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Testing The Antimicrobial Effectiveness of Manila Sauce Leaves (Manilkara Zapota L) against Bacteria Escherichia Coli: In Vitro Study Azizah, Namirah Nurjiranah; Kartika, Irna Diyana; Hasbi, Berry Erida; Muchtar, Amrizal; Arsal, Andi St. Fahirah
Journal La Lifesci Vol. 5 No. 2 (2024): Journal La Lifesci
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallalifesci.v5i2.1173

Abstract

Diarrhea remains a significant public health concern globally, particularly affecting children under five years old. Traditional herbal remedies, including Manila Sapodilla (Manilkara zapota L) leaves, have been utilized in Indonesia for treating diarrhea due to their perceived efficacy and safety. This in vitro study aimed to assess the antimicrobial effectiveness of Manila Sapodilla leaf extract against Escherichia coli bacteria, a common cause of diarrhea. True experimental design was employed, utilizing various concentrations (25%, 50%, 75%, and 100%) of Manila Sapodilla leaf extract. The extract was obtained through maceration using ethanol followed by dilution with distilled water. Antimicrobial activity was evaluated using the Kirby-Bauer diffusion method, measuring inhibition zones formed around Escherichia coli colonies. Results demonstrated that Manila Sapodilla leaf extract exhibited inhibitory effects against Escherichia coli at all tested concentrations, albeit with varying degrees of effectiveness. The inhibition zones ranged from 5.37 mm to 8.53 mm, indicating resistance. Positive control using Ciprofloxacin displayed a significantly larger inhibition zone (21.75 mm), indicating sensitivity. These findings suggest the potential of Manila Sapodilla leaf extract as an alternative treatment for Escherichia coli infections. However, further research, including phytochemical analysis and exploration of different extraction methods and concentrations, is warranted to elucidate its therapeutic potential fully. This study contributes to the ongoing search for alternative herbal-based antibiotics to combat bacterial infections effectively.
PELATIHAN PEMANFAATAN TUMBUHAN LERAK SEBAGAI BAHAN DASAR SABUN PENCUCI PERHIASAN EMAS PADA PENGUSAHA WANITA DI KOTA MAKASSAR Arsal, Andi Faridah; Arsal, Andi St. Fatmah; Arsal, Andi St. Fahirah; Syamsiah, Syamsiah; Kusdianawati, Kusdianawati
Jurnal Abdi Negeriku Vol 4, No 1 (2025): Jurnal Abdi Negeriku
Publisher : Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/jan.v4i1.74184

Abstract

Training on the use of soap leraks as a basic ingredient for gold jewelry washing soap aims to increase knowledge, popularize, and inspire people in Makassar City, especially women entrepreneurs, to reuse soap leraks as a natural soap ingredient. This training for the community is to increase knowledge and be able to reuse natural ingredients in their application in everyday life. The methods that have been carried out in this activity in stages include lectures for material presentation with an introduction to materials and how to manage them, demonstrations and direct practice, and discussions. The results of the training showed a positive response from the participants. The results of the activity showed that the community already knew about the use of soap leraks as a gold washing soap ingredient and its other benefits. In addition to the use of soap leraks as a soap ingredient, the community can independently use it according to their needs and applications. All participants have the skills and knowledge so that the opportunities for the use of soap leraks as a jewelry washing soap are increasingly wide open to the cultivation of soap leraks. During the activity, all participants showed very high enthusiasm for this training activity. Keywords: Lerak, Natural Ingredients, Soap   ABSTRAK Pelatihan pemanfaatan tumbuhan lerak sebagai bahan dasar sabun pencuci perhiasan emas bertujuan untuk meningkatkan pengetahuan, mempopulerkan, dan menggugah masyarakat di Kota Makassar khususnya pada pengusaha wanita dalam memanfaatkan kembali lerak sebagai bahan alami sabun. Pelatihan kepada masyarakat ini untuk meningkatkan pengetahuan dan dapat memanfaatkan kembali bahan  alami dalam penerapannya di kehidupan sehari-hari. Metode yang telah dilakukan dalam kegiatan ini secara bertahap meliputi ceramah untuk pemaparan materi dengan pengenalan bahan-bahan dan cara kerja pengelolaan, demostrasi serta praktik langsung, dan diskusi. Hasil pelatihan menunjukkan respons positif dari peserta. Hasil kegiatan menunjukkan bahwa masyarakat sudah mengetahui pemanfaatan lerak sebagai bahan sabun pencuci emas serta manfaat lainnya. Selain pemanfaatan lerak sebagai bahan sabun, secara mandiri masyarakat dapat memanfaatkannya sesuai dengan kebutuhan dan penerapannya. Seluruh peserta telah memiliki keterampilan dan pengetahuan sehingga peluang untuk pemanfaatan lerak sebagai sabun pencuci perhiasan semakin terbuka lebar hingga pada usaha budidaya tumbuhan lerak. Selama kegiatan berlangsung seluruh peserta menunjukkan antusiasme sangat tinggi terhadap kegiatan pelatihan ini.                                                                                                                                   Kata Kunci: Buah Lerak, Bahan Alami, Sabun