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All Journal Jurnal Pembelajaran dan Biologi Nukleus Indonesian Journal of Pharmaceutical and Clinical Research Community Development Journal: Jurnal Pengabdian Masyarakat Journal of Natural Sciences Jurnal Sains dan Teknologi Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi Jurnal Pengabdian Masyarakat Bangsa Nusantara Scientific Medical Research Journal Herbal Medicine Journal Jurnal Kesehatan Bakti Tunas Husada
Ginting, Junius Gian
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Metabolit Sekunder Ekstrak Etanol Daun Sukun (Artocarpus altilis (Parkinson) Fosberg) dan Potensinya Sebagai Obat Junius Gian Ginting
Journal of Natural Sciences Vol 3, No 3 (2022): Journal of Natural Sciences November
Publisher : Mahesa Research Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34007/jonas.v3i3.304

Abstract

Breadfruit plants have been used as traditional medicine. Parts of medicinal plants are latex, roots, bark and leaves which are used to treat fractures, sprains, diarrhea, abdominal pain, dysentery, infectious diseases, headaches, hypertension, diabetes, asthma, hepatitis, and inflammation. This study aims to determine secondary metabolites and characterization of breadfruit leaves. The research method was carried out experimentally with extraction by maceration method, and phytochemical screening on simplicia and extracts for identification of secondary metabolites. The secondary metabolites of simplicia and extracts showed the presence of flavonoid compounds, saponins and tannins. Characterization showed the presence of water content of 7.32%, water soluble extract and ethanol content of 12.29% and 8.60%, total ash content and insoluble in acid were 8.50% and 2.34%, respectively. The conclusion of the study is that the secondary metabolites of breadfruit leaves have the potential as medicinal ingredients and the simplicia characterization has met the simplicia standard.
Peningkatan Pengetahuan Pola Hidup Bersih dan Sehat serta Penggunaan Vitamin pada Anak di Panti Asuhan Claresta Nasri Nasri; Vera Estefania Kaban; Hariyadi Dharmawan Syahputra; Junius Gian Ginting; Chyntia Glori Tania
ABDIKAN: Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi Vol. 2 No. 1 (2023): Februari 2023
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/abdikan.v2i1.1712

Abstract

Achieving a healthy lifestyle requires a series of consistent steps, such as regular exercise, eating healthy and nutritious foods, getting enough rest, implementing a clean and healthy lifestyle, and consuming vitamins to boost external immunity. There is also concern about improving the health of children and adolescents, especially children who may have a minimal immune system that needs to be strengthened. The purpose of this activity is to provide education and counseling on how to live a clean and healthy lifestyle and to provide knowledge to children about the use of vitamins. The method of this activity is that children are first given questions for a pre-test about a clean and healthy lifestyle and vitamins, then present the material and close it with a post-test. As a result, only 8,57% of the students knew what a healthy lifestyle and vitamins were at the time of the pre-test. After the presentation of the material, the increase in children's knowledge increased by an average of 86,1%. The activity's conclusion is that it can teach children about living a healthy lifestyle and consuming vitamins. .  
Pengujian Efek Hipoglikemik Fraksi Petroleum Eter dan Etil Asetat Daun Dandang Gendis (Clinacanthus nutans (Burm. F.) Lindau) Junius Gian Ginting
Herbal Medicine Journal Vol 5 No 2 (2022): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (420.611 KB) | DOI: 10.58996/hmj.v5i2.51

