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Purba, Hermawan
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Phytochemical screening of bunga rosella (Hibiscus sabdariffa L) and antimicrobial activity test Hermawan Purba; Helen Anjelina Simanjuntak; Risanti Situmorang
Jurnal Pendidikan Kimia (JPKim) Vol 12, No 2 (2020): August
Publisher : Pascasarjana Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (289.42 KB) | DOI: 10.24114/jpkim.v12i2.19398

Abstract

The purpose of this study was to determine the antimicrobial activity of rosella infusa (Hibiscus sabdariffa L.). Antimicrobial inhibition test using infusa of rosella (Hibiscus sabdariffa L.) against Staphylococcus aureus and Escherichia coli bacteria at a concentration of infusa 100%; 75%; and 50%. The concentration has highest potential antibacterial of infusa for Staphylococcus aureus is 100% witch has diameter of 13.6 mm and for Escherichia coli bacteria is 100%, its show that diameter of zone inhibitory zone is 13.3 mm. The Results of phytochemical screening show that infusa of rosella (Hibiscus sabdariffa L.) contains flavonoids, saponins, and tannins. Based on the data above show that the infusa of rosella flower has high antibacterial potential. Keywords: Hibiscus sabdariffa L., antimicrobial activity, Staphylococcus aureus, Escherichia coli
Uji Aktivitas Antijamur Ekstrak Etanol Herba Patikan Kebo (Euphorbia hirta L.) Terhadap Candida albicans Helen Anjelina Simanjuntak; Hermawan Purba; Wan Yuli Anjani; Rahmiati Rahmiati; Toberni S Situmorang
Journal of Natural Sciences Vol 3, No 3 (2022): Journal of Natural Sciences November
Publisher : Mahesa Research Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34007/jonas.v3i3.303

Abstract

The patikan kebo plant is used to cure respiratory infections, malaria, liver, hypertension, gastrointestinal, skin diseases, accelerate wound healing, antidotes, hepatitis, rheumatism and tumors. The purpose of this study was to determine the antifungal activity of patikan kebo. The research method was carried out experimentally with the paper disc diffusion method. The antifungal activity test of each concentration (1%, 2%, 3%, 4%, ketoconazole, DMSO) had respective values (7.14 mm, 7.67 mm, 8.51 mm, 8.80 mm, 26.81 mm, 0 mm). The content of secondary metabolites in the patikan kebo plant are saponins, tannins, alkaloids, steroids/triterpenoids and flavonoids. The patikan kebo plant has medium category antifungal potential.
PENYULUHAN PROGRAM PHBS CUCI TANGAN DI SD NEGERI 106165 MARINDAL I DELI SERDANG Sahat Sinaga; Lydia Br. Barus; Nurbaiti Br. Singarimbun; Defacto Firmawati Zega; Helen Anjelina Simanjuntak; Hermawan Purba
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 1 (2023): Volume 4 Nomor 1 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i2.12062

Abstract

The degree of public health can be seen from the level of health. Efforts to improve health can be done by implementing the Clean and Healthy Living Behavior hand washing program in the school environment. Hand washing is carried out with the aim of being clean and can have an impact on preventing infectious diseases such as infections that cause diarrhea, Covid-19, intestinal worms, respiratory infections and other infections. So it is necessary to carry out community service activities in the form of Clean and Healthy Living Behavior counseling to 28 class II students at SD Negeri 106165 Marindal I Deli Serdang Regency as one of the efforts to prevent the spread of infectious diseases in the school environment which will later have an impact on the home and in the community. The activity method is carried out by lectures, questions and answers, demonstrations and evaluations. The results of the activity showed that there was an increase in students' knowledge about hand washing, the impact of not washing hands and how to wash hands properly and correctly. There are several factors that support the implementation of Clean and Healthy Living Behavior hand washing in schools, namely; the existence of teacher support, peer support, and hygiene facilities in washing hands.
Validasi Metode Analisa Kadar Fenolik Ekstrak Etanol Jahe Merah (Zingiber officinale var rubrum rhizoma) dengan Spektroscopy UV-Vis Hermawan Purba; Bonar Sinaga; Junius Gian Ginting
Herbal Medicine Journal Vol 6 No 1 (2023): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v6i1.78

