilled water as a negative control, and group 6 received glibenclamide as a positive control. Medications are given for six days. Glucose levels were measured, and observation of pancreatic Langerhans cell damages.Results:  A decrease in blood glucose levels observed in all treatment groups. The most significant reduction (49.76%; 1000 mg/kg BW) occurred in the P3 group. Morphological features of pancreatic Langerhans cell damage were slightly high in the P1 group.Conclusion: P. malayana Jack can consider having an antidiabetic effect in a type 1 diabetic rat by reducing blood glucose levels.
Kliniko-Sitopatologi Lesi Prekanker Leher Rahim di Klinik Unja Smart Desa Mendalo Darat Kabupaten Muaro Jambi Fairuz, Fairuz; Dewi, Hasna; Nuriyah, Nuriyah; Lipinwati, Lipinwati; Ayudia, Esa Indah; Lestari, Nur Afni
Jurnal Karya Abdi Masyarakat Vol. 5 No. 3 (2021): Jurnal Karya Abdi Masyarakat
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (454.739 KB) | DOI: 10.22437/jkam.v5i3.16281

Abstract

Kanker serviks merupakan suatu keganasan yang berkembang di daerah leher rahim. Hampir semua kasus, sebesar 99%, terkait dengan infeksi HPV resiko tinggi. Di Indonesia, angka kejadian kanker berada pada urutan ke-8 di Asia Tenggara, dan urutan ke-23 di Asia. Salah satu skrining kanker serviks yang dapat dilakukan yaitu tes pap smear. Tujuan dari penelitian ini adalah untuk melihat gambaran klinis dan gambaran sitopatologi lesi prekanker leher rahim sesuai dengan klasifikasi Bethesda 2014. Lokasi kegiatan dilakukan di Klinik Unja Smart, Mendalo, Kabupaten Muaro Jambi. Variabel klinis yang dinilai adalah usia, paritas, jenis kontrasepsi, menopause, keluhan, riwayat ginekologi dan status lokalis, sedangkan variabel sitopatologinya adalah gambaran lesi prekanker leher rahim menurut kriteria Bethesda 2014. Didapatkan dari kriteria klinis usia rata-rata adalah 40 tahun, multipara, tidak menggunakan KB dan keluhan terbanyak adalah keputihan. Hasil sitopatologi pap smear terbanyak adalah Negative for intraepithelial lesion or malignancy NILM dan diikuti oleh Servisitis kronis non spesifik (CKNS) di urutan kedua. Kesimpulannya adalah gambaran kliniko-sitopatilogi masih menunjukkan keadaan yang normal.
Pemeriksaan Pap Smear Sebagai Skrining Lesi Prekanker Leher Rahim Fairuz, Fairuz; Dewi, Hasna; Kusdiyah, Erny
Jurnal Karya Abdi Masyarakat Vol. 5 No. 3 (2021): Jurnal Karya Abdi Masyarakat
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (112.712 KB) | DOI: 10.22437/jkam.v5i3.16681

Abstract

Latarbelakang Permasalahan kesehatan reproduksi pada perempuan usia produktif sangat banyak. Salah satu permasalahan yang membuat tingginya tingkat mortalitas perempuan adalah kanker leher rahim. Adanya pemeriksaan sebagai deteksi dini dan penyaring (skrinning) terhadap kanker leher rahim sangat penting dalam menurunkan angka mortalitas Metode Kegiatan ini direncanakan akan diselenggarakan pada bulan Agustus 2019. Lokasi kegiatan akan dilakukan di Klinik Pinang Masak Universitas Jambi. Kegiatan ini dilakukan dengan metode penyuluhan serta pemeriksaan langsung pada peserta kegiatan dan edukasi mengenai pap smear. Hasil Kegiatan dihadiri oleh 35 peserta yang berasal dari civitas akademis dan dharma wanita Universitas Jambi. Setelah penyuluhan dilakukan pemeriksaan pap smear. Sebanyak 19 orang bersedia dilakukan pemeriksaan pap smear. Kesimpulan Pap smear sangat penting dimana tidak hanya efektif untuk mendeteksi (skrinning) kanker leher rahim tetapi juga perubahan sel leher rahim yang dicurigai dapat menimbulkan kanker.
SKIN INFECTION PREVENTION EDUCATION FOR STUDENTS OF TANJUNG PASIR AL-AWWABIEN ISLAMIC BOARDING SCHOOL, JAMBI Husman, Lipinwati; Dewi, Hasna; Hanina, Hanina; Fairuz, Fairuz; Wulandari, Putri Sari
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 1 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Islamic boarding schools are faced health problems with various types of diseases such as skin diseases and TB. Skin diseases can be caused by bacteria, fungi, parasites, which have the potential to be contagious if students does not practice Clean and Healthy Living Behavior (PHBS). For this reason, the community service team from the Faculty of Medicine and Health Sciences, Universitas Jambi provides education regarding PHBS, carries out skin scraping examinations and it’s treatment. PHBS counseling, looking at the level of knowledge from the pretest and posttest results. The objective of this study is to increase knowledge regarding PHBS prevention of skin infections among students at the Tanjung Pasir Al-Awwabien Islamic Boarding School, Jambi. The implementation of community service activities on Sunday, 11 August 2024 at the Tanjung Pasir Al-Awwabien Jambi Islamic Boarding School. The activity is in the form of PHBS counseling for the prevention of skin infections among students boarding at Islamic boarding schools followed by interactive discussions. The counseling was attended by 135 students aged 10 – 20 years, male and female respondents were 74 and 61 people. The respondent's level of knowledge was measured through a questionnaire twice, pretest and posttest which consisted of 13 questions. The results of data analysis from the questionnaire results obtained an average pretest result of 88.5 and an average posttest result of 97.5. There was an increase in the average value of students knowledge regarding PHBS, even though the score was in the very good category. Interactive counseling can increase students' knowledge, and it is hoped that good PHBS knowledge can be applied in their lives.
Mycobacterium Tuberculosis Identification on Suspected Extra Pulmonary Tuberculosis Patients Lipinwati, Lipinwati; Hanina, Hanina; Wulandari, Putri Sari; Iskandar, Mirna Marhami; Istarini, Attiya; Miranda, Melly; Dewi, Hasna; Juniati, Rianita; Fairuz, Fairuz
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 13 No. 1 (2025): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v13i1.38458