Abstract

The investigation had been done about hypoglycaemic effect from Clinachanthus nutans (Burm f.) Lindau extract, which in petroleum ether extract and ethyl acetate extract, that used Glucose Method Tolerance for Mice. The extract of Clinachanthus nutans (Burm f.) Lindau leave was carried out by masseration and using ethanol 80% as solvent, and gradually fractination for ethanol extract with petroleum ether and ethyl acetate solvent. Further, the glucose tolerance had been done for petroleum ether fraction and ethyl acetate. The mice was fasting during 17 hours and the blood glucose level and weight of mice was measured and given the 50% glucose liquid with dose 4 mg/kg bw. After 30 minutes the blood glucose level can be measure again. Divided the mice to 6 group, Group I: control (CMC 0,5% dose 1 % bw); Group II until Group V given the petroleum ether fraction and ethyl acetate fraction with dose 15, 30, 45 dan 60 mg/kg bw; Group VI: given the Glibenclamid suspension dose 1 mg/kg bw as equal. Fixed blood glucose level of mice after 60, 90, 120, 150 and 180 minutes to have use of glucometer (EZ Smart). The result showed that petroleum ether extract doesn’t have hypoglycaemic effect, but in dose 45 and 60 mg/kg bw has given hypoglycaemic effect which to get near Glibenclamid suspension in dose 1 mg/ kg bw with blood glucose level decrease 0,05 (ɑ=0,05).
Validasi Metode Analisa Kadar Fenolik Ekstrak Etanol Jahe Merah (Zingiber officinale var rubrum rhizoma) dengan Spektroscopy UV-Vis Hermawan Purba; Bonar Sinaga; Junius Gian Ginting
Herbal Medicine Journal Vol 6 No 1 (2023): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v6i1.78

Abstract

A validation study of the phenolic content analysis method has been carried out using the Galic acid method for jahe merah. Jahe merah in this study was previously characterized microscopically and macroscopically and a filter phytochemical test was carried out to determine the content of secondary metabolites in jahe merah. Furthermore, extraction is carried out by the maceration method. The resulting extract was then analyzed to determine the phenolic content in the sample. Determination of phenolic content uses a method that has been calibrated first, which includes linearity, LOD and LOQ, precision, accuracy, and sensitivity. The results of the analysis of the analytical parameters are as follows: linearity = 0.9909, Precision = 0.046; 0.06; 0.019 recovery = 98 and 102 %, sensitivity = 1.02. 105 L. Mol-1 cm-1. Analysis of the phenolic sample of the sample showed a concentration value of 180,2 mg GAE/gram jahe extract.
Edukasi Pencegahan Stunting Pada Anak di Desa Mekar Sari Kecamatan Delitua Kabupaten Deli Serdang Sarma Dewi Kemala; Sahat Sinaga; Junius Gian Ginting; Hermawan Purba; Dame Meldaria Sipahutar; Afrida Yelni
Jurnal Pengabdian Masyarakat Bangsa Vol. 1 No. 6 (2023): Agustus
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v1i6.268

Abstract

Stunting merupakan masalah kesehatan yang berdampak pada penurunan kualitas sumber daya manusia. Stunting ditandai dengan tinggi badan lebih pendek dan berat badan rebih rendah dari normal. Salah satu upaya pencegahan stunting adalah memberikan edukasi kepada masyarakat terutama para ibu di Desa Mekar Sari Kecamatan Delitua Kabupaten Deli Serdang. Kegiatan pengabdian bertujuan untuk memberikan pengetahuan dan wawasan kepada orang tua terutama Ibu dalam hal mencegah stunting melalui sosialisasi pemberian makanan gizi seimbang, pemberian ASI Ekslusif dan perilaku hidup bersih dan sehat. Kegiatan dilaksanakan pada hari Sabtu 24 Juni 2023 di rumah warga. Hasil kegiatan dihadiri oleh 25 orang ibu yang telah mampu memahami kegiatan pencegahan stunting melalui pemberian makanan bergizi, pemberian ASI Ekslusif dan tindakan sanitasi.
Potensi Buah Andaliman (Zanthoxylum acanthopodium DC.) sebagai Antibakteri Terhadap Salmonella typhi Helen Anjelina Simanjuntak; Hermawan Purba; Cander Pasaribu; Junius Gian Ginting; Rahmiati Rahmiati; Toberni S Situmorang
Journal of Natural Sciences Vol 4, No 2 (2023): Journal of Natural Sciences Juli
Publisher : Mahesa Research Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34007/jonas.v4i2.404