Abstract

A validation study of the phenolic content analysis method has been carried out using the Galic acid method for jahe merah. Jahe merah in this study was previously characterized microscopically and macroscopically and a filter phytochemical test was carried out to determine the content of secondary metabolites in jahe merah. Furthermore, extraction is carried out by the maceration method. The resulting extract was then analyzed to determine the phenolic content in the sample. Determination of phenolic content uses a method that has been calibrated first, which includes linearity, LOD and LOQ, precision, accuracy, and sensitivity. The results of the analysis of the analytical parameters are as follows: linearity = 0.9909, Precision = 0.046; 0.06; 0.019 recovery = 98 and 102 %, sensitivity = 1.02. 105 L. Mol-1 cm-1. Analysis of the phenolic sample of the sample showed a concentration value of 180,2 mg GAE/gram jahe extract.
Edukasi Pencegahan Stunting Pada Anak di Desa Mekar Sari Kecamatan Delitua Kabupaten Deli Serdang Sarma Dewi Kemala; Sahat Sinaga; Junius Gian Ginting; Hermawan Purba; Dame Meldaria Sipahutar; Afrida Yelni
Jurnal Pengabdian Masyarakat Bangsa Vol. 1 No. 6 (2023): Agustus
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v1i6.268

Abstract

Stunting merupakan masalah kesehatan yang berdampak pada penurunan kualitas sumber daya manusia. Stunting ditandai dengan tinggi badan lebih pendek dan berat badan rebih rendah dari normal. Salah satu upaya pencegahan stunting adalah memberikan edukasi kepada masyarakat terutama para ibu di Desa Mekar Sari Kecamatan Delitua Kabupaten Deli Serdang. Kegiatan pengabdian bertujuan untuk memberikan pengetahuan dan wawasan kepada orang tua terutama Ibu dalam hal mencegah stunting melalui sosialisasi pemberian makanan gizi seimbang, pemberian ASI Ekslusif dan perilaku hidup bersih dan sehat. Kegiatan dilaksanakan pada hari Sabtu 24 Juni 2023 di rumah warga. Hasil kegiatan dihadiri oleh 25 orang ibu yang telah mampu memahami kegiatan pencegahan stunting melalui pemberian makanan bergizi, pemberian ASI Ekslusif dan tindakan sanitasi.
Potensi Buah Andaliman (Zanthoxylum acanthopodium DC.) sebagai Antibakteri Terhadap Salmonella typhi Helen Anjelina Simanjuntak; Hermawan Purba; Cander Pasaribu; Junius Gian Ginting; Rahmiati Rahmiati; Toberni S Situmorang
Journal of Natural Sciences Vol 4, No 2 (2023): Journal of Natural Sciences Juli
Publisher : Mahesa Research Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34007/jonas.v4i2.404

Abstract

Typhoid fever is a major disease of death in the medical field caused by Salmonella typhi infection with symptoms including fever, mucosal lesions, vomiting, diarrhea, fluid loss, septicemia, and peritonitis. The use of natural plants to cure infectious diseases such as andaliman fruit. The aim of this study was to determine the antibacterial activity of Andaliman fruit extract on the growth of Salmonella typhi. Experimental research method. The Kirby-bauer method was used for the antibacterial test, the maceration method was used for extraction. The results of phytochemical compounds found flavonoids, tanins, saponins, tannins, alkaloids steroids, and triterpenoids in simplicia and andaliman fruit extracts. All extracts have the potential to inhibit the growth of Salmonella typhi, with the diameter of the inhibition zone consisting of 10.04 mm, 12.22 mm, 15.46 mm and 16.68 mm in the strong category. These doses are 10%, 30%, 50%, and 70%. The analysis shows the potential of Andaliman fruit extract as an antibiotic in the treatment of typhoid fever.
OPTIMALISASI MANFAAT MINYAK KARO DI DESA TANGKAHAN Helen Anjelina Simanjuntak; Hermawan Purba; Defacto Firmawati Zega; Junius Gian Ginting
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 4 (2023): Volume 4 Nomor 4 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i4.20427