Abstract

Background: Extra Pulmonary Tuberculosis (EPTB) is Tuberculosis infection in organs other than the lungs, like pleura, lymph nodes, abdomen, genitourinary tract, skin, joints and bones, or meninges. The Diagnosis of EPTB is still challenging because symptoms of EPTB is vary, location EPTB is an inaccessible site, and paucibacillary smear. We wanted to know the Mycobacterium tuberculosis identification using the qPCR method on samples of EPTB suspects. Methods: This research was a descriptive research with laboratory experiments. Subjects in this study were all cases of suspected EPTB with clinically diagnosed, thoraks radiographs, colonoscopy, and formalin fixed paraffin embedded (FFPE). DNA extraction was carried out according to  PureLink® Genomic dna extraction kit instructions. The PCR volume 20 ul with 2x QuantiNova SYBR Green PCR Kit, M.tuberculosis Primer IS 6110, and DNA Sample. QPCR temperatures was done with predenaturation at 95 °C for 3 minutes, and followed 45 cycles, consist of denaturation at 95 °C for 15 seconds, annealing at 60 °C for 30 seconds dan extenstion at 72 °C for 30 seconds. PCR was performed with positive and negative controls, and data analysis was based on positive and negative ct controls. Results: From 30 suspect EPTB samples, there are males (56,67%), with age 36-55 yo (50%), site of samples most from gastrointestines (70%), and there are 6 samples (20%) with positive qPCR. Conclusion: qPCR methods can be used for EPTB diagnosis.
Personification as a Reflection of Sadness: A Socio-Cultural Stylistic Study in Natsume Soseki's Kokoro Novel Fairuz, Fairuz; Mala Sari, Belia
ELS Journal on Interdisciplinary Studies in Humanities Vol. 8 No. 3 (2025): SEPTEMBER
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34050/els-jish.v8i3.46653

Abstract

Kokoro novel by Natsume Soseki depicts the emotional struggle and loneliness of its characters amidst the pressure of Japan's socio-cultural transformation in the Meiji era, namely the shift from tradition to modernity. The characters' deep sadness is often expressed through the style of personification, making inanimate objects and natural atmospheres seem to have feelings, as a stylistic reflection rich in meaning. This study aims to identify the forms and imagery of personification that reflect the sadness of the main character and analyze the relationship between personification and the socio-cultural context of the Meiji era as a form of response to modernization. The study uses a cognitive stylistic approach (based on Lakoff & Johnson) and a sociocultural approach to see the relationship between language style and the context of changes in community values. The descriptive-qualitative method is carried out through the identification of personification quotes, classification of types, and interpretation of emotional meaning and its relationship to socio-cultural phenomena. The results of the study show that personification appears in nature (wind, sky, rain, fog) and the city atmosphere which emphasizes sadness and alienation. Personification also serves as a medium for emotional expression of characters as well as a subtle critique of socio-cultural turmoil, showing how language constructs and voices emotions in a particular historical context. Through the personification of objects and atmosphere, Natsume Soseki conveys sadness, isolation and anxiety in a society caught in the current of modernization.