Abstract

Typhoid fever is a major disease of death in the medical field caused by Salmonella typhi infection with symptoms including fever, mucosal lesions, vomiting, diarrhea, fluid loss, septicemia, and peritonitis. The use of natural plants to cure infectious diseases such as andaliman fruit. The aim of this study was to determine the antibacterial activity of Andaliman fruit extract on the growth of Salmonella typhi. Experimental research method. The Kirby-bauer method was used for the antibacterial test, the maceration method was used for extraction. The results of phytochemical compounds found flavonoids, tanins, saponins, tannins, alkaloids steroids, and triterpenoids in simplicia and andaliman fruit extracts. All extracts have the potential to inhibit the growth of Salmonella typhi, with the diameter of the inhibition zone consisting of 10.04 mm, 12.22 mm, 15.46 mm and 16.68 mm in the strong category. These doses are 10%, 30%, 50%, and 70%. The analysis shows the potential of Andaliman fruit extract as an antibiotic in the treatment of typhoid fever.
Lip Cream Formulation from Miana Leaf Extract (Coleus scutellarioides L.) As A Natural Dye Vera Estefania Kaban; Nasri Nasri; Hariyadi Dharmawan Syahputra; Junius Gian Ginting
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 2 No. 02 (2023): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/nsmrj.v2i02.80

Abstract

Abstrack The miana leaves (Coleus scutellarioides L.) contain flavonoids that can provide specific dyes. The purpose of the study was to formulate miana leaf extract in lip cream preparations as natural dyes. The use of natural lip cream dyes is a solution to overcome the problem of synthetic lip cream dyes. One of the plants such as the miana leaves contains secondary metabolites, one of which is flavonoids which can provide dyes. The natural colors found in miana leaves can be used as natural dyes in cosmetics. The purpose of the study was to determine at what concentration the miana leaves produced the most optimal physical quality of color in the preparation of lip cream. The method of the research includes the manufacture of ethanol extract of miana leaves (Coleus scutellarioides L.) by maceration for 5 days with 96% ethanol solvent and followed by remeseration with the same solvent. The extract formulas used were 5%, 10%, and 15%. The evaluations included organoleptic, homogeneity test, physical test, pH test, irritation test and color preference test. The results of the lip cream preparation, the results of the organoleptic examination were declared to have a semi-solid dosage form, a distinctive odor and varied colors F1, cream color, F2 salmon red, F3 brick red, homogeneity examination results were declared homogeneous, the results of observation of the preparation did not state that there was no change on the shape, color and odor of the preparation, the average pH test results were 4.1, the test results were declared non-irritating, the result of the color preference of the three formulas that the panelists preferred was a concentration of 15% because the color was clear and very soft. Miana leaf ethanol extract can be made as a colorant in lip cream preparations.
OPTIMALISASI MANFAAT MINYAK KARO DI DESA TANGKAHAN Helen Anjelina Simanjuntak; Hermawan Purba; Defacto Firmawati Zega; Junius Gian Ginting
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 4 (2023): Volume 4 Nomor 4 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i4.20427

Abstract

Minyak karo merupakan produk minyak olahan yang dihasilkan oleh masyarakat suku karo yang telah diwariskan secara turun-temurun. Minyak karo berbahan herbal yang digunakan oleh masyarakat suku karo terutama dalam menjaga kesehatan dan pengobatan terutama dalam mengobati masuk angin, pegal linu, terkilir, pergeseran sendi, asam lambung, sakit kepala, alergi, mengobati luka, gatal-gatal dan disengat hewan berbisa. Desa Tangkahan merupakan salah satu desa dengan mayoritas dihuni oleh masyarakat suku karo dengan pekerjaan utama sebagai petani. Beberapa diantara memiliki potensi sebagai pengobat/peracik minyak karo, akan tetapi tidak dikembangkan secara optimal. Kegiatan bertujuan untuk memberikan informasi kepada masyarakat tentang manfaat minyak karo serta cara mengoptimalkannya. Metode kegiatan berupa seminar dan sosialisasi kepada masyarakat tentang manfaat minyak karo serta cara mengoptimalkannya melalui aspek kesehatan, dan aspek pengolahan. Kegiatan dihadiri oleh 40 peserta. Hasil kegiatan menunjukkan adanya antusias dari masyarakat tentang optimalisasi minyak karo melalui pendekatan aspek manfaat dalam kesehatan serta aspek pengolahan yang optimal.
Optimation of Green Synthesis Biopolymer Cellulose Using Acetobacter xylinum From Whey as Media of Bacteria Suharni Sinaga; Junius Gian Ginting; Helen Anjelina Simanjuntak; Dame Meldaria sipahutar; Defacto Firmawai Zega; Yanti Yanti; Sahat Sinaga; Lydia Barus; Hermawan Purba
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS (JPBN) Vol 9, No 3 (2023): Jurnal Pembelajaran Dan Biologi Nukleus November 2023
Publisher : Fakultas Keguruan dan Ilmu Pendidikan Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v9i3.5067