Abstract

Minyak karo merupakan produk minyak olahan yang dihasilkan oleh masyarakat suku karo yang telah diwariskan secara turun-temurun. Minyak karo berbahan herbal yang digunakan oleh masyarakat suku karo terutama dalam menjaga kesehatan dan pengobatan terutama dalam mengobati masuk angin, pegal linu, terkilir, pergeseran sendi, asam lambung, sakit kepala, alergi, mengobati luka, gatal-gatal dan disengat hewan berbisa. Desa Tangkahan merupakan salah satu desa dengan mayoritas dihuni oleh masyarakat suku karo dengan pekerjaan utama sebagai petani. Beberapa diantara memiliki potensi sebagai pengobat/peracik minyak karo, akan tetapi tidak dikembangkan secara optimal. Kegiatan bertujuan untuk memberikan informasi kepada masyarakat tentang manfaat minyak karo serta cara mengoptimalkannya. Metode kegiatan berupa seminar dan sosialisasi kepada masyarakat tentang manfaat minyak karo serta cara mengoptimalkannya melalui aspek kesehatan, dan aspek pengolahan. Kegiatan dihadiri oleh 40 peserta. Hasil kegiatan menunjukkan adanya antusias dari masyarakat tentang optimalisasi minyak karo melalui pendekatan aspek manfaat dalam kesehatan serta aspek pengolahan yang optimal.
Optimation of Green Synthesis Biopolymer Cellulose Using Acetobacter xylinum From Whey as Media of Bacteria Suharni Sinaga; Junius Gian Ginting; Helen Anjelina Simanjuntak; Dame Meldaria sipahutar; Defacto Firmawai Zega; Yanti Yanti; Sahat Sinaga; Lydia Barus; Hermawan Purba
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS (JPBN) Vol 9, No 3 (2023): Jurnal Pembelajaran Dan Biologi Nukleus November 2023
Publisher : Fakultas Keguruan dan Ilmu Pendidikan Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v9i3.5067

Abstract

Utilizing waste into a more valuable commodity was one of the objectives of that research. Waste which initially became an environmental pollutant factor could be processed into more useful products. Tofu liquid waste was referred to whey was a by-product of tofu production. Whey was waste that still contains organic materials such as protein, fat, carbohydrates and minerals. That whey was used as a growth medium for Acetobacter xylinum bacteria and produces cellulose biopolymer as a result of carbohydrate fermentation. The process of optimizing carbohydrate fermentation by Acetobacter xylinum bacteria was carried out by varying the ratio of the amount of whey to coconut water, the acidity level of the media, and the fermentation time. The research results showed that the biosynthesis of cellulose biopolymer was obtained from a ratio of whey concentration to coconut water of 1:1, variations in acidity levels showed that the optimum fermentation conditions occurred at pH 4, and the optimal amount of cellulose biopolymer was obtained on day 21, namely with the highest percent yield value. The resulting biocellulose was characterized using FTIR, XRD, and SEM. The characterization results show that biocellulose is well formed with a fiber surface shape and particle size in the range of 50-200 nm
PENETAPAN KADAR FLAVONOID EKSTRAK ETANOL DAN ETIL ASETAT DAUN MANGGIS (Garcinia mangostana L.) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Ginting, Junius Gian; Simanjuntak, Helen Anjelina; Purba, Hermawan
Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi Vol 24, No 2 (2024)
Publisher : LPPM Universitas Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jkbth.v24i2.1410

