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All Journal Jurnal Pembelajaran dan Biologi Nukleus Jurnal Kesehatan Tambusai Herbal Medicine Journal
Sari, Mesi Puspita
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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The Utilisation of Coconut Water Waste into Nanocellulose and Potential Synergistic Effect of Asthma Plant (Euphorbia hirta L.) Extract as an Antibacterial Agent Barus, Lydia Br; Manihuruk, Fani Nuryana; Sari, Mesi Puspita; Simanjuntak, Helen Anjelina; Ginting, Junius Gian; Purba, Hermawan
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 9, No 3: Jurnal Pembelajaran Dan Biologi Nukleus November 2023
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v9i3.5060

Abstract

Skin infections contribute to one of the most significant global health issues. Acne, blisters, and abscesses are examples of skin infections that can be induced by Propionibacterium acnes, Staphylococcus aureus, and Staphylococcus epidermidis. Treatment can be attempted through the development of nanotechnology in the form of nanocellulose. Nanocellulose, an organic substance, can be produced through the conversion of coconut water waste and Acetobacter xylinum bacteria. Future applications of nanocellulose formulated with a blend of extracts derived from natural sources, including Patikan Kebo (Euphorbia hirta L.), are anticipated to include the treatment of wound dressings (patches). Determining the antibacterial potential of nanocellulose was the objective of this study. The experimental research technique is implemented in phases. The extraction process was conducted by means of maceration, while the parallel streak method was utilized for antibacterial testing. The findings of the study indicated that the mean zone of inhibition for each treatment variable was as follows: 0 mm, 15.1 mm, 23.53 mm, and 23.06 mm for nanocellulose (serving as the negative control), nanocellulose and 0.5% extract, 1% extract, 1.5% extract, and clindamycin, respectively. Conclusion: Antibacterial activity was observed in nanocellulose extracts containing 1% and 1.5%
VALIDASI METODE ANALISA KADAR FENOLIK EKSTRAK ETANOL PATIKAN KEBO (Euphorbia hirta L) DENGAN MENGGUNAKAN SPECTROSCOPY UV- VIS Sari, Mesi Puspita
Herbal Medicine Journal Vol 7 No 1 (2024): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v7i1.101

Abstract

Validation research has been carried out on the phenolic content analysis method using the DPPH method on the ethanol extract of Patikan Kebo. In this research, the patikan kebo leaves were previously characterized microscopically and macroscopically and a phytochemical screening test was carried out to determine the secondary metabolite content in the patikan kebo leaves. Next, extraction is carried out using the maceration method. The resulting extract is then analyzed to determine the phenolic content in the sample. Determination of phenolic content uses a method that is first calibrated, which includes linearity, LOD and LOQ, precision, accuracy and sensitivity. The results of each analytical parameter analysis are as follows: linearity = 0.9909, precision = 0.046; 0.06; 0.019 recovery = 98 and 102 %, sensitivity = 1.02. 105 L. Mol-1 cm-1. Analysis of the phenolic sample showed a concentration value of 36.3 mg GAE/gram of patikan kebo extract.
GAMBARAN JUMLAH TROMBOSIT PADA PASIEN MALARIA Plasmodium falciparum DI RUMAH SAKIT KASIH HERLINA TIMIKA PAPUA Sari, Mesi Puspita; Putri, Novita Eka; Solikah, Monika Putri
Jurnal Kesehatan Tambusai Vol. 5 No. 3 (2024): SEPTEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i3.32998

Abstract

Malaria merupakan penyakit infeksi yang disebabkan oleh parasit dari genus Plasmodium yang menyerang sel eritrosit. Tujuan dari penelitian ini yaitu untuk mengetahui jumlah trombosit pasien berdasarkan jenis Plasmodium falciparum, karakteristik berdasarkan usia, dan jenis kelamin di Rumah Sakit Kasih Herlina Timika Papua. Jenis penelitian yang digunakan dalam penelitian ini adalah kuantitatif non-eksperimen dengan jenis deskriptif observasional. Teknik pengambilan sampel yang digunakan adalah teknik Purposive Sampling yang sesuai dengan kriteria inklusi dan ekslusi. Hasil dalam penelitian ini menunjukkan bahwa jumlah trombosit pada pasien malaria Plasmodium falciparum 59,1% orang trombositopenia (<150.000/mm3) sedangkan 40,9% orang lainnya masuk dalam kategori normal (150.000 - 450.000/mm3). Berdasarkan umur jumlah trombosit normal yaitu terbanyak pada rentang usia dewasa 19-59 tahun dengan jumlah 27 orang (30,7%). Sedangkan dengan jumlah trombosit < normal terbanyak pada rentang usia dewasa 19-59 tahun dengan jumlah 38 orang (43,2%). Berdasarkan jenis kelamin pada pasien laki-laki lebih tinggi yaitu sejumlah 54,5%, sedangkan pada Perempuan 45,5%. Kesimpulan dalam penelitian ini adalah jumlah trombosit pada pasien malaria Plasmodium falciparum terbanyak trombositopenia (<150.000/mm3). Umur jumlah terbanyak pada rentang usia dewasa 19-59 tahun. Jenis kelamin laki-laki terbanyak menderita Plasmodium falciparum 54,5% orang.
Co-Authors Ginting, Junius Gian Helen Anjelina Simanjuntak Lydia Br Barus Manihuruk, Fani Nuryana Purba, Hermawan Putri, Novita Eka Solikah, Monika Putri