Abstract

Utilizing waste into a more valuable commodity was one of the objectives of that research. Waste which initially became an environmental pollutant factor could be processed into more useful products. Tofu liquid waste was referred to whey was a by-product of tofu production. Whey was waste that still contains organic materials such as protein, fat, carbohydrates and minerals. That whey was used as a growth medium for Acetobacter xylinum bacteria and produces cellulose biopolymer as a result of carbohydrate fermentation. The process of optimizing carbohydrate fermentation by Acetobacter xylinum bacteria was carried out by varying the ratio of the amount of whey to coconut water, the acidity level of the media, and the fermentation time. The research results showed that the biosynthesis of cellulose biopolymer was obtained from a ratio of whey concentration to coconut water of 1:1, variations in acidity levels showed that the optimum fermentation conditions occurred at pH 4, and the optimal amount of cellulose biopolymer was obtained on day 21, namely with the highest percent yield value. The resulting biocellulose was characterized using FTIR, XRD, and SEM. The characterization results show that biocellulose is well formed with a fiber surface shape and particle size in the range of 50-200 nm
Uji Efektivitas Gel Ekstrak Daun Jarak Pagar (Jatropha Curcas L.) sebagai Penyembuhan Luka Sayat Vera Estefania Kaban; Ginting, Junius Gian; Nasri, Nasri; Sagala, Hasel Untung Bersinar; Tarigan, Serly Annisa Br
INSOLOGI: Jurnal Sains dan Teknologi Vol. 3 No. 4 (2024): Agustus 2024
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v3i4.3975

Abstract

Indonesia is known for having abundant biological riches and many plants that can be used as medicine. One of the medicinal plants that is often used by Indonesian people is Jatropha curcas leaves. Jatropha plants are currently used as traditional medicine to treat wounds. One common medication used for cuts is povidone iodine which is effective against bacterial infections. However, povidone iodine also has side effects such as irritation, toxic reactions and burning skin. Jatropha leaves have strong antioxidant activity, so it is necessary to innovate in wound treatment using natural ingredients in the form of gel preparations. The gel preparation was chosen because it is practical, not sticky, easily absorbed by the skin, and works directly on wound tissue. The aim of this study was to assess how well a gel made from ethanol extract of jatropha leaves accelerates the healing of cut wounds in white mice. Jatropha curcas leaves were extracted using the maceration method using 96% ethanol as the solvent. Gel stability testing was carried out organoleptically, homogeneity test and spreadability test. Jatropha leaf extract gel was tested on mice that had been given incisions 1.4 cm long with formulations of 10%, 15% and 20% jatropha leaf extract concentrations. Observations were carried out for seven days. Research findings showed that giving white rats gel containing jatropha leaf extract significantly accelerated their ability to repair wounds
Co-Authors Afrida Yelni Barus, Syafril Bonar Sinaga Cander Pasaribu Chyntia Glori Tania Daeli, Mestika Clemesiya Yulianti Dame Meldaria sipahutar Dame Meldaria Sipahutar Defacto Firmawai Zega Defacto Firmawati Zega Hariyadi Dharmawan Syahputra Hariyadi Dharmawan Syahputra Hasibuan, Poppy Anjelisa Zaitun Helen Anjelina Simanjuntak Ismadi Sihombing Kemala, Sarma Dewi Lydia Br Barus Manihuruk, Fani Nuryana Nasri Nasri Nasri Nasri Purba, Hermawan Rahmiati Rahmiati Sagala, Hasel Untung Bersinar Sahat Sinaga Sahat Sinaga Sari, Mesi Puspita Sarma Dewi Kemala Sinaga, Sahat Singarimbun, Nurbaiti Br Suharni Sinaga Tarigan, Serly Annisa Br Toberni S Situmorang Vera Estefania Kaban Vera Estefania Kaban Wahyuni, Sri Yanti Yanti Yuandani Zega, Defcato Firmawati