Abstract

In traditional medicine, mangosteen leaves (Garcinia mangostana L.) are useful in treating diabetes, hypertension, diarrhea, dysentery, and urinary tract problems. The study aims to determine the levels of flavonoids in mangosteen leaves with 96% ethanol and ethyl acetate. The total flavonoid content was determined by UV-Vis spectrophotometry, and the maceration process on the extract using 96% ethanol and ethyl acetate. The results of phytochemical screening of mangosteen leaf extract with 96% ethanol and ethyl acetate contained flavonoids, alkaloids, saponins, tannins and steroids/triterpenoids. The total flavonoid content in 96% ethanol solvent was 50.110 mgQE/gram extract and the total flavonoid content in ethyl acetate solvent was 118.773 in the extract. Ethyl acetate solvent is more effective in attracting flavonoid compounds in mangosteen leaves.
PENETAPAN KADAR FLAVONOID DAN TANIN EKSTRAK ETANOL DAUN NANGKA (Artocarpus heterophyllus Lam.) DENGAN SPEKTROFOTOMETRI UV-VIS Wahyuni, Sri; Simanjuntak, Helen Anjelina; Purba, Hermawan; Ginting, Junius Gian
Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi Vol 24, No 2 (2024)
Publisher : LPPM Universitas Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jkbth.v24i2.1405

Abstract

Jackfruit (Artocarpus heterophyllus Lam.) belongs to the moraceae family. Traditionally, jackfruit is used to treat fever, convulsions, asthma, diarrhea, anemia, cough and inflammation. The presence of flavonoid and tannin compounds isolated from jackfruit leaves has pharmacological activity in health. The purpose of this study was to screen the phytochemicals of secondary metabolites of flavonoids and tannins, and to determine the levels of secondary metabolites of flavonoids and tannins in jackfruit leaves using uv-vis spectrophotometry. The stages of this study began with sample collection, extraction, phytochemical screening, and testing of flavonoid and tannin levels. The results of phytochemical screening showed the presence of alkaloids, flavonoids, tannins, saponins, and steroids/triterpenoids in the crude drug and jackfruit leaf extract. The total flavonoid content was 234.9 mgQE/g with an R2 value of 0.9916, and for measuring the total tannin content was 343.3 mgTAE/g with an R2 value of 0.9956. The conclusion of this study is that the ethanol extract of jackfruit leaves contains flavonoid and tannin compounds with a total flavonoid content of 234.9 mgQE/g and a total tannin content of 343.3 mgTAE/g.
Co-Authors Afrida Yelni Anggreni, Wulan Barus, Syafril Bonar Sinaga Br. Gultom, Sesilia Sri Susandri Cander Pasaribu Daeli, Mestika Clemesiya Yulianti Dame Meldaria sipahutar Dame Meldaria Sipahutar Defacto Firmawai Zega Defacto Firmawati Zega Faneca, Egia Ginting, Junius Gian Gresela, Paula Helen Anjelina Simanjuntak Iksen, Iksen Ismadi Sihombing Kemala, Sarma Dewi Lydia Br Barus Manalu, Tiodora Manihuruk, Fani Nuryana Mayranti, Dwi Nahampun, Laura Yunita Purba, Sanna Kamisna Royani Rahmiati Rahmiati Risanti Situmorang Sahat Sinaga Sahat Sinaga Sahat Sinaga Sari, Mesi Puspita Sarma Dewi Kemala Sembiring, Mahral Effendi Sihotang, Santyria Simanjuntak, Herlina Sinaga, Sahat Sinaga, Suharni Pintamas Singarimbun, Nurbaiti Br Suharni Sinaga Toberni S Situmorang Toberni S Situmorang Toberni S Situmorang Wahyuni, Sri Wan Yuli Anjani Yanti Yanti Zalukhu, Historis Zega, Defcato Firmawati